1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	S	E	D	V	A	R	I	H	D	G	D	V	I	D	E	S	F	D	E	L	M	G	M	L	D	H	P	V	F	V	V	T	T	Q	A	D	G	H	P	A	G	C	L	V	S	F	A	T	Q	T	S	V	Q	P	P	S	F	M	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	L	P	R	S	T	G	T	S	E	V	A	S	R	S	E	H	L	A	V	H	V	L	S	Q	R	Q	H	V	L	A	E	L	F	G	S	Q	T	E	E	E	V	N	K	F	A	R	C	S	W	R	A	G	P	C	G	M	P	I	L
Secondary structure
SS confidence
Disorder																																					?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		D	D	A	A	A	W	F	I	G	R	T	A	S	R	S	D	V	G	D	Y	V	A	Y	L	L	E	P	V	S	V	W	A	P	E	C	S	E	D	L	L	Y	L	S	D	L	D	F	D	V	D	D	I	D	P	G	K	E	A	S	P
Secondary structure
SS confidence
Disorder																																	?																?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.
Sequence		R	F	Y	E	R	E	R	G	D	E	T	R	R	Y	G	V	V	R	F	T	L	D	V	P
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?													?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 24%) Alpha helix ( 13%) Beta strand ( 41%)

Rank Aligned region

PDB 3rh7 chain A Region: 6 - 168 Aligned: 159 Modelled: 163 Confidence: 100.0% Identity: 26% PDB header:oxidoreductase Chain: A: PDB Molecule:hypothetical oxidoreductase; PDBTitle: crystal structure of a putative oxidoreductase (sma0793) from2 sinorhizobium meliloti 1021 at 3.00 a resolution Phyre2 PDB 5zc2 chain B Region: 13 - 185 Aligned: 168 Modelled: 173 Confidence: 100.0% Identity: 19% PDB header:flavoprotein Chain: B: PDB Molecule:p-hydroxyphenylacetate 3-hydroxylase, reductase component; PDBTitle: acinetobacter baumannii p-hydroxyphenylacetate 3-hydroxylase (hpah),2 reductase component (c1) Phyre2 PDB 4hx6 chain D Region: 2 - 171 Aligned: 169 Modelled: 170 Confidence: 100.0% Identity: 19% PDB header:oxidoreductase Chain: D: PDB Molecule:oxidoreductase; PDBTitle: streptomyces globisporus c-1027 nadh:fad oxidoreductase sgce6 Phyre2 PDB 3nfw chain B Region: 10 - 189 Aligned: 174 Modelled: 180 Confidence: 100.0% Identity: 18% PDB header:oxidoreductase Chain: B: PDB Molecule:flavin reductase-like, fmn-binding protein; PDBTitle: crystal structure of nitrilotriacetate monooxygenase component b2 (a0r521 homolog) from mycobacterium thermoresistibile Phyre2 PDB 2qck chain A Region: 14 - 175 Aligned: 158 Modelled: 162 Confidence: 100.0% Identity: 27% PDB header:oxidoreductase Chain: A: PDB Molecule:flavin reductase domain protein; PDBTitle: crystal structure of flavin reductase domain protein (yp_831077.1)2 from arthrobacter sp. fb24 at 1.90 a resolution Phyre2 PDB 3k87 chain B Region: 12 - 172 Aligned: 161 Modelled: 161 Confidence: 100.0% Identity: 24% PDB header:oxidoreductase Chain: B: PDB Molecule:chlorophenol-4-monooxygenase component 1; PDBTitle: crystal structure of nadh:fad oxidoreductase (tftc) - fad2 complex Phyre2 PDB 3pft chain A Region: 12 - 170 Aligned: 156 Modelled: 159 Confidence: 100.0% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:flavin reductase; PDBTitle: crystal structure of untagged c54a mutant flavin reductase (dszd) in2 complex with fmn from mycobacterium goodii Phyre2 PDB 1wgb chain A Region: 16 - 168 Aligned: 153 Modelled: 153 Confidence: 100.0% Identity: 23% Fold: Split barrel-like Superfamily: FMN-binding split barrel Family: NADH:FMN oxidoreductase-like Phyre2 PDB 2r0x chain A Region: 13 - 169 Aligned: 156 Modelled: 