Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD3288c_(usfY)_3669583_3669996
DateThu Aug 8 16:20:49 BST 2019
Unique Job ID7fa89d68d32dec0d
SequenceMGQIPPQPVR ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:41.653 Y:28.041 Z:30.515
Model (left) based on template c4wgiA_
Top template information
PDB header:apoptosis/inhibitor
Chain: A: PDB Molecule:maltose-binding periplasmic protein,induced myeloid
PDBTitle: a single diastereomer of a macrolactam core binds specifically to2 myeloid cell leukemia 1 (mcl1)
Confidence and coverage
Confidence: 46.4% Coverage: 49%
67 residues ( 49% of your sequence) have been modelled with 46.4% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
Please note: You must be registered and logged in to use Phyrealarm.
3D viewing
Interactive 3D view in JSmol
For other options to view your downloaded structure offline see the FAQ

Sequence analysis 

Download FASTA version

Secondary structure and disorder prediction [Show] 

Domain analysis [Show] 

Detailed template information [Hide] 

 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c4wgiA_
46.4 19
PDB header:apoptosis/inhibitor
Chain: A: PDB Molecule:maltose-binding periplasmic protein,induced myeloid
PDBTitle: a single diastereomer of a macrolactam core binds specifically to2 myeloid cell leukemia 1 (mcl1)
2c5ua4A_
36.7 19
PDB header:apoptosis
Chain: A: PDB Molecule:5-hl;
PDBTitle: crystal structure of a179l:bid bh3 complex
3c5v2sA_
35.1 27
PDB header:viral protein
Chain: A: PDB Molecule:envelope glycoprotein b;
PDBTitle: crystal structure of glycoprotein b from herpes simplex virus type i
4c2lx0A_
30.7 25
PDB header:membrane protein
Chain: A: PDB Molecule:membrane fusion protein p14;
PDBTitle: arced helix (arch) nmr structure of the reovirus p14 fusion-associated2 small transmembrane (fast) protein transmembrane domain (tmd) in3 dodecyl phosphocholine (dpc) micelles
5c5ohdB_
30.1 30
PDB header:membrane protein
Chain: B: PDB Molecule:growth hormone receptor;
PDBTitle: putative inactive (dormant) dimeric state of ghr transmembrane domain
6d1q59a_
27.2 18
Fold:Toxins' membrane translocation domains
Superfamily:Bcl-2 inhibitors of programmed cell death
Family:Bcl-2 inhibitors of programmed cell death
7c2a3lA_
22.2 56
PDB header:hydrolase
Chain: A: PDB Molecule:amp deaminase;
PDBTitle: x-ray structure of adenosine 5'-monophosphate deaminase from2 arabidopsis thaliana in complex with coformycin 5'-phosphate
8d2a3la1
22.2 56
Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Adenosine/AMP deaminase
9c2mkvA_
21.2 27
PDB header:transport protein
Chain: A: PDB Molecule:sodium/potassium-transporting atpase subunit gamma;
PDBTitle: structure of the na,k-atpase regulatory protein fxyd2b in micelles
10c5wddA_
21.0 18
PDB header:apoptosis
Chain: A: PDB Molecule:bcl-2-related ovarian killer protein;
PDBTitle: crystal structure of chicken bok
11c5f5uE_
20.2 33
PDB header:splicing
Chain: E: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of the snu23-prp38-mfap1(217-258) complex of2 chaetomium thermophilum
12c2jp3A_
16.9 11
PDB header:transcription
Chain: A: PDB Molecule:fxyd domain-containing ion transport regulator 4;
PDBTitle: solution structure of the human fxyd4 (chif) protein in sds2 micelles
13c2jo1A_
15.8 14
PDB header:hydrolase regulator
Chain: A: PDB Molecule:phospholemman;
PDBTitle: structure of the na,k-atpase regulatory protein fxyd1 in2 micelles
14c2a5yA_
15.6 21
PDB header:apoptosis
Chain: A: PDB Molecule:apoptosis regulator ced-9;
PDBTitle: structure of a ced-4/ced-9 complex
15c4xz6A_
15.5 19
PDB header:transport protein
Chain: A: PDB Molecule:glycine betaine/proline abc transporter, periplasmic
PDBTitle: tmox in complex with tmao
16c6hwhX_
14.3 23
PDB header:electron transport
Chain: X: PDB Molecule:cytochrome c oxidase polypeptide 4;
PDBTitle: structure of a functional obligate respiratory supercomplex from2 mycobacterium smegmatis
