1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	R	P	H	P	P	V	L	T	V	R	S	D	R	S	Q	Q	C	F	A	A	G	R	D	V	V	V	G	S	D	L	R	A	D	M	R	V	A	H	P	L	I	A	R	A	H	L	L	L	R	F	D	R	G	N	W	I	A	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?										?	?				?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	N	D	S	Q	S	G	M	F	V	D	G	Q	R	V	S	E	V	D	I	Y	D	G	L	T	I	N	I	G	K	P	T	G	P	W	I	T	F	E	V	G	H	H	Q	G	I	I	G	R	L	S	R	T	P	S	S	R	P	G	S
Secondary structure
SS confidence
Disorder																																										?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.
Sequence		P	I
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 27%) Alpha helix ( 0%) Beta strand ( 45%)

Rank Aligned region

PDB 6ccd chain A Region: 5 - 101 Aligned: 97 Modelled: 97 Confidence: 100.0% Identity: 64% PDB header:protein binding Chain: A: PDB Molecule:abc transporter atp-binding/permease protein rv1747; PDBTitle: the crystal structure of mycobacterium tuberculosis rv1747 fha-1 Phyre2 PDB 2kkl chain A Region: 4 - 106 Aligned: 100 Modelled: 103 Confidence: 99.9% Identity: 22% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein mb1858; PDBTitle: solution nmr structure of fha domain of mb1858 from2 mycobacterium bovis. northeast structural genomics3 consortium target mbr243c (24-155). Phyre2 PDB 2kfu chain A Region: 4 - 114 Aligned: 108 Modelled: 111 Confidence: 99.9% Identity: 20% PDB header:protein binding Chain: A: PDB Molecule:rv1827 pthr 22; PDBTitle: pknb-phosphorylated rv1827 Phyre2 PDB 2n84 chain A Region: 5 - 106 Aligned: 101 Modelled: 102 Confidence: 99.9% Identity: 20% PDB header:isomerase Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution structure of the fha domain of tbpar42 Phyre2 PDB 6cah chain A Region: 1 - 99 Aligned: 96 Modelled: 99 Confidence: 99.9% Identity: 24% PDB header:protein binding Chain: A: PDB Molecule:abc transporter atp-binding/permease protein rv1747; PDBTitle: nmr-based structure of the fha-2 domain from mycobacterium2 tuberculosis abc transporter rv1747 Phyre2 PDB 3hx1 chain B Region: 8 - 100 Aligned: 91 Modelled: 93 Confidence: 99.8% Identity: 22% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:slr1951 protein; PDBTitle: crystal structure of the slr1951 protein from synechocystis sp.2 northeast structural genomics consortium target sgr167a Phyre2 PDB 4jon chain A Region: 10 - 109 Aligned: 99 Modelled: 100 Confidence: 99.8% Identity: 14% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:centrosomal protein of 170 kda; PDBTitle: crystal structure of a centrosomal protein 170kda, transcript variant2 beta (cep170) from homo sapiens at 2.15 a resolution (psi community3 target, sundstrom) Phyre2 PDB 1mzk chain A Region: 23 - 103 Aligned: 81 Modelled: 81 Confidence: 99.8% Identity: 17% Fold: SMAD/FHA domain Superfamily: SMAD/FHA domain Family: FHA domain Phyre2 PDB 3vpy chain A Region: 4 - 106 Aligned: 100 Modelled: 103 Confidence: 99.8% Identity: 17% PDB header:protein binding Chain: A: PDB Molecule:fha domain-containing protein ddl; PDBTitle: crystal structure of arabidopsis ddl fha domain Phyre2 PDB 1uht chain A Region: 2 - 105 Aligned: 104 Modelled: 104 Confidence: 99.8% Identity: 25% Fold: SMAD/FHA domain Superfamily: SMAD/FHA domain Family: FHA domain Phyre2 PDB 2ff4 chain A domain 3 Region: 2 - 102 Aligned: 97 Modelled: 101 Confidence: 99.8% Identity: 21% Fold: SMAD/FHA domain Superfamily: SMAD/FHA domain Family: FHA domain Phyre2 PDB 5a8i chain A Region: 20 - 104 Aligned: 85 Modelled: 85 Confidence: 99.8% Identity: 22% PDB header:transcription Chain: A: PDB Molecule:arna; PDBTitle: crystal structure of the fha domain of arna from sulfolobus2 acidocaldarius Phyre2 PDB 3poa chain A Region: 8 - 100 Aligned: 90 Modelled: 93 Confidence: 99.8% Identity: 22% PDB header:peptide binding protein Chain: A: PDB Molecule:putative uncharacterized protein tb39.8; PDBTitle: structural and functional analysis of phosphothreonine-dependent fha2 domain interactions Phyre2 PDB 2jkd chain B Region: 16 - 103 Aligned: 88 Modelled: 88 Confidence: 99.8% Identity: 17% PDB header:gene regulation Chain: B: PDB Molecule:pre-mrna leakage protein 1; PDBTitle: structure of the yeast pml1 splicing factor and its2 integration into the res complex Phyre2 PDB 2jql chain A Region: 3 - 106 Aligned: 102 Modelled: 104 Confidence: 99.8% Identity: 19% PDB header:cell cycle Chain: A: PDB Molecule:dna damage response protein kinase dun1; PDBTitle: nmr structure of the yeast dun1 fha domain in complex with2 a doubly phosphorylated (pt) peptide derived from rad533 scd1 Phyre2 PDB 3els chain A Region: 16 - 92 Aligned: 77 Modelled: 77 Confidence: 99.8% Identity: 16% PDB header:splicing Chain: A: PDB Molecule:pre-mrna leakage protein 1; PDBTitle: crystal structure of yeast pml1p, residues 51-204 Phyre2 PDB 4h87 chain A Region: 2 - 100 Aligned: 96 Modelled: 99 Confidence: 99.8% Identity: 19% PDB header:peptide binding protein Chain: A: PDB Molecule:kanadaptin; PDBTitle: crystal structure of a fha domain of kanadaptin (slc4a1ap) from homo2 sapiens at 1.55 a resolution Phyre2 PDB 3oun chain A Region: 6 - 100 Aligned: 90 Modelled: 95 Confidence: 99.8% Identity: 22% PDB header:protein binding/transferase Chain: A: PDB Molecule:putative uncharacterized protein tb39.8; PDBTitle: crystal structure of the fhaa fha domain complexed with the2 intracellular domain of rv3910 Phyre2 PDB 5yyx chain A Region: 4 - 100 Aligned: 94 Modelled: 97 Confidence: 99.8% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:meiosis-specific serine/threonine-protein kinase mek1; PDBTitle: crystal structure of the mek1 fha domain Phyre2 PDB 6ar2 chain B Region: 4 - 89 Aligned: 86 Modelled: 86 Confidence: 99.8% Identity: 24% PDB header:membrane protein Chain: B: PDB Molecule:sarcolemmal membrane-associated protein; PDBTitle: structure of human slmap fha domain in complex with pmst2 Phyre2 1 c6ccdA_ 2 c2kklA_ 3 c2kfuA_ 4 c2n84A_ 5 c6cahA_ 6 c3hx1B_ 7 c4jonA_ 8 d1mzka_ 9 c3vpyA_ 10 d1uhta_ 11 d2ff4a3 12 c5a8iA_ 13 c3poaA_ 14 c2jkdB_ 15 c2jqlA_ 16 c3elsA_ 17 c4h87A_ 18 c3ounA_ 19 c5yyxA_ 20 c6ar2B_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99