1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	G	A	K	H	A	G	R	I	V	A	I	T	T	A	A	A	V	I	L	A	A	C	S	S	G	S	K	G	G	A	G	S	G	H	A	G	K	A	R	S	A	V	T	T	T	D	A	D	W	K	P	V	A	D	A	L	G	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?									?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	G	K	L	G	D	N	N	T	A	Y	R	I	N	L	P	R	N	D	L	H	I	T	S	Y	G	V	D	I	K	P	G	L	S	L	G	G	Y	A	A	F	A	R	Y	D	N	N	E	T	L	L	M	G	D	L	V	I	T	E	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																						?	?	?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		E	L	P	K	V	T	D	A	L	Q	A	H	G	I	A	Q	T	A	L	H	K	H	L	L	Q	Q	D	P	P	V	W	W	T	H	I	H	G	M	G	D	A	A	R	L	A	Q	G	L	K	A	A	L	D	A	T	T	I	G	P	P
Secondary structure
SS confidence
Disorder													?																																											?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	P	P	P	A	R	Q	P	P	V	D	I	D	V	A	G	V	D	Q	A	L	G	R	K	G	T	Q	D	G	G	L	M	K	Y	S	I	P	R	K	D	T	I	I	E	D	G	H	V	L	P	A	V	S	L	N	L	T	T	V	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?								?	?	?	?	?	?													?	?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		N	F	Q	P	V	G	R	G	R	A	A	I	N	G	D	F	I	L	I	A	P	E	V	Q	E	V	I	R	A	M	R	A	G	N	I	T	I	V	E	L	H	N	H	G	L	T	E	E	P	R	L	F	Y	M	H	Y	W	A	V	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.
Sequence		D	A	V	T	L	A	R	A	L	R	P	A	M	D	A	T	N	L	Q	S	S
Secondary structure
SS confidence
Disorder																	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 31%) Alpha helix ( 28%) Beta strand ( 29%)

Rank Aligned region

PDB 6avh chain A Region: 206 - 317 Aligned: 100 Modelled: 112 Confidence: 81.4% Identity: 15% PDB header:ligase, plant protein Chain: A: PDB Molecule:gh3.15 acyl acid amido synthetase; PDBTitle: gh3.15 acyl acid amido synthetase Phyre2 PDB 4ewv chain B Region: 148 - 317 Aligned: 158 Modelled: 170 Confidence: 70.6% Identity: 13% PDB header:ligase Chain: B: PDB Molecule:4-substituted benzoates-glutamate ligase gh3.12; PDBTitle: crystal structure of gh3.12 in complex with ampcpp Phyre2 PDB 2qmw chain A domain 2 Region: 122 - 175 Aligned: 53 Modelled: 54 Confidence: 65.6% Identity: 8% Fold: Ferredoxin-like Superfamily: ACT-like Family: Phenylalanine metabolism regulatory domain Phyre2 PDB 1ddw chain A Region: 282 - 317 Aligned: 36 Modelled: 36 Confidence: 63.4% Identity: 6% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Enabled/VASP homology 1 domain (EVH1 domain) Phyre2 PDB 1xod chain A domain 1 Region: 282 - 314 Aligned: 32 Modelled: 33 Confidence: 61.0% Identity: 22% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Enabled/VASP homology 1 domain (EVH1 domain) Phyre2 PDB 3o1l chain B Region: 263 - 315 Aligned: 52 Modelled: 52 Confidence: 60.6% Identity: 21% PDB header:hydrolase Chain: B: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (pspto_4314)2 from pseudomonas syringae pv. tomato str. dc3000 at 2.20 a resolution Phyre2 PDB 4epl chain A Region: 206 - 315 Aligned: 99 Modelled: 110 Confidence: 58.1% Identity: 15% PDB header:ligase Chain: A: PDB Molecule:jasmonic acid-amido synthetase jar1; PDBTitle: crystal structure of arabidopsis thaliana gh3.11 (jar1) in complex2 with ja-ile Phyre2 PDB 1i7a chain A Region: 282 - 318 Aligned: 37 Modelled: 36 Confidence: 56.3% Identity: 8% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Enabled/VASP