Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD2942_(mmpL7)_3285080_3287842
DateThu Aug 8 16:20:10 BST 2019
Unique Job ID4c1243b0a1812732
SequenceMPSPAGRLHR ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:58.602 Y:84.091 Z:90.221
Model (left) based on template c6ajjA_
Top template information
PDB header:membrane protein, hydrolase
Chain: A: PDB Molecule:drug exporters of the rnd superfamily-like protein,
PDBTitle: crystal structure of mycolic acid transporter mmpl3 from mycobacterium2 smegmatis complexed with ica38
Confidence and coverage
Confidence:100.0% Coverage: 71%
650 residues ( 71% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
889 residues ( 97%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
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Sequence analysis 

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Secondary structure and disorder prediction [Show] 

Domain analysis [Show] 

Detailed template information [Hide] 

 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c6ajjA_
100.0 15
PDB header:membrane protein, hydrolase
Chain: A: PDB Molecule:drug exporters of the rnd superfamily-like protein,
PDBTitle: crystal structure of mycolic acid transporter mmpl3 from mycobacterium2 smegmatis complexed with ica38
2c5lq3F_
100.0 11
PDB header:transport protein
Chain: F: PDB Molecule:cmeb;
PDBTitle: structures and transport dynamics of the campylobacter jejuni2 multidrug efflux pump cmeb
3c3k07A_
100.0 12
PDB header:transport protein
Chain: A: PDB Molecule:cation efflux system protein cusa;
PDBTitle: crystal structure of cusa
4c6owsB_
100.0 12
PDB header:membrane protein
Chain: B: PDB Molecule:efflux pump membrane transporter;
PDBTitle: cryo-em structure of an acinetobacter baumannii multidrug efflux pump
5c4mt1A_
100.0 12
PDB header:membrane protein, tranport protein
Chain: A: PDB Molecule:drug efflux protein;
PDBTitle: crystal structure of the neisseria gonorrhoeae mtrd inner membrane2 multidrug efflux pump
6c2v50A_
100.0 12
PDB header:membrane protein
Chain: A: PDB Molecule:multidrug resistance protein mexb;
PDBTitle: the missing part of the bacterial mexab-oprm system: structural2 determination of the multidrug exporter mexb
7c1oy8A_
100.0 12
PDB header:membrane protein
Chain: A: PDB Molecule:acriflavine resistance protein b;
PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump
8c4k0eA_
100.0 14
PDB header:transport protein
Chain: A: PDB Molecule:heavy metal cation tricomponent efflux pump znea(czca-
PDBTitle: x-ray crystal structure of a heavy metal efflux pump, crystal form ii
9c5khnB_
100.0 16
PDB header:membrane protein
Chain: B: PDB Molecule:rnd transporter;
PDBTitle: crystal structures of the burkholderia multivorans hopanoid2 transporter hpnn
10c6csxA_
100.0 12
PDB header:transport protein
Chain: A: PDB Molecule:multidrug efflux pump subunit acrb;
PDBTitle: single particles cryo-em structure of acrb d407a associated with lipid2 bilayer at 3.0 angstrom
11c4k0eC_
100.0 14
PDB header:transport protein
Chain: C: PDB Molecule:heavy metal cation tricomponent efflux pump znea(czca-
PDBTitle: x-ray crystal structure of a heavy metal efflux pump, crystal form ii
12c6dmoA_
100.0 12
PDB header:protein binding
Chain: A: PDB Molecule:protein patched homolog 1;
PDBTitle: cryo-em structure of human ptch1 with three mutations2 l282q/t500f/p504l
13c3aqpB_
100.0 14
PDB header:membrane protein
Chain: B: PDB Molecule:probable secdf protein-export membrane protein;
PDBTitle: crystal structure of secdf, a translocon-associated membrane protein,2 from thermus thrmophilus
14c3jd8A_
100.0 15
PDB header:membrane protein
Chain: A: PDB Molecule:niemann-pick c1 protein;
PDBTitle: cryo-em structure of the full-length human npc1 at 4.4 angstrom
15c5xamA_
100.0 12
PDB header:membrane protein
Chain: A: PDB Molecule:protein translocase subunit secd;
PDBTitle: crystal structure of secdf in i form at 4 a resolution
16d1iwga8
99.9 10
Fold:Multidrug efflux transporter AcrB transmembrane domain
Superfamily:Multidrug efflux transporter AcrB transmembrane domain
Family:Multidrug efflux transporter AcrB transmembrane domain
17c5mg3D_
99.9 8
PDB header:chaperone
Chain: D: PDB Molecule:protein translocase subunit secd;
PDBTitle: em fitted model of bacterial holo-translocon
18c5mg3F_
99.8 13
PDB header:chaperone
Chain: F: PDB Molecule:protein translocase subunit secf;
PDBTitle: em fitted model of bacterial holo-translocon
19d1iwga7
99.8 14
Fold:Multidrug efflux transporter AcrB transmembrane domain
Superfamily:Multidrug efflux transporter AcrB transmembrane domain
Family:Multidrug efflux transporter AcrB transmembrane domain
20c5ensA_
99.3 13
PDB header:transport protein
Chain: A: PDB Molecule:multidrug efflux pump subunit acrb,multidrug efflux pump
PDBTitle: rhodamine bound structure of bacterial efflux pump.
