1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	K	P	Q	D	Q	G	L	H	F	P	Y	R	Y	D	L	R	L	A	P	M	W	L	P	F	R	W	P	G	S	Q	G	V	T	V	T	E	D	G	R	F	V	A	R	Y	G	P	F	R	V	E	A	P	L	S	S	V	R	D	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																																		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		H	I	T	G	P	Y	R	W	W	T	A	V	G	P	R	L	S	M	V	D	D	G	L	T	F	G	T	N	A	A	A	G	V	C	I	H	F	E	P	R	I	H	R	V	I	G	L	R	D	H	S	A	L	T	V	T	V	A	D	P
Secondary structure
SS confidence
Disorder																										?															?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.
Sequence		E	G	L	V	A	A	L	S	S
Secondary structure
SS confidence
Disorder									?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 17%) Alpha helix ( 9%) Beta strand ( 46%)

Rank Aligned region

PDB 1wj9 chain A domain 2 Region: 114 - 129 Aligned: 16 Modelled: 16 Confidence: 24.1% Identity: 38% Fold: Ferredoxin-like Superfamily: CRISPR-associated protein Family: CRISPR-associated protein Phyre2 PDB 4dzd chain A Region: 114 - 128 Aligned: 15 Modelled: 15 Confidence: 15.3% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized protein ygch; PDBTitle: crystal structure of the crispr-associated protein cas6e from2 escherichia coli str. k-12 Phyre2 PDB 4ld7 chain N Region: 67 - 111 Aligned: 45 Modelled: 45 Confidence: 13.3% Identity: 22% PDB header:transferase Chain: N: PDB Molecule:dimethylallyl tryptophan synthase; PDBTitle: crystal structure of anapt from neosartorya fischeri Phyre2 PDB 4whi chain A Region: 27 - 100 Aligned: 66 Modelled: 74 Confidence: 12.5% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of c-terminal domain of penicillin binding protein2 rv0907 Phyre2 PDB 3qrq chain A Region: 114 - 127 Aligned: 14 Modelled: 14 Confidence: 12.4% Identity: 43% PDB header:rna binding protein/rna Chain: A: PDB Molecule:putative uncharacterized protein tthb192; PDBTitle: structure of thermus thermophilus cse3 bound to an rna representing a2 pre-cleavage complex Phyre2 PDB 1dl5 chain A Region: 29 - 89 Aligned: 47 Modelled: 61 Confidence: 10.7% Identity: 36% PDB header:transferase Chain: A: PDB Molecule:protein-l-isoaspartate o-methyltransferase; PDBTitle: protein-l-isoaspartate o-methyltransferase Phyre2 PDB 1bhu chain A Region: 94 - 117 Aligned: 24 Modelled: 24 Confidence: 8.6% Identity: 42% Fold: gamma-Crystallin-like Superfamily: gamma-Crystallin-like Family: Streptomyces metalloproteinase inhibitor, SMPI Phyre2 PDB 1wj9 chain A Region: 114 - 127 Aligned: 14 Modelled: 14 Confidence: 8.4% Identity: 43% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:crispr-associated protein; PDBTitle: crystal structure of a crispr-associated protein from2 thermus thermophilus Phyre2 PDB 4y7l chain B Region: 19 - 98 Aligned: 68 Modelled: 68 Confidence: 8.3% Identity: 21% PDB header:membrane protein Chain: B: PDB Molecule:type vi secretion protein icmf; PDBTitle: t6ss protein tssm c-terminal domain (869-1107) from eaec Phyre2 PDB 3oe3 chain B Region: 64 - 85 Aligned: 22 Modelled: 22 Confidence: 8.2% Identity: 23% PDB header:hydrolase inhibitor Chain: B: PDB Molecule:putative periplasmic protein; PDBTitle: crystal structure of plic-st, periplasmic lysozyme inhibitor of c-type2 lysozyme from salmonella typhimurium Phyre2 PDB 3tbd chain A Region: 53 - 69 Aligned: 17 Modelled: 17 Confidence: 7.7% Identity: 24% PDB header:cell adhesion Chain: A: PDB Molecule:netrin-g2; PDBTitle: crystal structure of domain vi and le1 of human netrin-g2 Phyre2 PDB 1hlc chain A Region: 3 - 64 Aligned: 55 Modelled: 62 Confidence: 7.6% Identity: 9% Fold: Concanavalin A-like lectins/glucanases Superfamily: Concanavalin A-like lectins/glucanases Family: Galectin (animal S-lectin) Phyre2 PDB 2bkd chain N Region: 44 - 72 Aligned: 29 Modelled: 29 Confidence: 7.3% Identity: 34% PDB header:nuclear protein Chain: N: PDB Molecule:fragile x mental retardation 1 protein; PDBTitle: structure of the n-terminal domain of fragile x mental retardation2 protein Phyre2 PDB 5u0a chain A Region: 114 - 129 Aligned: 16 Modelled: 16 Confidence: 7.3% Identity: 13% PDB header:immune system Chain: A: PDB Molecule:crispr-associated protein, cse3 family; PDBTitle: crispr rna-guided surveillance complex Phyre2 PDB 2csb chain A domain 2 Region: 63 - 78 Aligned: 16 Modelled: 16 Confidence: 6.7% Identity: 44% Fold: SAM domain-like Superfamily: RuvA domain 2-like Family: Topoisomerase V repeat domain Phyre2 PDB 4aqt chain A Region: 53 - 69 Aligned: 17 Modelled: 17 Confidence: 6.7% Identity: 18% PDB header:cell adhesion Chain: A: PDB Molecule:laminin subunit gamma-1; PDBTitle: laminin gamma1 ln-le1-2 structure Phyre2 PDB 6ixh chain Q Region: 19 - 98 Aligned: 69 Modelled: 69 Confidence: 6.7% Identity: 14% PDB header:membrane protein Chain: Q: PDB Molecule:type vi secretion system tssm; PDBTitle: type vi secretion system membrane core complex Phyre2 PDB 3zyi chain B Region: 53 - 69 Aligned: 17 Modelled: 17 Confidence: 6.7% Identity: 24% PDB header:cell adhesion Chain: B: PDB Molecule:netrin-g2; PDBTitle: netring2 in complex with ngl2 Phyre2 PDB 1w6n chain A Region: 3 - 64 Aligned: 55 Modelled: 62 Confidence: 6.5% Identity: 11% Fold: Concanavalin A-like lectins/glucanases Superfamily: Concanavalin A-like lectins/glucanases Family: Galectin (animal S-lectin) Phyre2 PDB 4wnx chain A Region: 53 - 69 Aligned: 17 Modelled: 17 Confidence: 6.4% Identity: 35% PDB header:laminin binding protein Chain: A: PDB Molecule:netrin-4; PDBTitle: netrin 4 lacking the c-terminal domain Phyre2 1 d1wj9a2 2 c4dzdA_ 3 c4ld7N_ 4 c4whiA_ 5 c3qrqA_ 6 c1dl5A_ 7 d1bhua_ 8 c1wj9A_ 9 c4y7lB_ 10 c3oe3B_ 11 c3tbdA_ 12 d1hlca_ 13 c2bkdN_ 14 c5u0aA_ 15 d2csba2 16 c4aqtA_ 17 c6ixhQ_ 18 c3zyiB_ 19 d1w6na_ 20 c4wnxA_ 21 22 23 24 25 26 27 28