homology 1 domain (EVH1 domain) Phyre2 PDB 2mda chain B Region: 122 - 185 Aligned: 58 Modelled: 64 Confidence: 55.6% Identity: 14% PDB header:oxidoreductase Chain: B: PDB Molecule:tyrosine 3-monooxygenase; PDBTitle: the solution structure of the regulatory domain of tyrosine2 hydroxylase Phyre2 PDB 5l0l chain B Region: 286 - 302 Aligned: 17 Modelled: 17 Confidence: 47.8% Identity: 35% PDB header:unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein lpg0439 Phyre2 PDB 2im5 chain C Region: 159 - 215 Aligned: 55 Modelled: 57 Confidence: 47.4% Identity: 15% PDB header:transferase Chain: C: PDB Molecule:nicotinate phosphoribosyltransferase; PDBTitle: crystal structure of nicotinate phosphoribosyltransferase from2 porphyromonas gingivalis Phyre2 PDB 3do6 chain B Region: 259 - 319 Aligned: 49 Modelled: 61 Confidence: 41.9% Identity: 14% PDB header:ligase Chain: B: PDB Molecule:formate--tetrahydrofolate ligase; PDBTitle: crystal structure of putative formyltetrahydrofolate synthetase2 (tm1766) from thermotoga maritima at 1.85 a resolution Phyre2 PDB 1evh chain A Region: 283 - 314 Aligned: 32 Modelled: 32 Confidence: 41.8% Identity: 19% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Enabled/VASP homology 1 domain (EVH1 domain) Phyre2 PDB 1zhv chain A Region: 115 - 142 Aligned: 28 Modelled: 28 Confidence: 40.6% Identity: 29% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein atu0741; PDBTitle: x-ray crystal structure protein atu0741 from agobacterium tumefaciens.2 northeast structural genomics consortium target atr8. Phyre2 PDB 2dfa chain A domain 1 Region: 257 - 319 Aligned: 59 Modelled: 63 Confidence: 39.3% Identity: 20% Fold: 7-stranded beta/alpha barrel Superfamily: Glycoside hydrolase/deacetylase Family: LamB/YcsF-like Phyre2 PDB 4j38 chain A Region: 256 - 274 Aligned: 19 Modelled: 19 Confidence: 36.8% Identity: 26% PDB header:immune system Chain: A: PDB Molecule:outer surface protein e; PDBTitle: structure of borrelia burgdorferi outer surface protein e in complex2 with factor h domains 19-20 Phyre2 PDB 1nh8 chain A domain 2 Region: 107 - 141 Aligned: 35 Modelled: 35 Confidence: 34.4% Identity: 11% Fold: Ferredoxin-like Superfamily: GlnB-like Family: ATP phosphoribosyltransferase (ATP-PRTase, HisG), regulatory C-terminal domain Phyre2 PDB 2ivf chain B Region: 107 - 153 Aligned: 42 Modelled: 47 Confidence: 33.9% Identity: 17% PDB header:oxidoreductase Chain: B: PDB Molecule:ethylbenzene dehydrogenase beta-subunit; PDBTitle: ethylbenzene dehydrogenase from aromatoleum aromaticum Phyre2 PDB 1qc6 chain A Region: 283 - 317 Aligned: 35 Modelled: 35 Confidence: 33.0% Identity: 17% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Enabled/VASP homology 1 domain (EVH1 domain) Phyre2 PDB 1pdo chain A Region: 282 - 317 Aligned: 36 Modelled: 36 Confidence: 32.3% Identity: 14% Fold: PTS system fructose IIA component-like Superfamily: PTS system fructose IIA component-like Family: EIIA-man component-like Phyre2 1 c6avhA_ 2 c4ewvB_ 3 d2qmwa2 4 d1ddwa_ 5 d1xoda1 6 c3o1lB_ 7 c4eplA_ 8 d1i7aa_ 9 c2mdaB_ 10 c5l0lB_ 11 c2im5C_ 12 c3do6B_ 13 d1evha_ 14 c1zhvA_ 15 d2dfaa1 16 c4j38A_ 17 d1nh8a2 18 c2ivfB_ 19 d1qc6a_ 20 d1pdoa_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99