1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	P	V	T	D	E	Q	V	E	L	V	R	S	L	V	A	A	I	P	L	G	R	V	S	T	Y	G	D	I	A	A	L	T	G	L	S	S	P	R	I	V	G	W	I	M	R	T	D	S	S	D	L	P	W	H	R	V	I	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.
Sequence		A	S	G	R	P	A	Q	H	L	A	T	R	Q	L	E	L	L	R	A	E	G	V	L	S	V	D	G	R	V	A	L	S	E	I	R	Y	E	F	P	P	G
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?																?												?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 17%) Alpha helix ( 46%) Beta strand ( 14%)

Rank Aligned region

PDB 3gx4 chain X Region: 6 - 98 Aligned: 93 Modelled: 93 Confidence: 100.0% Identity: 40% PDB header:dna binding protein/dna Chain: X: PDB Molecule:alkyltransferase-like protein 1; PDBTitle: crystal structure analysis of s. pombe atl in complex with dna Phyre2 PDB 2kim chain A Region: 6 - 98 Aligned: 93 Modelled: 93 Confidence: 100.0% Identity: 33% PDB header:transferase Chain: A: PDB Molecule:o6-methylguanine-dna methyltransferase; PDBTitle: 1.7-mm microcryoprobe solution nmr structure of an o6-methylguanine2 dna methyltransferase family protein from vibrio parahaemolyticus.3 northeast structural genomics consortium target vpr247. Phyre2 PDB 1sfe chain A Region: 1 - 81 Aligned: 81 Modelled: 81 Confidence: 100.0% Identity: 25% PDB header:dna-binding protein Chain: A: PDB Molecule:ada o6-methylguanine-dna methyltransferase; PDBTitle: ada o6-methylguanine-dna methyltransferase from escherichia coli Phyre2 PDB 4bhc chain A Region: 1 - 87 Aligned: 87 Modelled: 87 Confidence: 100.0% Identity: 28% PDB header:transferase Chain: A: PDB Molecule:methylated-dna--protein-cysteine methyltransferase; PDBTitle: crystal structure of the m. tuberculosis o6-methylguanine2 methyltransferase r37l variant Phyre2 PDB 1sfe chain A domain 1 Region: 5 - 82 Aligned: 78 Modelled: 78 Confidence: 100.0% Identity: 26% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Methylated DNA-protein cysteine methyltransferase, C-terminal domain Family: Methylated DNA-protein cysteine methyltransferase, C-terminal domain Phyre2 PDB 1t39 chain A Region: 5 - 81 Aligned: 77 Modelled: 77 Confidence: 100.0% Identity: 30% PDB header:transferase/dna Chain: A: PDB Molecule:methylated-dna--protein-cysteine PDBTitle: human o6-alkylguanine-dna alkyltransferase covalently2 crosslinked to dna Phyre2 PDB 1qnt chain A domain 1 Region: 6 - 84 Aligned: 79 Modelled: 79 Confidence: 100.0% Identity: 29% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Methylated DNA-protein cysteine methyltransferase, C-terminal domain Family: Methylated DNA-protein cysteine methyltransferase, C-terminal domain Phyre2 PDB 4zye chain A Region: 1 - 86 Aligned: 84 Modelled: 86 Confidence: 100.0% Identity: 33% PDB header:transferase Chain: A: PDB Molecule:methylated-dna--protein-cysteine methyltransferase; PDBTitle: crystal structure of sulfolobus solfataricus o6-methylguanine2 methyltransferase Phyre2 PDB 2g7h chain A Region: 1 - 90 Aligned: 88 Modelled: 90 Confidence: 100.0% Identity: 26% PDB header:transferase Chain: A: PDB Molecule:methylated-dna--protein-cysteine PDBTitle: structure of an o6-methylguanine dna methyltransferase from2 methanococcus jannaschii (mj1529) Phyre2 PDB 1mgt chain A Region: 3 - 82 Aligned: 78 Modelled: 80 Confidence: 100.0% Identity: 31% PDB header:transferase Chain: A: PDB Molecule:protein (o6-methylguanine-dna methyltransferase); PDBTitle: crystal structure of o6-methylguanine-dna methyltransferase from2 hyperthermophilic archaeon pyrococcus kodakaraensis strain kod1 Phyre2 PDB 1mgt chain A domain 1 Region: 6 - 82 Aligned: 76 Modelled: 77 Confidence: 99.9% Identity: 32% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Methylated DNA-protein cysteine methyltransferase, C-terminal domain Family: Methylated DNA-protein cysteine methyltransferase, C-terminal domain Phyre2 PDB 1wrj chain A Region: 3 - 84 Aligned: 80 Modelled: 82 Confidence: 99.9% Identity: 29% PDB header:transferase Chain: A: PDB Molecule:methylated-dna--protein-cysteine PDBTitle: crystal structure of o6-methylguanine methyltransferase2 from sulfolobus tokodaii Phyre2 PDB 1qgp chain A Region: 4 - 62 Aligned: 59 Modelled: 58 Confidence: 78.0% Identity: 12% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Z-DNA binding domain Phyre2 PDB 2cyy chain A domain 1 Region: 6 - 48 Aligned: 39 Modelled: 43 Confidence: 43.6% Identity: 18% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Lrp/AsnC-like transcriptional regulator N-terminal domain Phyre2 PDB 1xmk chain A domain 1 Region: 7 - 46 Aligned: 37 Modelled: 40 Confidence: 42.4% Identity: 19% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Z-DNA binding domain Phyre2 PDB 1qbj chain C Region: 4 - 46 Aligned: 42 Modelled: 43 Confidence: 28.5% Identity: 12% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Z-DNA binding domain Phyre2 PDB 2gxb chain A domain 1 Region: 10 - 58 Aligned: 49 Modelled: 48 Confidence: 27.3% Identity: 12% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Z-DNA binding domain Phyre2 PDB 1zgw chain A Region: 1 - 48 Aligned: 47 Modelled: 48 Confidence: 21.2% Identity: 11% PDB header:transcription regulator/dna Chain: A: PDB Molecule:ada polyprotein; PDBTitle: nmr structure of e. coli ada protein in complex with dna Phyre2 PDB 3i4p chain A Region: 5 - 48 Aligned: 40 Modelled: 43 Confidence: 20.9% Identity: 15% PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator, asnc family; PDBTitle: crystal structure of asnc family transcriptional regulator from2 agrobacterium tumefaciens Phyre2 PDB 4czd chain A Region: 6 - 48 Aligned: 42 Modelled: 43 Confidence: 20.4% Identity: 14% PDB header:lyase Chain: A: PDB Molecule:putative transcriptional regulator, asnc family; PDBTitle: sirohaem decarboxylase ahba/b - an enzyme with structural homology2 to the lrp/asnc transcription factor family that is part of the3 alternative haem biosynthesis pathway. Phyre2 1 c3gx4X_ 2 c2kimA_ 3 c1sfeA_ 4 c4bhcA_ 5 d1sfea1 6 c1t39A_ 7 d1qnta1 8 c4zyeA_ 9 c2g7hA_ 10 c1mgtA_ 11 d1mgta1 12 c1wrjA_ 13 d1qgpa_ 14 d2cyya1 15 d1xmka1 16 d1qbjc_ 17 d2gxba1 18 c1zgwA_ 19 c3i4pA_ 20 c4czdA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91