1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	S	Q	S	M	Y	S	Y	P	A	M	T	A	N	V	G	D	M	A	G	Y	T	G	T	T	Q	S	L	G	A	D	I	A	S	E	R	T	A	P	S	R	A	C	Q	G	D	L	G	M	S	H	Q	D	W	Q	A	Q	W	N	Q
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																					?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	M	E	A	L	A	R	A	Y	R	R	C	R	R	A	L	R	Q	I	G	V	L	E	R	P	V	G	D	S	S	D	C	G	T	I	R	V	G	S	F	R	G	R	W	L	D	P	R	H	A	G	P	A	T	A	A	D	A	G	D
Secondary structure
SS confidence
Disorder																								?																											?		?	?	?	?	?	?	?	?	?
Disorder confidence
Sequence
Secondary structure
SS confidence
Disorder
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 29%) Alpha helix ( 62%) Beta strand ( 6%)

Rank Aligned region

PDB 3q4h chain B Region: 7 - 70 Aligned: 64 Modelled: 64 Confidence: 100.0% Identity: 52% PDB header:metal transport Chain: B: PDB Molecule:low molecular weight protein antigen 7; PDBTitle: crystal structure of the mycobacterium smegmatis esxgh complex2 (msmeg_0620-msmeg_0621) Phyre2 PDB 3h6p chain D Region: 20 - 70 Aligned: 51 Modelled: 51 Confidence: 100.0% Identity: 65% PDB header:structural genomics, unknown function Chain: D: PDB Molecule:esat-6-like protein esxr; PDBTitle: crystal structure of rv3019c-rv3020c from mycobacterium tuberculosis Phyre2 PDB 2kg7 chain B Region: 1 - 80 Aligned: 80 Modelled: 80 Confidence: 98.6% Identity: 56% PDB header:unknown function Chain: B: PDB Molecule:esat-6-like protein esxh; PDBTitle: structure and features of the complex formed by the tuberculosis2 virulence factors rv0287 and rv0288 Phyre2 PDB 1wa8 chain B domain 1 Region: 2 - 80 Aligned: 79 Modelled: 79 Confidence: 98.4% Identity: 18% Fold: Ferritin-like Superfamily: EsxAB dimer-like Family: ESAT-6 like Phyre2 PDB 4lws chain B Region: 3 - 80 Aligned: 78 Modelled: 78 Confidence: 97.5% Identity: 12% PDB header:unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: esxa : esxb (semet) hetero-dimer from thermomonospora curvata Phyre2 PDB 4lws chain A Region: 3 - 80 Aligned: 78 Modelled: 78 Confidence: 97.1% Identity: 15% PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: esxa : esxb (semet) hetero-dimer from thermomonospora curvata Phyre2 PDB 1wa8 chain A domain 1 Region: 2 - 80 Aligned: 79 Modelled: 79 Confidence: 95.6% Identity: 13% Fold: Ferritin-like Superfamily: EsxAB dimer-like Family: ESAT-6 like Phyre2 PDB 3gvm chain A Region: 1 - 79 Aligned: 79 Modelled: 79 Confidence: 95.4% Identity: 9% PDB header:viral protein Chain: A: PDB Molecule:putative uncharacterized protein sag1039; PDBTitle: structure of the homodimeric wxg-100 family protein from streptococcus2 agalactiae Phyre2 PDB 4iog chain D Region: 1 - 79 Aligned: 79 Modelled: 79 Confidence: 94.5% Identity: 14% PDB header:unknown function Chain: D: PDB Molecule:secreted protein esxb; PDBTitle: the crystal structure of a secreted protein esxb (wild-type, in p212 space group) from bacillus anthracis str. sterne Phyre2 PDB 3zbh chain C Region: 11 - 79 Aligned: 69 Modelled: 69 Confidence: 90.4% Identity: 9% PDB header:unknown function Chain: C: PDB Molecule:esxa; PDBTitle: geobacillus thermodenitrificans esxa crystal form i Phyre2 PDB 2vs0 chain B Region: 4 - 79 Aligned: 76 Modelled: 76 Confidence: 90.0% Identity: 11% PDB header:cell invasion Chain: B: PDB Molecule:virulence factor esxa; PDBTitle: structural analysis of homodimeric staphylococcal aureus2 virulence factor esxa Phyre2 PDB 2do5 chain A Region: 51 - 90 Aligned: 40 Modelled: 40 Confidence: 29.6% Identity: 45% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:splicing factor 3b subunit 2; PDBTitle: solution structure of the sap domain of human splicing2 factor 3b subunit 2 Phyre2 PDB 1ju8 chain A Region: 82 - 107 Aligned: 26 Modelled: 26 Confidence: 26.3% Identity: 35% Fold: Knottins (small inhibitors, toxins, lectins) Superfamily: omega toxin-like Family: Albumin 1 Phyre2 PDB 3wof chain B Region: 42 - 51 Aligned: 10 Modelled: 10 Confidence: 25.9% Identity: 60% PDB header:transferase/transcription Chain: B: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of p23-45 gp39 (6-132) bound to thermus thermophilus2 rna polymerase beta-flap domain Phyre2 PDB 3wod chain G Region: 42 - 51 Aligned: 10 Modelled: 10 Confidence: 23.2% Identity: 60% PDB header:transferase/transcription Chain: G: PDB Molecule:putative uncharacterized protein; PDBTitle: rna polymerase-gp39 complex Phyre2 PDB 5tc1 chain M Region: 64 - 106 Aligned: 35 Modelled: 43 Confidence: 21.4% Identity: 46% PDB header:viral protein/rna Chain: M: PDB Molecule:maturation protein; PDBTitle: in situ structures of the genome and genome-delivery apparatus in2 ssrna bacteriophage ms2 Phyre2 PDB 3qbz chain A Region: 51 - 62 Aligned: 12 Modelled: 12 Confidence: 21.2% Identity: 33% PDB header:cell cycle Chain: A: PDB Molecule:ddk kinase regulatory subunit dbf4; PDBTitle: crystal structure of the rad53-recognition domain of saccharomyces2 cerevisiae dbf4 Phyre2 PDB 5t2s chain A Region: 47 - 62 Aligned: 16 Modelled: 16 Confidence: 20.0% Identity: 25% PDB header:cell cycle Chain: A: PDB Molecule:ddk kinase regulatory subunit dbf4,serine/threonine-protein PDBTitle: structure of the fha1 domain of rad53 bound simultaneously to the brct2 domain of dbf4 and a phosphopeptide. Phyre2 PDB 1p8b chain A Region: 82 - 107 Aligned: 26 Modelled: 26 Confidence: 19.8% Identity: 35% Fold: Knottins (small inhibitors, toxins, lectins) Superfamily: omega toxin-like Family: Albumin 1 Phyre2 PDB 3cr3 chain A domain 1 Region: 59 - 94 Aligned: 35 Modelled: 36 Confidence: 19.6% Identity: 23% Fold: DhaL-like Superfamily: DhaL-like Family: DhaL-like Phyre2 1 c3q4hB_ 2 c3h6pD_ 3 c2kg7B_ 4 d1wa8b1 5 c4lwsB_ 6 c4lwsA_ 7 d1wa8a1 8 c3gvmA_ 9 c4iogD_ 10 c3zbhC_ 11 c2vs0B_ 12 c2do5A_ 13 d1ju8a_ 14 c3wofB_ 15 c3wodG_ 16 c5tc1M_ 17 c3qbzA_ 18 c5t2sA_ 19 d1p8ba_ 20 d3cr3a1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72