1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	G	V	R	N	H	R	L	L	L	L	R	H	G	E	T	A	W	S	T	L	G	R	H	T	G	G	T	E	V	E	L	T	D	T	G	R	T	Q	A	E	L	A	G	Q	L	L	G	E	L	E	L	D	D	P	I	V	I	C	S
Secondary structure
SS confidence
Disorder		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	R	R	R	T	L	D	T	A	K	L	A	G	L	T	V	N	E	V	T	G	L	L	A	E	W	D	Y	G	S	Y	E	G	L	T	T	P	Q	I	R	E	S	E	P	D	W	L	V	W	T	H	G	C	P	A	G	E	S	V	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		Q	V	N	D	R	A	D	S	A	V	A	L	A	L	E	H	M	S	S	R	D	V	L	F	V	S	H	G	H	F	S	R	A	V	I	T	R	W	V	Q	L	P	L	A	E	G	S	R	F	A	M	P	T	A	S	I	G	I	C	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.
Sequence		F	E	H	G	V	R	Q	L	A	V	L	G	L	T	G	H	P	Q	P	I	A	A	G
Secondary structure
SS confidence
Disorder																			?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 5%) Alpha helix ( 42%) Beta strand ( 15%)

Rank Aligned region

PDB 2a6p chain A Region: 4 - 196 Aligned: 193 Modelled: 193 Confidence: 100.0% Identity: 100% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:possible phosphoglycerate mutase gpm2; PDBTitle: structure solution to 2.2 angstrom and functional characterisation of2 the open reading frame rv3214 from mycobacterium tuberculosis Phyre2 PDB 4ij5 chain B Region: 6 - 202 Aligned: 195 Modelled: 197 Confidence: 100.0% Identity: 26% PDB header:hydrolase Chain: B: PDB Molecule:phosphoserine phosphatase 1; PDBTitle: crystal structure of a novel-type phosphoserine phosphatase from2 hydrogenobacter thermophilus tk-6 Phyre2 PDB 5zkk chain A Region: 6 - 197 Aligned: 189 Modelled: 189 Confidence: 100.0% Identity: 25% PDB header:hydrolase Chain: A: PDB Molecule:phosphoglycerate mutase family protein, putative; PDBTitle: crystal structure of phosphoserine phosphatase from entamoeba2 histolytica Phyre2 PDB 4emb chain D Region: 7 - 198 Aligned: 192 Modelled: 192 Confidence: 100.0% Identity: 26% PDB header:isomerase Chain: D: PDB Molecule:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; PDBTitle: crystal structure of a phosphoglycerate mutase gpma from borrelia2 burgdorferi b31 Phyre2 PDB 1h2e chain A Region: 6 - 201 Aligned: 194 Modelled: 196 Confidence: 100.0% Identity: 27% Fold: Phosphoglycerate mutase-like Superfamily: Phosphoglycerate mutase-like Family: Cofactor-dependent phosphoglycerate mutase Phyre2 PDB 1e58 chain A Region: 6 - 192 Aligned: 187 Modelled: 187 Confidence: 100.0% Identity: 27% Fold: Phosphoglycerate mutase-like Superfamily: Phosphoglycerate mutase-like Family: Cofactor-dependent phosphoglycerate mutase Phyre2 PDB 1xq9 chain A Region: 3 - 200 Aligned: 195 Modelled: 198 Confidence: 100.0% Identity: 24% Fold: Phosphoglycerate mutase-like Superfamily: Phosphoglycerate mutase-like Family: Cofactor-dependent phosphoglycerate mutase Phyre2 PDB 1yjx chain D Region: 4 - 198 Aligned: 195 Modelled: 195 Confidence: 100.0% Identity: 23% PDB header:isomerase, hydrolase Chain: D: PDB Molecule:phosphoglycerate mutase 1; PDBTitle: crystal structure of human b type phosphoglycerate mutase Phyre2 PDB 6e4b chain C Region: 5 - 196 Aligned: 190 Modelled: 192 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: C: PDB Molecule:adenosylcobalamin/alpha-ribazole phosphatase; PDBTitle: the