1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	R	L	V	L	G	S	A	S	P	G	R	L	K	V	L	R	D	A	G	I	E	P	L	V	I	A	S	H	V	D	E	D	V	V	I	A	A	L	G	P	D	A	V	P	S	D	V	V	C	V	L	A	A	A	K	A	A	Q
Secondary structure
SS confidence
Disorder		?	?	?				?																															?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	A	T	T	L	T	G	T	Q	R	I	V	A	A	D	C	V	V	V	A	C	D	S	M	L	Y	I	E	G	R	L	L	G	K	P	A	S	I	D	E	A	R	E	Q	W	R	S	M	A	G	R	A	G	Q	L	Y	T	G	H	G
Secondary structure
SS confidence
Disorder								?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	I	R	L	Q	D	N	K	T	V	Y	R	A	A	E	T	A	I	T	T	V	Y	F	G	T	P	S	A	S	D	L	E	A	Y	L	A	S	G	E	S	L	R	V	A	G	G	F	T	L	D	G	L	G	G	W	F	I	D	G	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.
Sequence		Q	G	N	P	S	N	V	I	G	L	S	L	P	L	L	R	S	L	V	Q	R	C	G	L	S	V	A	A	L	W	A	G	N	A	G	G	P	A	H	K	Q	Q
Secondary structure
SS confidence
Disorder																														?		?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 12%) Alpha helix ( 31%) Beta strand ( 30%)

Rank Aligned region

PDB 4oo0 chain B Region: 1 - 206 Aligned: 200 Modelled: 206 Confidence: 100.0% Identity: 25% PDB header:hydrolase Chain: B: PDB Molecule:maf-like protein bcal2394; PDBTitle: crystal structure of maf-like protein bcej2315_23540 from burkholderia2 cenocepacia Phyre2 PDB 4jhc chain A Region: 2 - 205 Aligned: 188 Modelled: 204 Confidence: 100.0% Identity: 28% PDB header:cell cycle Chain: A: PDB Molecule:maf-like protein ycef; PDBTitle: crystal structure of the uncharacterized maf protein ycef from e. coli Phyre2 PDB 2amh chain A domain 1 Region: 1 - 202 Aligned: 188 Modelled: 202 Confidence: 100.0% Identity: 18% Fold: Anticodon-binding domain-like Superfamily: ITPase-like Family: Maf-like Phyre2 PDB 1ex2 chain A Region: 1 - 202 Aligned: 184 Modelled: 202 Confidence: 100.0% Identity: 28% Fold: Anticodon-binding domain-like Superfamily: ITPase-like Family: Maf-like Phyre2 PDB 2p5x chain B Region: 2 - 204 Aligned: 195 Modelled: 203 Confidence: 100.0% Identity: 28% PDB header:cell cycle Chain: B: PDB Molecule:n-acetylserotonin o-methyltransferase-like protein; PDBTitle: crystal structure of maf domain of human n-acetylserotonin o-2 methyltransferase-like protein Phyre2 PDB 4p0e chain B Region: 4 - 204 Aligned: 184 Modelled: 201 Confidence: 100.0% Identity: 29% PDB header:unknown function Chain: B: PDB Molecule:maf-like protein yhde; PDBTitle: yhde e33a (p212121 space group) Phyre2 PDB 4heb chain A Region: 2 - 202 Aligned: 182 Modelled: 201 Confidence: 100.0% Identity: 26% PDB header:cell cycle Chain: A: PDB Molecule:septum formation protein maf; PDBTitle: the crystal structure of maf protein of bacillus subtilis Phyre2 PDB 2car chain A domain 1 Region: 1 - 141 Aligned: 120 Modelled: 132 Confidence: 95.1% Identity: 12% Fold: Anticodon-binding domain-like Superfamily: ITPase-like Family: ITPase (Ham1) Phyre2 PDB 1k7k chain A Region: 1 - 141 Aligned: 125 Modelled: 140 Confidence: 93.3% Identity: 14% Fold: Anticodon-binding