1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	P	A	A	S	A	S	D	R	V	E	E	L	V	R	R	R	G	G	E	L	V	E	L	S	H	A	I	H	A	E	P	E	L	A	F	A	E	H	R	S	C	A	K	A	Q	A	L	V	A	E	R	G	F	E	I	T	T	A	A
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	G	L	D	T	A	F	R	A	D	Y	G	S	G	P	L	V	V	G	V	C	A	E	Y	D	A	L	P	G	I	G	H	A	C	G	H	N	I	I	A	A	S	A	V	G	T	A	L	A	L	A	E	V	A	D	D	L	G	L	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	A	L	L	G	T	P	A	E	E	S	G	G	G	K	A	L	M	L	Q	A	G	T	F	D	D	V	A	V	A	V	M	V	H	P	G	P	T	D	I	A	G	A	R	S	L	A	L	S	E	V	T	V	R	Y	R	G	K	E	S
Secondary structure
SS confidence
Disorder																																									?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		H	A	A	V	A	P	H	L	G	V	N	A	A	D	A	V	T	V	A	Q	V	A	I	G	V	L	R	Q	Q	L	A	P	G	Q	M	V	H	G	I	V	T	D	G	G	Q	A	V	N	V	I	P	G	Q	A	R	L	Q	Y	A	M
Secondary structure
SS confidence
Disorder																										?	?	?	?						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		R	A	V	E	S	D	S	L	R	E	L	Q	T	R	M	F	A	C	F	A	A	G	A	L	A	A	G	C	E	Y	E	I	D	E	A	A	P	A	Y	A	E	L	K	P	D	P	W	L	A	D	V	C	R	E	E	M	Q	R	L	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		R	E	P	L	L	P	A	L	E	A	E	L	P	L	G	S	T	D	M	G	N	V	T	Q	V	L	P	G	I	H	P	V	I	G	L	D	A	G	A	A	T	V	H	Q	R	A	F	T	V	A	S	A	G	A	S	A	D	R	A	V
Secondary structure
SS confidence
Disorder							?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.
Sequence		V	D	G	A	I	M	L	A	R	T	V	V	R	L	A	Q	T	P	D	E	R	D	R	V	L	A	A	Q	Q	R	R	A	A	R
Secondary structure
SS confidence
Disorder																																?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 5%) Alpha helix ( 43%) Beta strand ( 20%) TM helix ( 4%) (View membrane topology prediction)

Rank Aligned region

PDB 3ram chain C Region: 6 - 391 Aligned: 382 Modelled: 386 Confidence: 100.0% Identity: 33% PDB header:hydrolase Chain: C: PDB Molecule:hmra protein; PDBTitle: crystal structure of hmra Phyre2 PDB 4ewt chain C Region: 6 - 376 Aligned: 361 Modelled: 370 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: C: PDB Molecule:peptidase, m20/m25/m40 family; PDBTitle: the crystal structure of a putative aminohydrolase from methicillin2 resistant staphylococcus aureus Phyre2 PDB 3io1 chain B Region: 9 - 377 Aligned: 348 Modelled: 349 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: B: PDB Molecule:aminobenzoyl-glutamate utilization protein; PDBTitle: crystal structure of aminobenzoyl-glutamate utilization2 protein from klebsiella pneumoniae Phyre2 PDB 1ysj chain B Region: 15 - 377 Aligned: 339 Modelled: 358 Confidence: 100.0% Identity: 24% PDB header:hydrolase Chain: B: PDB Molecule:protein yxep; PDBTitle: crystal structure of bacillus subtilis yxep protein (apc1829), a2 dinuclear metal binding peptidase from m20 family Phyre2 PDB 3pfo chain B Region: 2 - 375 Aligned: 356 Modelled: 373 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: B: PDB Molecule:putative acetylornithine deacetylase; PDBTitle: crystal structure of a putative acetylornithine deacetylase (rpa2325)2 from rhodopseudomonas palustris cga009 at 1.90 a resolution Phyre2 PDB 2q43 chain A Region: 11 - 379 Aligned: 350 Modelled: 368 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:iaa-amino acid hydrolase ilr1-like 2; PDBTitle: ensemble refinement of the protein crystal structure of iaa-aminoacid2 hydrolase from arabidopsis thaliana gene at5g56660 Phyre2 PDB 5k8n chain E Region: 7 - 377 Aligned: 356 Modelled: 371 Confidence: 100.0% Identity: 14% PDB header:hydrolase Chain: E: PDB Molecule:5-nitroanthranilic acid aminohydrolase; PDBTitle: 5naa-bound 5-nitroanthranilate aminohydrolase Phyre2 PDB 3dlj chain B Region: 6 - 376 Aligned: 360 Modelled: 371 Confidence: 