1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	V	G	L	T	R	P	L	L	L	C	G	A	T	L	L	I	A	A	C	T	R	V	V	G	G	T	A	S	A	T	F	G	G	D	R	Q	G	M	L	D	V	A	T	I	L	L	D	Q	S	R	M	Q	A	I	T	G	S	G	D
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?											?		?	?	?	?	?		?	?	?	?	?	?	?	?	?	?	?	?					?				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	L	T	I	I	P	T	M	D	T	T	Y	P	V	D	V	D	D	F	A	Q	P	I	P	R	E	C	R	F	I	Y	A	E	T	A	V	F	G	S	E	I	E	A	F	H	K	T	T	F	Q	D	R	P	D	G	S	L	I	S	E
Secondary structure
SS confidence
Disorder										?	?							?	?	?	?	?	?																								?	?	?	?	?	?	?	?	?			?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	A	A	A	Y	R	D	A	G	T	A	R	R	A	F	D	T	L	A	V	T	V	H	D	C	A	A	S	P	A	G	W	L	F	V	S	R	W	T	A	G	G	N	S	L	H	I	R	A	G	D	C	G	R	D	Y	R	V	L	S
Secondary structure
SS confidence
Disorder			?	?	?	?	?	?																																				?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.
Sequence		A	A	L	L	E	V	T	F	C	G	F	P	E	S	V	S	D	I	V	M	T	N	I	A	A	N	V	P	G
Secondary structure
SS confidence
Disorder																											?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 28%) Alpha helix ( 49%) Beta strand ( 14%)

Rank Aligned region

PDB 4esq chain A Region: 33 - 209 Aligned: 172 Modelled: 177 Confidence: 100.0% Identity: 19% PDB header:transferase Chain: A: PDB Molecule:serine/threonine protein kinase; PDBTitle: crystal structure of the extracellular domain of pknh from2 mycobacterium tuberculosis Phyre2 PDB 4ash chain B Region: 146 - 186 Aligned: 41 Modelled: 41 Confidence: 48.6% Identity: 27% PDB header:hydrolase Chain: B: PDB Molecule:ns6 protease; PDBTitle: crystal structure of the ns6 protease from murine norovirus 1 Phyre2 PDB 3lo3 chain E Region: 121 - 139 Aligned: 19 Modelled: 19 Confidence: 22.6% Identity: 5% PDB header:structure genomics, unknown function Chain: E: PDB Molecule:uncharacterized conserved protein; PDBTitle: the crystal structure of a conserved functionally unknown protein from2 colwellia psychrerythraea 34h. Phyre2 PDB 1pft chain A Region: 84 - 104 Aligned: 21 Modelled: 21 Confidence: 15.4% Identity: 29% Fold: Rubredoxin-like Superfamily: Zinc beta-ribbon Family: Transcriptional factor domain Phyre2 PDB 2fiu chain A domain 1 Region: 121 - 139 Aligned: 19 Modelled: 19 Confidence: 15.0% Identity: 5% Fold: Ferredoxin-like Superfamily: Dimeric alpha+beta barrel Family: Atu0297-like Phyre2 PDB 1dl6 chain A Region: 84 - 104 Aligned: 21 Modelled: 21 Confidence: 13.9% Identity: 29% Fold: Rubredoxin-like Superfamily: Zinc beta-ribbon Family: Transcriptional factor domain Phyre2 PDB 3k1f chain M Region: 84 - 104 Aligned: 21 Modelled: 21 Confidence: 13.3% Identity: 24% PDB header:transcription Chain: M: PDB Molecule:transcription initiation factor iib; PDBTitle: crystal structure of rna polymerase ii in complex with tfiib Phyre2 PDB 5a6w chain C Region: 172 - 189 Aligned: 17 Modelled: 18 Confidence: 12.9% Identity: 12% PDB header:antiviral protein Chain: C: PDB Molecule:avr-pik protein; PDBTitle: complex