1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	T	V	Y	H	Q	R	L	T	E	L	A	G	R	L	G	E	M	C	S	L	A	G	I	A	M	K	R	A	T	Q	A	L	L	E	A	D	I	G	A	A	E	Q	V	I	R	D	H	E	R	I	V	A	M	R	A	Q	V	E
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		K	E	A	F	A	L	L	A	L	Q	H	P	V	A	G	E	L	R	E	I	F	S	A	V	Q	I	I	A	D	T	E	R	M	G	A	L	A	V	H	I	A	K	I	T	R	R	E	Y	P	N	Q	V	L	P	E	E	V	R	N	C
Secondary structure
SS confidence
Disorder										?	?	?	?																																					?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		F	A	D	M	A	K	V	A	I	A	L	G	D	S	A	R	Q	V	L	V	N	R	D	P	Q	E	A	A	Q	L	H	D	R	D	D	A	M	D	D	L	H	R	H	L	L	S	V	L	I	D	R	E	W	R	H	G	V	R	V	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.
Sequence		V	E	T	A	L	L	G	R	F	F	E	R	F	A	D	H	A	V	E	V	G	R	R	V	I	F	M	V	T	G	V	L	P	T	E	D	E	I	S	T	Y
Secondary structure
SS confidence
Disorder																																		?	?				?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 7%) Alpha helix ( 86%) Beta strand ( 0%)

Rank Aligned region

PDB 1sum chain B Region: 2 - 212 Aligned: 209 Modelled: 211 Confidence: 100.0% Identity: 17% Fold: Spectrin repeat-like Superfamily: PhoU-like Family: PhoU-like Phyre2 PDB 1t72 chain A Region: 2 - 211 Aligned: 208 Modelled: 209 Confidence: 100.0% Identity: 24% Fold: Spectrin repeat-like Superfamily: PhoU-like Family: PhoU-like Phyre2 PDB 1xwm chain A Region: 5 - 212 Aligned: 206 Modelled: 208 Confidence: 100.0% Identity: 29% Fold: Spectrin repeat-like Superfamily: PhoU-like Family: PhoU-like Phyre2 PDB 4q25 chain B Region: 5 - 210 Aligned: 205 Modelled: 206 Confidence: 100.0% Identity: 23% PDB header:unknown function Chain: B: PDB Molecule:phosphate-specific transport system accessory protein phou PDBTitle: crystal structure of phou from pseudomonas aeruginosa Phyre2 PDB 2i0m chain A Region: 5 - 214 Aligned: 204 Modelled: 210 Confidence: 100.0% Identity: 23% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:phosphate transport system protein phou; PDBTitle: crystal structure of the phosphate transport system regulatory protein2 phou from streptococcus pneumoniae Phyre2 PDB 3l39 chain A Region: 12 - 208 Aligned: 188 Modelled: 197 Confidence: 99.8% Identity: 9% PDB header:phosphate-binding protein Chain: A: PDB Molecule:putative phou-like phosphate regulatory protein; PDBTitle: crystal structure of putative phou-like phosphate regulatory protein2 (bt4638) from bacteroides thetaiotaomicron vpi-5482 at 1.93 a3 resolution Phyre2 PDB 2olt chain B Region: 11 - 204 Aligned: 185 Modelled: 194 Confidence: 99.8% Identity: 15% PDB header:unknown function Chain: B: PDB Molecule:hypothetical protein; PDBTitle: crystal structure of a phou-like protein (so_3770) from shewanella2 oneidensis mr-1 at 2.00 a resolution Phyre2 PDB 1vct chain A domain 1 Region: 12 - 109 Aligned: 94 Modelled: 98 Confidence: 99.6% Identity: 22% Fold: Spectrin repeat-like Superfamily: PhoU-like Family: PhoU-like Phyre2 PDB 2bkn chain A Region: 12 - 112 Aligned: 97 Modelled: 101 Confidence: 99.3% Identity: 22% PDB header:membrane protein Chain: A: PDB Molecule:hypothetical protein