1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	P	P	N	Q	D	A	Q	E	G	R	P	D	S	P	T	A	E	V	V	D	V	R	R	G	M	F	G	V	S	G	T	G	D	T	S	G	Y	G	R	L	V	R	Q	V	V	L	P	G	S	S	P	R	P	Y	G	G	Y	F
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?					?				?	?	?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	D	I	V	D	R	L	A	E	A	L	R	H	E	R	V	E	F	E	D	A	V	E	K	V	V	V	Y	R	D	E	L	T	L	H	V	R	R	D	L	L	P	R	V	A	Q	R	L	R	D	E	P	E	L	R	F	E	L	C	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	V	S	G	V	H	Y	P	H	E	T	G	R	E	L	H	A	V	Y	P	L	Q	S	I	T	H	N	R	R	L	R	L	E	V	S	A	P	D	S	D	P	H	I	P	S	L	F	A	I	Y	P	T	N	D	W	H	E	R	E	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.
Sequence		Y	D	F	F	G	I	I	F	D	G	H	P	A	L	T	R	I	E	M	P	D	D	W	Q	G	H	P	Q	R	K	D	Y	P	L	G	G	I	P	V	E	Y	K	G	A	Q	I	P	P	P	D	E	R	R	G	Y	N
Secondary structure
SS confidence
Disorder																																									?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 26%) Alpha helix ( 22%) Beta strand ( 26%)

Rank Aligned region

PDB 6gcs chain G Region: 60 - 236 Aligned: 171 Modelled: 177 Confidence: 100.0% Identity: 33% PDB header:oxidoreductase Chain: G: PDB Molecule:30-kda protein (nugm); PDBTitle: cryo-em structure of respiratory complex i from yarrowia lipolytica Phyre2 PDB 5ldw chain C Region: 54 - 235 Aligned: 180 Modelled: 182 Confidence: 100.0% Identity: 29% PDB header:oxidoreductase Chain: C: PDB Molecule:nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, PDBTitle: structure of mammalian respiratory complex i, class1 Phyre2 PDB 3mcr chain A Region: 49 - 195 Aligned: 147 Modelled: 147 Confidence: 100.0% Identity: 63% PDB header:oxidoreductase Chain: A: PDB Molecule:nadh dehydrogenase, subunit c; PDBTitle: crystal structure of nadh dehydrogenase subunit c (tfu_2693) from2 thermobifida fusca yx-er1 at 2.65 a resolution Phyre2 PDB 2fug chain 5 domain 1 Region: 66 - 235 Aligned: 158 Modelled: 170 Confidence: 100.0% Identity: 32% Fold: Nqo5-like Superfamily: Nqo5-like Family: Nqo5-like Phyre2 PDB 6cfw chain K Region: 64 - 227 Aligned: 159 Modelled: 164 Confidence: 100.0% Identity: 24% PDB header:membrane protein Chain: K: PDB Molecule:membrane-bound hydrogenase subunit beta; PDBTitle: cryoem structure of a respiratory membrane-bound hydrogenase Phyre2 PDB 6hum chain J Region: 66 - 219 Aligned: 146 Modelled: 151 Confidence: 100.0% Identity: 33% PDB header:proton transport Chain: J: PDB Molecule:nad(p)h-quinone oxidoreductase subunit j; PDBTitle: structure of the photosynthetic complex i from thermosynechococcus2 elongatus Phyre2 PDB 2p06 chain A domain 1 Region: 49 - 107 Aligned: 49 Modelled: 59 Confidence: 70.4% Identity: 45% Fold: all-alpha NTP pyrophosphatases Superfamily: all-alpha NTP pyrophosphatases Family: AF0060-like Phyre2 PDB 2p06 chain A Region: 49 - 107 Aligned: 49 Modelled: 59 Confidence: 70.4% Identity: 45% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein af_0060; PDBTitle: crystal structure of a predicted coding region af_0060 from2 archaeoglobus fulgidus dsm 4304 Phyre2 PDB 3s2x chain