1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	I	A	S	V	L	I	P	S	D	K	P	H	G	V	A	T	G	S	S	T	G	P	R	Y	S	L	L	L	S	T	D	P	S	M	V	E	A	A	Q	R	L	R	Y	D	V	F	S	T	T	P	G	F	A	L	P	A	A	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																																		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	T	R	R	D	G	D	R	F	D	E	Y	C	D	H	L	L	V	R	D	D	D	T	G	E	L	V	G	C	Y	R	M	L	A	P	A	G	A	I	A	A	G	G	L	Y	T	A	T	E	F	D	V	C	A	F	D	P	L	R	P
Secondary structure
SS confidence
Disorder		?																																			?	?	?			?			?										?		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		S	L	V	E	M	G	R	A	V	V	R	E	G	H	R	N	G	G	V	V	L	L	M	W	A	G	I	L	A	Y	L	D	R	Y	G	Y	D	Y	V	T	G	C	V	S	V	P	I	G	G	D	G	E	T	P	G	S	R	L	R	G
Secondary structure
SS confidence
Disorder														?																																				?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		V	R	D	F	I	L	N	R	H	A	A	P	P	Q	C	Q	V	Y	P	Y	R	P	V	R	V	D	G	R	S	L	D	D	I	L	P	P	P	R	P	A	V	P	P	L	M	R	G	Y	L	R	L	G	A	R	A	C	G	E	P	A
Secondary structure
SS confidence
Disorder																										?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.
Sequence		H	D	P	D	F	G	V	G	D	F	C	L	L	L	D	K	D	H	A	D	T	R	Y	L	R	R	L	R	S	V	A	A	A	S	E	M	V	N	D	A	R
Secondary structure
SS confidence
Disorder																																							?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 21%) Alpha helix ( 39%) Beta strand ( 19%)

Rank Aligned region

PDB 5w8c chain A Region: 31 - 164 Aligned: 130 Modelled: 134 Confidence: 100.0% Identity: 18% PDB header:biosynthetic protein Chain: A: PDB Molecule:autoinducer synthase; PDBTitle: the structure of a coa-dependent acyl-homoserine lactone synthase,2 bjai, with mta and isovaleryl-coa Phyre2 PDB 1ro5 chain A Region: 23 - 164 Aligned: 137 Modelled: 142 Confidence: 100.0% Identity: 18% Fold: Acyl-CoA N-acyltransferases (Nat) Superfamily: Acyl-CoA N-acyltransferases (Nat) Family: Autoinducer synthetase Phyre2 PDB 3p2f chain A Region: 33 - 164 Aligned: 114 Modelled: 132 Confidence: 99.9% Identity: 20% PDB header:signaling protein Chain: A: PDB Molecule:ahl synthase; PDBTitle: crystal structure of tofi in an apo form Phyre2 PDB 1kzf chain A Region: 41 - 164 Aligned: 117 Modelled: 124 Confidence: 99.9% Identity: 16% Fold: Acyl-CoA N-acyltransferases (Nat) Superfamily: Acyl-CoA N-acyltransferases (Nat) Family: Autoinducer synthetase Phyre2 PDB 2g0b chain G Region: 33 - 262 Aligned: 162 Modelled: 171 Confidence: 99.8% Identity: 20% PDB header:transferase Chain: G: PDB Molecule:feem; PDBTitle: the structure of feem, an n-acyl amino acid synthase from uncultured2 soil microbes Phyre2 PDB 1q2y chain A Region: 27 - 167 Aligned: 109 Modelled: 109 Confidence: 99.6% Identity: 19% Fold: Acyl-CoA N-acyltransferases (Nat) Superfamily: Acyl-CoA N-acyltransferases (Nat) Family: N-acetyl transferase, NAT Phyre2 PDB 3efa chain A Region: 25 - 164 Aligned: 111 Modelled: 115 Confidence: 99.5% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:putative acetyltransferase; PDBTitle: crystal structure of putative n-acetyltransferase from lactobacillus2 plantarum Phyre2 PDB 1xeb chain A Region: 33 - 164 Aligned: 104 Modelled: 111 Confidence: 99.2% Identity: 21% Fold: Acyl-CoA N-acyltransferases (Nat) Superfamily: Acyl-CoA N-acyltransferases (Nat) Family: N-acetyl transferase, NAT Phyre2 PDB 5z6n chain A Region: 33 - 167 Aligned: 104 Modelled: 104 Confidence: 99.1% Identity: 25% PDB header:transferase Chain: A: PDB Molecule:protein