Phyre 2 Results for RVBD3388_(PE_PGRS52)_3801833

Email	mdejesus@rockefeller.edu
Description	RVBD3388_(PE_PGRS52)_3801833_3804028
Date	Fri Aug 9 18:20:05 BST 2019
Unique Job ID	dfca1b4600f0c4ad
Sequence	MSFVIANPEM ... Download FASTA
Job Type	normal
Job Expiry

Summary

Top model

Image coloured by rainbow N → C terminus

Model dimensions (Å):

X:40.590 Y:35.740 Z:53.088

Model (left) based on template c5xfsA_

Top template information

PDB header:protein transport
Chain: A: PDB Molecule:pe family protein pe8;
PDBTitle: crystal structure of pe8-ppe15 in complex with espg5 from m.2 tuberculosis

Confidence and coverage

Confidence:

99.3%

Coverage:

11%

77 residues ( 11% of your sequence) have been modelled with 99.3% confidence by the single highest scoring template.

Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.

276 residues ( 38%) could be modelled at >90% confidence using multiple-templates.

You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.

Warning: 92% of your sequence is predicted disordered. Disordered regions cannot be meaningfully predicted.

3D viewing

Interactive 3D view in JSmol

For other options to view your downloaded structure offline see the FAQ

Sequence analysis

Download FASTA version

Secondary structure and disorder prediction [Show]

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M S F V I A N P E M L A A A A T D L A G I R S A I S A A T A A A A A P T I Q V A A A G A D E V S L A I S A L F G Q H A Q

Secondary structure

SS confidence

Disorder ? ? ?
? ?
? ? ? ? ? ? ? ? ? ? ?
? ? ? ?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence A Y Q A L S A Q A T I F H D Q F V Q A L T S G G N L Y A A A E S H T V E Q M V L N A I N A P T Q T L F G R P L I G D G A

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence N G T A E N P D G Q N G G L L F G N G G N G F T Q T T A G V A G G N G G S A G L I G N G G A G G G G G A G A A G G L G G

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240

Sequence N G G W L Y G N G G A G G I G G A G T G T G G H G G A G G A G G R A W L W G T G G A G G A G G D G G W L F G D G G A G G

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280 . . . . . . . . . 290 . . . . . . . . . 300

Sequence T G G N G G S G F N S L T S S V G G A G G A G G H A G L F G A G G T G G T G G I G G Q N T E T G P A A S N G G A G G A G

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350 . . . . . . . . . 360

Sequence G G G G Y L V G D G G A G G T G G A G G K N S S G G A T L T G G T G G T G G A G G A A G W L Y G S G G A G G A G G A G G

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence L N N A G G A T G G T G G T G G A G G S G A W L Y G N G G A A G A G G N G G N N T S A G T G G V G A S G G T G G N A G L

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480

Sequence I G A G G H G G A G G A G G N Q T G G V G N G G A G G N G G A G G A G G Q L Y G N G G D G G N G G A G G A N I A G G N G

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 490 . . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540

Sequence S D G G A A G H G G A G G S A R L I G A G G H G G D G G A G G N T A G R R A D A I A G T G G D G G N G G N G G L L S G N

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 550 . . . . . . . . . 560 . . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600

Sequence A G A G G H G G A G G S S T A T T T T G T P P T G A T G G N G G N G G A G G T A G F T G S G G I G G N G G A G G T G G N

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630 . . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660

Sequence A G V A L S V G S T G G L G G N G G S G G L G G G G G S L F G N G G A G G V G A T G G N G G S G I G P A S V G G N G G K

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700 . . . . . . . . . 710 . . . . . . . . . 720

Sequence G G V G A A G G L A G Q I G N G G S G G S G G A G G N G G T G D T A G N G G N G G A G A V G G N A Q L I G N G G N G G G

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 730 .

Sequence G G N G G T G A D G T

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered ( 92%)

Alpha helix ( 12%)

Beta strand ( 1%)

Domain analysis [Show]

Rank Aligned region

PDB 5xfs chain A

3D model

Region: 8 - 84
Aligned: 77
Modelled: 77
Confidence: 99.3%
Identity: 47%
PDB header:protein transport
Chain: A: PDB Molecule:pe family protein pe8;
PDBTitle: crystal structure of pe8-ppe15 in complex with espg5 from m.2 tuberculosis

Phyre2

PDB 2g38 chain A

3D model

Region: 8 - 84
Aligned: 77
Modelled: 77
Confidence: 99.3%
Identity: 32%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:pe family protein;
PDBTitle: a pe/ppe protein complex from mycobacterium tuberculosis

Phyre2

PDB 2g38 chain A domain 1

3D model

Region: 8 - 84
Aligned: 77
Modelled: 77
Confidence: 99.3%
Identity: 32%
Fold: Ferritin-like
Superfamily: PE/PPE dimer-like
Family: PE

Phyre2

PDB 1k7q chain A

Region: 630 - 729
Aligned: 100
Modelled: 100
Confidence: 98.0%
Identity: 24%
PDB header:hydrolase
Chain: A: PDB Molecule:secreted protease c;
PDBTitle: prtc from erwinia chrysanthemi: e189a mutant

Phyre2

PDB 1kap chain P domain 1

3D model

Region: 622 - 729
Aligned: 108
Modelled: 108
Confidence: 98.0%
Identity: 19%
Fold: Single-stranded right-handed beta-helix
Superfamily: beta-Roll
Family: Serralysin-like metalloprotease, C-terminal domain

