1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	S	F	A	H	P	G	T	R	G	L	S	T	V	F	G	L	M	M	V	G	S	A	A	V	G	S	H	G	L	A	V	V	V	G	L	A	A	V	I	A	V	G	V	A	A	V	F	R	L	A	A	T	L	A	V	V	L	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?															?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	V	M	I	V	V	S	G	P	T	H	V	L	A	A	L	S	G	F	C	A	A	V	Y	L	V	C	R	Y	G	A	G	V	V	A	G	S	W	P	T	T	V	A	A	V	G	F	T	F	A	G	L	A	A	T	S	F	P	L	Q
Secondary structure
SS confidence
Disorder																																	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.
Sequence		V	P	W	L	P	L	A	A	P	L	A	V	L	A	T	Y	V	L	A	T	R	P	F	S	R
Secondary structure
SS confidence
Disorder																					?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 16%) Alpha helix ( 81%) Beta strand ( 0%) TM helix ( 61%) (View membrane topology prediction)

Rank Aligned region

PDB 2l5b chain A Region: 115 - 141 Aligned: 27 Modelled: 27 Confidence: 31.7% Identity: 41% PDB header:apoptosis Chain: A: PDB Molecule:activator of apoptosis harakiri; PDBTitle: solution structure of the transmembrane domain of bcl-2 member2 harakiri in micelles Phyre2 PDB 3kys chain B Region: 118 - 123 Aligned: 6 Modelled: 6 Confidence: 8.3% Identity: 50% PDB header:transcription/protein binding Chain: B: PDB Molecule:65 kda yes-associated protein; PDBTitle: crystal structure of human yap and tead complex Phyre2 PDB 6cn0 chain B Region: 118 - 127 Aligned: 10 Modelled: 10 Confidence: 8.2% Identity: 30% PDB header:transferase Chain: B: PDB Molecule:16s rrna (guanine(1405)-n(7))-methyltransferase; PDBTitle: 2.95 angstrom crystal structure of 16s rrna methylase from proteus2 mirabilis Phyre2 PDB 2loq chain A Region: 99 - 117 Aligned: 19 Modelled: 19 Confidence: 8.1% Identity: 42% PDB header:membrane protein Chain: A: PDB Molecule:interferon alpha-inducible protein 27-like protein 1; PDBTitle: backbone structure of human membrane protein fam14b (interferon alpha-2 inducible protein 27-like protein 1) Phyre2 PDB 1sdi chain A Region: 75 - 86 Aligned: 12 Modelled: 12 Confidence: 6.6% Identity: 50% Fold: YcfC-like Superfamily: YcfC-like Family: YcfC-like Phyre2 PDB 2e74 chain F domain 1 Region: 15 - 22 Aligned: 8 Modelled: 8 Confidence: 5.8% Identity: 63% Fold: Single transmembrane helix Superfamily: PetM subunit of the cytochrome b6f complex Family: PetM subunit of the cytochrome b6f complex Phyre2 PDB 3eip chain A Region: 115 - 129 Aligned: 15 Modelled: 15 Confidence: 5.7% Identity: 33% Fold: FKBP-like Superfamily: Colicin E3 immunity protein Family: Colicin E3 immunity protein Phyre2 1 c2l5bA_ 2 c3kysB_ 3 c6cn0B_ 4 c2loqA_ 5 d1sdia_ 6 d2e74f1 7 d3eipa_