1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	N	F	T	A	A	D	V	K	R	L	R	E	L	T	G	A	G	M	L	A	C	K	N	A	L	A	E	T	D	G	D	F	D	K	A	V	E	A	L	R	I	K	G	A	K	D	V	G	K	R	A	E	R	A	T	A	E	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?												?														?																					?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	V	A	A	K	D	G	A	L	I	E	L	N	C	E	T	D	F	V	A	K	N	A	E	F	Q	T	L	A	D	Q	V	V	A	A	A	A	A	A	K	P	A	D	V	D	A	L	K	G	A	S	I	G	D	K	T	V	E	Q	A
Secondary structure
SS confidence
Disorder																																																		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		I	A	E	L	S	A	K	I	G	E	K	L	E	L	R	R	V	A	I	F	D	G	T	V	E	A	Y	L	H	R	R	S	A	D	L	P	P	A	V	G	V	L	V	E	Y	R	G	D	D	A	A	A	A	H	A	V	A	L	Q	I
Secondary structure
SS confidence
Disorder								?	?																									?	?		?												?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	A	L	R	A	R	Y	L	S	R	D	D	V	P	E	D	I	V	A	S	E	R	R	I	A	E	E	T	A	R	A	E	G	K	P	E	Q	A	L	P	K	I	V	E	G	R	L	N	G	F	F	K	D	A	V	L	L	E	Q	A
Secondary structure
SS confidence
Disorder										?					?																	?	?	?	?	?							?					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.
Sequence		S	V	S	D	N	K	K	T	V	K	A	L	L	D	V	A	G	V	T	V	T	R	F	V	R	F	E	V	G	Q	A
Secondary structure
SS confidence
Disorder				?	?																									?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 14%) Alpha helix ( 50%) Beta strand ( 19%)

Rank Aligned region

PDB 1efu chain B Region: 2 - 270 Aligned: 257 Modelled: 269 Confidence: 100.0% Identity: 41% PDB header:complex (two elongation factors) Chain: B: PDB Molecule:elongation factor ts; PDBTitle: elongation factor complex ef-tu/ef-ts from escherichia coli Phyre2 PDB 3mmp chain C Region: 4 - 270 Aligned: 255 Modelled: 267 Confidence: 100.0% Identity: 41% PDB header:transferase Chain: C: PDB Molecule:elongation factor tu 2, elongation factor ts; PDBTitle: structure of the qb replicase, an rna-dependent rna polymerase2 consisting of viral and host proteins Phyre2 PDB 3agq chain A Region: 5 - 270 Aligned: 254 Modelled: 266 Confidence: 100.0% Identity: 42% PDB header:translation,transferase Chain: A: PDB Molecule:elongation factor ts, elongation factor tu 1, linker, q PDBTitle: structure of viral polymerase form ii Phyre2 PDB 1xb2 chain B Region: 2 - 270 Aligned: 247 Modelled: 264 Confidence: 100.0% Identity: 28% PDB header:translation Chain: B: PDB Molecule:elongation factor ts, mitochondrial; PDBTitle: crystal structure of bos taurus mitochondrial elongation2 factor tu/ts complex Phyre2 PDB 1aip chain G Region: 5 - 269 Aligned: 181 Modelled: 181 Confidence: 100.0% Identity: 56% PDB header:complex of two elongation factors Chain: G: PDB Molecule:elongation factor ts; PDBTitle: ef-tu ef-ts complex from thermus thermophilus Phyre2 PDB 1efu chain B domain 2 Region: 143 - 270 Aligned: 122 Modelled: 128 Confidence: 100.0% Identity: 34% Fold: EF-Ts domain-like Superfamily: Elongation factor Ts (EF-Ts), dimerisation domain Family: Elongation factor Ts (EF-Ts), dimerisation domain Phyre2 PDB 1tfe chain A Region: 141 - 269 Aligned: 124 Modelled: 129 Confidence: 100.0% Identity: 41% Fold: EF-Ts domain-like Superfamily: Elongation factor Ts (EF-Ts), dimerisation domain Family: