Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD3163c_(-)_3531639_3532910
DateThu Aug 8 16:20:35 BST 2019
Unique Job IDd9e7d1c983e28df1
SequenceVIQTCEVELR ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:40.415 Y:39.865 Z:36.470
Model (left) based on template c6nmiE_
Top template information
PDB header:transcription
Chain: E: PDB Molecule:general transcription factor iih subunit 2, p44;
PDBTitle: cryo-em structure of the human tfiih core complex
Confidence and coverage
Confidence: 97.9% Coverage: 31%
130 residues ( 31% of your sequence) have been modelled with 97.9% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
196 residues ( 46%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
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Sequence analysis 

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Secondary structure and disorder prediction [Show] 

Domain analysis [Show] 

Detailed template information [Hide] 

 

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Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c6nmiE_
97.9 12
PDB header:transcription
Chain: E: PDB Molecule:general transcription factor iih subunit 2, p44;
PDBTitle: cryo-em structure of the human tfiih core complex
2c4fx5A_
97.8 13
PDB header:blood clotting
Chain: A: PDB Molecule:von willebrand factor type a;
PDBTitle: von willebrand factor type a from catenulispora acidiphila
3c5oqj6_
97.7 12
PDB header:transcription
Chain: 6: PDB Molecule:suppressor of stem-loop protein 1;
PDBTitle: structure of yeast transcription pre-initiation complex with tfiih
4c6o9l6_
97.7 14
PDB header:transcription/dna
Chain: 6: PDB Molecule:general transcription factor iih subunit 2;
PDBTitle: human holo-pic in the closed state
5d1jeyb2
97.6 14
Fold:vWA-like
Superfamily:vWA-like
Family:Ku80 subunit N-terminal domain
6c4b4tW_
97.6 18
PDB header:hydrolase
Chain: W: PDB Molecule:26s proteasome regulatory subunit rpn10;
PDBTitle: near-atomic resolution structural model of the yeast 26s proteasome
7d1yvra2
97.4 10
Fold:vWA-like
Superfamily:vWA-like
Family:RoRNP C-terminal domain-like
8c4rckB_
97.3 17
PDB header:membrane protein
Chain: B: PDB Molecule:hypothetical membrane spanning protein;
PDBTitle: crystal structure of uncharacterized membrane spanning protein from2 vibrio fischeri
9c2x31F_
97.3 13
PDB header:ligase
Chain: F: PDB Molecule:magnesium-chelatase 60 kda subunit;
PDBTitle: modelling of the complex between subunits bchi and bchd of magnesium2 chelatase based on single-particle cryo-em reconstruction at 7.5 ang
10c3ibsA_
97.2 15
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:conserved hypothetical protein batb;
PDBTitle: crystal structure of conserved hypothetical protein batb from2 bacteroides thetaiotaomicron
11c2iueA_
96.8 14
PDB header:membrane protein
Chain: A: PDB Molecule:pactolus i-domain;
PDBTitle: pactolus i-domain: functional switching of the rossmann2 fold
12d1jeya2
96.8 14
Fold:vWA-like
Superfamily:vWA-like
Family:Ku70 subunit N-terminal domain
13c5a8jA_
96.7 13
PDB header:transcription
Chain: A: PDB Molecule:vwa2;
PDBTitle: crystal structure of the arnb paralog vwa2 from2 sulfolobus acidocaldarius
14c4okuA_
96.6 15
PDB header:cell adhesion
Chain: A: PDB Molecule:micronemal protein mic2;
PDBTitle: structure of toxoplasma gondii promic2
15c5gjqW_
96.5 15
PDB header:hydrolase
Chain: W: PDB Molecule:26s proteasome non-atpase regulatory subunit 4;
PDBTitle: structure of the human 26s proteasome bound to usp14-ubal
