1

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10

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20

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30

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40

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50

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60

Sequence

V

R

R

S

A

S

T

C

G

W

K

T

P

T

R

R

G

T

S

R

P

S

D

S

K

T

L

I

L

E

L

P

D

E

R

A

V

A

I

V

P

V

P

S

K

L

S

L

K

A

A

G

G

P

R

G

A

Q

S

G

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

Disorder confidence

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Sequence

H

G

Secondary structure

SS confidence

Disorder

?

?

Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 63%) Alpha helix ( 0%) Beta strand ( 27%)

Rank Aligned region

PDB 3mem chain A Region: 25 - 50 Aligned: 26 Modelled: 24 Confidence: 37.6% Identity: 23% PDB header:signaling protein Chain: A: PDB Molecule:putative signal transduction protein; PDBTitle: crystal structure of a putative signal transduction protein2 (maqu_0641) from marinobacter aquaeolei vt8 at 2.25 a resolution Phyre2 PDB 1dce chain A domain 2 Region: 7 - 32 Aligned: 22 Modelled: 26 Confidence: 25.7% Identity: 41% Fold: C2 domain-like Superfamily: Rab geranylgeranyltransferase alpha-subunit, insert domain Family: Rab geranylgeranyltransferase alpha-subunit, insert domain Phyre2 PDB 5iva chain B Region: 6 - 33 Aligned: 26 Modelled: 28 Confidence: 23.3% Identity: 15% PDB header:transport protein Chain: B: PDB Molecule:lps-assembly lipoprotein lpte; PDBTitle: the lps transporter lptde from pseudomonas aeruginosa, core complex Phyre2 PDB 2d46 chain A Region: 18 - 24 Aligned: 7 Modelled: 7 Confidence: 20.9% Identity: 100% PDB header:metal transport Chain: A: PDB Molecule:calcium channel, voltage-dependent, beta 4 PDBTitle: solution structure of the human beta4a-a domain Phyre2 PDB 3okr chain C Region: 35 - 54 Aligned: 19 Modelled: 20 Confidence: 15.5% Identity: 42% PDB header:transferase Chain: C: PDB Molecule:2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase; PDBTitle: structure of mtb apo 2-c-methyl-d-erythritol 4-phosphate2 cytidyltransferase (ispd) Phyre2 PDB 3cxb chain A Region: 41 - 54 Aligned: 14 Modelled: 14 Confidence: 13.3% Identity: 57% PDB header:signaling protein Chain: A: PDB Molecule:protein sifa; PDBTitle: crystal structure of sifa and skip Phyre2 PDB 1vki chain A Region: 24 - 50 Aligned: 27 Modelled: 27 Confidence: 11.6% Identity: 22% Fold: YbaK/ProRS associated domain Superfamily: YbaK/ProRS associated domain Family: YbaK/ProRS associated domain Phyre2 PDB 4lm6 chain A Region: 22 - 47 Aligned: 26 Modelled: 26 Confidence: 9.2% Identity: 42% PDB header:photosynthesis Chain: A: PDB Molecule:cryptophyte phycocyanin alpha chain; PDBTitle: light harvesting complex pc612 from the cryptophyte hemiselmis2 virescens m1635 Phyre2 PDB 3ng3 chain A Region: 42 - 55 Aligned: 14 Modelled: 14 Confidence: 7.7% Identity: 50% PDB header:lyase Chain: A: PDB Molecule:deoxyribose-phosphate aldolase; PDBTitle: crystal structure of deoxyribose phosphate aldolase from mycobacterium2 avium 104 in a schiff base with an unknown aldehyde Phyre2 PDB 6hm3 chain B Region: 21 - 33 Aligned: 13 Modelled: 13 Confidence: 7.5% Identity: 54% PDB header:cell cycle Chain: B: PDB Molecule:dna replication regulator sld3; PDBTitle: crystal structure of rad4 brct1,2 in complex with a sld32 phosphopeptide Phyre2 PDB 5dbu chain I Region: 42 - 55 Aligned: 14 Modelled: 14 Confidence: 7.4% Identity: 43% PDB header:lyase Chain: I: PDB Molecule:deoxyribose-phosphate aldolase; PDBTitle: crystal structure of 2-deoxyribose-5-phosphate aldolase (1-220) from2 streptococcus suis Phyre2 PDB 3ngj chain C Region: 42 - 55 Aligned: 14 Modelled: 14 Confidence: 7.0% Identity: 57% PDB header:lyase Chain: C: PDB Molecule:deoxyribose-phosphate aldolase; PDBTitle: crystal structure of a putative deoxyribose-phosphate aldolase from2 entamoeba histolytica Phyre2 PDB 4xbs chain A Region: 42 - 55 Aligned: 14 Modelled: 14 Confidence: 6.6% Identity: 43% PDB header:lyase Chain: A: PDB Molecule:deoxyribose-phosphate aldolase; PDBTitle: 2-deoxyribose-5-phosphate aldolase mutant - e78k Phyre2 PDB 1yk0 chain E Region: 56 - 62 Aligned: 7 Modelled: 7 Confidence: 6.5% Identity: 86% PDB header:hormone/growth factor receptor Chain: E: PDB Molecule:atrial natriuretic factor; PDBTitle: structure of natriuretic peptide receptor-c complexed with atrial2 natriuretic peptide Phyre2 PDB 1o0y chain A Region: 42 - 55 Aligned: 14 Modelled: 14 Confidence: 6.0% Identity: 43% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 1mzh chain A Region: 42 - 55 Aligned: 14 Modelled: 14 Confidence: 5.9% Identity: 36% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 1t34 chain H Region: 56 - 62 Aligned: 7 Modelled: 7 Confidence: 5.7% Identity: 86% PDB header:signaling protein,membrane protein Chain: H: PDB Molecule:atrial natriuretic peptide factor; PDBTitle: rotation mechanism for transmembrane signaling by the atrial2 natriuretic peptide receptor Phyre2 PDB 2glz chain A domain 1 Region: 28 - 47 Aligned: 20 Modelled: 20 Confidence: 5.6% Identity: 25% Fold: FwdE/GAPDH domain-like Superfamily: FwdE-like Family: FwdE-like Phyre2 PDB 4evu chain B Region: 28 - 44 Aligned: 17 Modelled: 17 Confidence: 5.2% Identity: 35% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative periplasmic protein ydgh; PDBTitle: crystal structure of c-terminal domain of putative periplasmic protein2 ydgh from s. enterica Phyre2 PDB 2cx5 chain B Region: 25 - 49 Aligned: 25 Modelled: 25 Confidence: 5.2% Identity: 20% PDB header:translation Chain: B: PDB Molecule:a putative trans-editing enzyme; PDBTitle: crystal structure of a putative trans-editing enzyme for2 prolyl trna synthetase Phyre2 1 c3memA_ 2 d1dcea2 3 c5ivaB_ 4 c2d46A_ 5 c3okrC_ 6 c3cxbA_ 7 d1vkia_ 8 c4lm6A_ 9 c3ng3A_ 10 c6hm3B_ 11 c5dbuI_ 12 c3ngjC_ 13 c4xbsA_ 14 c1yk0E_ 15 d1o0ya_ 16 d1mzha_ 17 c1t34H_ 18 d2glza1 19 c4evuB_ 20 c2cx5B_