Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD3159c_(PPE53)_3527388_3529160
DateThu Aug 8 16:20:34 BST 2019
Unique Job ID15f609231b669385
SequenceMNYSVLPPEI ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:59.669 Y:71.855 Z:71.719
Model (left) based on template c5xfsB_
Top template information
PDB header:protein transport
Chain: B: PDB Molecule:ppe family protein ppe15;
PDBTitle: crystal structure of pe8-ppe15 in complex with espg5 from m.2 tuberculosis
Confidence and coverage
Confidence:100.0% Coverage: 29%
173 residues ( 29% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
Warning: 71% of your sequence is predicted disordered. Disordered regions cannot be meaningfully predicted.
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Sequence analysis 

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Secondary structure and disorder prediction [Show] 

Domain analysis [Show] 

Detailed template information [Hide] 

 

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Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c5xfsB_
100.0 52
PDB header:protein transport
Chain: B: PDB Molecule:ppe family protein ppe15;
PDBTitle: crystal structure of pe8-ppe15 in complex with espg5 from m.2 tuberculosis
2d2g38b1
100.0 28
Fold:Ferritin-like
Superfamily:PE/PPE dimer-like
Family:PPE
3c2g38B_
100.0 28
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:ppe family protein;
PDBTitle: a pe/ppe protein complex from mycobacterium tuberculosis
4c4xy3A_
100.0 19
PDB header:protein transport
Chain: A: PDB Molecule:esx-1 secretion-associated protein espb;
PDBTitle: structure of esx-1 secreted protein espb
5c4wj2A_
99.0 15
PDB header:unknown function
Chain: A: PDB Molecule:antigen mtb48;
PDBTitle: mycobacterial protein
6c2vs0B_
98.2 14
PDB header:cell invasion
Chain: B: PDB Molecule:virulence factor esxa;
PDBTitle: structural analysis of homodimeric staphylococcal aureus2 virulence factor esxa
7c3gvmA_
98.0 10
PDB header:viral protein
Chain: A: PDB Molecule:putative uncharacterized protein sag1039;
PDBTitle: structure of the homodimeric wxg-100 family protein from streptococcus2 agalactiae
8c4iogD_
98.0 18
PDB header:unknown function
Chain: D: PDB Molecule:secreted protein esxb;
PDBTitle: the crystal structure of a secreted protein esxb (wild-type, in p212 space group) from bacillus anthracis str. sterne
9c3zbhC_
97.9 13
PDB header:unknown function
Chain: C: PDB Molecule:esxa;
PDBTitle: geobacillus thermodenitrificans esxa crystal form i
10d1wa8a1
97.5 20
Fold:Ferritin-like
Superfamily:EsxAB dimer-like
Family:ESAT-6 like
11c4lwsA_
96.9 16
PDB header:unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: esxa : esxb (semet) hetero-dimer from thermomonospora curvata
12c4lwsB_
96.7 10
PDB header:unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: esxa : esxb (semet) hetero-dimer from thermomonospora curvata
13d1wa8b1
96.5 13
Fold:Ferritin-like
Superfamily:EsxAB dimer-like
Family:ESAT-6 like
14c4i0xA_
96.1 19
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:esat-6-like protein mab_3112;
PDBTitle: crystal structure of the mycobacterum abscessus esxef (mab_3112-2 mab_3113) complex
15c2kg7B_
94.3 18
PDB header:unknown function
Chain: B: PDB Molecule:esat-6-like protein esxh;
PDBTitle: structure and features of the complex formed by the tuberculosis2 virulence factors rv0287 and rv0288
16c4i0xJ_
85.0 27