100.0% Identity: 14% PDB header:hydrolase Chain: B: PDB Molecule:beta-ala-his dipeptidase; PDBTitle: crystal structure of human carnosine dipeptidase 1 Phyre2 PDB 2zog chain A Region: 5 - 376 Aligned: 362 Modelled: 369 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:cytosolic non-specific dipeptidase; PDBTitle: crystal structure of mouse carnosinase cn2 complexed with zn and2 bestatin Phyre2 PDB 1cg2 chain D Region: 8 - 377 Aligned: 356 Modelled: 369 Confidence: 100.0% Identity: 19% PDB header:metallocarboxypeptidase Chain: D: PDB Molecule:carboxypeptidase g2; PDBTitle: carboxypeptidase g2 Phyre2 PDB 5i4m chain B Region: 17 - 378 Aligned: 347 Modelled: 362 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: B: PDB Molecule:amidase, hydantoinase/carbamoylase family; PDBTitle: crystal structure of amidase, hydantoinase/carbamoylase family from2 burkholderia vietnamiensis Phyre2 PDB 5tp4 chain B Region: 8 - 376 Aligned: 346 Modelled: 350 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: B: PDB Molecule:amidase, hydantoinase/carbamoylase family; PDBTitle: crystal structure of a hydantoinase/carbamoylase family amidase from2 burkholderia ambifaria Phyre2 PDB 6c0d chain A Region: 17 - 375 Aligned: 336 Modelled: 350 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:amidase, hydantoinase/carbamoylase family; PDBTitle: crystal structure of an amidase (hydantoinase/carbamoylase family)2 from burkholderia phymatum Phyre2 PDB 3gb0 chain A Region: 17 - 376 Aligned: 343 Modelled: 359 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:peptidase t; PDBTitle: crystal structure of aminopeptidase pept (np_980509.1) from bacillus2 cereus atcc 10987 at 2.04 a resolution Phyre2 PDB 4g1p chain A Region: 1 - 378 Aligned: 366 Modelled: 377 Confidence: 100.0% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:cys-gly metallodipeptidase dug1; PDBTitle: structural and mechanistic basis of substrate recognition by novel di-2 peptidase dug1p from saccharomyces cerevisiae Phyre2 PDB 2v8g chain D Region: 7 - 384 Aligned: 362 Modelled: 377 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: D: PDB Molecule:beta-alanine synthase; PDBTitle: crystal structure of beta-alanine synthase from2 saccharomyces kluyveri in complex with the product beta-3 alanine Phyre2 PDB 3n5f chain B Region: 17 - 377 Aligned: 346 Modelled: 361 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: B: PDB Molecule:n-carbamoyl-l-amino acid hydrolase; PDBTitle: crystal structure of l-n-carbamoylase from geobacillus2 stearothermophilus cect43 Phyre2 PDB 4wjb chain B Region: 18 - 377 Aligned: 343 Modelled: 359 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: B: PDB Molecule:putative amidohydrolase/peptidase; PDBTitle: x-ray crystal structure of a putative amidohydrolase/peptidase from2 burkholderia cenocepacia Phyre2 PDB 1vgy chain B Region: 19 - 375 Aligned: 339 Modelled: 357 Confidence: 100.0% Identity: 21% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:succinyl-diaminopimelate desuccinylase; PDBTitle: crystal structure of succinyl diaminopimelate desuccinylase Phyre2 PDB 4pxe chain B Region: 17 - 377 Aligned: 347 Modelled: 358 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: B: PDB Molecule:ureidoglycolate hydrolase; PDBTitle: the crystal structure of atuah in complex with glyoxylate Phyre2 1 c3ramC_ 2 c4ewtC_ 3 c3io1B_ 4 c1ysjB_ 5 c3pfoB_ 6 c2q43A_ 7 c5k8nE_ 8 c3dljB_ 9 c2zogA_ 10 c1cg2D_ 11 c5i4mB_ 12 c5tp4B_ 13 c6c0dA_ 14 c3gb0A_ 15 c4g1pA_ 16 c2v8gD_ 17 c3n5fB_ 18 c4wjbB_ 19 c1vgyB_ 20 c4pxeB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151