1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	G	E	L	A	E	P	G	V	L	D	R	L	R	A	R	F	G	W	L	D	H	V	V	R	A	F	T	R	F	N	D	R	N	G	S	L	F	A	A	G	L	T	Y	Y	T	I	F	A	I	F	P	L	L	M	V	G	F	G	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	G	F	A	L	S	R	R	P	E	L	L	T	T	L	E	E	R	I	R	T	S	V	S	G	A	V	G	Q	Q	L	V	D	L	M	N	S	A	I	D	A	R	A	S	V	G	V	I	G	L	A	T	A	A	W	V	G	L	G	W
Secondary structure
SS confidence
Disorder																																									?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		M	W	H	L	R	E	A	L	S	Q	M	W	A	H	P	V	A	P	A	G	Y	L	R	T	K	L	S	D	L	A	A	M	V	G	T	F	V	V	I	V	A	T	I	A	L	T	V	L	G	H	A	R	P	M	A	A	V	L	R	W
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	E	I	P	Q	F	S	V	F	D	E	I	F	R	G	I	S	V	L	V	S	V	L	V	S	W	V	L	F	T	W	M	I	G	R	L	P	R	E	P	V	G	L	V	T	A	A	R	A	G	L	M	A	A	V	G	F	E	L	F
Secondary structure
SS confidence
Disorder				?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.
Sequence		K	Q	V	G	A	I	Y	L	Q	I	V	L	R	S	P	A	G	A	V	F	G	P	V	L	G	L	M	V	F	A	F	V	T	A	W	L	I	L	F	A	T	A	W	A	A	T	A	S	A
Secondary structure
SS confidence
Disorder																																															?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 7%) Alpha helix ( 85%) Beta strand ( 0%) TM helix ( 48%) (View membrane topology prediction)

Rank Aligned region

PDB 2r6g chain F domain 1 Region: 198 - 255 Aligned: 57 Modelled: 58 Confidence: 51.3% Identity: 16% Fold: MalF N-terminal region-like Superfamily: MalF N-terminal region-like Family: MalF N-terminal region-like Phyre2 PDB 5mb9 chain C Region: 3 - 18 Aligned: 16 Modelled: 16 Confidence: 19.8% Identity: 31% PDB header:chaperone Chain: C: PDB Molecule:putative ribosome associated protein; PDBTitle: crystal structure of the eukaryotic ribosome associated complex (rac),2 a unique hsp70/hsp40 pair Phyre2 PDB 2qks chain A Region: 191 - 277 Aligned: 87 Modelled: 87 Confidence: 19.4% Identity: 13% PDB header:metal transport Chain: A: PDB Molecule:kir3.1-prokaryotic kir channel chimera; PDBTitle: crystal structure of a kir3.1-prokaryotic kir channel chimera Phyre2 PDB 5mb9 chain D Region: 3 - 18 Aligned: 16 Modelled: 16 Confidence: 18.5% Identity: 31% PDB header:chaperone Chain: D: PDB Molecule:putative ribosome associated protein; PDBTitle: crystal structure of the eukaryotic ribosome associated complex (rac),2 a unique hsp70/hsp40 pair Phyre2 PDB 1xl6 chain B Region: 191 - 277 Aligned: 87 Modelled: 87 Confidence: 15.6% Identity: 8% PDB header:metal transport Chain: B: PDB Molecule:inward rectifier potassium channel; PDBTitle: intermediate gating structure 2 of the inwardly rectifying k+ channel2 kirbac3.1 Phyre2 PDB 1ail chain A Region: 1 - 21 Aligned: 21 Modelled: 21 Confidence: 10.1% Identity: 38% Fold: S15/NS1 RNA-binding domain Superfamily: S15/NS1 RNA-binding domain Family: N-terminal, RNA-binding domain of nonstructural protein NS1 Phyre2 PDB 4atb chain C Region: 1 - 34 Aligned: 34 Modelled: 34 Confidence: 9.5% Identity: 29% PDB header:immune system Chain: C: PDB Molecule:interleukin enhancer-binding factor 2; PDBTitle: crystal structure of the nf90-nf45 dimerisation domain2 complex with ctp Phyre2 PDB 5ec0 chain A Region: 2 - 48 Aligned: 31 Modelled: 31 Confidence: 9.1% Identity: 35% PDB header:structural protein Chain: A: PDB