Elongation factor Ts (EF-Ts), dimerisation domain Phyre2 PDB 1xb2 chain B domain 2 Region: 54 - 143 Aligned: 90 Modelled: 90 Confidence: 99.9% Identity: 31% Fold: EF-Ts domain-like Superfamily: Elongation factor Ts (EF-Ts), dimerisation domain Family: Elongation factor Ts (EF-Ts), dimerisation domain Phyre2 PDB 1efu chain B domain 4 Region: 56 - 142 Aligned: 81 Modelled: 87 Confidence: 99.9% Identity: 46% Fold: EF-Ts domain-like Superfamily: Elongation factor Ts (EF-Ts), dimerisation domain Family: Elongation factor Ts (EF-Ts), dimerisation domain Phyre2 PDB 1xb2 chain B domain 3 Region: 143 - 271 Aligned: 96 Modelled: 101 Confidence: 99.9% Identity: 26% Fold: EF-Ts domain-like Superfamily: Elongation factor Ts (EF-Ts), dimerisation domain Family: Elongation factor Ts (EF-Ts), dimerisation domain Phyre2 PDB 1efu chain B domain 3 Region: 2 - 55 Aligned: 54 Modelled: 54 Confidence: 99.8% Identity: 50% Fold: RuvA C-terminal domain-like Superfamily: UBA-like Family: TS-N domain Phyre2 PDB 1aip chain C domain 1 Region: 5 - 55 Aligned: 51 Modelled: 51 Confidence: 99.8% Identity: 45% Fold: RuvA C-terminal domain-like Superfamily: UBA-like Family: TS-N domain Phyre2 PDB 1xb2 chain B domain 1 Region: 2 - 56 Aligned: 55 Modelled: 55 Confidence: 99.8% Identity: 27% Fold: RuvA C-terminal domain-like Superfamily: UBA-like Family: TS-N domain Phyre2 PDB 2cp9 chain A domain 1 Region: 5 - 54 Aligned: 50 Modelled: 50 Confidence: 99.7% Identity: 28% Fold: RuvA C-terminal domain-like Superfamily: UBA-like Family: TS-N domain Phyre2 PDB 2mro chain B Region: 2 - 41 Aligned: 39 Modelled: 40 Confidence: 97.0% Identity: 33% PDB header:transport protein/signaling protein Chain: B: PDB Molecule:dna damage-inducible protein 1; PDBTitle: structure of the complex of ubiquitin and the uba domain from dna-2 damage-inducible 1 protein (ddi1) Phyre2 PDB 1ify chain A Region: 7 - 41 Aligned: 34 Modelled: 35 Confidence: 96.8% Identity: 21% Fold: RuvA C-terminal domain-like Superfamily: UBA-like Family: UBA domain Phyre2 PDB 1tr8 chain A Region: 3 - 41 Aligned: 39 Modelled: 39 Confidence: 96.7% Identity: 31% PDB header:chaperone Chain: A: PDB Molecule:conserved protein (mth177); PDBTitle: crystal structure of archaeal nascent polypeptide-associated complex2 (aenac) Phyre2 PDB 1wiv chain A Region: 2 - 41 Aligned: 39 Modelled: 40 Confidence: 96.5% Identity: 23% Fold: RuvA C-terminal domain-like Superfamily: UBA-like Family: UBA domain Phyre2 PDB 1veg chain A Region: 2 - 45 Aligned: 43 Modelled: 44 Confidence: 96.4% Identity: 21% Fold: RuvA C-terminal domain-like Superfamily: UBA-like Family: UBA domain Phyre2 PDB 2lva chain A Region: 8 - 41 Aligned: 34 Modelled: 34 Confidence: 96.1% Identity: 35% PDB header:hydrolase Chain: A: PDB Molecule:ubiquitin carboxyl-terminal hydrolase 28; PDBTitle: nmr solution structure of the n-terminal domain of human usp28,2 northeast structural genomics consortium target ht8470a Phyre2 1 c1efuB_ 2 c3mmpC_ 3 c3agqA_ 4 c1xb2B_ 5 c1aipG_ 6 d1efub2 7 d1tfea_ 8 d1xb2b2 9 d1efub4 10 d1xb2b3 11 d1efub3 12 d1aipc1 13 d1xb2b1 14 d2cp9a1 15 c2mroB_ 16 d1ifya_ 17 c1tr8A_ 18 d1wiva_ 19 d1vega_ 20 c2lvaA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99