1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	N	E	T	P	H	A	P	V	V	E	Q	V	L	V	A	A	A	F	G	N	Q	P	G	S	W	P	L	P	T	A	I	T	P	H	H	L	W	L	R	A	V	A	A	G	G	Q	G	R	Y	A	H	A	Y	G	D	L	S	V	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?								?																																									?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	R	L	V	P	A	G	P	L	A	S	L	A	H	S	T	Q	G	S	L	L	R	Q	L	G	W	H	T	L	A	R	G	W	D	G	R	A	L	A	L	A	G	A	D	R	E	A	G	A	D	A	L	I	G	L	A	A	D	A	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																																			?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	V	G	R	F	A	A	A	G	A	L	L	D	R	A	D	P	L	V	V	S	P	L	V	A	D	R	L	A	V	R	R	R	W	V	A	A	E	L	A	M	A	T	G	D	G	A	T	A	V	R	H	A	E	E	A	V	E	L	T
Secondary structure
SS confidence
Disorder																					?	?																								?	?	?	?	?	?	?	?							?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Q	A	M	A	V	A	S	A	R	H	R	V	K	S	D	V	V	L	A	A	A	L	C	S	A	G	A	V	A	R	A	R	A	V	G	E	E	A	L	D	A	T	A	R	F	G	L	L	P	L	R	W	A	L	A	C	L	L	I	D
Secondary structure
SS confidence
Disorder				?	?	?	?	?	?						?										?	?	?	?	?	?	?																													?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.
Sequence		I	G	T	V	T	F	S	A	Q	Q	L	R	E	L	T	K	I	R	N	I	C	A	G	Q	V	R	R	A	G	G	C	W	R	T	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?																				?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 24%) Alpha helix ( 76%) Beta strand ( 0%)

Rank Aligned region

PDB 6mfv chain C Region: 34 - 241 Aligned: 204 Modelled: 208 Confidence: 96.4% Identity: 12% PDB header:signaling protein Chain: C: PDB Molecule:tetratricopeptide repeat sensor ph0952; PDBTitle: crystal structure of the signal transduction atpase with numerous2 domains (stand) protein with a tetratricopeptide repeat sensor ph09523 from pyrococcus horikoshii Phyre2 PDB 5khr chain O Region: 57 - 241 Aligned: 183 Modelled: 183 Confidence: 90.5% Identity: 21% PDB header:cell cycle Chain: O: PDB Molecule:anaphase-promoting complex subunit 5; PDBTitle: model of human anaphase-promoting complex/cyclosome complex (apc152 deletion mutant) in complex with the e2 ube2c/ubch10 poised for3 ubiquitin ligation to substrate (apc/c-cdc20-substrate-ube2c) Phyre2 PDB 1hz4 chain A Region: 39 - 239 Aligned: 198 Modelled: 201 Confidence: 43.7% Identity: 17% Fold: alpha-alpha superhelix Superfamily: TPR-like Family: Transcription factor MalT domain III Phyre2 PDB 2n8i chain A Region: 163 - 226 Aligned: 62 Modelled: 64 Confidence: 42.1% Identity: 11% PDB header:de novo protein Chain: A: PDB Molecule:designed protein da05; PDBTitle: solution nmr structure of designed protein da05, northeast structural2 genomics consortium (nesg) target or626 Phyre2 PDB 3qky chain A Region: 31 - 93 Aligned: 63 Modelled: 63 Confidence: 32.4% Identity: 19% PDB header:membrane protein Chain: A: PDB Molecule:outer membrane assembly lipoprotein yfio; PDBTitle: crystal structure of rhodothermus marinus bamd Phyre2 PDB 4ui9 chain O Region: 68 - 272 Aligned: 200 Modelled: 205 Confidence: 31.8% Identity: 18% PDB header:cell cycle Chain: O: PDB Molecule:anaphase-promoting complex subunit 5; PDBTitle: atomic structure of the human anaphase-promoting complex Phyre2 PDB 3gw4 chain B Region: 48 - 226 Aligned: 174 Modelled: 179 Confidence: 20.9% Identity: 20% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein from deinococcus2 radiodurans. northeast structural genomics consortium target drr162b. Phyre2 PDB 3hmj