1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	E	R	M	R	I	R	A	A	G	I	S	A	T	D	P	H	A	R	L	P	L	P	L	A	R	D	E	I	R	Y	L	G	T	T	F	N	D	L	L	Q	R	L	Q	D	A	L	E	R	E	R	Q	F	V	S	D	A	G	H	E
Secondary structure
SS confidence
Disorder		?											?	?	?	?	?	?			?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.
Sequence		L	R	T	P	L	A	S
Secondary structure
SS confidence
Disorder						?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 27%) Alpha helix ( 73%) Beta strand ( 0%)

Rank Aligned region

PDB 3zrw chain B Region: 1 - 67 Aligned: 67 Modelled: 67 Confidence: 99.7% Identity: 22% PDB header:signaling protein Chain: B: PDB Molecule:af1503 protein, osmolarity sensor protein envz; PDBTitle: the structure of the dimeric hamp-dhp fusion a291v mutant Phyre2 PDB 4biu chain B Region: 1 - 67 Aligned: 61 Modelled: 67 Confidence: 99.2% Identity: 25% PDB header:transferase Chain: B: PDB Molecule:sensor protein cpxa; PDBTitle: crystal structure of cpxahdc (orthorhombic form 1) Phyre2 PDB 4biy chain D Region: 35 - 67 Aligned: 33 Modelled: 33 Confidence: 98.8% Identity: 36% PDB header:transferase Chain: D: PDB Molecule:sensor protein cpxa; PDBTitle: crystal structure of cpxahdc (monoclinic form 2) Phyre2 PDB 3zx6 chain A Region: 1 - 58 Aligned: 58 Modelled: 58 Confidence: 98.8% Identity: 17% PDB header:signaling Chain: A: PDB Molecule:hamp, methyl-accepting chemotaxis protein i; PDBTitle: structure of hamp(af1503)-tsr fusion - hamp (a291v) mutant Phyre2 PDB 3lnr chain A Region: 1 - 64 Aligned: 63 Modelled: 64 Confidence: 98.8% Identity: 11% PDB header:signaling protein Chain: A: PDB Molecule:aerotaxis transducer aer2; PDBTitle: crystal structure of poly-hamp domains from the p. aeruginosa soluble2 receptor aer2 Phyre2 PDB 2asx chain A domain 1 Region: 1 - 48 Aligned: 48 Modelled: 48 Confidence: 98.7% Identity: 25% Fold: HAMP domain-like Superfamily: HAMP domain-like Family: HAMP domain Phyre2 PDB 4gn0 chain D Region: 1 - 52 Aligned: 52 Modelled: 52 Confidence: 98.7% Identity: 23% PDB header:signaling protein Chain: D: PDB Molecule:hamp domain of af1503; PDBTitle: de novo phasing of a hamp-complex using an improved arcimboldo method Phyre2 PDB 4cti chain A Region: 1 - 66 Aligned: 66 Modelled: 66 Confidence: 98.7% Identity: 23% PDB header:signaling protein Chain: A: PDB Molecule:osmolarity sensor protein envz, af1503; PDBTitle: escherichia coli envz histidine kinase catalytic part fused to2 archaeoglobus fulgidus af1503 hamp domain Phyre2 PDB 4mt8 chain A Region: 27 - 67 Aligned: 41 Modelled: 41 Confidence: 98.4% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:ethylene response sensor 1; PDBTitle: structure of the ers1 dimerization and histidine phosphotransfer2 domain from arabidopsis thaliana Phyre2 PDB 5jef chain A Region: 1 - 45 Aligned: 41 Modelled: 45 Confidence: 98.4% Identity: 20% PDB header:transferase Chain: A: PDB Molecule:nitrate/nitrite sensor protein narq; PDBTitle: fragment of nitrate/nitrite sensor histidine kinase narq (wt) in2 asymmetric holo state Phyre2 PDB 5ukv chain A Region: 39 - 67 Aligned: 29 Modelled: 28 Confidence: 98.2% Identity: 48% PDB header:transferase Chain: A: PDB Molecule:atp-binding protein; PDBTitle: dhp domain of phor of m. tuberculosis - semet Phyre2 PDB 1joy chain A Region: 39 - 67 Aligned: 29 Modelled: 29 Confidence: 98.1% Identity: 21% Fold: ROP-like Superfamily: Homodimeric domain of signal transducing histidine kinase Family: Homodimeric domain of signal transducing histidine kinase Phyre2 PDB 4i5s chain A Region: 1 - 52 Aligned: 51 Modelled: 52 Confidence: 98.1% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:putative histidine kinase covs; vick-like protein; PDBTitle: structure and function of sensor histidine kinase Phyre2 PDB 2c2a chain A domain 1 Region: 37 - 67 Aligned: 31 Modelled: 31 Confidence: 97.8% Identity: 35% Fold: ROP-like Superfamily: Homodimeric domain of signal transducing histidine kinase Family: Homodimeric domain of signal transducing histidine kinase Phyre2 PDB 6nb0 chain A Region: 40 - 67 Aligned: 28 Modelled: 28 Confidence: 97.8% Identity: 29% PDB header:transferase Chain: A: PDB Molecule:histidine kinase; PDBTitle: crystal structure of histidine kinase from burkholderia phymatum2 stm815 Phyre2 PDB 2rm8 chain A Region: 11 - 67 Aligned: 56 Modelled: 57 Confidence: 97.7% Identity: 21% PDB header:signaling protein Chain: A: PDB Molecule:sensory rhodopsin ii transducer; PDBTitle: the solution structure of phototactic transducer protein2 htrii linker region from natronomonas pharaonis Phyre2 PDB 4ew8 chain A Region: 35 - 67 Aligned: 33 Modelled: 33 Confidence: 97.6% Identity: 36% PDB header:transferase Chain: A: PDB Molecule:sensor protein divl; PDBTitle: crystal structure of a c-terminal part of tyrosine kinase (divl) from2 caulobacter crescentus cb15 at 2.50 a resolution (psi community3 target, shapiro l.) Phyre2 PDB 2c2a chain A Region: 38 - 67 Aligned: 30 Modelled: 30 Confidence: 97.3% Identity: 37% PDB header:transferase Chain: A: PDB Molecule:sensor histidine kinase; PDBTitle: structure of the entire cytoplasmic portion of a sensor2 histidine kinase protein Phyre2 PDB 5idj chain A Region: 44 - 67 Aligned: 24 Modelled: 24 Confidence: 97.1% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:cell cycle histidine kinase ccka; PDBTitle: bifunctional histidine kinase ccka (domains dhp-ca) in complex with2 adp/mg2+ Phyre2 PDB 4qpk chain A Region: 46 - 67 Aligned: 22 Modelled: 22 Confidence: 96.6% Identity: 23% PDB header:signaling protein Chain: A: PDB Molecule:phosphotransferase; PDBTitle: 1.7 angstrom structure of a bacterial phosphotransferase Phyre2 1 c3zrwB_ 2 c4biuB_ 3 c4biyD_ 4 c3zx6A_ 5 c3lnrA_ 6 d2asxa1 7 c4gn0D_ 8 c4ctiA_ 9 c4mt8A_ 10 c5jefA_ 11 c5ukvA_ 12 d1joya_ 13 c4i5sA_ 14 d2c2aa1 15 c6nb0A_ 16 c2rm8A_ 17 c4ew8A_ 18 c2c2aA_ 19 c5idjA_ 20 c4qpkA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51