1

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10

.

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20

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30

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40

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50

.

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60

Sequence

V

P

K

A

A

M

A

K

P

A

A

A

E

Q

A

T

G

Y

V

V

G

G

I

S

P

F

G

Q

R

K

R

L

R

T

V

V

D

V

S

A

L

S

W

D

R

V

L

R

C

R

Q

T

A

L

G

R

H

G

G

P

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

Disorder confidence

.

.

.

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.

.

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70

.

.

Sequence

A

G

P

D

H

L

D

Q

R

D

H

R

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 39%) Alpha helix ( 46%) Beta strand ( 6%)

Rank Aligned region

PDB 1dbx chain A Region: 1 - 66 Aligned: 62 Modelled: 66 Confidence: 99.6% Identity: 42% Fold: YbaK/ProRS associated domain Superfamily: YbaK/ProRS associated domain Family: YbaK/ProRS associated domain Phyre2 PDB 1wdv chain A Region: 2 - 66 Aligned: 63 Modelled: 63 Confidence: 99.6% Identity: 25% Fold: YbaK/ProRS associated domain Superfamily: YbaK/ProRS associated domain Family: YbaK/ProRS associated domain Phyre2 PDB 2dxa chain A Region: 1 - 66 Aligned: 64 Modelled: 66 Confidence: 99.5% Identity: 34% PDB header:translation Chain: A: PDB Molecule:protein ybak; PDBTitle: crystal structure of trans editing enzyme prox from e.coli Phyre2 PDB 2cx5 chain B Region: 2 - 66 Aligned: 63 Modelled: 63 Confidence: 99.5% Identity: 27% PDB header:translation Chain: B: PDB Molecule:a putative trans-editing enzyme; PDBTitle: crystal structure of a putative trans-editing enzyme for2 prolyl trna synthetase Phyre2 PDB 1vki chain A Region: 1 - 66 Aligned: 64 Modelled: 66 Confidence: 99.5% Identity: 17% Fold: YbaK/ProRS associated domain Superfamily: YbaK/ProRS associated domain Family: YbaK/ProRS associated domain Phyre2 PDB 1vjf chain A Region: 1 - 66 Aligned: 64 Modelled: 66 Confidence: 99.4% Identity: 19% Fold: YbaK/ProRS associated domain Superfamily: YbaK/ProRS associated domain Family: YbaK/ProRS associated domain Phyre2 PDB 3mem chain A Region: 2 - 70 Aligned: 67 Modelled: 69 Confidence: 99.4% Identity: 10% PDB header:signaling protein Chain: A: PDB Molecule:putative signal transduction protein; PDBTitle: crystal structure of a putative signal transduction protein2 (maqu_0641) from marinobacter aquaeolei vt8 at 2.25 a resolution Phyre2 PDB 3op6 chain B Region: 2 - 66 Aligned: 63 Modelled: 65 Confidence: 99.3% Identity: 17% PDB header:unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an oligo-nucleotide binding protein (lpg1207)2 from legionella pneumophila subsp. pneumophila str. philadelphia 1 at3 2.00 a resolution Phyre2 PDB 4d2i chain B Region: 2 - 56 Aligned: 52 Modelled: 55 Confidence: 50.0% Identity: 15% PDB header:hydrolase Chain: B: PDB Molecule:hera; PDBTitle: crystal structure of the hera hexameric dna translocase2 from sulfolobus solfataricus bound to amp-pnp Phyre2 PDB 3uep chain B Region: 12 - 61 Aligned: 46 Modelled: 50 Confidence: 8.6% Identity: 17% PDB header:protein transport Chain: B: PDB Molecule:yscq-c, type iii secretion protein; PDBTitle: crystal structure of yscq-c from yersinia pseudotuberculosis Phyre2 PDB 1xi8 chain A domain 3 Region: 36 - 63 Aligned: 28 Modelled: 28 Confidence: 8.6% Identity: 25% Fold: Molybdenum cofactor biosynthesis proteins Superfamily: Molybdenum cofactor biosynthesis proteins Family: MoeA central domain-like Phyre2 PDB 5jpq chain D Region: 26 - 41 Aligned: 16 Modelled: 16 Confidence: 8.3% Identity: 19% PDB header:ribosome Chain: D: PDB Molecule:wd40 domain proteins; PDBTitle: cryo-em structure of the 90s pre-ribosome Phyre2 PDB 3bqh chain A Region: 16 - 47 Aligned: 31 Modelled: 32 Confidence: 7.0% Identity: 32% PDB header:oxidoreductase Chain: A: PDB Molecule:peptide methionine sulfoxide reductase msra/msrb; PDBTitle: structure of the central domain (msra) of neisseria meningitidis pilb2 (oxidized form) Phyre2 PDB 2j89 chain A Region: 16 - 47 Aligned: 31 Modelled: 32 Confidence: 6.8% Identity: 26% PDB header:oxidoreductase Chain: A: PDB Molecule:methionine sulfoxide reductase a; PDBTitle: functional and structural aspects of poplar cytosolic and2 plastidial type a methionine sulfoxide reductases Phyre2 PDB 2nqr chain A domain 3 Region: 36 - 57 Aligned: 22 Modelled: 22 Confidence: 6.4% Identity: 14% Fold: Molybdenum cofactor biosynthesis proteins Superfamily: Molybdenum cofactor biosynthesis proteins Family: MoeA central domain-like Phyre2 PDB 2hbp chain A Region: 1 - 17 Aligned: 17 Modelled: 17 Confidence: 6.4% Identity: 29% PDB header:endocytosis, protein binding Chain: A: PDB Molecule:cytoskeleton assembly control protein sla1; PDBTitle: solution structure of sla1 homology domain 1 Phyre2 PDB 4mj7 chain B Region: 26 - 41 Aligned: 16 Modelled: 16 Confidence: 6.2% Identity: 25% PDB header:rna binding protein Chain: B: PDB Molecule:rrna-processing protein utp23; PDBTitle: crystal structure of the pin domain of saccharomyces cerevisiae utp23 Phyre2 PDB 1spi chain A Region: 48 - 70 Aligned: 22 Modelled: 23 Confidence: 6.1% Identity: 14% Fold: Carbohydrate phosphatase Superfamily: Carbohydrate phosphatase Family: Inositol monophosphatase/fructose-1,6-bisphosphatase-like Phyre2 PDB 5oez chain A Region: 48 - 70 Aligned: 22 Modelled: 23 Confidence: 5.7% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:fbp protein; PDBTitle: crystal structure of leishmania major fructose-1,6-bisphosphatase in2 apo form. Phyre2 PDB 1bk4 chain A Region: 48 - 70 Aligned: 22 Modelled: 23 Confidence: 5.5% Identity: 18% Fold: Carbohydrate phosphatase Superfamily: Carbohydrate phosphatase Family: Inositol monophosphatase/fructose-1,6-bisphosphatase-like Phyre2 1 d1dbxa_ 2 d1wdva_ 3 c2dxaA_ 4 c2cx5B_ 5 d1vkia_ 6 d1vjfa_ 7 c3memA_ 8 c3op6B_ 9 c4d2iB_ 10 c3uepB_ 11 d1xi8a3 12 c5jpqd_ 13 c3bqhA_ 14 c2j89A_ 15 d2nqra3 16 c2hbpA_ 17 c4mj7B_ 18 d1spia_ 19 c5oezA_ 20 d1bk4a_ 21 22