Phyre2

PDB 2ml3 chain A

Region: 660 - 729
Aligned: 70
Modelled: 70
Confidence: 97.8%
Identity: 21%
PDB header:isomerase
Chain: A: PDB Molecule:poly(beta-d-mannuronate) c5 epimerase 6;
PDBTitle: solution structure of alge6r3 subunit from the azotobacter vinelandii2 mannuronan c5-epimerase

Phyre2

PDB 2agm chain A

3D model

Region: 671 - 729
Aligned: 59
Modelled: 59
Confidence: 97.8%
Identity: 27%
PDB header:isomerase
Chain: A: PDB Molecule:poly(beta-d-mannuronate) c5 epimerase 4;
PDBTitle: solution structure of the r-module from alge4

Phyre2

PDB 2ml2 chain A

3D model

Region: 660 - 729
Aligned: 70
Modelled: 70
Confidence: 97.8%
Identity: 21%
PDB header:isomerase
Chain: A: PDB Molecule:poly(beta-d-mannuronate) c5 epimerase 6;
PDBTitle: solution structure of alge6r2 subunit from the azotobacter vinelandii2 mannuronan c5-epimerase

Phyre2

PDB 1k7i chain A domain 1

3D model

Region: 659 - 729
Aligned: 71
Modelled: 71
Confidence: 97.8%
Identity: 28%
Fold: Single-stranded right-handed beta-helix
Superfamily: beta-Roll
Family: Serralysin-like metalloprotease, C-terminal domain

Phyre2

PDB 2zj6 chain A

Region: 672 - 729
Aligned: 58
Modelled: 58
Confidence: 97.8%
Identity: 26%
PDB header:hydrolase
Chain: A: PDB Molecule:lipase;
PDBTitle: crystal structure of d337a mutant of pseudomonas sp. mis38 lipase

Phyre2

PDB 1jiw chain P

3D model

Region: 661 - 729
Aligned: 69
Modelled: 69
Confidence: 97.6%
Identity: 28%
PDB header:hydrolase/hyrolase inhibitor
Chain: P: PDB Molecule:alkaline metalloproteinase;
PDBTitle: crystal structure of the apr-aprin complex

Phyre2

PDB 1om8 chain A

3D model

Region: 659 - 729
Aligned: 71
Modelled: 71
Confidence: 97.4%
Identity: 25%
PDB header:hydrolase
Chain: A: PDB Molecule:serralysin;
PDBTitle: crystal structure of a cold adapted alkaline protease from pseudomonas2 tac ii 18, co-crystallyzed with 10 mm edta

Phyre2

PDB 2qub chain G

3D model

Region: 531 - 729
Aligned: 198
Modelled: 199
Confidence: 97.3%
Identity: 17%
PDB header:hydrolase
Chain: G: PDB Molecule:extracellular lipase;
PDBTitle: crystal structure of extracellular lipase lipa from serratia2 marcescens

Phyre2

PDB 1sat chain A

3D model

Region: 659 - 729
Aligned: 71
Modelled: 71
Confidence: 97.2%
Identity: 25%
PDB header:hydrolase (serine protease)
Chain: A: PDB Molecule:serratia protease;
PDBTitle: crystal structure of the 50 kda metallo protease from s.2 marcescens

Phyre2

PDB 1g9k chain A domain 1

3D model

Region: 615 - 729
Aligned: 115
Modelled: 115
Confidence: 96.7%
Identity: 19%
Fold: Single-stranded right-handed beta-helix
Superfamily: beta-Roll
Family: Serralysin-like metalloprotease, C-terminal domain

Phyre2

PDB 5cxl chain A

Region: 679 - 729
Aligned: 51
Modelled: 51
Confidence: 96.4%
Identity: 25%
PDB header:toxin
Chain: A: PDB Molecule:bifunctional hemolysin/adenylate cyclase;
PDBTitle: crystal structure of rtx domain block v of adenylate cyclase toxin2 from bordetella pertussis

Phyre2

PDB 3p4g chain D

3D model

Region: 659 - 729
Aligned: 71
Modelled: 71
Confidence: 96.4%
Identity: 13%
PDB header:antifreeze protein
Chain: D: PDB Molecule:antifreeze protein;
PDBTitle: x-ray crystal structure of a hyperactive, ca2+-dependent, beta-helical2 antifreeze protein from an antarctic bacterium

Phyre2

PDB 1sat chain A domain 1

3D model

Region: 613 - 729
Aligned: 117
Modelled: 117
Confidence: 96.1%
Identity: 21%
Fold: Single-stranded right-handed beta-helix
Superfamily: beta-Roll
Family: Serralysin-like metalloprotease, C-terminal domain

Phyre2

PDB 4q1q chain A

Region: 686 - 729
Aligned: 44
Modelled: 44
Confidence: 78.0%
Identity: 18%
PDB header:cell adhesion
Chain: A: PDB Molecule:adhesin/invasin tiba autotransporter;
PDBTitle: crystal structure of tibc-catalyzed hyper-glycosylated tiba55-3502 fragment

Phyre2

PDB 5juh chain A

3D model

Region: 685 - 720
Aligned: 36
Modelled: 36
Confidence: 46.9%
Identity: 22%
PDB header:cell adhesion
Chain: A: PDB Molecule:antifreeze protein;
PDBTitle: crystal structure of c-terminal domain (rv) of mpafp

Phyre2

1
c5xfsA_

2
c2g38A_

3
d2g38a1

4
c1k7qA_

5
d1kapp1

6
c2ml3A_

7
c2agmA_

8
c2ml2A_

9
d1k7ia1

10
c2zj6A_

11
c1jiwP_

12
c1om8A_

13
c2qubG_

14
c1satA_

15
d1g9ka1

16
c5cxlA_

17
c3p4gD_

18
d1sata1

19
c4q1qA_

20
c5juhA_

21

22

23