1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	I	T	V	N	V	L	Y	F	G	A	V	R	E	A	C	K	V	A	H	E	K	I	S	L	E	S	G	T	T	V	D	G	L	V	D	Q	L	Q	I	D	Y	P	P	L	A	D	F	R	K	R	V	R	M	A	V	N	E	S	I
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	P	A	S	T	I	L	D	D	G	D	T	V	A	F	I	P	Q	V	A	G	G	S	D	V	Y	C	R	L	T	D	E	P	L	S	V	D	E	V	L	N	A	I	S	G	P	S	Q	G	G	A	V	I	F	V	G	T	V	R	N
Secondary structure
SS confidence
Disorder				?																			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		N	N	N	G	H	E	V	T	K	L	Y	Y	E	A	Y	P	A	M	V	H	R	T	L	M	D	I	I	E	E	C	E	R	Q	A	D	G	V	R	V	A	V	A	H	R	T	G	E	L	R	I	G	D	A	A	V	V	I	G	A	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.
Sequence		A	P	H	R	A	A	A	F	D	A	A	R	M	C	I	E	R	L	K	Q	D	V	P	I	W	K	K	E	F	A	L	D	G	V	E	W	V	A	N	R	P
Secondary structure
SS confidence
Disorder																																	?	?	?		?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 6%) Alpha helix ( 29%) Beta strand ( 38%)

Rank Aligned region

PDB 2qie chain A Region: 84 - 219 Aligned: 136 Modelled: 136 Confidence: 100.0% Identity: 36% PDB header:transferase Chain: A: PDB Molecule:molybdopterin-converting factor subunit 2; PDBTitle: staphylococcus aureus molybdopterin synthase in complex with precursor2 z Phyre2 PDB 6jbz chain C Region: 83 - 219 Aligned: 137 Modelled: 137 Confidence: 100.0% Identity: 35% PDB header:transferase Chain: C: PDB Molecule:molybdenum cofactor biosynthesis protein e; PDBTitle: structural analysis of molybdopterin synthases from two mycobacteria2 pathogens Phyre2 PDB 2omd chain B Region: 72 - 220 Aligned: 141 Modelled: 149 Confidence: 100.0% Identity: 35% PDB header:lyase Chain: B: PDB Molecule:molybdopterin-converting factor subunit 2; PDBTitle: crystal structure of molybdopterin converting factor subunit 22 (aq_2181) from aquifex aeolicus vf5 Phyre2 PDB 6jc0 chain D Region: 83 - 219 Aligned: 136 Modelled: 137 Confidence: 100.0% Identity: 38% PDB header:transferase Chain: D: PDB Molecule:putative molybdenum cofactor biosynthesis protein; PDBTitle: structural analysis of molybdopterin synthases from two mycobacteria2 pathogens Phyre2 PDB 1fm0 chain E Region: 83 - 221 Aligned: 132 Modelled: 139 Confidence: 100.0% Identity: 35% Fold: alpha/beta-Hammerhead Superfamily: Molybdopterin synthase subunit MoaE Family: Molybdopterin synthase subunit MoaE Phyre2 PDB 4ap8 chain A Region: 83 - 211 Aligned: 129 Modelled: 129 Confidence: 100.0% Identity: 39% PDB header:transferase Chain: A: PDB Molecule:molybdopterin synthase catalytic subunit; PDBTitle: crystal structure of human molybdopterin synthase catalytic subunit2 (mocs2b) Phyre2 PDB 3rpf chain B Region: 87 - 220 Aligned: 129 Modelled: 131 Confidence: 100.0% Identity: 23% PDB header:transferase Chain: B: PDB Molecule:molybdopterin synthase catalytic subunit; PDBTitle: protein-protein complex of subunit 1 and 2 of molybdopterin-converting2 factor from helicobacter pylori 26695 Phyre2 PDB 2wp4 chain A Region: 85 - 211 Aligned: 120 Modelled: 127 Confidence: 100.0% Identity: 80% PDB header:transferase Chain: A: PDB Molecule:molybdopterin-converting factor subunit 2 1; PDBTitle: crystal structure of rv3119 from mycobacterium tuberculosis Phyre2 PDB 1nvj