1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	F	G	Q	W	E	F	D	V	S	P	T	G	G	I	A	V	A	S	T	E	V	E	H	F	A	G	S	Q	H	E	V	D	T	A	E	V	P	S	A	A	W	G	W	S	R	I	D	H	R	T	W	H	I	V	G	L	C	I	F
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?						?							?	?	?	?	?	?	?	?	?	?	?	?	?											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.
Sequence		G	F	L	L	A	M	L	R	G	N	H	V	G	H	V	E	D	W	F	L	I	T	F	A	A	V	V	L	F	V	L	A	R	D	L	W	G	R	R	R	G	W	I	R
Secondary structure
SS confidence
Disorder																																							?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 28%) Alpha helix ( 45%) Beta strand ( 15%) TM helix ( 33%) (View membrane topology prediction)

Rank Aligned region

PDB 6adq chain P Region: 21 - 104 Aligned: 80 Modelled: 84 Confidence: 100.0% Identity: 61% PDB header:electron transport Chain: P: PDB Molecule:prokaryotic respiratory supercomplex associate factor 1 PDBTitle: respiratory complex ciii2civ2sod2 from mycobacterium smegmatis Phyre2 PDB 2rmz chain A Region: 78 - 100 Aligned: 23 Modelled: 23 Confidence: 59.7% Identity: 26% PDB header:cell adhesion Chain: A: PDB Molecule:integrin beta-3; PDBTitle: bicelle-embedded integrin beta3 transmembrane segment Phyre2 PDB 5n9y chain B Region: 59 - 103 Aligned: 45 Modelled: 45 Confidence: 59.1% Identity: 22% PDB header:membrane protein Chain: B: PDB Molecule:zinc transport protein zntb; PDBTitle: the full-length structure of zntb Phyre2 PDB 4ev6 chain E Region: 59 - 103 Aligned: 45 Modelled: 45 Confidence: 57.6% Identity: 20% PDB header:metal transport Chain: E: PDB Molecule:magnesium transport protein cora; PDBTitle: the complete structure of cora magnesium transporter from2 methanocaldococcus jannaschii Phyre2 PDB 5zaz chain A Region: 78 - 100 Aligned: 23 Modelled: 23 Confidence: 37.0% Identity: 22% PDB header:cell adhesion Chain: A: PDB Molecule:integrin beta-2; PDBTitle: solution structure of integrin b2 monomer tranmembrane domain in2 bicelle Phyre2 PDB 2ls2 chain A Region: 54 - 68 Aligned: 15 Modelled: 15 Confidence: 35.4% Identity: 40% PDB header:metal transport Chain: A: PDB Molecule:high affinity copper uptake protein 1; PDBTitle: 1h chemical shift assignments for the first transmembrane domain from2 human copper transport 1 Phyre2 PDB 2knc chain B Region: 78 - 100 Aligned: 23 Modelled: 23 Confidence: 33.9% Identity: 26% PDB header:cell adhesion Chain: B: PDB Molecule:integrin beta-3; PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex Phyre2 PDB 2mom chain B Region: 83 - 103 Aligned: 21 Modelled: 21 Confidence: 23.5% Identity: 24% PDB header:membrane protein Chain: B: PDB Molecule:lysosome-associated membrane glycoprotein 2; PDBTitle: structural insights of tm domain of lamp-2a in dpc micelles Phyre2 PDB 2mom chain C Region: 83 - 103 Aligned: 21 Modelled: 21 Confidence: 23.4% Identity: 24% PDB header:membrane protein Chain: C: PDB Molecule:lysosome-associated membrane glycoprotein 2; PDBTitle: structural insights of tm domain of lamp-2a in dpc micelles Phyre2 PDB 1eu1 chain A domain 1 Region: 21 - 41 Aligned: 