1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	H	P	M	I	P	A	E	Y	I	S	N	I	I	Y	E	G	P	G	A	D	S	L	S	A	A	A	E	Q	L	R	L	M	Y	N	S	A	N	M	T	A	K	S	L	T	D	R	L	G	E	L	Q	E	N	W	K	G	S	S	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																																													?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	L	M	A	D	A	A	G	R	Y	L	D	W	L	T	K	H	S	R	Q	I	L	E	T	A	Y	V	I	D	F	L	A	Y	V	Y	E	E	T	R	H	K	V	V	P	P	A	T	I	A	N	N	R	E	E	V	H	R	L	I	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.
Sequence		S	N	V	A	G	V	N	T	P	A	I	A	G	L	D	A	Q	Y	Q	Q	Y	R	A	Q	N	I	A	V	M	N	D	Y	Q	S	T	A	R	F	I	L	A	Y	L	P	R	W	Q	E	P	P	Q	I	Y	G	G	G	G	G
Secondary structure
SS confidence
Disorder																																										?	?	?	?	?		?	?		?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 15%) Alpha helix ( 76%) Beta strand ( 0%)

Rank Aligned region

PDB 2g38 chain B domain 1 Region: 2 - 173 Aligned: 172 Modelled: 172 Confidence: 100.0% Identity: 34% Fold: Ferritin-like Superfamily: PE/PPE dimer-like Family: PPE Phyre2 PDB 2g38 chain B Region: 2 - 173 Aligned: 172 Modelled: 172 Confidence: 100.0% Identity: 34% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:ppe family protein; PDBTitle: a pe/ppe protein complex from mycobacterium tuberculosis Phyre2 PDB 5xfs chain B Region: 2 - 172 Aligned: 170 Modelled: 171 Confidence: 100.0% Identity: 31% PDB header:protein transport Chain: B: PDB Molecule:ppe family protein ppe15; PDBTitle: crystal structure of pe8-ppe15 in complex with espg5 from m.2 tuberculosis Phyre2 PDB 4xy3 chain A Region: 3 - 172 Aligned: 154 Modelled: 170 Confidence: 100.0% Identity: 15% PDB header:protein transport Chain: A: PDB Molecule:esx-1 secretion-associated protein espb; PDBTitle: structure of esx-1 secreted protein espb Phyre2 PDB 4wj2 chain A Region: 3 - 176 Aligned: 153 Modelled: 162 Confidence: 99.2% Identity: 14% PDB header:unknown function Chain: A: PDB Molecule:antigen mtb48; PDBTitle: mycobacterial protein Phyre2 PDB 2vs0 chain B Region: 20 - 98 Aligned: 79 Modelled: 79 Confidence: 98.3% Identity: 15% PDB header:cell invasion Chain: B: PDB Molecule:virulence factor esxa; PDBTitle: structural analysis of homodimeric staphylococcal aureus2 virulence factor esxa Phyre2 PDB 3gvm chain A Region: 20 - 98 Aligned: 79 Modelled: 79 Confidence: 98.2% Identity: 18% PDB header:viral protein Chain: A: PDB Molecule:putative uncharacterized protein sag1039; PDBTitle: structure of the homodimeric wxg-100 family protein from streptococcus2 agalactiae Phyre2 PDB 3zbh chain C Region: 20 - 98 Aligned: 79 Modelled: 79 Confidence: 98.1% Identity: 19% PDB header:unknown function Chain: C: PDB Molecule:esxa; PDBTitle: geobacillus thermodenitrificans esxa crystal form i Phyre2 PDB 4iog chain D Region: 20 - 97 Aligned: 78 Modelled: 78 Confidence: 98.1% Identity: 10% PDB header:unknown function Chain: D: PDB Molecule:secreted protein esxb; PDBTitle: the crystal structure of a secreted protein esxb (wild-type, in p212 space group) from bacillus anthracis str. sterne Phyre2 PDB 1wa8 chain A domain 1 Region: 20 - 96 Aligned: 77 Modelled: 77 Confidence: 97.5% Identity: 18% Fold: Ferritin-like Superfamily: EsxAB dimer-like Family: ESAT-6 like Phyre2 PDB 4lws chain A Region: 20 - 98 Aligned: 79 Modelled: 76 Confidence: 97.3% Identity: 14% PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: esxa : esxb (semet) hetero-dimer from thermomonospora curvata Phyre2 PDB 4lws chain B Region: 20 - 95 Aligned: 76 Modelled: 76 Confidence: 97.3% Identity: 12% PDB header:unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: esxa : esxb (semet) hetero-dimer from thermomonospora curvata Phyre2 PDB 1wa8 chain B domain 1 Region: 21 - 98 Aligned: 78 Modelled: 78 Confidence: 97.1% Identity: 18% Fold: Ferritin-like Superfamily: EsxAB dimer-like Family: ESAT-6 like Phyre2 PDB 4i0x chain A Region: 21 - 95 Aligned: 75 Modelled: 75 Confidence: 96.4% Identity: 20% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:esat-6-like protein mab_3112; PDBTitle: crystal structure of the mycobacterum abscessus esxef (mab_3112-2 mab_3113) complex Phyre2 PDB 2kg7 chain B Region: 20 - 96 Aligned: 77 Modelled: 77 Confidence: 95.4% Identity: 8% PDB header:unknown function Chain: B: PDB Molecule:esat-6-like protein esxh; PDBTitle: structure and features of the complex formed by the tuberculosis2 virulence factors rv0287 and rv0288 Phyre2 PDB 4i0x chain J Region: 21 - 91 Aligned: 70 Modelled: 71 Confidence: 76.9% Identity: 13% PDB header:structural genomics, unknown function Chain: J: PDB Molecule:esat-6-like protein mab_3113; PDBTitle: crystal structure of the mycobacterum abscessus esxef (mab_3112-2 mab_3113) complex Phyre2 PDB 2ix0 chain A domain 4 Region: 2 - 19 Aligned: 18 Modelled: 18 Confidence: 19.4% Identity: 22% Fold: OB-fold Superfamily: Nucleic acid-binding proteins Family: RNB domain-like Phyre2 PDB 2vnu chain D domain 4 Region: 2 - 19 Aligned: 18 Modelled: 18 Confidence: 14.9% Identity: 11% Fold: OB-fold Superfamily: Nucleic acid-binding proteins Family: RNB domain-like Phyre2 PDB 1xyr chain 6 Region: 161 - 176 Aligned: 16 Modelled: 16 Confidence: 14.8% Identity: 31% PDB header:virus Chain: 6: PDB Molecule:genome polyprotein, coat protein vp3; PDB Fragment:residues 620-630 PDBTitle: poliovirus 135s cell entry intermediate Phyre2 PDB 2r7d chain A domain 2 Region: 2 - 19 Aligned: 17 Modelled: 18 Confidence: 14.7% Identity: 18% Fold: OB-fold Superfamily: Nucleic acid-binding proteins Family: RNB domain-like Phyre2 1 d2g38b1 2 c2g38B_ 3 c5xfsB_ 4 c4xy3A_ 5 c4wj2A_ 6 c2vs0B_ 7 c3gvmA_ 8 c3zbhC_ 9 c4iogD_ 10 d1wa8a1 11 c4lwsA_ 12 c4lwsB_ 13 d1wa8b1 14 c4i0xA_ 15 c2kg7B_ 16 c4i0xJ_ 17 d2ix0a4 18 d2vnud4 19 c1xyr6_ 20 d2r7da2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50