chain A Region: 83 - 207 Aligned: 117 Modelled: 125 Confidence: 100.0% Identity: 38% Fold: alpha/beta-Hammerhead Superfamily: Molybdopterin synthase subunit MoaE Family: Molybdopterin synthase subunit MoaE Phyre2 PDB 1v8c chain A Region: 5 - 150 Aligned: 143 Modelled: 146 Confidence: 100.0% Identity: 22% PDB header:protein binding Chain: A: PDB Molecule:moad related protein; PDBTitle: crystal structure of moad related protein from thermus2 thermophilus hb8 Phyre2 PDB 6jbz chain D Region: 2 - 82 Aligned: 81 Modelled: 81 Confidence: 99.9% Identity: 36% PDB header:transferase Chain: D: PDB Molecule:moad/this family protein; PDBTitle: structural analysis of molybdopterin synthases from two mycobacteria2 pathogens Phyre2 PDB 6jc0 chain A Region: 2 - 82 Aligned: 81 Modelled: 81 Confidence: 99.9% Identity: 32% PDB header:transferase Chain: A: PDB Molecule:putative molybdenum cofactor biosynthesis protein d2 PDBTitle: structural analysis of molybdopterin synthases from two mycobacteria2 pathogens Phyre2 PDB 5mpo chain A Region: 2 - 81 Aligned: 79 Modelled: 79 Confidence: 99.8% Identity: 32% PDB header:transferase Chain: A: PDB Molecule:molybdopterin synthase sulfur carrier subunit; PDBTitle: crystal structure of human molybdopterin synthase complex Phyre2 PDB 3po0 chain A Region: 3 - 82 Aligned: 80 Modelled: 80 Confidence: 99.8% Identity: 21% PDB header:protein binding Chain: A: PDB Molecule:small archaeal modifier protein 1; PDBTitle: crystal structure of samp1 from haloferax volcanii Phyre2 PDB 2m19 chain A Region: 1 - 82 Aligned: 82 Modelled: 82 Confidence: 99.8% Identity: 28% PDB header:protein binding Chain: A: PDB Molecule:molybdopterin converting factor subunit 1; PDBTitle: solution structure of the haloferax volcanii hvo 2177 protein Phyre2 PDB 2qie chain B Region: 4 - 82 Aligned: 77 Modelled: 79 Confidence: 99.8% Identity: 39% PDB header:transferase Chain: B: PDB Molecule:molybdopterin synthase small subunit; PDBTitle: staphylococcus aureus molybdopterin synthase in complex with precursor2 z Phyre2 PDB 1fm0 chain D Region: 4 - 82 Aligned: 78 Modelled: 79 Confidence: 99.8% Identity: 31% Fold: beta-Grasp (ubiquitin-like) Superfamily: MoaD/ThiS Family: MoaD Phyre2 PDB 1vjk chain A Region: 2 - 79 Aligned: 78 Modelled: 78 Confidence: 99.8% Identity: 31% Fold: beta-Grasp (ubiquitin-like) Superfamily: MoaD/ThiS Family: MoaD Phyre2 PDB 2l52 chain A Region: 1 - 82 Aligned: 79 Modelled: 82 Confidence: 99.8% Identity: 32% PDB header:protein binding Chain: A: PDB Molecule:methanosarcina acetivorans samp1 homolog; PDBTitle: solution structure of the small archaeal modifier protein 1 (samp1)2 from methanosarcina acetivorans Phyre2 PDB 2qjl chain A Region: 1 - 82 Aligned: 82 Modelled: 82 Confidence: 99.7% Identity: 24% PDB header:signaling protein Chain: A: PDB Molecule:ubiquitin-related modifier 1; PDBTitle: crystal structure of urm1 Phyre2 1 c2qieA_ 2 c6jbzC_ 3 c2omdB_ 4 c6jc0D_ 5 d1fm0e_ 6 c4ap8A_ 7 c3rpfB_ 8 c2wp4A_ 9 d1nvja_ 10 c1v8cA_ 11 c6jbzD_ 12 c6jc0A_ 13 c5mpoA_ 14 c3po0A_ 15 c2m19A_ 16 c2qieB_ 17 d1fm0d_ 18 d1vjka_ 19 c2l52A_ 20 c2qjlA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248