17c6ijjF_
13.6 27
PDB header:membrane protein
Chain: F: PDB Molecule:psaf;
PDBTitle: photosystem i of chlamydomonas reinhardtii
18c1ciiA_
13.2 13
PDB header:transmembrane protein
Chain: A: PDB Molecule:colicin ia;
PDBTitle: colicin ia
19c3kj2B_
13.0 41
PDB header:apoptosis
Chain: B: PDB Molecule:bcl-2-like protein 11;
PDBTitle: mcl-1 in complex with bim bh3 mutant f4ae
20c2yv6A_
12.1 22
PDB header:apoptosis
Chain: A: PDB Molecule:bcl-2 homologous antagonist/killer;
PDBTitle: crystal structure of human bcl-2 family protein bak
21d1gzga_
not modelled 12.0 33
Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
22c3l6gA_
not modelled 11.8 11
PDB header:glycine betaine-binding protein
Chain: A: PDB Molecule:betaine abc transporter permease and substrate binding
PDBTitle: crystal structure of lactococcal opuac in its open conformation
23c5f5uB_
not modelled 11.6 41
PDB header:splicing
Chain: B: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of the snu23-prp38-mfap1(217-258) complex of2 chaetomium thermophilum
24c2xa0A_
not modelled 11.6 24
PDB header:apoptosis
Chain: A: PDB Molecule:apoptosis regulator bcl-2;
PDBTitle: crystal structure of bcl-2 in complex with a bax bh32 peptide
25c2ks1B_
not modelled 11.3 21
PDB header:transferase
Chain: B: PDB Molecule:epidermal growth factor receptor;
PDBTitle: heterodimeric association of transmembrane domains of erbb1 and erbb22 receptors enabling kinase activation
26c3kdpG_
not modelled 11.1 29
PDB header:hydrolase
Chain: G: PDB Molecule:na+/k+ atpase gamma subunit transcript variant a;
PDBTitle: crystal structure of the sodium-potassium pump
27c3kdpH_
not modelled 11.1 29
PDB header:hydrolase
Chain: H: PDB Molecule:na+/k+ atpase gamma subunit transcript variant a;
PDBTitle: crystal structure of the sodium-potassium pump
28c2rgwD_
not modelled 11.0 32
PDB header:transferase
Chain: D: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: catalytic subunit of m. jannaschii aspartate2 transcarbamoylase
29c2zxeG_
not modelled 10.9 26
PDB header:hydrolase/transport protein
Chain: G: PDB Molecule:phospholemman-like protein;
PDBTitle: crystal structure of the sodium - potassium pump in the e2.2k+.pi2 state
30c2o2fA_
not modelled 10.6 26
PDB header:apoptosis
Chain: A: PDB Molecule:apoptosis regulator bcl-2;
PDBTitle: solution structure of the anti-apoptotic protein bcl-2 in2 complex with an acyl-sulfonamide-based ligand
31d5easa1
not modelled 10.5 13
Fold:alpha/alpha toroid
Superfamily:Terpenoid cyclases/Protein prenyltransferases
Family:Terpenoid cyclase N-terminal domain
32c5ujqA_
not modelled 10.3 20
PDB header:antimicrobial protein
Chain: A: PDB Molecule:bacteriocin;
PDBTitle: nmr solution structure of the two-component bacteriocin cbnxy
33d2c1ha1
not modelled 10.2 37
Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
34d1pq1a_
not modelled 10.2 20
Fold:Toxins' membrane translocation domains
Superfamily:Bcl-2 inhibitors of programmed cell death
Family:Bcl-2 inhibitors of programmed cell death
35d1h7na_
not modelled 10.1 17
Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
36d1l6sa_
not modelled 10.0 37
Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
37c4hqjE_
not modelled 9.7 21
PDB header:hydrolase/transport protein
Chain: E: PDB Molecule:na+/k+ atpase gamma subunit transcript variant a;
PDBTitle: crystal structure of na+,k+-atpase in the na+-bound state
38c5f5uH_
not modelled 9.7 41
PDB header:splicing
Chain: H: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of the snu23-prp38-mfap1(217-258) complex of2 chaetomium thermophilum
39c4deyB_
not modelled 9.5 33
PDB header:transport protein
Chain: B: PDB Molecule:voltage-dependent l-type calcium channel subunit alpha-1c;
PDBTitle: crystal structure of the voltage dependent calcium channel beta-22 subunit in complex with the cav1.2 i-ii linker.