16c2b2xB_
96.3 15
PDB header:immune system
Chain: B: PDB Molecule:integrin alpha-1;
PDBTitle: vla1 rdeltah i-domain complexed with a quadruple mutant of the aqc22 fab
17c2i6sA_
96.3 10
PDB header:hydrolase
Chain: A: PDB Molecule:complement c2a fragment;
PDBTitle: complement component c2a
18c4cnbA_
96.2 15
PDB header:structural protein
Chain: A: PDB Molecule:proximal thread matrix protein 1;
PDBTitle: structure of proximal thread matrix protein 1 (ptmp1) from the2 mussel byssus - crystal form 2
19c2nvoA_
96.2 12
PDB header:rna binding protein
Chain: A: PDB Molecule:ro sixty-related protein, rsr;
PDBTitle: crystal structure of deinococcus radiodurans ro (rsr) protein
20c6fpzA_
96.1 13
PDB header:structural protein
Chain: A: PDB Molecule:inter-alpha-trypsin inhibitor heavy chain h1;
PDBTitle: inter-alpha-inhibitor heavy chain 1, d298a
21c2ok5A_
not modelled 95.9 12
PDB header:hydrolase
Chain: A: PDB Molecule:complement factor b;
PDBTitle: human complement factor b
22c1jeyB_
not modelled 95.8 14
PDB header:dna binding protein/dna
Chain: B: PDB Molecule:ku80;
PDBTitle: crystal structure of the ku heterodimer bound to dna
23c3n2nC_
not modelled 95.7 15
PDB header:toxin receptor
Chain: C: PDB Molecule:anthrax toxin receptor 1;
PDBTitle: the crystal structure of tumor endothelial marker 8 (tem8)2 extracellular domain
24c4wfqA_
not modelled 95.4 15
PDB header:transcription
Chain: A: PDB Molecule:suppressor of stem-loop protein 1;
PDBTitle: crystal structure of tfiih subunit
25c2x5nA_
not modelled 95.4 15
PDB header:nuclear protein
Chain: A: PDB Molecule:26s proteasome regulatory subunit rpn10;
PDBTitle: crystal structure of the sprpn10 vwa domain
26c1rs0A_
not modelled 94.8 12
PDB header:hydrolase
Chain: A: PDB Molecule:complement factor b;
PDBTitle: crystal structure analysis of the bb segment of factor b2 complexed with di-isopropyl-phosphate (dip)
27c4hqnB_
not modelled 94.7 13
PDB header:cell adhesion
Chain: B: PDB Molecule:sporozoite surface protein 2;
PDBTitle: crystal structure of manganese-loaded plasmodium vivax trap protein
28c2xggB_
not modelled 94.1 15
PDB header:hydrolase
Chain: B: PDB Molecule:microneme protein 2;
PDBTitle: structure of toxoplasma gondii micronemal protein 2 a_i2 domain
29c5e6rA_
not modelled 94.0 13
PDB header:cell adhesion
Chain: A: PDB Molecule:integrin alpha-l;
PDBTitle: structures of leukocyte integrin alb2: the ai domain, the headpiece,2 and the pocket for the internal ligand
30d2ok5a1
not modelled 93.5 12
Fold:vWA-like
Superfamily:vWA-like
Family:Integrin A (or I) domain
31d1shux_
not modelled 93.0 16
Fold:vWA-like
Superfamily:vWA-like
Family:Integrin A (or I) domain
32c5gjvF_
not modelled 91.9 15
PDB header:membrane protein
Chain: F: PDB Molecule:voltage-dependent calcium channel subunit alpha-2/delta-1;
PDBTitle: structure of the mammalian voltage-gated calcium channel cav1.12 complex at near atomic resolution
33c5iy70_
not modelled 91.8 11
PDB header:transcription, transferase/dna
Chain: 0: PDB Molecule:general transcription factor iih subunit 2;
PDBTitle: human holo-pic in the open state
34c3txaA_
not modelled 90.1 18
PDB header:cell adhesion
Chain: A: PDB Molecule:cell wall surface anchor family protein;
PDBTitle: structural analysis of adhesive tip pilin, gbs104 from group b2 streptococcus agalactiae
35c5y58E_
not modelled 90.0 10
PDB header:rna binding protein
Chain: E: PDB Molecule:atp-dependent dna helicase ii subunit 1;
PDBTitle: crystal structure of ku70/80 and tlc1
