1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	V	L	D	G	V	V	S	D	T	R	R	S	R	T	I	A	A	R	Q	Q	T	I	W	D	V	L	A	D	F	G	S	L	S	S	W	V	E	G	V	D	H	S	C	V	L	N	H	G	P	D	G	G	A	L	G	S	T	R	R
Secondary structure
SS confidence
Disorder		?	?	?	?			?		?	?																																				?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	Q	V	G	R	N	T	L	V	E	R	V	I	E	F	D	P	P	T	T	L	A	Y	R	I	E	G	L	P	A	R	L	R	K	V	T	N	R	W	T	L	R	P	A	D	P	V	G	A	V	T	V	V	T	L	T	S	T	I	E
Secondary structure
SS confidence
Disorder						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.
Sequence		I	G	G	N	P	L	A	R	L	A	E	L	V	V	G	R	A	M	A	K	R	S	N	T	M	L	A	G	L	A	Q	R	L	E	D	K	H	G
Secondary structure
SS confidence
Disorder																																				?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 11%) Alpha helix ( 30%) Beta strand ( 40%)

Rank Aligned region

PDB 2d4r chain A domain 1 Region: 8 - 156 Aligned: 144 Modelled: 149 Confidence: 99.9% Identity: 18% Fold: TBP-like Superfamily: Bet v1-like Family: oligoketide cyclase/dehydrase-like Phyre2 PDB 3tfz chain B Region: 7 - 156 Aligned: 148 Modelled: 150 Confidence: 99.9% Identity: 19% PDB header:biosynthetic protein Chain: B: PDB Molecule:cyclase; PDBTitle: crystal structure of zhui aromatase/cyclase from streptomcyes sp.2 r1128 Phyre2 PDB 1t17 chain A Region: 7 - 158 Aligned: 143 Modelled: 152 Confidence: 99.9% Identity: 16% Fold: TBP-like Superfamily: Bet v1-like Family: oligoketide cyclase/dehydrase-like Phyre2 PDB 4xrw chain A Region: 7 - 158 Aligned: 146 Modelled: 152 Confidence: 99.9% Identity: 14% PDB header:lyase Chain: A: PDB Molecule:bexl; PDBTitle: crystal structure of the di-domain aro/cyc bexl from the be-7585a2 biosynthetic pathway Phyre2 PDB 2rer chain A domain 1 Region: 6 - 157 Aligned: 147 Modelled: 152 Confidence: 99.9% Identity: 15% Fold: TBP-like Superfamily: Bet v1-like Family: oligoketide cyclase/dehydrase-like Phyre2 PDB 2kf2 chain A Region: 7 - 158 Aligned: 147 Modelled: 152 Confidence: 99.9% Identity: 17% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative polyketide cyclase; PDBTitle: solution nmr structure of of streptomyces coelicolor2 polyketide cyclase sco5315. northeast structural genomics3 consortium target rr365 Phyre2 PDB 5z8o chain A Region: 10 - 155 Aligned: 140 Modelled: 146 Confidence: 99.8% Identity: 16% PDB header:unknown function Chain: A: PDB Molecule:cyclase/dehydrase; PDBTitle: structural of start superfamily protein msmeg_0129 from mycobacterium2 smegmatis Phyre2 PDB 2pcs chain A domain 1 Region: 8 - 156 Aligned: 147 Modelled: 149 Confidence: 99.8% Identity: 14% Fold: TBP-like Superfamily: Bet v1-like Family: CoxG-like Phyre2 PDB 2le1 chain A Region: 7 - 157 Aligned: 149 Modelled: 151 Confidence: 99.8% Identity: 15% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution nmr structure of tfu_2981 from thermobifida fusca, northeast2 structural genomics consortium target tfr85a Phyre2 PDB 2ns9 chain A domain 1 Region: 8 - 156 Aligned: 144 Modelled: 149 Confidence: 99.8% Identity: 17% Fold: TBP-like Superfamily: Bet v1-like Family: CoxG-like Phyre2 PDB 4xrt chain B Region: 3 - 158 Aligned: 153 Modelled: 156 Confidence: 99.8% Identity: 18% PDB header:lyase Chain: B: PDB Molecule:stfq aromatase/cyclase; PDBTitle: crystal structure of the di-domain aro/cyc stfq from the steffimycin2 biosynthetic pathway Phyre2 PDB 5vgl chain A Region: 3 - 155 Aligned: 144 Modelled: 153 Confidence: 99.8% Identity: 10% PDB header:isomerase Chain: A: PDB Molecule:lachrymatory-factor synthase; PDBTitle: crystal structure of lachrymatory factor synthase from allium cepa Phyre2 PDB 5wox chain A Region: 9 - 154 Aligned: 139 Modelled: 146 Confidence: 99.8% Identity: 16% PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: nmr solution structure of kany protein (ms6282) using two 4d-spectra Phyre2 PDB 3p9v chain A Region: 6 - 157 Aligned: 150 Modelled: 152 Confidence: 99.8% Identity: 18% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: high resolution crystal structure of protein maqu_3174 from2 marinobacter aquaeolei, northeast structural genomics consortium3 target mqr197 Phyre2 PDB 3cnw chain A domain 1 Region: 8 - 155 Aligned: 137 Modelled: 148 Confidence: 99.8% Identity: 15% Fold: TBP-like Superfamily: Bet v1-like Family: Atu1531-like Phyre2 PDB 2b79 chain A domain 1 Region: 8 - 154 Aligned: 136 Modelled: 147 Confidence: 99.8% Identity: 8% Fold: TBP-like Superfamily: Bet v1-like Family: Smu440-like Phyre2 PDB 4n0g chain C Region: 9 - 155 Aligned: 139 Modelled: 147 Confidence: 99.8% Identity: 15% PDB header:hydrolase/receptor Chain: C: PDB Molecule:abscisic acid receptor pyl13; PDBTitle: crystal structure of pyl13-pp2ca complex Phyre2 PDB 4oic chain A Region: 6 - 155 Aligned: 146 Modelled: 150 Confidence: 99.8% Identity: 18% PDB header:hormone receptor/hydrolase Chain: A: PDB Molecule:bet v i allergen-like; PDBTitle: crystal structrual of a soluble protein Phyre2 PDB 2m47 chain A Region: 8 - 156 Aligned: 141 Modelled: 149 Confidence: 99.7% Identity: 16% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein cgl2373; PDBTitle: solution nmr structure of the polyketide_cyc-like protein cgl2372 from2 corynebacterium glutamicum, northeast structural genomics consortium3 target cgr160 Phyre2 PDB 2kcz chain A Region: 6 - 154 Aligned: 144 Modelled: 149 Confidence: 99.7% Identity: 14% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein dr_a0006; PDBTitle: solution nmr structure of the c-terminal domain of protein2 dr_a0006 from deinococcus radiodurans. northeast3 structural genomics consortium target drr147d Phyre2 1 d2d4ra1 2 c3tfzB_ 3 d1t17a_ 4 c4xrwA_ 5 d2rera1 6 c2kf2A_ 7 c5z8oA_ 8 d2pcsa1 9 c2le1A_ 10 d2ns9a1 11 c4xrtB_ 12 c5vglA_ 13 c5woxA_ 14 c3p9vA_ 15 d3cnwa1 16 d2b79a1 17 c4n0gC_ 18 c4oicA_ 19 c2m47A_ 20 c2kczA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99