40c2ip6A_
not modelled 8.8 23
PDB header:antimicrobial protein
Chain: A: PDB Molecule:papb;
PDBTitle: crystal structure of pedb
41d1ysga1
not modelled 8.8 24
Fold:Toxins' membrane translocation domains
Superfamily:Bcl-2 inhibitors of programmed cell death
Family:Bcl-2 inhibitors of programmed cell death
42d2v0ea1
not modelled 8.8 30
Fold:GYF/BRK domain-like
Superfamily:BRK domain-like
Family:BRK domain-like
43c4hqjG_
not modelled 8.4 19
PDB header:hydrolase/transport protein
Chain: G: PDB Molecule:na+/k+ atpase gamma subunit transcript variant a;
PDBTitle: crystal structure of na+,k+-atpase in the na+-bound state
44c2ckaA_
not modelled 8.3 40
PDB header:hydrolase
Chain: A: PDB Molecule:chromodomain-helicase-dna-binding protein 8;
PDBTitle: solution structures of the brk domains of the human chromo2 helicase domain 7 and 8, reveals structural similarity3 with gyf domain suggesting a role in protein interaction
45d2ckaa1
not modelled 8.3 40
Fold:GYF/BRK domain-like
Superfamily:BRK domain-like
Family:BRK domain-like
46c6igzF_
not modelled 8.1 22
PDB header:plant protein
Chain: F: PDB Molecule:psaf;
PDBTitle: structure of psi-lhci
47c3d7vB_
not modelled 8.1 44
PDB header:apoptosis
Chain: B: PDB Molecule:bcl-2-like protein 11;
PDBTitle: crystal structure of mcl-1 in complex with an mcl-1 selective bh32 ligand
48c2jpkA_
not modelled 8.1 63
PDB header:antimicrobial protein
Chain: A: PDB Molecule:bacteriocin lactococcin-g subunit beta;
PDBTitle: lactococcin g-b in dpc
49c6f2dI_
not modelled 8.1 19
PDB header:protein transport
Chain: I: PDB Molecule:flagellar biosynthetic protein fliq;
PDBTitle: a flipqr complex forms the core of the salmonella type iii secretion2 system export apparatus.
50c6f2dJ_
not modelled 8.1 19
PDB header:protein transport
Chain: J: PDB Molecule:flagellar biosynthetic protein fliq;
PDBTitle: a flipqr complex forms the core of the salmonella type iii secretion2 system export apparatus.
51c5tn2B_
not modelled 8.1 50
PDB header:transcription
Chain: B: PDB Molecule:hth-type transcriptional regulator sinr;
PDBTitle: solution structure of the c-terminal multimerization domain of the2 master biofilm-regulator sinr from bacillus subtilis
52c2ckcA_
not modelled 8.0 30
PDB header:hydrolase
Chain: A: PDB Molecule:chromodomain-helicase-dna-binding protein 7;
PDBTitle: solution structures of the brk domains of the human chromo2 helicase domain 7 and 8, reveals structural similarity3 with gyf domain suggesting a role in protein interaction
53d2ckca1
not modelled 8.0 30
Fold:GYF/BRK domain-like
Superfamily:BRK domain-like
Family:BRK domain-like
54c4p5aB_
not modelled 8.0 25
PDB header:transferase
Chain: B: PDB Molecule:thymidylate synthase thyx;
PDBTitle: crystal structure of a ump/dump methylase polb from streptomyces2 cacaoi bound with 5-br ump
55d1kfia4
not modelled 8.0 83
Fold:TBP-like
Superfamily:Phosphoglucomutase, C-terminal domain
Family:Phosphoglucomutase, C-terminal domain
56d1ml4a1
not modelled 7.9 30
Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
57d3pmga4
not modelled 7.9 83
Fold:TBP-like
Superfamily:Phosphoglucomutase, C-terminal domain
Family:Phosphoglucomutase, C-terminal domain
58c4ymkA_
not modelled 7.8 18
PDB header:oxidoreductase
Chain: A: PDB Molecule:acyl-coa desaturase 1;
PDBTitle: crystal structure of stearoyl-coenzyme a desaturase 1
59d2dl6a1
not modelled 7.7 40
Fold:GYF/BRK domain-like
Superfamily:BRK domain-like
Family:BRK domain-like
60c4zyoA_
not modelled 7.7 16
PDB header:oxidoreductase
Chain: A: PDB Molecule:acyl-coa desaturase;
PDBTitle: crystal structure of human integral membrane stearoyl-coa desaturase2 with substrate
61d1pv8a_
not modelled 7.7 17
Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
62c3io8D_
not modelled 7.5 67
PDB header:apoptosis
Chain: D: PDB Molecule:bcl-2-like protein 11;
PDBTitle: biml12f in complex with bcl-xl
63c4atyA_
not modelled 7.4 67
PDB header:oxidoreductase
Chain: A: PDB Molecule:terephthalate 1,2-cis-dihydrodiol dehydrogenase;
PDBTitle: crystal structure of a terephthalate 1,2-cis-2 dihydrodioldehydrogenase from burkholderia xenovorans3 lb400
64c6r6bI_
not modelled 7.3 16
PDB header:protein transport
Chain: I: PDB Molecule:surface presentation of antigens protein spaq;
PDBTitle: structure of the core shigella flexneri type iii secretion system2 export gate complex sctrst (spa24/spa9/spa29).