21c4r86B_
not modelled 98.4 10
PDB header:protein transport
Chain: B: PDB Molecule:rnd family aminoglycoside/multidrug efflux pump;
PDBTitle: crystal structure of aminoglycoside/multidrug efflux system acrd from2 salmonella typhimurium
22d1iwga3
not modelled 90.5 13
Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
23d1iwga2
not modelled 82.1 8
Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
24d1iwga6
not modelled 74.4 8
Fold:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
25c4y0lA_
not modelled 33.7 22
PDB header:membrane protein
Chain: A: PDB Molecule:putative membrane protein mmpl11;
PDBTitle: mycobacterial membrane protein mmpl11d2
26d1iwga4
not modelled 28.2 10
Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
27c5v6xB_
not modelled 24.8 20
PDB header:ligase/rna
Chain: B: PDB Molecule:pyrrolysine--trna ligase;
PDBTitle: crystal structure of the trna binding domain of pyrrolysyl-trna2 synthetase mutant (32a ntd) bound to trna(pyl)
28c3n4dF_
not modelled 22.6 12
PDB header:hydrolase
Chain: F: PDB Molecule:putative tautomerase;
PDBTitle: crystal structure of cg10062 inactivated by(r)-oxirane-2-carboxylate
29c1ciiA_
not modelled 18.5 15
PDB header:transmembrane protein
Chain: A: PDB Molecule:colicin ia;
PDBTitle: colicin ia
30c4ev6E_
not modelled 18.2 4
PDB header:metal transport
Chain: E: PDB Molecule:magnesium transport protein cora;
PDBTitle: the complete structure of cora magnesium transporter from2 methanocaldococcus jannaschii
31c6adqP_
not modelled 16.7 20
PDB header:electron transport
Chain: P: PDB Molecule:prokaryotic respiratory supercomplex associate factor 1
PDBTitle: respiratory complex ciii2civ2sod2 from mycobacterium smegmatis
32c6b2zf_
not modelled 15.8 10
PDB header:membrane protein
Chain: F: PDB Molecule:atp synthase subunit c, mitochondrial;
PDBTitle: cryo-em structure of the dimeric fo region of yeast mitochondrial atp2 synthase
33c3j1zP_
not modelled 15.6 12
PDB header:metal transport
Chain: P: PDB Molecule:cation efflux family protein;
PDBTitle: inward-facing conformation of the zinc transporter yiip revealed by2 cryo-electron microscopy
34c6b8ht_
not modelled 15.1 10
PDB header:membrane protein
Chain: T: PDB Molecule:atp synthase subunit 9, mitochondrial;
PDBTitle: mosaic model of yeast mitochondrial atp synthase monomer
35c2m67A_
not modelled 14.7 10
PDB header:transport protein
Chain: A: PDB Molecule:merf;
PDBTitle: full-length mercury transporter protein merf in lipid bilayer2 membranes
36c2flzC_
not modelled 14.5 10
PDB header:hydrolase
Chain: C: PDB Molecule:cis-3-chloroacrylic acid dehalogenase;
PDBTitle: the x-ray structure of cis-3-chloroacrylic acid dehalogenase (cis-2 caad) with a sulfate ion bound in the active site
37c5gk9B_
not modelled 14.2 100
PDB header:transferase/metal binding protein
Chain: B: PDB Molecule:brd1 protein;
PDBTitle: crystal structure of human hbo1 in complex with brpf2
38d1pzra_
not modelled 12.9 19
Fold:HLH-like
Superfamily:Docking domain B of the erythromycin polyketide synthase (DEBS)
Family:Docking domain B of the erythromycin polyketide synthase (DEBS)
39d1a87a_
not modelled 12.5 11
Fold:Toxins' membrane translocation domains
Superfamily:Colicin
Family:Colicin
40c1a87A_
not modelled 12.5 11
PDB header:bacteriocin
Chain: A: PDB Molecule:colicin n;
PDBTitle: colicin n
41c4rhoA_
not modelled 12.1 13
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a hypothetical protein (bpsl2088) from2 burkholderia pseudomallei k96243 at 2.25 a resolution