PDB header:structural genomics, unknown function
Chain: J: PDB Molecule:esat-6-like protein mab_3113;
PDBTitle: crystal structure of the mycobacterum abscessus esxef (mab_3112-2 mab_3113) complex
17d1ui5a2
79.3 26
Fold:Tetracyclin repressor-like, C-terminal domain
Superfamily:Tetracyclin repressor-like, C-terminal domain
Family:Tetracyclin repressor-like, C-terminal domain
18d1xkna_
27.1 17
Fold:Pentein, beta/alpha-propeller
Superfamily:Pentein
Family:Porphyromonas-type peptidylarginine deiminase
19c2iu1A_
26.6 33
PDB header:transcription
Chain: A: PDB Molecule:eukaryotic translation initiation factor 5;
PDBTitle: crystal structure of eif5 c-terminal domain
20c2ahmG_
25.7 18
PDB header:viral protein, replication
Chain: G: PDB Molecule:replicase polyprotein 1ab, heavy chain;
PDBTitle: crystal structure of sars-cov super complex of non-structural2 proteins: the hexadecamer
21c3h6pB_
not modelled 24.0 33
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:esat-6 like protein esxs;
PDBTitle: crystal structure of rv3019c-rv3020c from mycobacterium tuberculosis
22c2kg7A_
not modelled 22.5 37
PDB header:unknown function
Chain: A: PDB Molecule:uncharacterized protein esxg (pe family protein);
PDBTitle: structure and features of the complex formed by the tuberculosis2 virulence factors rv0287 and rv0288
23c5frgA_
not modelled 21.8 63
PDB header:protein binding
Chain: A: PDB Molecule:formin-binding protein 1-like;
PDBTitle: the nmr structure of the cdc42-interacting region of toca1
24c2fulE_
not modelled 20.9 33
PDB header:translation
Chain: E: PDB Molecule:eukaryotic translation initiation factor 5;
PDBTitle: crystal structure of the c-terminal domain of s. cerevisiae eif5
25c2l5aA_
not modelled 18.0 22
PDB header:nuclear protein
Chain: A: PDB Molecule:histone h3-like centromeric protein cse4, protein scm3,
PDBTitle: structural basis for recognition of centromere specific histone h32 variant by nonhistone scm3
26c3ub0D_
not modelled 15.0 13
PDB header:replication
Chain: D: PDB Molecule:non-structural protein 6, nsp6,;
PDBTitle: crystal structure of the nonstructural protein 7 and 8 complex of2 feline coronavirus
27c1bkvA_
not modelled 15.0 38
PDB header:structural protein
Chain: A: PDB Molecule:t3-785;
PDBTitle: collagen
28c2kp7A_
not modelled 14.8 20
PDB header:hydrolase
Chain: A: PDB Molecule:crossover junction endonuclease mus81;
PDBTitle: solution nmr structure of the mus81 n-terminal hhh.2 northeast structural genomics consortium target mmt1a
29c3zfsA_
not modelled 14.6 16
PDB header:oxidoreductase
Chain: A: PDB Molecule:f420-reducing hydrogenase, subunit alpha;
PDBTitle: cryo-em structure of the f420-reducing nife-hydrogenase from a2 methanogenic archaeon with bound substrate
30c3jywF_
not modelled 14.5 61
PDB header:ribosome
Chain: F: PDB Molecule:60s ribosomal protein l7(a);
PDBTitle: structure of the 60s proteins for eukaryotic ribosome based on cryo-em2 map of thermomyces lanuginosus ribosome at 8.9a resolution
31c2ke4A_
not modelled 14.5 63
PDB header:membrane protein
Chain: A: PDB Molecule:cdc42-interacting protein 4;
PDBTitle: the nmr structure of the tc10 and cdc42 interacting domain2 of cip4
32c4n91A_
not modelled 14.4 17
PDB header:transport protein
Chain: A: PDB Molecule:trap dicarboxylate transporter, dctp subunit;
PDBTitle: crystal structure of a trap periplasmic solute binding protein from2 anaerococcus prevotii dsm 20548 (apre_1383), target efi-510023, with3 bound alpha/beta d-glucuronate