157 Confidence: 100.0% Identity: 22% PDB header:oxidoreductase Chain: A: PDB Molecule:possible flavin reductase; PDBTitle: crystal structure of a putative flavin reductase (ycdh, hs_1225) from2 haemophilus somnus 129pt at 1.06 a resolution Phyre2 PDB 3cb0 chain B Region: 11 - 169 Aligned: 159 Modelled: 159 Confidence: 100.0% Identity: 21% PDB header:oxidoreductase Chain: B: PDB Molecule:4-hydroxyphenylacetate 3-monooxygenase; PDBTitle: cobr Phyre2 PDB 4l82 chain D Region: 13 - 169 Aligned: 154 Modelled: 157 Confidence: 100.0% Identity: 21% PDB header:oxidoreductase Chain: D: PDB Molecule:rifea.00250.a; PDBTitle: structure of a putative oxidoreductase from rickettsia felis Phyre2 PDB 2d38 chain A Region: 14 - 172 Aligned: 155 Modelled: 159 Confidence: 100.0% Identity: 20% PDB header:oxidoreductase Chain: A: PDB Molecule:hypothetical nadh-dependent fmn oxidoreductase; PDBTitle: the crystal structure of flavin reductase hpac complexed with nadp+ Phyre2 PDB 4xhy chain A Region: 12 - 171 Aligned: 156 Modelled: 156 Confidence: 100.0% Identity: 20% PDB header:oxidoreductase Chain: A: PDB Molecule:flavin reductase domain protein, fmn-binding protein; PDBTitle: nadh:fmn oxidoreductase from paracoccus denitrificans Phyre2 PDB 2ecr chain A Region: 14 - 170 Aligned: 146 Modelled: 154 Confidence: 100.0% Identity: 18% PDB header:oxidoreductase Chain: A: PDB Molecule:flavin reductase component (hpac) of 4-hydroxyphenylacetate PDBTitle: crystal structure of the ligand-free form of the flavin reductase2 component (hpac) of 4-hydroxyphenylacetate 3-monooxygenase Phyre2 PDB 1i0r chain A Region: 19 - 178 Aligned: 157 Modelled: 160 Confidence: 100.0% Identity: 21% Fold: Split barrel-like Superfamily: FMN-binding split barrel Family: NADH:FMN oxidoreductase-like Phyre2 PDB 4f07 chain A Region: 17 - 172 Aligned: 149 Modelled: 156 Confidence: 100.0% Identity: 21% PDB header:oxidoreductase Chain: A: PDB Molecule:styrene monooxygenase component 2; PDBTitle: structure of the styrene monooxygenase flavin reductase (smob) from2 pseudomonas putida s12 Phyre2 PDB 1rz0 chain A Region: 14 - 171 Aligned: 152 Modelled: 151 Confidence: 100.0% Identity: 25% Fold: Split barrel-like Superfamily: FMN-binding split barrel Family: NADH:FMN oxidoreductase-like Phyre2 PDB 3bnk chain B Region: 22 - 172 Aligned: 151 Modelled: 151 Confidence: 100.0% Identity: 16% PDB header:electron transport Chain: B: PDB Molecule:flavoredoxin; PDBTitle: x-ray crystal structure of flavoredoxin from methanosarcina2 acetivorans Phyre2 PDB 1usc chain A Region: 22 - 177 Aligned: 155 Modelled: 156 Confidence: 100.0% Identity: 21% Fold: Split barrel-like Superfamily: FMN-binding split barrel Family: NADH:FMN oxidoreductase-like Phyre2 PDB 2r6v chain A Region: 25 - 178 Aligned: 154 Modelled: 154 Confidence: 100.0% Identity: 14% PDB header:flavoprotein Chain: A: PDB Molecule:uncharacterized protein ph0856; PDBTitle: crystal structure of fmn-binding protein (np_142786.1) from pyrococcus2 horikoshii at 1.35 a resolution Phyre2 1 c3rh7A_ 2 c5zc2B_ 3 c4hx6D_ 4 c3nfwB_ 5 c2qckA_ 6 c3k87B_ 7 c3pftA_ 8 d1wgba_ 9 c2r0xA_ 10 c3cb0B_ 11 c4l82D_ 12 c2d38A_ 13 c4xhyA_ 14 c2ecrA_ 15 d1i0ra_ 16 c4f07A_ 17 d1rz0a_ 18 c3bnkB_ 19 d1usca_ 20 c2r6vA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99