of rice blast (magnaporthe oryzae) effector protein avr-pikd2 with the hma domain of pikp1 from rice (oryza sativa) Phyre2 PDB 2js3 chain B Region: 192 - 208 Aligned: 17 Modelled: 17 Confidence: 12.2% Identity: 12% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: nmr structure of protein q6n9a4_rhopa. northeast structural genomics2 consortium target rpt8 Phyre2 PDB 4wj2 chain A Region: 21 - 60 Aligned: 40 Modelled: 40 Confidence: 12.0% Identity: 20% PDB header:unknown function Chain: A: PDB Molecule:antigen mtb48; PDBTitle: mycobacterial protein Phyre2 PDB 4i0x chain A Region: 97 - 106 Aligned: 10 Modelled: 10 Confidence: 10.5% Identity: 10% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:esat-6-like protein mab_3112; PDBTitle: crystal structure of the mycobacterum abscessus esxef (mab_3112-2 mab_3113) complex Phyre2 PDB 3dca chain C Region: 107 - 139 Aligned: 33 Modelled: 31 Confidence: 10.1% Identity: 9% PDB header:structural genomics, unknown function Chain: C: PDB Molecule:rpa0582; PDBTitle: crystal structure of the rpa0582- protein of unknown2 function from rhodopseudomonas palustris- a structural3 genomics target Phyre2 PDB 2b3g chain B Region: 32 - 53 Aligned: 19 Modelled: 22 Confidence: 9.4% Identity: 11% PDB header:replication Chain: B: PDB Molecule:cellular tumor antigen p53; PDBTitle: p53n (fragment 33-60) bound to rpa70n Phyre2 PDB 4zjf chain A Region: 166 - 193 Aligned: 28 Modelled: 28 Confidence: 8.2% Identity: 18% PDB header:viral protein Chain: A: PDB Molecule:glycoprotein; PDBTitle: crystal structure of gp1 - the receptor binding domain of lassa virus Phyre2 PDB 3i08 chain D Region: 125 - 141 Aligned: 17 Modelled: 17 Confidence: 7.8% Identity: 18% PDB header:signaling protein Chain: D: PDB Molecule:neurogenic locus notch homolog protein 1; PDBTitle: crystal structure of the s1-cleaved notch1 negative2 regulatory region (nrr) Phyre2 PDB 1hsk chain A Region: 155 - 206 Aligned: 52 Modelled: 52 Confidence: 6.6% Identity: 19% PDB header:oxidoreductase Chain: A: PDB Molecule:udp-n-acetylenolpyruvoylglucosamine reductase; PDBTitle: crystal structure of s. aureus murb Phyre2 PDB 1zzp chain A Region: 22 - 56 Aligned: 31 Modelled: 35 Confidence: 5.3% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1; PDBTitle: solution structure of the f-actin binding domain of bcr-2 abl/c-abl Phyre2 PDB 2h8b chain A Region: 12 - 23 Aligned: 12 Modelled: 12 Confidence: 5.0% Identity: 17% PDB header:hormone/growth factor Chain: A: PDB Molecule:insulin-like 3; PDBTitle: solution structure of insl3 Phyre2 PDB 2k6t chain A Region: 12 - 23 Aligned: 12 Modelled: 12 Confidence: 5.0% Identity: 17% PDB header:hormone Chain: A: PDB Molecule:insulin-like 3 a chain; PDBTitle: solution structure of the relaxin-like factor Phyre2 1 c4esqA_ 2 c4ashB_ 3 c3lo3E_ 4 d1pfta_ 5 d2fiua1 6 d1dl6a_ 7 c3k1fM_ 8 c5a6wC_ 9 c2js3B_ 10 c4wj2A_ 11 c4i0xA_ 12 c3dcaC_ 13 c2b3gB_ 14 c4zjfA_ 15 c3i08D_ 16 c1hskA_ 17 c1zzpA_ 18 c2h8bA_ 19 c2k6tA_