crystal structure of a putative alpha-ribazole-5'-p phosphatase2 from escherichia coli str. k-12 substr. mg1655 Phyre2 PDB 1rii chain A Region: 4 - 203 Aligned: 200 Modelled: 200 Confidence: 100.0% Identity: 31% Fold: Phosphoglycerate mutase-like Superfamily: Phosphoglycerate mutase-like Family: Cofactor-dependent phosphoglycerate mutase Phyre2 PDB 3r7a chain A Region: 1 - 197 Aligned: 189 Modelled: 191 Confidence: 100.0% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:phosphoglycerate mutase, putative; PDBTitle: crystal structure of phosphoglycerate mutase from bacillus anthracis2 str. sterne Phyre2 PDB 5vve chain A Region: 6 - 195 Aligned: 190 Modelled: 190 Confidence: 100.0% Identity: 24% PDB header:isomerase Chain: A: PDB Molecule:phosphoglycerate mutase; PDBTitle: crystal structure of phosphoglycerate mutase from naegleria fowleri Phyre2 PDB 1qhf chain A Region: 7 - 203 Aligned: 194 Modelled: 197 Confidence: 100.0% Identity: 26% Fold: Phosphoglycerate mutase-like Superfamily: Phosphoglycerate mutase-like Family: Cofactor-dependent phosphoglycerate mutase Phyre2 PDB 4pz9 chain B Region: 6 - 195 Aligned: 185 Modelled: 190 Confidence: 100.0% Identity: 32% PDB header:hydrolase Chain: B: PDB Molecule:glucosyl-3-phosphoglycerate phosphatase; PDBTitle: the native structure of mycobacterial glucosyl-3-phosphoglycerate2 phosphatase rv2419c Phyre2 PDB 3ezn chain B Region: 6 - 191 Aligned: 186 Modelled: 186 Confidence: 100.0% Identity: 25% PDB header:isomerase Chain: B: PDB Molecule:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; PDBTitle: crystal structure of phosphoglyceromutase from burkholderia2 pseudomallei 1710b Phyre2 PDB 3d8h chain B Region: 4 - 191 Aligned: 188 Modelled: 188 Confidence: 100.0% Identity: 24% PDB header:isomerase Chain: B: PDB Molecule:glycolytic phosphoglycerate mutase; PDBTitle: crystal structure of phosphoglycerate mutase from cryptosporidium2 parvum, cgd7_4270 Phyre2 PDB 5um0 chain A Region: 5 - 191 Aligned: 187 Modelled: 187 Confidence: 100.0% Identity: 25% PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; PDBTitle: crystal structure of 2,3-bisphosphoglycerate-dependent2 phosphoglycerate mutase from neisseria gonorrhoeae Phyre2 PDB 2yn0 chain A Region: 3 - 199 Aligned: 195 Modelled: 196 Confidence: 100.0% Identity: 18% PDB header:transcription Chain: A: PDB Molecule:transcription factor tau 55 kda subunit; PDBTitle: tau55 histidine phosphatase domain Phyre2 PDB 1fzt chain A Region: 4 - 193 Aligned: 190 Modelled: 190 Confidence: 100.0% Identity: 25% Fold: Phosphoglycerate mutase-like Superfamily: Phosphoglycerate mutase-like Family: Cofactor-dependent phosphoglycerate mutase Phyre2 PDB 2hhj chain A domain 1 Region: 5 - 184 Aligned: 179 Modelled: 180 Confidence: 100.0% Identity: 25% Fold: Phosphoglycerate mutase-like Superfamily: Phosphoglycerate mutase-like Family: Cofactor-dependent phosphoglycerate mutase Phyre2 1 c2a6pA_ 2 c4ij5B_ 3 c5zkkA_ 4 c4embD_ 5 d1h2ea_ 6 d1e58a_ 7 d1xq9a_ 8 c1yjxD_ 9 c6e4bC_ 10 d1riia_ 11 c3r7aA_ 12 c5vveA_ 13 d1qhfa_ 14 c4pz9B_ 15 c3eznB_ 16 c3d8hB_ 17 c5um0A_ 18 c2yn0A_ 19 d1fzta_ 20 d2hhja1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99