42c4kppA_
not modelled 12.1 12
PDB header:membrane protein
Chain: A: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of h+/ca2+ exchanger cax
43c6f0kA_
not modelled 11.7 18
PDB header:membrane protein
Chain: A: PDB Molecule:cytochrome c family protein;
PDBTitle: alternative complex iii
44c3tijA_
not modelled 11.2 15
PDB header:membrane protein
Chain: A: PDB Molecule:nupc family protein;
PDBTitle: crystal structure of a concentrative nucleoside transporter from2 vibrio cholerae
45c2lj2A_
not modelled 11.1 11
PDB header:membrane protein
Chain: A: PDB Molecule:merf;
PDBTitle: integral membrane core domain of the mercury transporter merf in lipid2 bilayer membranes
46c2yvxD_
not modelled 10.9 14
PDB header:transport protein
Chain: D: PDB Molecule:mg2+ transporter mgte;
PDBTitle: crystal structure of magnesium transporter mgte
47c3tufA_
not modelled 10.6 8
PDB header:signaling protein
Chain: A: PDB Molecule:stage iii sporulation protein ah;
PDBTitle: structure of the spoiiq-spoiiiah pore forming complex.
48c2mkaB_
not modelled 10.0 11
PDB header:immune system
Chain: B: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the toll-like receptor 3 transmembrane domain in2 the trimeric state
49c2mkaC_
not modelled 10.0 11
PDB header:immune system
Chain: C: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the toll-like receptor 3 transmembrane domain in2 the trimeric state
50c2mk9B_
not modelled 10.0 11
PDB header:immune system
Chain: B: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the dimeric transmembrane domain of toll-like2 receptor 3
51c2mkaA_
not modelled 10.0 11
PDB header:immune system
Chain: A: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the toll-like receptor 3 transmembrane domain in2 the trimeric state
52c2mk9A_
not modelled 10.0 11
PDB header:immune system
Chain: A: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the dimeric transmembrane domain of toll-like2 receptor 3
53c2l35A_
not modelled 9.9 16
PDB header:protein binding
Chain: A: PDB Molecule:dap12-nkg2c_tm;
PDBTitle: structure of the dap12-nkg2c transmembrane heterotrimer
54c5xkrA_
not modelled 9.7 17
PDB header:hydrolase
Chain: A: PDB Molecule:cmp/dcmp deaminase, zinc-binding protein;
PDBTitle: crystal structure of msmeg3575 in complex with benzoguanamine
55d1gtra2
not modelled 9.3 63
Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain
56d1sd4a_
not modelled 9.2 9
Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Penicillinase repressor
57c5lj7B_
not modelled 9.1 16
PDB header:transport protein
Chain: B: PDB Molecule:macrolide export atp-binding/permease protein macb;
PDBTitle: structure of aggregatibacter actinomycetemcomitans macb bound to atp2 (p21)
58c3bb5B_
not modelled 9.0 7
PDB header:unknown function
Chain: B: PDB Molecule:stress responsive alpha-beta protein;
PDBTitle: crystal structure of a dimeric ferredoxin-like protein of unknown2 function (jann_3925) from jannaschia sp. ccs1 at 2.30 a resolution
59c6fkip_
not modelled 8.3 24
PDB header:membrane protein
Chain: P: PDB Molecule:atp synthase subunit c, chloroplastic;
PDBTitle: chloroplast f1fo conformation 3
60c5aj3m_
not modelled 8.3 44
PDB header:ribosome
Chain: M: PDB Molecule:
PDBTitle: structure of the small subunit of the mammalian mitoribosome
61c3w66A_
not modelled 8.1 10
PDB header:metal transport
Chain: A: PDB Molecule:magnetosome protein mamm;
PDBTitle: mamm-ctd d249a and h285a
62d1nzja_
not modelled 7.9 75
Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain
63d2cupa2
not modelled 7.8 15
Fold:Glucocorticoid receptor-like (DNA-binding domain)
Superfamily:Glucocorticoid receptor-like (DNA-binding domain)
Family:LIM domain
64c4p6vE_
not modelled 7.8 15
PDB header:oxidoreductase
Chain: E: PDB Molecule:na(+)-translocating nadh-quinone reductase subunit e;
PDBTitle: crystal structure of the na+-translocating nadh: ubiquinone2 oxidoreductase from vibrio cholerae
65d1kkga_
not modelled 7.8 16
Fold:Alpha-lytic protease prodomain-like
Superfamily:Ribosome-binding factor A, RbfA
Family:Ribosome-binding factor A, RbfA
66d1q4ra_
not modelled 7.3 12
Fold:Ferredoxin-like
Superfamily:Dimeric alpha+beta barrel
Family:Plant stress-induced protein
67c6nbxG_
not modelled 7.3 16
PDB header:oxidoreductase
Chain: G: PDB Molecule:nadh-quinone oxidoreductase subunit j;
PDBTitle: t.elongatus ndh (data-set 2)
68c5lj3P_
not modelled 7.2 15
PDB header:splicing
Chain: P: PDB Molecule:cwc15;
PDBTitle: structure of the core of the yeast spliceosome immediately after2 branching
69c3lw5H_
not modelled 7.2 10
PDB header:photosynthesis
Chain: H: PDB Molecule:putative uncharacterized protein;
PDBTitle: improved model of plant photosystem i
70c6f46A_
not modelled 7.1 22
PDB header:apoptosis
Chain: A: PDB Molecule:bcl-2-like protein 1;
PDBTitle: structure of the transmembrane helix of bclxl in phospholipid2 nanodiscs
71c3al0C_
not modelled 6.9 75
PDB header:ligase/rna
Chain: C: PDB Molecule:glutamyl-trna(gln) amidotransferase subunit c,linker,
PDBTitle: crystal structure of the glutamine transamidosome from thermotoga2 maritima in the glutamylation state.
72c2o5rA_
not modelled 6.9 75
PDB header:ligase
Chain: A: PDB Molecule:glutamyl-trna synthetase 1;
PDBTitle: crystal structure of glutamyl-trna synthetase 1 (ec 6.1.1.17)2 (glutamate-trna ligase 1) (glurs 1) (tm1351) from thermotoga maritima3 at 2.5 a resolution
73c3c6vB_
not modelled 6.8 11
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:probable tautomerase/dehalogenase au4130;
PDBTitle: crystal structure of au4130/apc7354, a probable enzyme from the2 thermophilic fungus aspergillus fumigatus
74d1ulza1
not modelled 6.7 19
Fold:Barrel-sandwich hybrid
Superfamily:Rudiment single hybrid motif
Family:BC C-terminal domain-like
75d1nwba_
not modelled 6.6 13
Fold:HesB-like domain
Superfamily:HesB-like domain
Family:HesB-like domain
76c4pf8A_
not modelled 6.6 11
PDB header:transport protein
Chain: A: PDB Molecule:trap-t family transporter, dctp (periplasmic binding)
PDBTitle: crystal structure of a trap periplasmic solute binding protein from2 sulfitobacter sp. nas-14.1 (target efi-510299) with bound beta-d-3 galacturonate
77d1josa_
not modelled 6.6 13
Fold:Alpha-lytic protease prodomain-like
Superfamily:Ribosome-binding factor A, RbfA
Family:Ribosome-binding factor A, RbfA
78c3afhA_
not modelled 6.6 75
PDB header:ligase
Chain: A: PDB Molecule:glutamyl-trna synthetase 2;
PDBTitle: crystal structure of thermotoga maritima nondiscriminating glutamyl-2 trna synthetase in complex with a glutamyl-amp analog
79c2wsfH_
not modelled 6.6 9
PDB header:photosynthesis
Chain: H: PDB Molecule:photosystem i reaction center subunit vi, chloroplastic;
PDBTitle: improved model of plant photosystem i
80c3cwcB_
not modelled 6.6 21
PDB header:transferase
Chain: B: PDB Molecule:putative glycerate kinase 2;
PDBTitle: crystal structure of putative glycerate kinase 2 from salmonella2 typhimurium lt2
81d1aopa2