65c5t3pB_
not modelled 7.0 24
PDB header:hydrolase
Chain: B: PDB Molecule:peroxisomal coenzyme a diphosphatase nudt7;
PDBTitle: crystal structure of human peroxisomal coenzyme a diphosphatase nudt7
66c3n23E_
not modelled 7.0 18
PDB header:hydrolase
Chain: E: PDB Molecule:na+/k+ atpase gamma subunit transcript variant a;
PDBTitle: crystal structure of the high affinity complex between ouabain and the2 e2p form of the sodium-potassium pump
67c1ml4A_
not modelled 7.0 30
PDB header:transferase
Chain: A: PDB Molecule:aspartate transcarbamoylase;
PDBTitle: the pala-liganded aspartate transcarbamoylase catalytic subunit from2 pyrococcus abyssi
68c2voyB_
not modelled 6.9 29
PDB header:hydrolase
Chain: B: PDB Molecule:sarcoplasmic/endoplasmic reticulum calcium atpase 1;
PDBTitle: cryoem model of copa, the copper transporting atpase from2 archaeoglobus fulgidus
69c4jo8B_
not modelled 6.9 36
PDB header:immune system/viral protein
Chain: B: PDB Molecule:killer cell lectin-like receptor 8;
PDBTitle: crystal structure of the activating ly49h receptor in complex with2 m157 (g1f strain)
70c6akfC_
not modelled 6.9 27
PDB header:membrane protein/toxin
Chain: C: PDB Molecule:claudin-3;
PDBTitle: crystal structure of mouse claudin-3 p134a mutant in complex with c-2 terminal fragment of clostridium perfringens enterotoxin
71c5ir6B_
not modelled 6.8 4
PDB header:oxidoreductase
Chain: B: PDB Molecule:bd-type quinol oxidase subunit ii;
PDBTitle: the structure of bd oxidase from geobacillus thermodenitrificans
72c3io8B_
not modelled 6.7 35
PDB header:apoptosis
Chain: B: PDB Molecule:bcl-2-like protein 11;
PDBTitle: biml12f in complex with bcl-xl
73c4zr0A_
not modelled 6.6 19
PDB header:oxidoreductase
Chain: A: PDB Molecule:ceramide very long chain fatty acid hydroxylase scs7;
PDBTitle: full length scs7p (only hydroxylase domain visible)
74c5f5tD_
not modelled 6.5 33
PDB header:splicing
Chain: D: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of the prp38-mfap1 complex of chaetomium2 thermophilum
75c1p58E_
not modelled 6.4 25
PDB header:virus
Chain: E: PDB Molecule:envelope protein m;
PDBTitle: complex organization of dengue virus membrane proteins as revealed by2 9.5 angstrom cryo-em reconstruction
76c4k7eA_
not modelled 6.3 24
PDB header:viral protein
Chain: A: PDB Molecule:nucleoprotein;
PDBTitle: crystal structure of junin virus nucleoprotein
77c3ah5E_
not modelled 6.2 17
PDB header:transferase
Chain: E: PDB Molecule:thymidylate synthase thyx;
PDBTitle: crystal structure of flavin dependent thymidylate synthase thyx from2 helicobacter pylori complexed with fad and dump
78c5zzjC_
not modelled 6.1 43
PDB header:lyase
Chain: C: PDB Molecule:santalene synthase;
PDBTitle: crystal structure of a enzyme from santalum album
79c5wosB_
not modelled 6.1 67
PDB header:viral protein
Chain: B: PDB Molecule:bcl-2-like protein 11;
PDBTitle: structural and functional insights into canarypox virus cnp0582 regulation of apoptosis
80c2v6qB_
not modelled 6.0 67
PDB header:apoptosis
Chain: B: PDB Molecule:bcl-2-like protein 11;
PDBTitle: crystal structure of a bhrf-1 : bim bh3 complex
81c1vytE_
not modelled 5.9 33
PDB header:transport protein
Chain: E: PDB Molecule:voltage-dependent l-type calcium channel
PDBTitle: beta3 subunit complexed with aid
82c2wh6B_
not modelled 5.9 67
PDB header:apoptosis