chain B Region: 43 - 60 Aligned: 18 Modelled: 18 Confidence: 14.5% Identity: 33% PDB header:transferase Chain: B: PDB Molecule:fatty acid synthase subunit alpha; PDBTitle: saccharomyces cerevisiae fas type i Phyre2 PDB 3h87 chain D Region: 58 - 72 Aligned: 15 Modelled: 15 Confidence: 13.2% Identity: 53% PDB header:toxin/antitoxin Chain: D: PDB Molecule:putative uncharacterized protein; PDBTitle: rv0301 rv0300 toxin antitoxin complex from mycobacterium tuberculosis Phyre2 PDB 2uv9 chain B Region: 43 - 60 Aligned: 18 Modelled: 18 Confidence: 10.9% Identity: 28% PDB header:transferase Chain: B: PDB Molecule:fatty acid synthase alpha subunits; PDBTitle: crystal structure of fatty acid synthase from thermomyces2 lanuginosus at 3.1 angstrom resolution. this file contains3 the alpha subunits of the fatty acid synthase. the entire4 crystal structure consists of one heterododecameric fatty5 acid synthase and is described in remark 400 Phyre2 PDB 4b3y chain B Region: 43 - 60 Aligned: 18 Modelled: 18 Confidence: 10.7% Identity: 39% PDB header:transferase Chain: B: PDB Molecule:fatty acid synthase; PDBTitle: cryo-em structure of the mycobacterial fatty acid synthase Phyre2 PDB 2uv8 chain C Region: 43 - 60 Aligned: 18 Modelled: 18 Confidence: 10.0% Identity: 33% PDB header:transferase Chain: C: PDB Molecule:fatty acid synthase subunit alpha (fas2); PDBTitle: crystal structure of yeast fatty acid synthase with stalled2 acyl carrier protein at 3.1 angstrom resolution Phyre2 PDB 2vkz chain C Region: 43 - 60 Aligned: 18 Modelled: 18 Confidence: 7.4% Identity: 33% PDB header:transferase Chain: C: PDB Molecule:fatty acid synthase subunit alpha; PDBTitle: structure of the cerulenin-inhibited fungal fatty acid synthase type i2 multienzyme complex Phyre2 PDB 4u4c chain B Region: 42 - 50 Aligned: 9 Modelled: 9 Confidence: 6.0% Identity: 67% PDB header:hydrolase Chain: B: PDB Molecule:protein air2,poly(a) rna polymerase protein 2; PDBTitle: the molecular architecture of the tramp complex reveals the2 organization and interplay of its two catalytic activities Phyre2 PDB 2pff chain D Region: 43 - 60 Aligned: 18 Modelled: 18 Confidence: 6.0% Identity: 33% PDB header:transferase Chain: D: PDB Molecule:fatty acid synthase subunit alpha; PDBTitle: structural insights of yeast fatty acid synthase Phyre2 PDB 2pff chain G Region: 43 - 60 Aligned: 18 Modelled: 18 Confidence: 6.0% Identity: 33% PDB header:transferase Chain: G: PDB Molecule:fatty acid synthase subunit alpha; PDBTitle: structural insights of yeast fatty acid synthase Phyre2 PDB 2pff chain A Region: 43 - 60 Aligned: 18 Modelled: 18 Confidence: 6.0% Identity: 33% PDB header:transferase Chain: A: PDB Molecule:fatty acid synthase subunit alpha; PDBTitle: structural insights of yeast fatty acid synthase Phyre2 PDB 1gx5 chain A Region: 58 - 89 Aligned: 32 Modelled: 32 Confidence: 5.9% Identity: 31% Fold: DNA/RNA polymerases Superfamily: DNA/RNA polymerases Family: RNA-dependent RNA-polymerase Phyre2 PDB 2gbb chain A Region: 207 - 229 Aligned: 23 Modelled: 23 Confidence: 5.3% Identity: 17% PDB header:isomerase Chain: A: PDB Molecule:putative chorismate mutase; PDBTitle: crystal structure of secreted chorismate mutase from yersinia pestis Phyre2 1 c6mfvC_ 2 c5khrO_ 3 d1hz4a_ 4 c2n8iA_ 5 c3qkyA_ 6 c4ui9O_ 7 c3gw4B_ 8 c3hmjB_ 9 c3h87D_ 10 c2uv9B_ 11 c4b3yB_ 12 c2uv8C_ 13 c2vkzC_ 14 c4u4cB_ 15 c2pffD_ 16 c2pffG_ 17 c2pffA_ 18 d1gx5a_ 19 c2gbbA_