1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	D	L	G	G	V	R	R	R	I	S	L	M	A	R	Q	H	G	P	T	A	Q	R	H	V	A	S	P	M	T	V	D	I	A	R	L	G	R	R	P	G	A	M	F	E	L	H	D	T	V	H	S	P	A	R	I	G	L	E	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?				?	?	?	?	?	?	?	?	?	?	?	?	?	?	?												?	?	?	?	?														?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		I	A	I	D	Q	G	A	L	L	D	L	D	L	R	V	E	S	V	S	E	G	V	L	V	T	G	T	V	A	A	P	T	V	G	E	C	A	R	C	L	S	P	V	R	G	R	V	Q	V	A	L	T	E	L	F	A	Y	P	D	S
Secondary structure
SS confidence
Disorder			?	?																																																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	T	D	E	T	T	E	E	D	E	V	G	R	V	V	D	E	T	I	D	L	E	Q	P	I	I	D	A	V	G	L	E	L	P	F	S	P	V	C	R	P	D	C	P	G	L	C	P	Q	C	G	V	P	L	A	S	E	P	G	H
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																																																		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.
Sequence		R	H	E	Q	I	D	P	R	W	A	K	L	V	E	M	L	G	P	E	S	D	T	L	R	G	E	R
Secondary structure
SS confidence
Disorder		?	?	?	?		?										?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 31%) Alpha helix ( 23%) Beta strand ( 31%)

Rank Aligned region

PDB 5iy9 chain Q Region: 166 - 198 Aligned: 33 Modelled: 33 Confidence: 28.3% Identity: 15% PDB header:transcription, transferase/dna/rna Chain: Q: PDB Molecule:general transcription factor iie subunit 1; PDBTitle: human holo-pic in the initial transcribing state (no iis) Phyre2 PDB 2c55 chain A Region: 177 - 203 Aligned: 26 Modelled: 27 Confidence: 23.3% Identity: 31% PDB header:viral protein Chain: A: PDB Molecule:protein p6; PDBTitle: solution structure of the human immunodeficiency virus type2 1 p6 protein Phyre2 PDB 5ezd chain B Region: 16 - 104 Aligned: 63 Modelled: 63 Confidence: 19.2% Identity: 22% PDB header:hydrolase Chain: B: PDB Molecule:kunitz-type protease inhibitor 1; PDBTitle: crystal structure of a hepatocyte growth factor activator inhibitor-12 (hai-1) fragment covering the pkd-like 'internal' domain and kunitz3 domain 1 Phyre2 PDB 1i7x chain D Region: 187 - 197 Aligned: 11 Modelled: 11 Confidence: 19.0% Identity: 45% PDB header:cell adhesion Chain: D: PDB Molecule:epithelial-cadherin; PDBTitle: beta-catenin/e-cadherin complex Phyre2 PDB 2dof chain A domain 1 Region: 186 - 195 Aligned: 10 Modelled: 10 Confidence: 18.0% Identity: 30% Fold: Another 3-helical bundle Superfamily: FF domain Family: FF domain Phyre2 PDB 1pfv chain A domain 3 Region: 164 - 188 Aligned: 25 Modelled: 25 Confidence: 18.0% Identity: 32% Fold: Rubredoxin-like Superfamily: Methionyl-tRNA synthetase (MetRS), Zn-domain Family: Methionyl-tRNA synthetase (MetRS), Zn-domain Phyre2 PDB 2l9v chain A Region: 186 - 195 Aligned: 10 Modelled: 10 Confidence: 16.4% Identity: 40% PDB header:rna binding protein Chain: A: PDB Molecule:pre-mrna-processing factor 40 homolog a; PDBTitle: nmr structure of the ff domain l24a mutant's folding transition state Phyre2 PDB 1i7w chain B Region: 187 - 196 Aligned: 10 Modelled: 10 Confidence: 15.8% Identity: 40% PDB header:cell adhesion Chain: B: PDB Molecule:epithelial-cadherin; PDBTitle: beta-catenin/phosphorylated e-cadherin complex Phyre2 PDB 1yuj chain A Region: 162 - 174 Aligned: 13 Modelled: 13 Confidence: 14.3% Identity: 31% Fold: beta-beta-alpha zinc fingers Superfamily: beta-beta-alpha zinc fingers Family: Classic zinc finger, C2H2 Phyre2 PDB 2a93 chain B Region: 4 - 12 Aligned: 9 Modelled: 9 Confidence: 13.9% Identity: 44% PDB header:leucine zippers Chain: B: PDB Molecule:c-myc-max heterodimeric leucine zipper; PDBTitle: nmr solution structure of the c-myc-max heterodimeric2 leucine zipper, 40 structures Phyre2 PDB 3d3r chain A domain 1 Region: 1 - 13 Aligned: 13 Modelled: 13 Confidence: 12.4% Identity: 54% Fold: OB-fold Superfamily: HupF/HypC-like Family: HupF/HypC-like Phyre2 PDB 3fqm chain A Region: 51 - 97 Aligned: 43 Modelled: 47 Confidence: 11.9% Identity: 23% PDB header:metal binding protein Chain: A: PDB Molecule:non-structural protein 5a; PDBTitle: crystal structure of a novel dimeric form of hcv ns5a domain i protein Phyre2 PDB 1j58 chain A Region: 14 - 95 Aligned: 82 Modelled: 82 Confidence: 11.8% Identity: 12% Fold: Double-stranded beta-helix Superfamily: RmlC-like cupins Family: Germin/Seed storage 7S protein Phyre2 PDB 2fiy chain A domain 1 Region: 143 - 172 Aligned: 30 Modelled: 30 Confidence: 11.5% Identity: 30% Fold: FdhE-like Superfamily: FdhE-like Family: FdhE-like Phyre2 PDB 2a90 chain A domain 2 Region: 24 - 53 Aligned: 30 Modelled: 30 Confidence: 10.4% Identity: 23% Fold: WWE domain Superfamily: WWE domain Family: WWE domain Phyre2 PDB 3d3r chain A Region: 1 - 13 Aligned: 13 Modelled: 13 Confidence: 10.4% Identity: 54% PDB header:chaperone Chain: A: PDB Molecule:hydrogenase assembly chaperone hypc/hupf; PDBTitle: crystal structure of the hydrogenase assembly chaperone hypc/hupf2 family protein from shewanella oneidensis mr-1 Phyre2 PDB 2z1c chain A domain 1 Region: 1 - 13 Aligned: 13 Modelled: 13 Confidence: 10.3% Identity: 54% Fold: OB-fold Superfamily: HupF/HypC-like Family: HupF/HypC-like Phyre2 PDB 5bux chain B Region: 63 - 98 Aligned: 36 Modelled: 36 Confidence: 9.5% Identity: 19% PDB header:lyase Chain: B: PDB Molecule:3-hydroxyacyl-[acyl-carrier-protein] dehydratase fabz; PDBTitle: crystal structure of 3-hydroxyacyl-acp dehydratase (fabz) from2 yersinia pestis with glycerol bound Phyre2 PDB 2n8d chain A Region: 186 - 197 Aligned: 12 Modelled: 12 Confidence: 9.4% Identity: 25% PDB header:de novo protein, antimicrobial peptide Chain: A: PDB Molecule:antimicrobial peptide lavracin; PDBTitle: in silico designed antimicrobial peptide lavracin Phyre2 PDB 5fyw chain W Region: 166 - 201 Aligned: 35 Modelled: 35 Confidence: 9.1% Identity: 23% PDB header:transcription Chain: W: PDB Molecule:transcription initiation factor iie subunit alpha; PDBTitle: transcription initiation complex structures elucidate dna opening (oc) Phyre2 1 c5iy9Q_ 2 c2c55A_ 3 c5ezdB_ 4 c1i7xD_ 5 d2dofa1 6 d1pfva3 7 c2l9vA_ 8 c1i7wB_ 9 d1yuja_ 10 c2a93B_ 11 d3d3ra1 12 c3fqmA_ 13 d1j58a_ 14 d2fiya1 15 d2a90a2 16 c3d3rA_ 17 d2z1ca1 18 c5buxB_ 19 c2n8dA_ 20 c5fywW_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43