36c3jbrF_
not modelled 89.1 10
PDB header:membrane protein
Chain: F: PDB Molecule:voltage-dependent calcium channel subunit alpha-2/delta-1;
PDBTitle: cryo-em structure of the rabbit voltage-gated calcium channel cav1.12 complex at 4.2 angstrom
37d1v7pc_
not modelled 88.7 16
Fold:vWA-like
Superfamily:vWA-like
Family:Integrin A (or I) domain
38d1ck4a_
not modelled 88.1 12
Fold:vWA-like
Superfamily:vWA-like
Family:Integrin A (or I) domain
39d1pd0a3
not modelled 87.1 15
Fold:vWA-like
Superfamily:vWA-like
Family:Trunk domain of Sec23/24
40c4hqfA_
not modelled 86.5 15
PDB header:cell adhesion
Chain: A: PDB Molecule:thrombospondin-related anonymous protein, trap;
PDBTitle: crystal structure of plasmodium falciparum trap, i4 form
41d1u0oc1
not modelled 83.7 12
Fold:vWA-like
Superfamily:vWA-like
Family:Integrin A (or I) domain
42d1pt6a_
not modelled 82.5 13
Fold:vWA-like
Superfamily:vWA-like
Family:Integrin A (or I) domain
43c5y59B_
not modelled 81.7 10
PDB header:protein binding
Chain: B: PDB Molecule:atp-dependent dna helicase ii subunit 2;
PDBTitle: crystal structure of ku80 and sir4
44c3tw0D_
not modelled 81.2 20
PDB header:cell adhesion
Chain: D: PDB Molecule:cell wall surface anchor family protein;
PDBTitle: structural analysis of adhesive tip pilin, gbs104 from group b2 streptococcus agalactiae
45d1n3ya_
not modelled 81.1 12
Fold:vWA-like
Superfamily:vWA-like
Family:Integrin A (or I) domain
46c1jeqA_
not modelled 80.9 13
PDB header:dna binding protein
Chain: A: PDB Molecule:ku70;
PDBTitle: crystal structure of the ku heterodimer
47c2kl6A_
not modelled 80.0 18
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: solution nmr structure of the cardb domain of pf1109 from2 pyrococcus furiosus. northeast structural genomics3 consortium target pfr193a
48d1q0pa_
not modelled 78.3 9
Fold:vWA-like
Superfamily:vWA-like
Family:Integrin A (or I) domain
49c6djpB_
not modelled 76.1 14
PDB header:membrane protein
Chain: B: PDB Molecule:integrin beta-8;
PDBTitle: integrin alpha-v beta-8 in complex with the fabs 8b8 and 68
50c1yvrA_
not modelled 75.5 11
PDB header:rna binding protein
Chain: A: PDB Molecule:60-kda ss-a/ro ribonucleoprotein;
PDBTitle: ro autoantigen
51d1w8oa1
not modelled 75.3 21
Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:E-set domains of sugar-utilizing enzymes
52d1atza_
not modelled 72.9 13
Fold:vWA-like
Superfamily:vWA-like
Family:Integrin A (or I) domain
53c3we7A_
not modelled 71.1 16
PDB header:hydrolase
Chain: A: PDB Molecule:putative uncharacterized protein ph0499;
PDBTitle: crystal structure of diacetylchitobiose deacetylase from pyrococcus2 horikoshii
54c3dfmA_
not modelled 71.1 15
PDB header:hydrolase
Chain: A: PDB Molecule:teicoplanin pseudoaglycone deacetylase orf2;
PDBTitle: the crystal structure of the zinc inhibited form of2 teicoplanin deacetylase orf2
55c3vi3D_
not modelled 71.1 17
PDB header:cell adhesion/immune system
Chain: D: PDB Molecule:integrin beta-1;
PDBTitle: crystal structure of alpha5beta1 integrin headpiece (ligand-free form)
56c4ihkA_
not modelled 68.7 16
PDB header:cell adhesion
Chain: A: PDB Molecule:collagen alpha3(vi);
PDBTitle: crystal structure of the collagen vi alpha3 n5 domain r1061q
57c6bxjA_
not modelled 66.9 12
PDB header:cell adhesion
Chain: A: PDB Molecule:chimera protein of integrin beta-3 and integrin alpha-l;
PDBTitle: structure of a single-chain beta3 integrin
58c5y58D_
not modelled 66.9 9
PDB header:rna binding protein
