1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	R	Y	T	G	P	V	T	R	K	S	R	R	L	R	T	D	L	V	G	G	D	Q	A	F	E	K	R	P	Y	P	P	G	Q	H	G	R	A	R	I	K	E	S	E	Y	L	L	Q	L	Q	E	K	Q	K	A	R	F	T	Y
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?		?					?				?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	V	M	E	K	Q	F	R	R	Y	Y	E	E	A	V	R	Q	P	G	K	T	G	E	E	L	L	K	I	L	E	S	R	L	D	N	V	I	Y	R	A	G	L	A	R	T	R	R	M	A	R	Q	L	V	S	H	G	H	F	N	V
Secondary structure
SS confidence
Disorder																?	?	?	?	?	?	?																						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		N	G	V	H	V	N	V	P	S	Y	R	V	S	Q	Y	D	I	V	D	V	R	D	K	S	L	N	T	V	P	F	Q	I	A	R	E	T	A	G	E	R	P	I	P	S	W	L	Q	V	V	G	E	R	Q	R	V	L	I	H	Q	L
Secondary structure
SS confidence
Disorder																										?	?	?								?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.
Sequence		P	E	R	A	Q	I	D	V	P	L	T	E	Q	L	I	V	E	Y	Y	S	K
Secondary structure
SS confidence
Disorder																					?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 27%) Alpha helix ( 37%) Beta strand ( 17%)

Rank Aligned region

PDB 5o5j chain D Region: 2 - 201 Aligned: 200 Modelled: 200 Confidence: 100.0% Identity: 89% PDB header:ribosome Chain: D: PDB Molecule:30s ribosomal protein s4; PDBTitle: structure of the 30s small ribosomal subunit from mycobacterium2 smegmatis Phyre2 PDB 2uub chain D domain 1 Region: 2 - 201 Aligned: 200 Modelled: 200 Confidence: 100.0% Identity: 47% Fold: Alpha-L RNA-binding motif Superfamily: Alpha-L RNA-binding motif Family: Ribosomal protein S4 Phyre2 PDB 2gy9 chain D domain 1 Region: 3 - 201 Aligned: 199 Modelled: 199 Confidence: 100.0% Identity: 48% Fold: Alpha-L RNA-binding motif Superfamily: Alpha-L RNA-binding motif Family: Ribosomal protein S4 Phyre2 PDB 3bbn chain D Region: 1 - 201 Aligned: 199 Modelled: 201 Confidence: 100.0% Identity: 36% PDB header:ribosome Chain: D: PDB Molecule:ribosomal protein s4; PDBTitle: homology model for the spinach chloroplast 30s subunit fitted to 9.4a2 cryo-em map of the 70s chlororibosome. Phyre2 PDB 1c06 chain A Region: 42 - 201 Aligned: 158 Modelled: 160 Confidence: 100.0% Identity: 53% Fold: Alpha-L RNA-binding motif Superfamily: Alpha-L RNA-binding motif Family: Ribosomal protein S4 Phyre2 PDB 3j20 chain D Region: 28 - 144 Aligned: 117 Modelled: 117 Confidence: 99.9% Identity: 37% PDB header:ribosome Chain: D: PDB Molecule:30s ribosomal protein s4p; PDBTitle: promiscuous behavior of proteins in archaeal ribosomes revealed by2 cryo-em: implications for evolution of eukaryotic ribosomes (30s3 ribosomal subunit) Phyre2 PDB 5wxm chain A Region: 41 - 142 Aligned: 102 Modelled: 102 Confidence: 99.8% Identity: 23% PDB header:ribosomal protein Chain: A: PDB Molecule:u3 small nucleolar ribonucleoprotein protein imp3; PDBTitle: crystal structure of the imp3 and mpp10 complex Phyre2 PDB 2xzm chain D Region: 47 - 145 Aligned: 99 Modelled: 99 Confidence: 99.8% Identity: 32% PDB header:ribosome Chain: D: PDB Molecule:ribosomal protein s4 containing protein; PDBTitle: crystal structure of the eukaryotic 40s ribosomal2 subunit in complex with initiation factor 1. this file3 contains the 40s subunit and initiation factor for4 molecule 1 Phyre2 PDB 1s1h chain D Region: 40 - 145 Aligned: 106 Modelled: 106 Confidence: 99.7% Identity: 25% PDB header:ribosome Chain: D: PDB Molecule:40s ribosomal protein s9-a; PDBTitle: structure of the ribosomal 80s-eef2-sordarin complex from yeast2 obtained by docking atomic models for rna and protein components into3 a 11.7 a cryo-em map. this file, 1s1h, contains 40s subunit. the 60s4 ribosomal subunit is in file 1s1i. Phyre2 PDB 5jpq chain B Region: 42 - 145 Aligned: 99 Modelled: 104 Confidence: 99.7% Identity: 19% PDB header:ribosome Chain: B: PDB Molecule:wd40 domain proteins; PDBTitle: cryo-em structure of the 90s pre-ribosome Phyre2 PDB 5xyi chain J Region: 47 - 145 Aligned: 99 Modelled: 99 Confidence: 99.7% Identity: 21% PDB header:ribosome Chain: J: PDB Molecule:uncharacterized protein; PDBTitle: small subunit of trichomonas vaginalis ribosome Phyre2 PDB 6nd4 chain Z Region: 87 - 144 Aligned: 58 Modelled: 58 Confidence: 99.7% Identity: 31% PDB header:ribosome Chain: Z: PDB Molecule:imp3; PDBTitle: conformational switches control early maturation of the eukaryotic2 small ribosomal subunit Phyre2 PDB 3zey chain 6 Region: 42 - 144 Aligned: 96 Modelled: 103 Confidence: 99.7% Identity: 26% PDB header:ribosome Chain: 6: PDB Molecule:40s ribosomal protein s9, putative; PDBTitle: high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome Phyre2 PDB 3izb chain C Region: 33 - 144 Aligned: 111 Modelled: 112 Confidence: 99.6% Identity: 28% PDB header:ribosome Chain: C: PDB Molecule:40s ribosomal protein rps9 (s4p); PDBTitle: localization of the small subunit ribosomal proteins into a 6.1 a2 cryo-em map of saccharomyces cerevisiae translating 80s ribosome Phyre2 PDB 3iz6 chain C Region: 88 - 144 Aligned: 57 Modelled: 57 Confidence: 99.5% Identity: 32% PDB header:ribosome Chain: C: PDB Molecule:40s ribosomal protein s9 (s4p); PDBTitle: localization of the small subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome Phyre2 PDB 2cqj chain A Region: 91 - 145 Aligned: 55 Modelled: 55 Confidence: 99.5% Identity: 29% PDB header:rna binding protein Chain: A: PDB Molecule:u3 small nucleolar ribonucleoprotein protein PDBTitle: solution structure of the s4 domain of u3 small nucleolar2 ribonucleoprotein protein imp3 homolog Phyre2 PDB 5z81 chain A Region: 90 - 141 Aligned: 51 Modelled: 52 Confidence: 99.3% Identity: 33% PDB header:chaperone Chain: A: PDB Molecule:heat shock protein 15; PDBTitle: trimeric structure of vibrio cholerae heat shock protein 15 at 2.32 angstrom resolution Phyre2 PDB 1dm9 chain A Region: 90 - 141 Aligned: 51 Modelled: 52 Confidence: 99.3% Identity: 31% PDB header:structural genomics Chain: A: PDB Molecule:hypothetical 15.5 kd protein in mrca-pcka intergenic PDBTitle: heat shock protein 15 kd Phyre2 PDB 1dm9 chain A Region: 90 - 141 Aligned: 51 Modelled: 52 Confidence: 99.3% Identity: 31% Fold: Alpha-L RNA-binding motif Superfamily: Alpha-L RNA-binding motif Family: Heat shock protein 15 kD Phyre2 PDB 1p9k chain A Region: 74 - 145 Aligned: 72 Modelled: 72 Confidence: 99.3% Identity: 15% Fold: Alpha-L RNA-binding motif Superfamily: Alpha-L RNA-binding motif Family: YbcJ-like Phyre2 1 c5o5jD_ 2 d2uubd1 3 d2gy9d1 4 c3bbnD_ 5 d1c06a_ 6 c3j20D_ 7 c5wxmA_ 8 c2xzmD_ 9 c1s1hD_ 10 c5jpqb_ 11 c5xyiJ_ 12 c6nd4Z_ 13 c3zey6_ 14 c3izbC_ 15 c3iz6C_ 16 c2cqjA_ 17 c5z81A_ 18 c1dm9A_ 19 d1dm9a_ 20 d1p9ka_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154