elaa; PDBTitle: crystal structure of escherichia coli elaa Phyre2 PDB 2jdc chain A domain 1 Region: 27 - 160 Aligned: 105 Modelled: 115 Confidence: 98.8% Identity: 12% Fold: Acyl-CoA N-acyltransferases (Nat) Superfamily: Acyl-CoA N-acyltransferases (Nat) Family: N-acetyl transferase, NAT Phyre2 PDB 3lod chain A Region: 26 - 164 Aligned: 104 Modelled: 116 Confidence: 98.2% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:putative acyl-coa n-acyltransferase; PDBTitle: the crystal structure of the putative acyl-coa n-acyltransferase from2 klebsiella pneumoniae subsp.pneumoniae mgh 78578 Phyre2 PDB 2q7b chain A Region: 26 - 164 Aligned: 116 Modelled: 115 Confidence: 98.2% Identity: 8% PDB header:transferase Chain: A: PDB Molecule:acetyltransferase, gnat family; PDBTitle: crystal structure of acetyltransferase (np_689019.1) from2 streptococcus agalactiae 2603 at 2.00 a resolution Phyre2 PDB 3d8p chain B Region: 33 - 164 Aligned: 109 Modelled: 109 Confidence: 98.2% Identity: 11% PDB header:transferase Chain: B: PDB Molecule:acetyltransferase of gnat family; PDBTitle: crystal structure of acetyltransferase of gnat family (np_373092.1)2 from staphylococcus aureus mu50 at 2.20 a resolution Phyre2 PDB 2r98 chain A Region: 14 - 160 Aligned: 115 Modelled: 125 Confidence: 98.1% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:putative acetylglutamate synthase; PDBTitle: crystal structure of n-acetylglutamate synthase (selenomet2 substituted) from neisseria gonorrhoeae Phyre2 PDB 1z4r chain A domain 1 Region: 24 - 164 Aligned: 111 Modelled: 117 Confidence: 98.1% Identity: 22% Fold: Acyl-CoA N-acyltransferases (Nat) Superfamily: Acyl-CoA N-acyltransferases (Nat) Family: N-acetyl transferase, NAT Phyre2 PDB 2ree chain B Region: 26 - 237 Aligned: 170 Modelled: 179 Confidence: 98.0% Identity: 16% PDB header:transferase, lyase Chain: B: PDB Molecule:cura; PDBTitle: crystal structure of the loading gnatl domain of cura from lyngbya2 majuscula Phyre2 PDB 1qsr chain A Region: 28 - 164 Aligned: 107 Modelled: 113 Confidence: 98.0% Identity: 17% Fold: Acyl-CoA N-acyltransferases (Nat) Superfamily: Acyl-CoA N-acyltransferases (Nat) Family: N-acetyl transferase, NAT Phyre2 PDB 1ib1 chain E Region: 10 - 164 Aligned: 142 Modelled: 153 Confidence: 98.0% Identity: 13% PDB header:signaling protein/transferase Chain: E: PDB Molecule:serotonin n-acetyltransferase; PDBTitle: crystal structure of the 14-3-3 zeta:serotonin n-acetyltransferase2 complex Phyre2 PDB 3mgd chain B Region: 33 - 160 Aligned: 112 Modelled: 112 Confidence: 98.0% Identity: 5% PDB header:transferase Chain: B: PDB Molecule:predicted acetyltransferase; PDBTitle: crystal structure of predicted acetyltransferase with acetyl-coa from2 clostridium acetobutylicum at the resolution 1.9a, northeast3 structural genomics consortium target car165 Phyre2 PDB 3sxn chain C Region: 24 - 160 Aligned: 115 Modelled: 122 Confidence: 97.9% Identity: 18% PDB header:transferase Chain: C: PDB Molecule:enhanced intracellular survival protein; PDBTitle: mycobacterium tuberculosis eis protein initiates modulation of host2 immune responses by acetylation of dusp16/mkp-7 Phyre2 1 c5w8cA_ 2 d1ro5a_ 3 c3p2fA_ 4 d1kzfa_ 5 c2g0bG_ 6 d1q2ya_ 7 c3efaA_ 8 d1xeba_ 9 c5z6nA_ 10 d2jdca1 11 c3lodA_ 12 c2q7bA_ 13 c3d8pB_ 14 c2r98A_ 15 d1z4ra1 16 c2reeB_ 17 d1qsra_ 18 c1ib1E_ 19 c3mgdB_ 20 c3sxnC_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229