1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	G	P	L	L	P	P	T	V	P	G	W	R	S	R	A	E	R	F	D	M	A	V	L	E	A	Y	E	P	I	E	R	R	W	Q	E	R	V	S	Q	L	D	I	A	V	D	E	I	P	R	I	A	A	K	D	P	E	S	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?		?	?	?	?	?	?																																				?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Q	W	P	P	E	V	I	A	D	G	P	I	A	L	A	R	L	I	P	A	G	V	D	V	R	G	N	A	T	R	A	R	I	V	L	F	R	K	P	I	E	R	R	A	K	D	T	E	E	L	G	E	L	L	H	E	I	L	V	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?										?	?	?	?	?	?	?	?	?																		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.
Sequence		Q	V	A	I	Y	L	D	V	D	P	S	V	I	D	P	T	I	D	D
Secondary structure
SS confidence
Disorder															?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 36%) Alpha helix ( 43%) Beta strand ( 9%)

Rank Aligned region

PDB 3e11 chain A domain 1 Region: 15 - 136 Aligned: 108 Modelled: 122 Confidence: 100.0% Identity: 20% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: TTHA0227-like Phyre2 PDB 2ejq chain A domain 1 Region: 16 - 126 Aligned: 100 Modelled: 104 Confidence: 99.9% Identity: 12% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: TTHA0227-like Phyre2 PDB 2j83 chain B Region: 116 - 128 Aligned: 13 Modelled: 13 Confidence: 94.3% Identity: 8% PDB header:hydrolase Chain: B: PDB Molecule:ulilysin; PDBTitle: ulilysin metalloprotease in complex with batimastat. Phyre2 PDB 1k7i chain A domain 2 Region: 7 - 129 Aligned: 114 Modelled: 123 Confidence: 93.6% Identity: 11% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Serralysin-like metalloprotease, catalytic (N-terminal) domain Phyre2 PDB 3lmc chain A Region: 105 - 129 Aligned: 25 Modelled: 25 Confidence: 92.4% Identity: 8% PDB header:hydrolase Chain: A: PDB Molecule:peptidase, zinc-dependent; PDBTitle: crystal structure of zinc-dependent peptidase from methanocorpusculum2 labreanum (strain z), northeast structural genomics consortium target3 mur16 Phyre2 PDB 2xhq chain A Region: 105 - 129 Aligned: 25 Modelled: 25 Confidence: 92.2% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:archaemetzincin; PDBTitle: crystal structure of archaemetzincin (amza) from archaeoglobus2 fulgidus at 1.45 a resolution Phyre2 PDB 1y93 chain A domain 1 Region: 114 - 129 Aligned: 16 Modelled: 16 Confidence: 91.4% Identity: 19% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Matrix metalloproteases, catalytic domain Phyre2 PDB 2x7m chain A Region: 105 - 129 Aligned: 25 Modelled: 25 Confidence: 91.4% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:archaemetzincin; PDBTitle: crystal structure of archaemetzincin (amza) from methanopyrus2 kandleri at 1.5 a resolution Phyre2 PDB 1rm8 chain A Region: 114 - 129 Aligned: 16 Modelled: 16 Confidence: 91.3% Identity: 19% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Matrix metalloproteases, catalytic domain Phyre2 PDB 1qib chain A Region: 114 - 129 Aligned: 16 Modelled: 16 Confidence: 91.2% Identity: 6% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Matrix metalloproteases, catalytic domain Phyre2 PDB 1hv5 chain A Region: 114 - 129 Aligned: 16 Modelled: 16 Confidence: 91.2% Identity: 13% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Matrix metalloproteases, catalytic domain Phyre2 PDB 2ovx chain A domain 1 Region: 114 - 129 Aligned: 16 Modelled: 16 Confidence: 91.2% Identity: 25% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Matrix metalloproteases, catalytic domain Phyre2 PDB 1bqq chain M Region: 114 - 129 Aligned: 16 Modelled: 16 Confidence: 91.1% Identity: 13% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Matrix metalloproteases, catalytic domain Phyre2 PDB 2xs4 chain A Region: 114 - 129 Aligned: 16 Modelled: 16 Confidence: 91.0% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:karilysin protease; PDBTitle: structure of karilysin catalytic mmp domain in complex with magnesium Phyre2 PDB 1cgl chain A Region: 114 - 129 Aligned: 16 Modelled: 16 Confidence: 90.5% Identity: 19% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Matrix metalloproteases, catalytic domain Phyre2 PDB 1mmq chain A Region: 114 - 129 Aligned: 16 Modelled: 16 Confidence: 90.4% Identity: 6% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Matrix metalloproteases, catalytic domain Phyre2 PDB 1hov chain A Region: 114 - 129 Aligned: 16 Modelled: 16 Confidence: 90.3% Identity: 6% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Matrix metalloproteases, catalytic domain Phyre2 PDB 1eak chain A domain 2 Region: 114 - 129 Aligned: 16 Modelled: 16 Confidence: 90.2% Identity: 13% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Matrix metalloproteases, catalytic domain Phyre2 PDB 1q3a chain A Region: 114 - 129 Aligned: 16 Modelled: 16 Confidence: 89.9% Identity: 13% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Matrix metalloproteases, catalytic domain Phyre2 PDB 1hy7 chain A Region: 114 - 129 Aligned: 16 Modelled: 16 Confidence: 89.9% Identity: 13% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Matrix metalloproteases, catalytic domain Phyre2 1 d3e11a1 2 d2ejqa1 3 c2j83B_ 4 d1k7ia2 5 c3lmcA_ 6 c2xhqA_ 7 d1y93a1 8 c2x7mA_ 9 d1rm8a_ 10 d1qiba_ 11 d1hv5a_ 12 d2ovxa1 13 d1bqqm_ 14 c2xs4A_ 15 d1cgla_ 16 d1mmqa_ 17 d1hova_ 18 d1eaka2 19 d1q3aa_ 20 d1hy7a_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131