ph0236; PDBTitle: structure analysis of unknown function protein Phyre2 PDB 5vwv chain B Region: 84 - 95 Aligned: 12 Modelled: 12 Confidence: 38.1% Identity: 25% PDB header:apoptosis Chain: B: PDB Molecule:bcl-2-like protein 11; PDBTitle: bak core latch dimer in complex with bim-bh3 - cubic Phyre2 PDB 5vww chain C Region: 84 - 95 Aligned: 12 Modelled: 12 Confidence: 37.6% Identity: 25% PDB header:apoptosis Chain: C: PDB Molecule:bcl-2-like protein 11; PDBTitle: bak core latch dimer in complex with bim-rt - tetragonal Phyre2 PDB 5vww chain D Region: 84 - 95 Aligned: 12 Modelled: 12 Confidence: 34.5% Identity: 25% PDB header:apoptosis Chain: D: PDB Molecule:bcl-2-like protein 11; PDBTitle: bak core latch dimer in complex with bim-rt - tetragonal Phyre2 PDB 1pq1 chain B Region: 84 - 95 Aligned: 12 Modelled: 12 Confidence: 29.3% Identity: 25% PDB header:apoptosis Chain: B: PDB Molecule:bcl2-like protein 11; PDBTitle: crystal structure of bcl-xl/bim Phyre2 PDB 3izc chain W Region: 57 - 100 Aligned: 44 Modelled: 44 Confidence: 28.2% Identity: 16% PDB header:ribosome Chain: W: PDB Molecule:60s ribosomal protein rpl22 (l22e); PDBTitle: localization of the large subunit ribosomal proteins into a 6.1 a2 cryo-em map of saccharomyces cerevisiae translating 80s ribosome Phyre2 PDB 5ua4 chain B Region: 185 - 196 Aligned: 12 Modelled: 12 Confidence: 27.4% Identity: 25% PDB header:apoptosis Chain: B: PDB Molecule:bh3-interacting domain death agonist; PDBTitle: crystal structure of a179l:bid bh3 complex Phyre2 PDB 5vmo chain B Region: 84 - 95 Aligned: 12 Modelled: 12 Confidence: 22.5% Identity: 17% PDB header:viral protein/apoptosis Chain: B: PDB Molecule:bcl-2 interacting mediator of cell death; PDBTitle: crystal structure of grouper iridovirus giv66:bim complex Phyre2 PDB 1l0o chain C Region: 198 - 221 Aligned: 24 Modelled: 24 Confidence: 20.9% Identity: 21% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Sigma3 and sigma4 domains of RNA polymerase sigma factors Family: Sigma4 domain Phyre2 PDB 1l0o chain C Region: 198 - 221 Aligned: 24 Modelled: 24 Confidence: 20.9% Identity: 21% PDB header:protein binding Chain: C: PDB Molecule:sigma factor; PDBTitle: crystal structure of the bacillus stearothermophilus anti-2 sigma factor spoiiab with the sporulation sigma factor3 sigmaf Phyre2 PDB 2k7w chain B Region: 86 - 95 Aligned: 10 Modelled: 10 Confidence: 20.3% Identity: 30% PDB header:apoptosis Chain: B: PDB Molecule:bcl-2-like protein 11; PDBTitle: bax activation is initiated at a novel interaction site Phyre2 PDB 4qvf chain B Region: 84 - 95 Aligned: 12 Modelled: 12 Confidence: 18.6% Identity: 25% PDB header:apoptosis Chain: B: PDB Molecule:peptide from bcl-2-like protein 11; PDBTitle: crystal structure of bcl-xl in complex with bim bh3 domain Phyre2 1 d1sumb_ 2 d1t72a_ 3 d1xwma_ 4 c4q25B_ 5 c2i0mA_ 6 c3l39A_ 7 c2oltB_ 8 d1vcta1 9 c2bknA_ 10 c5vwvB_ 11 c5vwwC_ 12 c5vwwD_ 13 c1pq1B_ 14 c3izcw_ 15 c5ua4B_ 16 c5vmoB_ 17 d1l0oc_ 18 c1l0oC_ 19 c2k7wB_ 20 c4qvfB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82