Chain: B: PDB Molecule:bcl-2-like protein 11;
PDBTitle: crystal structure of anti-apoptotic bhrf1 in complex with the bim bh32 domain
83c4d2mD_
not modelled 5.9 67
PDB header:apoptosis
Chain: D: PDB Molecule:bcl-2-like protein 11;
PDBTitle: vaccinia virus f1l bound to bim bh3
84d1h21a_
not modelled 5.8 18
Fold:Multiheme cytochromes
Superfamily:Multiheme cytochromes
Family:Di-heme elbow motif
85d1vlva1
not modelled 5.7 27
Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
86c5ilqA_
not modelled 5.5 19
PDB header:transferase
Chain: A: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: crystal structure of truncated unliganded aspartate transcarbamoylase2 from plasmodium falciparum
87c3b9bA_
not modelled 5.5 15
PDB header:hydrolase
Chain: A: PDB Molecule:sarcoplasmic/endoplasmic reticulum calcium
PDBTitle: structure of the e2 beryllium fluoride complex of the serca2 ca2+-atpase
88d1y5ic1
not modelled 5.4 23
Fold:Heme-binding four-helical bundle
Superfamily:Respiratory nitrate reductase 1 gamma chain
Family:Respiratory nitrate reductase 1 gamma chain
89c6nhwB_
not modelled 5.4 21
PDB header:immune system
Chain: B: PDB Molecule:tumor necrosis factor receptor superfamily member 10b;
PDBTitle: structure of the transmembrane domain of the death receptor 5 - dimer2 of trimer
90c6nhwF_
not modelled 5.4 21
PDB header:immune system
Chain: F: PDB Molecule:tumor necrosis factor receptor superfamily member 10b;
PDBTitle: structure of the transmembrane domain of the death receptor 5 - dimer2 of trimer
91c6nhwC_
not modelled 5.4 21
PDB header:immune system
Chain: C: PDB Molecule:tumor necrosis factor receptor superfamily member 10b;
PDBTitle: structure of the transmembrane domain of the death receptor 5 - dimer2 of trimer
92c6nhwE_
not modelled 5.4 21
PDB header:immune system
Chain: E: PDB Molecule:tumor necrosis factor receptor superfamily member 10b;
PDBTitle: structure of the transmembrane domain of the death receptor 5 - dimer2 of trimer
93c6nhwA_
not modelled 5.4 21
PDB header:immune system
Chain: A: PDB Molecule:tumor necrosis factor receptor superfamily member 10b;
PDBTitle: structure of the transmembrane domain of the death receptor 5 - dimer2 of trimer
94c6nhwD_
not modelled 5.4 21
PDB header:immune system
Chain: D: PDB Molecule:tumor necrosis factor receptor superfamily member 10b;
PDBTitle: structure of the transmembrane domain of the death receptor 5 - dimer2 of trimer
95c2hi1A_
not modelled 5.3 80
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:4-hydroxythreonine-4-phosphate dehydrogenase 2;
PDBTitle: the structure of a putative 4-hydroxythreonine-4-phosphate2 dehydrogenase from salmonella typhimurium.
96d2v0fa1
not modelled 5.3 50
Fold:GYF/BRK domain-like
Superfamily:BRK domain-like
Family:BRK domain-like
97d1e43a1
not modelled 5.3 36
Fold:Glycosyl hydrolase domain
Superfamily:Glycosyl hydrolase domain
Family:alpha-Amylases, C-terminal beta-sheet domain
98c2d35A_
not modelled 5.2 37
PDB header:cell cycle
Chain: A: PDB Molecule:cell division activator ceda;
PDBTitle: solution structure of cell division reactivation factor,2 ceda
99d1jb0f_
not modelled 5.1 31
Fold:Single transmembrane helix
Superfamily:Subunit III of photosystem I reaction centre, PsaF
Family:Subunit III of photosystem I reaction centre, PsaF

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below