not modelled 6.5 12
Fold:Ferredoxin-like
Superfamily:Nitrite/Sulfite reductase N-terminal domain-like
Family:Duplicated SiR/NiR-like domains 1 and 3
82d1j09a2
not modelled 6.5 63
Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain
83c3uz0A_
not modelled 6.5 8
PDB header:transport protein
Chain: A: PDB Molecule:stage iii sporulation protein ah;
PDBTitle: crystal structure of spoiiiah and spoiiq complex
84c5un4C_
not modelled 6.4 11
PDB header:hydrolase
Chain: C: PDB Molecule:4-oxalocrotonate tautomerase;
PDBTitle: crystal structure of native fused 4-ot
85c2k1aA_
not modelled 6.3 17
PDB header:cell adhesion
Chain: A: PDB Molecule:integrin alpha-iib;
PDBTitle: bicelle-embedded integrin alpha(iib) transmembrane segment
86c5u1dX_
not modelled 6.2 10
PDB header:transport protein
Chain: X: PDB Molecule:tap transporter inhibitor icp47;
PDBTitle: cryo-em structure of the human tap atp-binding cassette transporter
87d1fnda2
not modelled 6.2 5
Fold:Ferredoxin reductase-like, C-terminal NADP-linked domain
Superfamily:Ferredoxin reductase-like, C-terminal NADP-linked domain
Family:Reductases
88c5jrlC_
not modelled 6.2 21
PDB header:hydrolase
Chain: C: PDB Molecule:dipeptidyl aminopeptidases/acylaminoacyl-peptidases-like
PDBTitle: crystal structure of the sphingopyxin i lasso peptide isopeptidase2 spi-isop (native)
89c2qycA_
not modelled 6.1 8
PDB header:unknown function
Chain: A: PDB Molecule:ferredoxin-like protein;
PDBTitle: crystal structure of a dimeric ferredoxin-like protein (bb1511) from2 bordetella bronchiseptica rb50 at 1.90 a resolution
90c3pg6D_
not modelled 6.1 25
PDB header:ligase
Chain: D: PDB Molecule:e3 ubiquitin-protein ligase dtx3l;
PDBTitle: the carboxyl terminal domain of human deltex 3-like
91c4g6zA_
not modelled 6.1 63
PDB header:ligase
Chain: A: PDB Molecule:glutamate-trna ligase;
PDBTitle: crystal structure of a glutamyl-trna synthetase glurs from2 burkholderia thailandensis bound to l-glutamate
92d1gawa2
not modelled 6.1 7
Fold:Ferredoxin reductase-like, C-terminal NADP-linked domain
Superfamily:Ferredoxin reductase-like, C-terminal NADP-linked domain
Family:Reductases
93c2cfoA_
not modelled 6.1 75
PDB header:ligase
Chain: A: PDB Molecule:glutamyl-trna synthetase;
PDBTitle: non-discriminating glutamyl-trna synthetase from2 thermosynechococcus elongatus in complex with glu
94c4ovqA_
not modelled 6.0 11
PDB header:solute-binding protein
Chain: A: PDB Molecule:trap dicarboxylate abc transporter, substrate-binding
PDBTitle: crystal structure of a trap periplasmic solute binding protein from2 roseobacter denitrificans, target efi-510230, with bound beta-d-3 glucuronate
95d1iwga1
not modelled 6.0 5
Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
96c1g59A_
not modelled 6.0 63
PDB header:ligase/rna
Chain: A: PDB Molecule:glutamyl-trna synthetase;
PDBTitle: glutamyl-trna synthetase complexed with trna(glu).
97c5tcxA_
not modelled 6.0 8
PDB header:cell invasion
Chain: A: PDB Molecule:cd81 antigen;
PDBTitle: crystal structure of human tetraspanin cd81
98c6ithA_
not modelled 5.9 20
PDB header:membrane protein
Chain: A: PDB Molecule:syndecan-2;
PDBTitle: structure of the transmembrane domain of syndecan 2 in micelles
99c2qfiB_
not modelled 5.9 12
PDB header:transport protein
Chain: B: PDB Molecule:ferrous-iron efflux pump fief;
PDBTitle: structure of the zinc transporter yiip

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Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below