1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	F	R	T	V	G	D	Q	A	S	L	W	E	S	V	L	P	E	E	L	R	R	L	P	E	E	L	A	R	V	D	A	L	L	D	D	S	A	F	F	C	P	F	V	P	F	F	D	P	R	M	G	R	P	S	I	P	M	E	T
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																											?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Y	L	R	L	M	F	L	K	F	R	Y	R	L	G	Y	E	S	L	C	R	E	V	T	D	S	I	T	W	R	R	F	C	R	I	P	L	E	G	S	V	P	H	P	T	T	L	M	K	L	T	T	R	C	G	E	D	A	V	A	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	N	E	A	L	L	A	K	A	A	S	E	K	L	L	R	T	N	K	V	R	A	D	T	T	V	V	E	G	D	V	G	Y	P	T	D	T	G	L	L	A	K	A	V	G	S	M	A	R	T	V	A	R	I	K	A	A	D	A	G
Secondary structure
SS confidence
Disorder																?		?	?														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.
Sequence		S	A	P	L	G	G	S	S	G	P	R	D	R	L	Q	A	A	V	T	R	R	A	A	T	R	S	G	A	G	L	R	A	P	D	H	R	G	A	S	R	D	R	R	A	G	A	D	R	G	C	R	G	G	T
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?		?																?	?	?	?	?	?	?	?	?							?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 20%) Alpha helix ( 64%) Beta strand ( 3%)

Rank Aligned region

PDB 1slm chain A domain 1 Region: 66 - 106 Aligned: 37 Modelled: 41 Confidence: 62.5% Identity: 19% Fold: PGBD-like Superfamily: PGBD-like Family: MMP N-terminal domain Phyre2 PDB 1bg1 chain A Region: 34 - 109 Aligned: 65 Modelled: 76 Confidence: 44.7% Identity: 17% PDB header:transcription/dna Chain: A: PDB Molecule:protein (transcription factor stat3b); PDBTitle: transcription factor stat3b/dna complex Phyre2 PDB 3hef chain B Region: 76 - 132 Aligned: 54 Modelled: 57 Confidence: 44.2% Identity: 15% PDB header:viral protein Chain: B: PDB Molecule:gene 1 protein; PDBTitle: crystal structure of the bacteriophage sf6 terminase small subunit Phyre2 PDB 5wtn chain B Region: 34 - 83 Aligned: 47 Modelled: 47 Confidence: 42.6% Identity: 19% PDB header:replication Chain: B: PDB Molecule:replication initiation and membrane attachment protein; PDBTitle: crystal structure analysis of primosome protein dnab (resiues 1-300)2 from geobacillus stearothermophilus Phyre2 PDB 1yvl chain B Region: 34 - 137 Aligned: 88 Modelled: 99 Confidence: 36.5% Identity: 13% PDB header:signaling protein Chain: B: PDB Molecule:signal transducer and activator of transcription PDBTitle: structure of unphosphorylated stat1 Phyre2 PDB 6rao chain I Region: 35 - 103 Aligned: 69 Modelled: 69 Confidence: 35.3% Identity: 13% PDB header:virus like particle Chain: I: PDB Molecule:afp11; PDBTitle: cryo-em structure of the anti-feeding prophage (afp) baseplate, 6-fold2 symmetrised Phyre2 PDB 1bg1 chain A domain 2 Region: 34 - 109 Aligned: 66 Modelled: 76 Confidence: 27.8% Identity: 18% Fold: Common fold of diphtheria toxin/transcription factors/cytochrome f Superfamily: p53-like transcription factors Family: STAT DNA-binding domain Phyre2 PDB 1eak chain A domain 1 Region: 66 - 114 Aligned: 48 Modelled: 49 Confidence: 25.5% Identity: 21% Fold: PGBD-like Superfamily: PGBD-like Family: MMP N-terminal domain Phyre2 PDB 1bf5 chain A Region: 34 - 137 Aligned: 78 Modelled: 86 Confidence: 24.7% Identity: 18% PDB header:gene regulation/dna Chain: A: PDB Molecule:signal transducer and activator of transcription 1- PDBTitle: tyrosine phosphorylated stat-1/dna complex Phyre2 PDB 1su3 chain A domain 1 Region: 66 - 106 Aligned: 36 Modelled: 41 Confidence: 24.4% Identity: 22% Fold: PGBD-like Superfamily: PGBD-like Family: MMP N-terminal domain Phyre2 PDB 6g4w chain W Region: 54 - 133 Aligned: 77 Modelled: 80 Confidence: 20.3% Identity: 22% PDB header:ribosome Chain: W: PDB Molecule:40s ribosomal protein s15a; PDBTitle: cryo-em structure of a late human pre-40s ribosomal subunit - state a Phyre2 PDB 3nzq chain B Region: 61 - 103 Aligned: 43 Modelled: 43 Confidence: 19.6% Identity: 12% PDB header:lyase Chain: B: PDB Molecule:biosynthetic arginine decarboxylase; PDBTitle: crystal structure of biosynthetic arginine decarboxylase adc (spea)2 from escherichia coli, northeast structural genomics consortium3 target er600 Phyre2 PDB 1eak chain A Region: 53 - 111 Aligned: 56 Modelled: 59 Confidence: 16.6% Identity: 18% PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:72 kda type iv collagenase; PDBTitle: catalytic domain of prommp-2 e404q mutant Phyre2 PDB 3iwf chain A Region: 66 - 125 Aligned: 60 Modelled: 60 Confidence: 16.1% Identity: 7% PDB header:transcription regulator Chain: A: PDB Molecule:transcription regulator rpir family; PDBTitle: the crystal structure of the n-terminal domain of a rpir2 transcriptional regulator from staphylococcus epidermidis to 1.4a Phyre2 PDB 2p06 chain A Region: 37 - 84 Aligned: 39 Modelled: 48 Confidence: 15.9% Identity: 18% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein af_0060; PDBTitle: crystal structure of a predicted coding region af_0060 from2 archaeoglobus fulgidus dsm 4304 Phyre2 PDB 2p06 chain A domain 1 Region: 37 - 84 Aligned: 39 Modelled: 48 Confidence: 15.9% Identity: 18% Fold: all-alpha NTP pyrophosphatases Superfamily: all-alpha NTP pyrophosphatases Family: AF0060-like Phyre2 PDB 3n2o chain A Region: 9 - 103 Aligned: 91 Modelled: 95 Confidence: 15.9% Identity: 16% PDB header:lyase Chain: A: PDB Molecule:biosynthetic arginine decarboxylase; PDBTitle: x-ray crystal structure of arginine decarboxylase complexed with2 arginine from vibrio vulnificus Phyre2 PDB 1slm chain A Region: 61 - 114 Aligned: 50 Modelled: 54 Confidence: 15.0% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:stromelysin-1; PDBTitle: crystal structure of fibroblast stromelysin-1: the c-truncated human2 proenzyme Phyre2 PDB 4fmo chain B Region: 45 - 56 Aligned: 11 Modelled: 12 Confidence: 12.7% Identity: 45% PDB header:hydrolase Chain: B: PDB Molecule:dna mismatch repair protein pms1; PDBTitle: structure of the c-terminal domain of the saccharomyces cerevisiae2 mutl alpha (mlh1/pms1) heterodimer bound to a fragment of exo1 Phyre2 PDB 3d3k chain D Region: 54 - 82 Aligned: 29 Modelled: 29 Confidence: 12.5% Identity: 24% PDB header:protein binding Chain: D: PDB Molecule:enhancer of mrna-decapping protein 3; PDBTitle: crystal structure of human edc3p Phyre2 1 d1slma1 2 c1bg1A_ 3 c3hefB_ 4 c5wtnB_ 5 c1yvlB_ 6 c6raoI_ 7 d1bg1a2 8 d1eaka1 9 c1bf5A_ 10 d1su3a1 11 c6g4ww_ 12 c3nzqB_ 13 c1eakA_ 14 c3iwfA_ 15 c2p06A_ 16 d2p06a1 17 c3n2oA_ 18 c1slmA_ 19 c4fmoB_ 20 c3d3kD_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71