Chain: D: PDB Molecule:atp-dependent dna helicase ii subunit 2;
PDBTitle: crystal structure of ku70/80 and tlc1
59c3ragA_
not modelled 65.9 13
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of uncharacterized protein aaci_0196 from2 alicyclobacillus acidocaldarius subsp. acidocaldarius dsm 446
60c3v4pB_
not modelled 65.3 21
PDB header:cell adhesion
Chain: B: PDB Molecule:integrin beta-7;
PDBTitle: crystal structure of a4b7 headpiece complexed with fab act-1
61d1mjna_
not modelled 64.6 12
Fold:vWA-like
Superfamily:vWA-like
Family:Integrin A (or I) domain
62d1mf7a_
not modelled 62.8 11
Fold:vWA-like
Superfamily:vWA-like
Family:Integrin A (or I) domain
63c5bmoB_
not modelled 62.1 16
PDB header:hydrolase
Chain: B: PDB Molecule:putative uncharacterized protein lnmx;
PDBTitle: lnmx protein, a putative glcnac-pi de-n-acetylase from streptomyces2 atroolivaceus
64c5cgzA_
not modelled 61.0 9
PDB header:lyase
Chain: A: PDB Molecule:4-oxalmesaconate hydratase;
PDBTitle: crystal structure of galb, the 4-carboxy-2-hydroxymuconate hydratase,2 from pseuodomonas putida kt2440
65d1cf1a2
not modelled 60.7 16
Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Arrestin/Vps26-like
66c2kutA_
not modelled 59.9 21
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: solution structure of gmr58a from geobacter metallireducens.2 northeast structural genomics consortium target gmr58a
67d1ayra2
not modelled 59.1 16
Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Arrestin/Vps26-like
68d1tyeb2
not modelled 58.4 13
Fold:vWA-like
Superfamily:vWA-like
Family:Integrin A (or I) domain
69d1uana_
not modelled 57.9 10
Fold:LmbE-like
Superfamily:LmbE-like
Family:LmbE-like
70c4um9D_
not modelled 53.2 17
PDB header:immune system
Chain: D: PDB Molecule:integrin beta-6;
PDBTitle: crystal structure of alpha v beta 6 with peptide
71d1g4ma2
not modelled 53.2 16
Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Arrestin/Vps26-like
72c6adqP_
not modelled 51.1 25
PDB header:electron transport
Chain: P: PDB Molecule:prokaryotic respiratory supercomplex associate factor 1
PDBTitle: respiratory complex ciii2civ2sod2 from mycobacterium smegmatis
73c3gxbB_
not modelled 50.3 13
PDB header:cell adhesion
Chain: B: PDB Molecule:von willebrand factor;
PDBTitle: crystal structure of vwf a2 domain
74c3dfiA_
not modelled 49.6 15
PDB header:hydrolase
Chain: A: PDB Molecule:pseudoaglycone deacetylase dbv21;
PDBTitle: the crystal structure of antimicrobial reagent a40926 pseudoaglycone2 deacetylase dbv21
75c2l0dA_
not modelled 48.2 16
PDB header:cell adhesion
Chain: A: PDB Molecule:cell surface protein;
PDBTitle: solution nmr structure of putative cell surface protein ma_4588 (272-2 376 domain) from methanosarcina acetivorans, northeast structural3 genomics consortium target mvr254a
76c2ixdB_
not modelled 46.8 18
PDB header:hydrolase
Chain: B: PDB Molecule:lmbe-related protein;
PDBTitle: crystal structure of the putative deacetylase bc1534 from bacillus2 cereus
77d1ijba_
not modelled 46.1 12
Fold:vWA-like
Superfamily:vWA-like
Family:Integrin A (or I) domain
78c6bxfA_
not modelled 44.8 12
PDB header:cell adhesion
Chain: A: PDB Molecule:chimera protein of integrin beta-3 and integrin alpha-l;
PDBTitle: crystal structure of an extended b3 integrin l33
79d1q74a_
not modelled 43.8 13
Fold:LmbE-like
Superfamily:LmbE-like
Family:LmbE-like
80c1u8cB_
not modelled 41.3 15
PDB header:cell adhesion
Chain: B: PDB Molecule:integrin beta-3;
PDBTitle: a novel adaptation of the integrin psi domain revealed from its2 crystal structure
