1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	N	N	R	P	I	R	L	L	T	S	G	R	A	G	L	G	A	G	A	L	I	T	A	V	V	L	L	I	A	L	G	A	V	W	T	P	V	A	F	A	D	G	C	P	D	A	E	V	T	F	A	R	G	T	G	E	P	P	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																								?	?	?	?	?	?	?	?	?	?	?	?																		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		I	G	R	V	G	Q	A	F	V	D	S	L	R	Q	Q	T	G	M	E	I	G	V	Y	P	V	N	Y	A	A	S	R	L	Q	L	H	G	G	D	G	A	N	D	A	I	S	H	I	K	S	M	A	S	S	C	P	N	T	K	L	V
Secondary structure
SS confidence
Disorder		?													?	?																		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	G	G	Y	S	Q	G	A	T	V	I	D	I	V	A	G	V	P	L	G	S	I	S	F	G	S	P	L	P	A	A	Y	A	D	N	V	A	A	V	A	V	F	G	N	P	S	N	R	A	G	G	S	L	S	S	L	S	P	L	F
Secondary structure
SS confidence
Disorder																				?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		G	S	K	A	I	D	L	C	N	P	T	D	P	I	C	H	V	G	P	G	N	E	F	S	G	H	I	D	G	Y	I	P	T	Y	T	T	Q	A	A	S	F	V	V	Q	R	L	R	A	G	S	V	P	H	L	P	G	S	V	P	Q
Secondary structure
SS confidence
Disorder																				?																													?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.
Sequence		L	P	G	S	V	L	Q	M	P	G	T	A	A	P	A	P	E	S	L	H	G	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 33%) Alpha helix ( 38%) Beta strand ( 13%) TM helix ( 6%) (View membrane topology prediction)

Rank Aligned region

PDB 4psd chain A Region: 1 - 227 Aligned: 209 Modelled: 227 Confidence: 100.0% Identity: 33% PDB header:hydrolase Chain: A: PDB Molecule:carbohydrate esterase family 5; PDBTitle: structure of trichoderma reesei cutinase native form. Phyre2 PDB 1qoz chain A Region: 44 - 227 Aligned: 179 Modelled: 184 Confidence: 100.0% Identity: 30% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Cutinase-like Phyre2 PDB 1cex chain A Region: 39 - 228 Aligned: 176 Modelled: 179 Confidence: 100.0% Identity: 23% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Cutinase-like Phyre2 PDB 1g66 chain A Region: 43 - 226 Aligned: 179 Modelled: 184 Confidence: 100.0% Identity: 29% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Cutinase-like Phyre2 PDB 5x88 chain A Region: 40 - 227 Aligned: 173 Modelled: 186 Confidence: 100.0% Identity: 28% PDB header:hydrolase Chain: A: PDB Molecule:cutinase; PDBTitle: a crystal structure of cutinases from malbranchea cinnamomea Phyre2 PDB 2czq chain B Region: 39 - 230 Aligned: 182 Modelled: 192 Confidence: 100.0% Identity: 27% PDB header:hydrolase Chain: B: PDB Molecule:cutinase-like protein; PDBTitle: a novel cutinase-like protein from cryptococcus sp. Phyre2 PDB 3dd5 chain F Region: 39 - 226 Aligned: 174 Modelled: 188 Confidence: 100.0% Identity: 26% PDB header:hydrolase Chain: F: PDB Molecule:cutinase; PDBTitle: glomerella cingulata e600-cutinase complex Phyre2 PDB 4oyl chain C Region: 39 - 227 Aligned: 172 Modelled: 189 Confidence: 100.0% Identity: 29% PDB header:hydrolase Chain: C: PDB Molecule:cutinase; PDBTitle: humicola insolens cutinase in complex with mono-ethylphosphate Phyre2 PDB 3gbs chain A Region: 33 - 226 Aligned: 179 Modelled: 190 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: A: PDB Molecule:cutinase 1; PDBTitle: crystal structure of aspergillus oryzae cutinase Phyre2 PDB 3aja chain A Region: 42 - 224 Aligned: 177 Modelled: 176 Confidence: 100.0% Identity: 25% PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of msmeg_6394 Phyre2 PDB 3hc7 chain A Region: 45 - 196 Aligned: 147 Modelled: 149 Confidence: 99.9% Identity: 24% PDB header:cell adhesion Chain: A: PDB Molecule:gene 12 protein; PDBTitle: crystal structure of lysin b from mycobacteriophage d29 Phyre2 PDB 3g7n chain A Region: 45 - 210 Aligned: 141 Modelled: 150 Confidence: 98.4% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:lipase; PDBTitle: crystal structure of a triacylglycerol lipase from penicillium2 expansum at 1.3 Phyre2 PDB 1uwc chain A Region: 45 - 210 Aligned: 144 Modelled: 159 Confidence: 97.9% Identity: 18% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Fungal lipases Phyre2 PDB 3ngm chain B Region: 101 - 210 Aligned: 98 Modelled: 109 Confidence: 97.7% Identity: 24% PDB header:hydrolase Chain: B: PDB Molecule:extracellular lipase; PDBTitle: crystal structure of lipase from gibberella zeae Phyre2 PDB 3tgl chain A Region: 92 - 210 Aligned: 112 Modelled: 118 Confidence: 97.6% Identity: 17% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Fungal lipases Phyre2 PDB 1tia chain A Region: 101 - 210 Aligned: 99 Modelled: 110 Confidence: 97.6% Identity: 20% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Fungal lipases Phyre2 PDB 6qpp chain A Region: 45 - 194 Aligned: 127 Modelled: 140 Confidence: 97.5% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:lipase; PDBTitle: rhizomucor miehei lipase propeptide complex, native Phyre2 PDB 5xk2 chain A Region: 101 - 210 Aligned: 98 Modelled: 110 Confidence: 97.3% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:diacylglycerol lipase; PDBTitle: crystal structure of mono- and diacylglycerol lipase from aspergillus2 oryzae Phyre2 PDB 1mo2 chain A Region: 24 - 165 Aligned: 131 Modelled: 131 Confidence: 97.3% Identity: 16% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Thioesterase domain of polypeptide, polyketide and fatty acid synthases Phyre2 PDB 1mo2 chain A Region: 24 - 165 Aligned: 131 Modelled: 131 Confidence: 97.3% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:erythronolide synthase, modules 5 and 6; PDBTitle: thioesterase domain from 6-deoxyerythronolide synthase (debs te), ph2 8.5 Phyre2 1 c4psdA_ 2 d1qoza_ 3 d1cexa_ 4 d1g66a_ 5 c5x88A_ 6 c2czqB_ 7 c3dd5F_ 8 c4oylC_ 9 c3gbsA_ 10 c3ajaA_ 11 c3hc7A_ 12 c3g7nA_ 13 d1uwca_ 14 c3ngmB_ 15 d3tgla_ 16 d1tiaa_ 17 c6qppA_ 18 c5xk2A_ 19 d1mo2a_ 20 c1mo2A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186