33d1paqa_
not modelled 14.0 15
Fold:alpha-alpha superhelix
Superfamily:ARM repeat
Family:MIF4G domain-like
34c1paqA_
not modelled 14.0 15
PDB header:translation
Chain: A: PDB Molecule:translation initiation factor eif-2b epsilon
PDBTitle: crystal structure of the catalytic fragment of eukaryotic2 initiation factor 2b epsilon
35c1bkvB_
not modelled 13.9 38
PDB header:structural protein
Chain: B: PDB Molecule:t3-785;
PDBTitle: collagen
36c1bkvC_
not modelled 13.9 38
PDB header:structural protein
Chain: C: PDB Molecule:t3-785;
PDBTitle: collagen
37c2l5bA_
not modelled 13.1 53
PDB header:apoptosis
Chain: A: PDB Molecule:activator of apoptosis harakiri;
PDBTitle: solution structure of the transmembrane domain of bcl-2 member2 harakiri in micelles
38c3juiA_
not modelled 11.5 23
PDB header:translation
Chain: A: PDB Molecule:translation initiation factor eif-2b subunit epsilon;
PDBTitle: crystal structure of the c-terminal domain of human translation2 initiation factor eif2b epsilon subunit
39d2fgga1
not modelled 10.5 40
Fold:dsRBD-like
Superfamily:Rv2632c-like
Family:Rv2632c-like
40d2ewoa1
not modelled 10.1 22
Fold:Pentein, beta/alpha-propeller
Superfamily:Pentein
Family:Porphyromonas-type peptidylarginine deiminase
41c3trhI_
not modelled 9.7 10
PDB header:lyase
Chain: I: PDB Molecule:phosphoribosylaminoimidazole carboxylase
PDBTitle: structure of a phosphoribosylaminoimidazole carboxylase catalytic2 subunit (pure) from coxiella burnetii
42c4wpyA_
not modelled 8.8 15
PDB header:de novo protein
Chain: A: PDB Molecule:protein dl-rv1738;
PDBTitle: racemic crystal structure of rv1738 from mycobacterium tuberculosis2 (form-ii)
43c2jbwB_
not modelled 8.4 15
PDB header:hydrolase
Chain: B: PDB Molecule:2,6-dihydroxy-pseudo-oxynicotine hydrolase;
PDBTitle: crystal structure of the 2,6-dihydroxy-pseudo-oxynicotine hydrolase.
44d2jbwa1
not modelled 8.2 15
Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:2,6-dihydropseudooxynicotine hydrolase-like
45c3lyrA_
not modelled 8.1 5
PDB header:transcription activator
Chain: A: PDB Molecule:transcription factor coe1;
PDBTitle: human early b-cell factor 1 (ebf1) dna-binding domain
46c2np3A_
not modelled 7.9 9
PDB header:transcription
Chain: A: PDB Molecule:putative tetr-family regulator;
PDBTitle: crystal structure of tetr-family regulator (sco0857) from streptomyces2 coelicolor a3.
47c4mnpA_
not modelled 7.7 16
PDB header:sugar binding protein
Chain: A: PDB Molecule:n-acetylneuraminate-binding protein;
PDBTitle: structure of the sialic acid binding protein from fusobacterium2 nucleatum subsp. nucleatum atcc 25586
48c3mveB_
not modelled 7.3 20
PDB header:lyase
Chain: B: PDB Molecule:upf0255 protein vv1_0328;
PDBTitle: crystal structure of a novel pyruvate decarboxylase
49c5hl8B_
not modelled 7.2 24
PDB header:protein transport
Chain: B: PDB Molecule:type ii secretion system protein l;
PDBTitle: 1.93 angstrom resolution crystal structure of a pullulanase-specific2 type ii secretion system integral cytoplasmic membrane protein gspl3 (c-terminal fragment; residues 309-397) from klebsiella pneumoniae4 subsp. pneumoniae ntuh-k2044
50c3b50A_
not modelled 7.2 15
PDB header:transport protein
Chain: A: PDB Molecule:sialic acid-binding periplasmic protein siap;
PDBTitle: structure of h. influenzae sialic acid binding protein2 bound to neu5ac.
