1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	I	P	R	P	Q	P	H	S	G	R	W	R	A	G	A	A	R	R	L	T	S	L	V	A	A	A	F	A	A	A	T	L	L	L	T	P	A	L	A	P	P	A	S	A	G	C	P	D	A	E	V	V	F	A	R	G	T	G	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	P	G	L	G	R	V	G	Q	A	F	V	S	S	L	R	Q	Q	T	N	K	S	I	G	T	Y	G	V	N	Y	P	A	N	G	D	F	L	A	A	A	D	G	A	N	D	A	S	D	H	I	Q	Q	M	A	S	A	C	R	A	T
Secondary structure
SS confidence
Disorder			?	?	?	?		?	?									?	?																				?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	L	V	L	G	G	Y	S	Q	G	A	A	V	I	D	I	V	T	A	A	P	L	P	G	L	G	F	T	Q	P	L	P	P	A	A	D	D	H	I	A	A	I	A	L	F	G	N	P	S	G	R	A	G	G	L	M	S	A	L	T
Secondary structure
SS confidence
Disorder																							?	?	?	?	?	?	?	?	?	?	?	?	?	?	?														?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.
Sequence		P	Q	F	G	S	K	T	I	N	L	C	N	N	G	D	P	I	C	S	D	G	N	R	W	R	A	H	L	G	Y	V	P	G	M	T	N	Q	A	A	R	F	V	A	S	R	I
Secondary structure
SS confidence
Disorder			?																																											?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 31%) Alpha helix ( 37%) Beta strand ( 15%) TM helix ( 7%) (View membrane topology prediction)

Rank Aligned region

PDB 1qoz chain A Region: 47 - 226 Aligned: 178 Modelled: 180 Confidence: 100.0% Identity: 31% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Cutinase-like Phyre2 PDB 1g66 chain A Region: 46 - 226 Aligned: 179 Modelled: 181 Confidence: 100.0% Identity: 31% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Cutinase-like Phyre2 PDB 4psd chain A Region: 15 - 226 Aligned: 196 Modelled: 212 Confidence: 100.0% Identity: 32% PDB header:hydrolase Chain: A: PDB Molecule:carbohydrate esterase family 5; PDBTitle: structure of trichoderma reesei cutinase native form. Phyre2 PDB 1cex chain A Region: 42 - 226 Aligned: 173 Modelled: 185 Confidence: 100.0% Identity: 29% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Cutinase-like Phyre2 PDB 3dd5 chain F Region: 42 - 226 Aligned: 173 Modelled: 175 Confidence: 100.0% Identity: 27% PDB header:hydrolase Chain: F: PDB Molecule:cutinase; PDBTitle: glomerella cingulata e600-cutinase complex Phyre2 PDB 5x88 chain A Region: 44 - 226 Aligned: 170 Modelled: 181 Confidence: 100.0% Identity: 28% PDB header:hydrolase Chain: A: PDB Molecule:cutinase; PDBTitle: a crystal structure of cutinases from malbranchea cinnamomea Phyre2 PDB 2czq chain B Region: 42 - 226 Aligned: 175 Modelled: 185 Confidence: 100.0% Identity: 27% PDB header:hydrolase Chain: B: PDB Molecule:cutinase-like protein; PDBTitle: a novel cutinase-like protein from cryptococcus sp. Phyre2 PDB 3gbs chain A Region: 44 - 226 Aligned: 170 Modelled: 173 Confidence: 100.0% Identity: 26% PDB header:hydrolase Chain: A: PDB Molecule:cutinase 1; PDBTitle: crystal structure of aspergillus oryzae cutinase Phyre2 PDB 4oyl chain C Region: 34 - 226 Aligned: 179 Modelled: 193 Confidence: 100.0% Identity: 29% PDB header:hydrolase Chain: C: PDB Molecule:cutinase; PDBTitle: humicola insolens cutinase in complex with mono-ethylphosphate Phyre2 PDB 3aja chain A Region: 45 - 212 Aligned: 162 Modelled: 168 Confidence: 100.0% Identity: 26% PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of msmeg_6394 Phyre2 PDB 3hc7 chain A Region: 51 - 203 Aligned: 147 Modelled: 150 Confidence: 100.0% Identity: 24% PDB header:cell adhesion Chain: A: PDB Molecule:gene 12 protein; PDBTitle: crystal structure of lysin b from mycobacteriophage d29 Phyre2 PDB 3g7n chain A Region: 48 - 211 Aligned: 139 Modelled: 149 Confidence: 98.3% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:lipase; PDBTitle: crystal structure of a triacylglycerol lipase from penicillium2 expansum at 1.3 Phyre2 PDB 3ngm chain B Region: 48 - 215 Aligned: 141 Modelled: 168 Confidence: 98.2% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:extracellular lipase; PDBTitle: crystal structure of lipase from gibberella zeae Phyre2 PDB 1uwc chain A Region: 48 - 211 Aligned: 139 Modelled: 164 Confidence: 97.9% Identity: 22% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Fungal lipases Phyre2 PDB 5xk2 chain A Region: 48 - 215 Aligned: 141 Modelled: 153 Confidence: 97.8% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:diacylglycerol lipase; PDBTitle: crystal structure of mono- and diacylglycerol lipase from aspergillus2 oryzae Phyre2 PDB 3tgl chain A Region: 104 - 211 Aligned: 101 Modelled: 107 Confidence: 97.7% Identity: 17% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Fungal lipases Phyre2 PDB 6qpp chain A Region: 48 - 197 Aligned: 127 Modelled: 140 Confidence: 97.6% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:lipase; PDBTitle: rhizomucor miehei lipase propeptide complex, native Phyre2 PDB 1tib chain A Region: 48 - 197 Aligned: 123 Modelled: 150 Confidence: 97.5% Identity: 18% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Fungal lipases Phyre2 PDB 1tca chain A Region: 52 - 170 Aligned: 103 Modelled: 119 Confidence: 97.5% Identity: 12% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Fungal lipases Phyre2 PDB 3icv chain A Region: 52 - 170 Aligned: 103 Modelled: 119 Confidence: 97.4% Identity: 12% PDB header:hydrolase Chain: A: PDB Molecule:lipase b; PDBTitle: structural consequences of a circular permutation on lipase b from2 candida antartica Phyre2 1 d1qoza_ 2 d1g66a_ 3 c4psdA_ 4 d1cexa_ 5 c3dd5F_ 6 c5x88A_ 7 c2czqB_ 8 c3gbsA_ 9 c4oylC_ 10 c3ajaA_ 11 c3hc7A_ 12 c3g7nA_ 13 c3ngmB_ 14 d1uwca_ 15 c5xk2A_ 16 d3tgla_ 17 c6qppA_ 18 d1tiba_ 19 d1tcaa_ 20 c3icvA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203