81c1q7tA_
not modelled 37.2 14
PDB header:hydrolase
Chain: A: PDB Molecule:hypothetical protein rv1170;
PDBTitle: rv1170 (mshb) from mycobacterium tuberculosis
82c1cf1B_
not modelled 34.0 16
PDB header:structural protein
Chain: B: PDB Molecule:protein (arrestin);
PDBTitle: arrestin from bovine rod outer segments
83c5z87B_
not modelled 33.4 14
PDB header:hydrolase
Chain: B: PDB Molecule:emgh1;
PDBTitle: structural of a novel b-glucosidase emgh1 at 2.3 angstrom from2 erythrobacter marinus
84c1jsyA_
not modelled 32.2 16
PDB header:signaling protein
Chain: A: PDB Molecule:bovine arrestin-2 (full length);
PDBTitle: crystal structure of bovine arrestin-2
85d1h70a_
not modelled 31.9 22
Fold:Pentein, beta/alpha-propeller
Superfamily:Pentein
Family:Dimethylarginine dimethylaminohydrolase DDAH
86c1ayrA_
not modelled 29.3 16
PDB header:sensory transduction
Chain: A: PDB Molecule:arrestin;
PDBTitle: arrestin from bovine rod outer segments
87c1g4mA_
not modelled 29.0 16
PDB header:signaling protein
Chain: A: PDB Molecule:beta-arrestin1;
PDBTitle: crystal structure of bovine beta-arrestin 1
88c2wfbA_
not modelled 27.6 9
PDB header:biosynthetic protein
Chain: A: PDB Molecule:putative uncharacterized protein orp;
PDBTitle: high resolution structure of the apo form of the orange2 protein (orp) from desulfovibrio gigas
89c1sujA_
not modelled 27.6 10
PDB header:signaling protein
Chain: A: PDB Molecule:cone arrestin;
PDBTitle: x-ray crystal structure of ambystoma tigrinum cone arrestin
90c4zlpB_
not modelled 24.1 12
PDB header:transcription
Chain: B: PDB Molecule:neurogenic locus notch homolog protein 3;
PDBTitle: crystal structure of notch3 negative regulatory region
91d2iela1
not modelled 22.7 20
Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:Universal stress protein-like
92c5jp0A_
not modelled 22.0 13
PDB header:hydrolase
Chain: A: PDB Molecule:beta-glucosidase bogh3b;
PDBTitle: bacteroides ovatus xyloglucan pul gh3b with bound glucose
93d1uc8a1
not modelled 21.6 10
Fold:PreATP-grasp domain
Superfamily:PreATP-grasp domain
Family:Lysine biosynthesis enzyme LysX, N-terminal domain
94d1im5a_
not modelled 21.4 15
Fold:Isochorismatase-like hydrolases
Superfamily:Isochorismatase-like hydrolases
Family:Isochorismatase-like hydrolases
95c5z9sB_
not modelled 21.0 12
PDB header:hydrolase
Chain: B: PDB Molecule:glycosyl hydrolase family 3 protein;
PDBTitle: functional and structural characterization of a beta-glucosidase2 involved in saponin metabolism from intestinal bacteria
96c1l9mB_
not modelled 20.7 13
PDB header:transferase
Chain: B: PDB Molecule:protein-glutamine glutamyltransferase e3;
PDBTitle: three-dimensional structure of the human transglutaminase 32 enzyme: binding of calcium ions change structure for3 activation
97c4i3gB_
not modelled 20.4 16
PDB header:hydrolase
Chain: B: PDB Molecule:beta-glucosidase;
PDBTitle: crystal structure of desr, a beta-glucosidase from streptomyces2 venezuelae in complex with d-glucose.
98c5k2mG_
not modelled 19.7 16
PDB header:biosynthetic protein
Chain: G: PDB Molecule:rimk-related lysine biosynthesis protein;
PDBTitle: bifunctional lysx/argx from thermococcus kodakarensis with lysw-gamma-2 aaa
99d1rl2a2
not modelled 19.3 16
Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:Cold shock DNA-binding domain-like

Binding site prediction 

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Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below