21 Modelled: 21 Confidence: 15.3% Identity: 33% Fold: Double psi beta-barrel Superfamily: ADC-like Family: Formate dehydrogenase/DMSO reductase, C-terminal domain Phyre2 PDB 5iqj chain B Region: 67 - 84 Aligned: 18 Modelled: 18 Confidence: 14.5% Identity: 33% PDB header:unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: 1.9 angstrom crystal structure of protein with unknown function from2 vibrio cholerae. Phyre2 PDB 2d3a chain J Region: 3 - 18 Aligned: 16 Modelled: 16 Confidence: 12.2% Identity: 56% PDB header:ligase Chain: J: PDB Molecule:glutamine synthetase; PDBTitle: crystal structure of the maize glutamine synthetase2 complexed with adp and methionine sulfoximine phosphate Phyre2 PDB 4p5n chain B Region: 69 - 78 Aligned: 10 Modelled: 10 Confidence: 11.5% Identity: 50% PDB header:structural genomics Chain: B: PDB Molecule:hypothetical protein cnag_02591; PDBTitle: structure of cnag_02591 from cryptococcus neoformans Phyre2 PDB 2w2e chain A Region: 29 - 96 Aligned: 68 Modelled: 68 Confidence: 10.6% Identity: 21% PDB header:membrane protein Chain: A: PDB Molecule:aquaporin pip2-7 7; PDBTitle: 1.15 angstrom crystal structure of p.pastoris aquaporin, aqy1, in a2 closed conformation at ph 3.5 Phyre2 PDB 4bax chain H Region: 3 - 18 Aligned: 16 Modelled: 16 Confidence: 9.4% Identity: 50% PDB header:ligase Chain: H: PDB Molecule:glutamine synthetase; PDBTitle: crystal structure of glutamine synthetase from streptomyces2 coelicolor Phyre2 PDB 4is4 chain G Region: 3 - 18 Aligned: 16 Modelled: 16 Confidence: 9.2% Identity: 56% PDB header:ligase Chain: G: PDB Molecule:glutamine synthetase; PDBTitle: the glutamine synthetase from the dicotyledonous plant m. truncatula2 is a decamer Phyre2 PDB 2xcz chain A Region: 36 - 46 Aligned: 11 Modelled: 11 Confidence: 8.6% Identity: 45% PDB header:immune system Chain: A: PDB Molecule:possible atls1-like light-inducible protein; PDBTitle: crystal structure of macrophage migration inhibitory factor homologue2 from prochlorococcus marinus Phyre2 PDB 3gac chain D Region: 36 - 46 Aligned: 11 Modelled: 11 Confidence: 8.2% Identity: 9% PDB header:cytokine Chain: D: PDB Molecule:macrophage migration inhibitory factor-like PDBTitle: structure of mif with hpp Phyre2 PDB 6cuq chain B Region: 36 - 46 Aligned: 11 Modelled: 11 Confidence: 8.2% Identity: 27% PDB header:cytokine Chain: B: PDB Molecule:macrophage migration inhibitory factor-like protein; PDBTitle: crystal structure of macrophage migration inhibitory factor-like2 protein (ehmif) from entamoeba histolytica Phyre2 PDB 4c84 chain B Region: 7 - 47 Aligned: 41 Modelled: 41 Confidence: 7.8% Identity: 27% PDB header:ligase Chain: B: PDB Molecule:e3 ubiquitin-protein ligase znrf3; PDBTitle: zebrafish znrf3 ectodomain crystal form i Phyre2 1 c6adqP_ 2 c2rmzA_ 3 c5n9yB_ 4 c4ev6E_ 5 c5zazA_ 6 c2ls2A_ 7 c2kncB_ 8 c2momB_ 9 c2momC_ 10 d1eu1a1 11 c5iqjB_ 12 c2d3aJ_ 13 c4p5nB_ 14 c2w2eA_ 15 c4baxH_ 16 c4is4G_ 17 c2xczA_ 18 c3gacD_ 19 c6cuqB_ 20 c4c84B_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42