51d1fcda3
not modelled 7.2 23
Fold:CO dehydrogenase flavoprotein C-domain-like
Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain
52c2hzkB_
not modelled 7.2 15
PDB header:ligand binding, transport protein
Chain: B: PDB Molecule:trap-t family sorbitol/mannitol transporter, periplasmic
PDBTitle: crystal structures of a sodium-alpha-keto acid binding subunit from a2 trap transporter in its open form
53c4grdA_
not modelled 7.0 19
PDB header:lyase,isomerase
Chain: A: PDB Molecule:phosphoribosylaminoimidazole carboxylase catalytic subunit;
PDBTitle: crystal structure of phosphoribosylaminoimidazole carboxylase2 catalytic subunit from burkholderia cenocepacia j2315
54c6hu9u_
not modelled 6.9 18
PDB header:oxidoreductase/electron transport
Chain: U: PDB Molecule:cytochrome b-c1 complex subunit 10;
PDBTitle: iii2-iv2 mitochondrial respiratory supercomplex from s. cerevisiae
55c5lzkB_
not modelled 6.9 4
PDB header:structural genomics
Chain: B: PDB Molecule:protein fam83b;
PDBTitle: structure of the domain of unknown function duf1669 from human fam83b
56c5ec0A_
not modelled 6.8 33
PDB header:structural protein
Chain: A: PDB Molecule:alp7a;
PDBTitle: crystal structure of actin-like protein alp7a
57c3qthA_
not modelled 6.8 8
PDB header:unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a dinb-like protein (cps_3021) from colwellia2 psychrerythraea 34h at 2.20 a resolution
58c4k0dB_
not modelled 6.7 26
PDB header:signaling protein
Chain: B: PDB Molecule:periplasmic sensor hybrid histidine kinase;
PDBTitle: periplasmic sensor domain of sensor histidine kinase, adeh_2942
59c5vmoB_
not modelled 6.4 50
PDB header:viral protein/apoptosis
Chain: B: PDB Molecule:bcl-2 interacting mediator of cell death;
PDBTitle: crystal structure of grouper iridovirus giv66:bim complex
60c3j21Y_
not modelled 6.4 25
PDB header:ribosome
Chain: Y: PDB Molecule:50s ribosomal protein l30p;
PDBTitle: promiscuous behavior of proteins in archaeal ribosomes revealed by2 cryo-em: implications for evolution of eukaryotic ribosomes (50s3 ribosomal proteins)
61d1luaa2
not modelled 6.4 29
Fold:Aminoacid dehydrogenase-like, N-terminal domain
Superfamily:Aminoacid dehydrogenase-like, N-terminal domain
Family:Methylene-tetrahydromethanopterin dehydrogenase
62c2dbfA_
not modelled 6.4 20
PDB header:signaling protein
Chain: A: PDB Molecule:nuclear factor nf-kappa-b p105 subunit;
PDBTitle: solution structure of the death domain in human nuclear2 factor nf-kappa-b p105 subunit
63c2nvjA_
not modelled 6.3 40
PDB header:hydrolase
Chain: A: PDB Molecule:25mer peptide from vacuolar atp synthase subunit
PDBTitle: nmr structures of transmembrane segment from subunit a from2 the yeast proton v-atpase
64c3r5zB_
not modelled 6.3 10
PDB header:unknown function
Chain: B: PDB Molecule:putative uncharacterized protein;
PDBTitle: structure of a deazaflavin-dependent reductase from nocardia2 farcinica, with co-factor f420
65c3j3bF_
not modelled 6.3 31
PDB header:ribosome
Chain: F: PDB Molecule:60s ribosomal protein l7;
PDBTitle: structure of the human 60s ribosomal proteins
66c3rggD_
not modelled 6.2 13
PDB header:lyase
Chain: D: PDB Molecule:phosphoribosylaminoimidazole carboxylase, pure protein;
PDBTitle: crystal structure of treponema denticola pure bound to air
67d1kx5a_
not modelled 6.2 20
Fold:Histone-fold
Superfamily:Histone-fold
Family:Nucleosome core histones
68c2kwuA_
not modelled 6.1 31
PDB header:protein binding/signaling protein
Chain: A: PDB Molecule:dna polymerase iota;
PDBTitle: solution structure of ubm2 of murine polymerase iota in complex with2 ubiquitin
69c4i6jB_
not modelled 6.0 22
PDB header:transcription
Chain: B: PDB Molecule:f-box/lrr-repeat protein 3;
PDBTitle: a ubiquitin ligase-substrate complex
70c1nauA_
not modelled 5.9 23
PDB header:hormone/growth factor
Chain: A: PDB Molecule:glucagon;
PDBTitle: nmr solution structure of the glucagon antagonist [deshis1,2 desphe6, glu9]glucagon amide in the presence of3 perdeuterated dodecylphosphocholine micelles
71c1d1dA_
not modelled 5.9 14
PDB header:viral protein
Chain: A: PDB Molecule:protein (capsid protein);