domain-like Superfamily: ITPase-like Family: ITPase (Ham1) Phyre2 PDB 1v7r chain A Region: 1 - 141 Aligned: 115 Modelled: 141 Confidence: 92.6% Identity: 18% Fold: Anticodon-binding domain-like Superfamily: ITPase-like Family: ITPase (Ham1) Phyre2 PDB 3tqu chain D Region: 1 - 141 Aligned: 124 Modelled: 138 Confidence: 86.8% Identity: 17% PDB header:hydrolase Chain: D: PDB Molecule:non-canonical purine ntp pyrophosphatase; PDBTitle: structure of a ham1 protein from coxiella burnetii Phyre2 PDB 1vp2 chain A Region: 3 - 137 Aligned: 118 Modelled: 126 Confidence: 81.3% Identity: 17% Fold: Anticodon-binding domain-like Superfamily: ITPase-like Family: ITPase (Ham1) Phyre2 PDB 1b78 chain A Region: 3 - 141 Aligned: 115 Modelled: 130 Confidence: 74.9% Identity: 19% Fold: Anticodon-binding domain-like Superfamily: ITPase-like Family: ITPase (Ham1) Phyre2 PDB 4bnq chain A Region: 2 - 141 Aligned: 117 Modelled: 140 Confidence: 65.4% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:non-canonical purine ntp pyrophosphatase; PDBTitle: the structure of the staphylococcus aureus ham1 protein Phyre2 PDB 1x3l chain A Region: 4 - 118 Aligned: 99 Modelled: 100 Confidence: 54.1% Identity: 12% PDB header:transferase Chain: A: PDB Molecule:hypothetical protein ph0495; PDBTitle: crystal structure of the ph0495 protein from pyrococccus horikoshii2 ot3 Phyre2 PDB 1pda chain A domain 1 Region: 5 - 28 Aligned: 24 Modelled: 24 Confidence: 44.5% Identity: 17% Fold: Periplasmic binding protein-like II Superfamily: Periplasmic binding protein-like II Family: Phosphate binding protein-like Phyre2 PDB 2ypn chain A Region: 5 - 28 Aligned: 24 Modelled: 24 Confidence: 41.9% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:protein (hydroxymethylbilane synthase); PDBTitle: hydroxymethylbilane synthase Phyre2 PDB 4nml chain A Region: 148 - 216 Aligned: 69 Modelled: 69 Confidence: 41.4% Identity: 14% PDB header:isomerase Chain: A: PDB Molecule:ribulose 5-phosphate isomerase; PDBTitle: 2.60 angstrom resolution crystal structure of putative ribose 5-2 phosphate isomerase from toxoplasma gondii me49 in complex with dl-3 malic acid Phyre2 PDB 4mlq chain A Region: 5 - 28 Aligned: 24 Modelled: 24 Confidence: 40.6% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:porphobilinogen deaminase; PDBTitle: crystal structure of bacillus megaterium porphobilinogen deaminase Phyre2 PDB 3dv0 chain I Region: 193 - 221 Aligned: 29 Modelled: 29 Confidence: 39.5% Identity: 17% PDB header:oxidoreductase/transferase Chain: I: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase PDBTitle: snapshots of catalysis in the e1 subunit of the pyruvate2 dehydrogenase multi-enzyme complex Phyre2 1 c4oo0B_ 2 c4jhcA_ 3 d2amha1 4 d1ex2a_ 5 c2p5xB_ 6 c4p0eB_ 7 c4hebA_ 8 d2cara1 9 d1k7ka_ 10 d1v7ra_ 11 c3tquD_ 12 d1vp2a_ 13 d1b78a_ 14 c4bnqA_ 15 c1x3lA_ 16 d1pdaa1 17 c2ypnA_ 18 c4nmlA_ 19 c4mlqA_ 20 c3dv0I_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99