B Region: 15 - 110 Aligned: 79 Modelled: 89 Confidence: 59.1% Identity: 25% PDB header:transferase Chain: B: PDB Molecule:acetyl-coa synthase subunit alpha; PDBTitle: structure of acetyl-coenzyme a synthase alpha subunit c-terminal2 domain Phyre2 PDB 1ru3 chain A Region: 15 - 110 Aligned: 76 Modelled: 96 Confidence: 49.8% Identity: 25% Fold: Prismane protein-like Superfamily: Prismane protein-like Family: Acetyl-CoA synthase Phyre2 PDB 3git chain A Region: 15 - 110 Aligned: 76 Modelled: 96 Confidence: 35.4% Identity: 28% PDB header:transferase Chain: A: PDB Molecule:carbon monoxide dehydrogenase/acetyl-coa synthase subunit PDBTitle: crystal structure of a truncated acetyl-coa synthase Phyre2 PDB 1oao chain C Region: 15 - 110 Aligned: 76 Modelled: 96 Confidence: 34.9% Identity: 28% Fold: Prismane protein-like Superfamily: Prismane protein-like Family: Acetyl-CoA synthase Phyre2 PDB 3kfw chain X Region: 191 - 212 Aligned: 22 Modelled: 22 Confidence: 21.7% Identity: 36% PDB header:structural genomics, unknown function Chain: X: PDB Molecule:uncharacterized protein; PDBTitle: uncharacterized protein rv0674 from mycobacterium tuberculosis Phyre2 PDB 1bl1 chain A Region: 177 - 189 Aligned: 13 Modelled: 13 Confidence: 14.1% Identity: 46% PDB header:hormone receptor Chain: A: PDB Molecule:parathyroid hormone receptor; PDBTitle: pth receptor n-terminus fragment, nmr, 1 structure Phyre2 PDB 3kwl chain A Region: 163 - 183 Aligned: 21 Modelled: 21 Confidence: 13.8% Identity: 19% PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a hypothetical protein from helicobacter pylori Phyre2 PDB 2fq8 chain A Region: 58 - 71 Aligned: 14 Modelled: 14 Confidence: 12.1% Identity: 29% PDB header:unknown function Chain: A: PDB Molecule:2f; PDBTitle: nmr structure of 2f associated with lipid disc Phyre2 PDB 2fq5 chain A Region: 58 - 71 Aligned: 14 Modelled: 14 Confidence: 12.1% Identity: 29% PDB header:unknown function Chain: A: PDB Molecule:peptide 2f; PDBTitle: nmr structure of 2f associated with lipid disc Phyre2 PDB 2f05 chain A domain 1 Region: 177 - 203 Aligned: 27 Modelled: 27 Confidence: 11.5% Identity: 22% Fold: PAH2 domain Superfamily: PAH2 domain Family: PAH2 domain Phyre2 PDB 3v8v chain B Region: 59 - 109 Aligned: 49 Modelled: 51 Confidence: 9.7% Identity: 16% PDB header:transferase Chain: B: PDB Molecule:ribosomal rna large subunit methyltransferase l; PDBTitle: crystal structure of bifunctional methyltransferase ycby (rlmlk) from2 escherichia coli, sam binding Phyre2 PDB 5a96 chain A Region: 166 - 192 Aligned: 27 Modelled: 27 Confidence: 9.1% Identity: 44% PDB header:viral protein Chain: A: PDB Molecule:polyhedrin; PDBTitle: crystal structure of lymantria dispar cpv14 polyhedra Phyre2 1 c6gcsG_ 2 c5ldwC_ 3 c3mcrA_ 4 d2fug51 5 c6cfwK_ 6 c6humJ_ 7 d2p06a1 8 c2p06A_ 9 c3s2xB_ 10 d1ru3a_ 11 c3gitA_ 12 d1oaoc_ 13 c3kfwX_ 14 c1bl1A_ 15 c3kwlA_ 16 c2fq8A_ 17 c2fq5A_ 18 d2f05a1 19 c3v8vB_ 20 c5a96A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46