PDBTitle: nmr solution structure of the capsid protein from rous2 sarcoma virus
72c6ansD_
not modelled 5.7 14
PDB header:unknown function
Chain: D: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a putative uncharacterized protein from2 burkholderia cenocepacia
73c3j39F_
not modelled 5.7 38
PDB header:ribosome
Chain: F: PDB Molecule:60s ribosomal protein l7;
PDBTitle: structure of the d. melanogaster 60s ribosomal proteins
74c2hueB_
not modelled 5.7 20
PDB header:dna binding protein
Chain: B: PDB Molecule:histone h3;
PDBTitle: structure of the h3-h4 chaperone asf1 bound to histones h3 and h4
75c4c5eG_
not modelled 5.7 33
PDB header:transcription
Chain: G: PDB Molecule:polycomb protein pho;
PDBTitle: crystal structure of the minimal pho-sfmbt complex (p21 spacegroup)
76c4c5eH_
not modelled 5.7 33
PDB header:transcription
Chain: H: PDB Molecule:polycomb protein pho;
PDBTitle: crystal structure of the minimal pho-sfmbt complex (p21 spacegroup)
77c5ietA_
not modelled 5.6 32
PDB header:gene regulation
Chain: A: PDB Molecule:bacterial proteasome activator;
PDBTitle: crystal structure of mycobacterium tuberculosis atp-independent2 proteasome activator
78c3bb9D_
not modelled 5.6 9
PDB header:unknown function
Chain: D: PDB Molecule:putative orphan protein;
PDBTitle: crystal structure of a putative ketosteroid isomerase (sfri_1973) from2 shewanella frigidimarina ncimb 400 at 1.80 a resolution
79d1eqzg_
not modelled 5.5 20
Fold:Histone-fold
Superfamily:Histone-fold
Family:Nucleosome core histones
80c1jrjA_
not modelled 5.5 27
PDB header:hormone/growth factor
Chain: A: PDB Molecule:exendin-4;
PDBTitle: solution structure of exendin-4 in 30-vol% trifluoroethanol
81c2jtwA_
not modelled 5.5 50
PDB header:membrane protein
Chain: A: PDB Molecule:transmembrane helix 7 of yeast vatpase;
PDBTitle: solution structure of tm7 bound to dpc micelles
82c4oanB_
not modelled 5.4 19
PDB header:membrane protein/protein transport
Chain: B: PDB Molecule:trap dicarboxylate transporter dctp subunit;
PDBTitle: crystal structure of a trap periplasmic solute binding protein from2 rhodopseudomonas palustris haa2 (rpb_2686), target efi-510221, with3 density modeled as (s)-2-hydroxy-2-methyl-3-oxobutanoate ((s)-2-4 acetolactate)
83c4deyB_
not modelled 5.3 18
PDB header:transport protein
Chain: B: PDB Molecule:voltage-dependent l-type calcium channel subunit alpha-1c;
PDBTitle: crystal structure of the voltage dependent calcium channel beta-22 subunit in complex with the cav1.2 i-ii linker.
84c1d0rA_
not modelled 5.3 40
PDB header:hormone/growth factor
Chain: A: PDB Molecule:glucagon-like peptide-1-(7-36)-amide;
PDBTitle: solution structure of glucagon-like peptide-1-(7-36)-amide in2 trifluoroethanol/water
85c2yfwC_
not modelled 5.3 20
PDB header:cell cycle
Chain: C: PDB Molecule:histone h3-like centromeric protein cse4;
PDBTitle: heterotetramer structure of kluyveromyces lactis cse4,h4
86d1zbra1
not modelled 5.2 14
Fold:Pentein, beta/alpha-propeller
Superfamily:Pentein
Family:Porphyromonas-type peptidylarginine deiminase
87c4xb6D_
not modelled 5.2 15
PDB header:transferase
Chain: D: PDB Molecule:alpha-d-ribose 1-methylphosphonate 5-phosphate c-p lyase;
PDBTitle: structure of the e. coli c-p lyase core complex
88c4k8nF_
not modelled 5.1 17
PDB header:lipid transport
Chain: F: PDB Molecule:glycolipid transfer protein domain-containing protein 1;
PDBTitle: crystal structure of human ceramide-1-phosphate transfer protein2 (cptp) in complex with 18:1 ceramide-1-phosphate (18:1-c1p)
89c3hx8A_
not modelled 5.1 27
PDB header:isomerase
Chain: A: PDB Molecule:putative ketosteroid isomerase;
PDBTitle: crystal structure of putative ketosteroid isomerase (np_103587.1) from2 mesorhizobium loti at 1.45 a resolution
90c4ja0A_
not modelled 5.1 10
PDB header:protein binding
Chain: A: PDB Molecule:phosphoribosylaminoimidazole carboxylase;
PDBTitle: crystal structure of the invertebrate bi-functional purine2 biosynthesis enzyme paics at 2.8 a resolution

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Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below