Molecule:alp7a; PDBTitle: crystal structure of actin-like protein alp7a Phyre2 PDB 2h9d chain A domain 1 Region: 1 - 16 Aligned: 16 Modelled: 16 Confidence: 9.0% Identity: 19% Fold: Chorismate mutase II Superfamily: Chorismate mutase II Family: Dimeric chorismate mutase Phyre2 PDB 5lnk chain W Region: 42 - 68 Aligned: 27 Modelled: 27 Confidence: 8.8% Identity: 15% PDB header:oxidoreductase Chain: W: PDB Molecule:mitochondrial complex i, sgdh subunit; PDBTitle: entire ovine respiratory complex i Phyre2 PDB 4o9l chain A Region: 9 - 29 Aligned: 21 Modelled: 21 Confidence: 8.8% Identity: 29% PDB header:antiviral protein Chain: A: PDB Molecule:mitochondrial antiviral signaling protein (mavs); PDBTitle: crystal structure of horse mavs card domain mutant e26r Phyre2 PDB 6cfw chain D Region: 194 - 240 Aligned: 47 Modelled: 47 Confidence: 8.6% Identity: 11% PDB header:membrane protein Chain: D: PDB Molecule:mbh subunit; PDBTitle: cryoem structure of a respiratory membrane-bound hydrogenase Phyre2 PDB 1w8x chain P Region: 256 - 272 Aligned: 17 Modelled: 17 Confidence: 8.6% Identity: 12% PDB header:virus Chain: P: PDB Molecule:protein p16; PDBTitle: structural analysis of prd1 Phyre2 PDB 1p0l chain A Region: 117 - 138 Aligned: 22 Modelled: 19 Confidence: 8.3% Identity: 14% PDB header:ribosome Chain: A: PDB Molecule:19-mer peptide from 50s ribosomal protein l1; PDBTitle: hp (2-20) substitution gln to trp modification in sds-d252 micelles Phyre2 PDB 5lnk chain 2 Region: 8 - 52 Aligned: 45 Modelled: 45 Confidence: 7.9% Identity: 22% PDB header:oxidoreductase Chain: 2: PDB Molecule:mitochondrial complex i, 24 kda subunit; PDBTitle: entire ovine respiratory complex i Phyre2 PDB 4z3p chain A Region: 71 - 272 Aligned: 192 Modelled: 202 Confidence: 7.8% Identity: 13% PDB header:transport protein Chain: A: PDB Molecule:putative drug/sodium antiporter; PDBTitle: mate transporter clbm in complex with rb+ Phyre2 PDB 2m6x chain C Region: 272 - 284 Aligned: 13 Modelled: 13 Confidence: 7.7% Identity: 23% PDB header:membrane protein Chain: C: PDB Molecule:p7; PDBTitle: structure of the p7 channel of hepatitis c virus, genotype 5a Phyre2 PDB 4iu8 chain A Region: 3 - 27 Aligned: 25 Modelled: 25 Confidence: 7.5% Identity: 4% PDB header:transport protein Chain: A: PDB Molecule:nitrite extrusion protein 2; PDBTitle: crystal structure of a membrane transporter (selenomethionine2 derivative) Phyre2 PDB 3p5n chain A Region: 198 - 277 Aligned: 76 Modelled: 80 Confidence: 7.4% Identity: 4% PDB header:transport protein Chain: A: PDB Molecule:riboflavin uptake protein; PDBTitle: structure and mechanism of the s component of a bacterial ecf2 transporter Phyre2 PDB 5kq4 chain C Region: 2 - 17 Aligned: 16 Modelled: 16 Confidence: 7.1% Identity: 25% PDB header:hydrolase Chain: C: PDB Molecule:proline-rich nuclear receptor coactivator 2; PDBTitle: crystal structure of s. pombe dcp1/dcp2 in complex with h. sapiens2 pnrc2 and synthetic cap analog Phyre2 1 d2r6gf1 2 c5mb9C_ 3 c2qksA_ 4 c5mb9D_ 5 c1xl6B_ 6 d1aila_ 7 c4atbC_ 8 c5ec0A_ 9 d2h9da1 10 c5lnkW_ 11 c4o9lA_ 12 c6cfwD_ 13 c1w8xP_ 14 c1p0lA_ 15 c5lnk2_ 16 c4z3pA_ 17 c2m6xC_ 18 c4iu8A_ 19 c3p5nA_ 20 c5kq4C_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54