1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	P	G	V	I	T	N	S	E	S	P	T	A	A	D	H	D	R	I	T	A	T	R	E	T	L	E	D	Y	T	L	R	L	A	P	R	S	Y	R	R	W	P	P	A	V	V	G	I	S	A	L	G	G	I	A	Y	L	A	D	F
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?							?																							?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110
Sequence		A	I	G	A	N	V	G	I	T	W	G	T	A	N	A	L	C	G	I	A	I	F	A	L	V	V	F	V	T	G	L	P	L	A	Y	Y	A	A	R	Y	N	I	D	L	D	L	I	Y	P	R
Secondary structure
SS confidence
Disorder																																														?		?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 19%) Alpha helix ( 80%) Beta strand ( 0%) TM helix ( 44%) (View membrane topology prediction)

Rank Aligned region

PDB 2jln chain A Region: 23 - 103 Aligned: 81 Modelled: 81 Confidence: 98.3% Identity: 12% PDB header:membrane protein Chain: A: PDB Molecule:mhp1; PDBTitle: structure of mhp1, a nucleobase-cation-symport-1 family2 transporter Phyre2 PDB 5nva chain A Region: 22 - 104 Aligned: 77 Modelled: 83 Confidence: 71.3% Identity: 14% PDB header:membrane protein Chain: A: PDB Molecule:putative sodium:solute symporter; PDBTitle: substrate-bound outward-open state of a na+-coupled sialic acid2 symporter reveals a novel na+-site Phyre2 PDB 5edl chain A Region: 31 - 102 Aligned: 72 Modelled: 72 Confidence: 61.3% Identity: 10% PDB header:transport protein Chain: A: PDB Molecule:putative hmp/thiamine permease protein ykoe; PDBTitle: crystal structure of an s-component of ecf transporter Phyre2 PDB 5oqt chain A Region: 23 - 100 Aligned: 78 Modelled: 78 Confidence: 45.5% Identity: 10% PDB header:transport protein Chain: A: PDB Molecule:amino acid transporter; PDBTitle: crystal structure of a bacterial cationic amino acid transporter (cat)2 homologue Phyre2 PDB 4b03 chain A Region: 43 - 88 Aligned: 46 Modelled: 46 Confidence: 33.0% Identity: 13% PDB header:virus Chain: A: PDB Molecule:dengue virus 1 e protein; PDBTitle: 6a electron cryomicroscopy structure of immature dengue virus serotype2 1 Phyre2 PDB 3gia chain A Region: 39 - 100 Aligned: 61 Modelled: 62 Confidence: 25.4% Identity: 10% PDB header:transport protein Chain: A: PDB Molecule:uncharacterized protein mj0609; PDBTitle: crystal structure of apct transporter Phyre2 PDB 5ire chain A Region: 43 - 88 Aligned: 46 Modelled: 46 Confidence: 20.0% Identity: 22% PDB header:virus Chain: A: PDB Molecule:e protein; PDBTitle: the cryo-em structure of zika virus Phyre2 PDB 6f2w chain A Region: 39 - 100 Aligned: 62 Modelled: 62 Confidence: 17.7% Identity: 15% PDB header:transport protein Chain: A: PDB Molecule:putative amino acid/polyamine transport protein; PDBTitle: bacterial asc transporter crystal structure in open to in conformation Phyre2 PDB 4ymu chain C Region: 71 - 101 Aligned: 31 Modelled: 31 Confidence: 15.4% Identity: 16% PDB header:protein binding/transport protein Chain: C: PDB Molecule:abc-type amino acid transport system, permease component; PDBTitle: crystal structure of an amino acid abc transporter complex with2 arginines and atps Phyre2 PDB 1pw4 chain A Region: 33 - 101 Aligned: 69 Modelled: 69 Confidence: 14.9% Identity: 12% Fold: MFS general substrate transporter Superfamily: MFS general substrate transporter Family: Glycerol-3-phosphate transporter Phyre2 PDB 4k1c chain B Region: 13 - 101 Aligned: 89 Modelled: 89 Confidence: 13.7% Identity: 12% PDB header:membrane protein/metal transport Chain: B: PDB Molecule:vacuolar calcium ion transporter; PDBTitle: vcx1 calcium/proton exchanger Phyre2 PDB 5b7i chain C Region: 12 - 55 Aligned: 44 Modelled: 44 Confidence: 13.0% Identity: 16% PDB header:hydrolase/unknown function Chain: C: PDB Molecule:uncharacterized protein acrf3; PDBTitle: cas3-acrf3 complex Phyre2 PDB 4oua chain B Region: 1 - 49 Aligned: 48 Modelled: 49 Confidence: 12.2% Identity: 10% PDB header:oxidoreductase Chain: B: PDB Molecule:latent form of ppo4 tyrosinase; PDBTitle: coexistent single-crystal structure of latent and active mushroom2 tyrosinase (abppo4) mediated by a hexatungstotellurate(vi) Phyre2 PDB 3dh4 chain A Region: 39 - 104 Aligned: 65 Modelled: 66 Confidence: 12.0% Identity: 15% PDB header:transport protein Chain: A: PDB Molecule:sodium/glucose cotransporter; PDBTitle: crystal structure of sodium/sugar symporter with bound galactose from2 vibrio parahaemolyticus Phyre2 PDB 3lrc chain C Region: 38 - 100 Aligned: 61 Modelled: 63 Confidence: 11.6% Identity: 18% PDB header:transport protein Chain: C: PDB Molecule:arginine/agmatine antiporter; PDBTitle: structure of e. coli adic (p1) Phyre2 PDB 1p58 chain C Region: 42 - 89 Aligned: 48 Modelled: 48 Confidence: 10.1% Identity: 13% PDB header:virus Chain: C: PDB Molecule:major envelope protein e; PDBTitle: complex organization of dengue virus membrane proteins as revealed by2 9.5 angstrom cryo-em reconstruction Phyre2 PDB 4qid chain B Region: 34 - 104 Aligned: 71 Modelled: 71 Confidence: 10.0% Identity: 11% PDB header:membrane protein Chain: B: PDB Molecule:bacteriorhodopsin-i; PDBTitle: crystal structure of haloquadratum walsbyi bacteriorhodopsin Phyre2 PDB 3f4y chain F Region: 19 - 32 Aligned: 14 Modelled: 14 Confidence: 9.6% Identity: 21% PDB header:viral protein Chain: F: PDB Molecule:mutant peptide derived from hiv gp41 chr domain; PDBTitle: hiv gp41 six-helix bundle containing a mutant chr alpha-2 peptide sequence Phyre2 PDB 1e5x chain A Region: 89 - 110 Aligned: 22 Modelled: 22 Confidence: 9.4% Identity: 27% Fold: Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily: Tryptophan synthase beta subunit-like PLP-dependent enzymes Family: Tryptophan synthase beta subunit-like PLP-dependent enzymes Phyre2 PDB 3da1 chain A Region: 87 - 107 Aligned: 21 Modelled: 21 Confidence: 9.4% Identity: 29% PDB header:oxidoreductase Chain: A: PDB Molecule:glycerol-3-phosphate dehydrogenase; PDBTitle: x-ray structure of the glycerol-3-phosphate dehydrogenase2 from bacillus halodurans complexed with fad. northeast3 structural genomics consortium target bhr167. Phyre2 1 c2jlnA_ 2 c5nvaA_ 3 c5edlA_ 4 c5oqtA_ 5 c4b03A_ 6 c3giaA_ 7 c5ireA_ 8 c6f2wA_ 9 c4ymuC_ 10 d1pw4a_ 11 c4k1cB_ 12 c5b7iC_ 13 c4ouaB_ 14 c3dh4A_ 15 c3lrcC_ 16 c1p58C_ 17 c4qidB_ 18 c3f4yF_ 19 d1e5xa_ 20 c3da1A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60