1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	G	G	G	S	R	R	T	S	V	R	V	A	A	A	L	L	A	G	L	M	V	G	S	A	V	L	T	Y	L	S	Y	T	A	A	F	T	S	T	D	T	V	T	V	S	S	P	R	A	G	L	V	M	E	K	G	A	K	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																											?	?	?	?	?												?	?	?	?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		K	Y	R	G	I	Q	V	G	K	V	T	D	I	S	Y	S	G	N	Q	A	R	L	K	L	A	I	D	S	G	E	M	G	F	I	P	S	N	A	T	V	R	I	A	G	N	T	I	F	G	A	K	S	V	E	F	I	P	P	K	T
Secondary structure
SS confidence
Disorder																	?													?	?	?	?	?	?											?	?	?	?	?								?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		P	S	P	K	P	L	S	P	N	A	H	V	A	A	S	Q	V	Q	L	E	V	N	T	L	F	Q	S	L	I	D	L	L	H	K	I	D	P	L	E	T	N	A	T	L	S	A	L	S	E	G	L	R	G	H	G	D	D	L	G	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?		?		?	?	?	?	?	?	?	?	?	?																?																	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	L	S	G	L	N	T	L	T	R	Q	A	N	P	K	L	P	A	L	Q	E	D	F	R	K	A	A	V	V	A	N	V	Y	A	D	A	A	G	D	L	N	T	V	F	D	N	L	P	T	I	N	K	T	I	V	D	Q	K	D	N
Secondary structure
SS confidence
Disorder																																					?																					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	N	D	T	L	L	A	T	I	G	L	S	N	N	A	Y	E	T	L	A	P	A	E	Q	N	F	I	D	A	I	N	R	L	R	A	P	L	K	V	T	S	D	Y	S	P	V	F	G	C	L	F	K	G	I	A	R	G	V	K	E
Secondary structure
SS confidence
Disorder																																												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		F	A	P	L	I	G	V	R	K	A	G	L	F	T	S	S	S	F	V	L	G	A	P	S	Y	T	Y	P	E	S	L	P	I	V	N	A	S	G	G	P	N	C	R	G	L	P	D	I	P	T	K	Q	T	G	G	S	F	Y	R	A
Secondary structure
SS confidence
Disorder					?																																													?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400
Sequence		P	F	L	V	T	D	N	A	L	I	P	Y	Q	P	F	T	E	L	Q	V	D	A	P	S	T	L	Q	F	L	F	N	G	A	F	A	E	R	D	D	F
Secondary structure
SS confidence
Disorder		?		?	?	?	?	?	?	?	?	?	?			?	?	?	?	?	?	?	?												?		?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 24%) Alpha helix ( 48%) Beta strand ( 13%) TM helix ( 5%) (View membrane topology prediction)

Rank Aligned region

PDB 6ic4 chain C Region: 13 - 147 Aligned: 132 Modelled: 135 Confidence: 99.8% Identity: 17% PDB header:protein transport Chain: C: PDB Molecule:toluene tolerance efflux transporter (abc superfamily, PDBTitle: cryo-em structure of the a. baumannii mla complex at 8.7 a resolution Phyre2 PDB 5uw8 chain C Region: 38 - 138 Aligned: 99 Modelled: 101 Confidence: 99.5% Identity: 17% PDB header:transport protein Chain: C: PDB Molecule:probable phospholipid abc transporter-binding protein mlad; PDBTitle: structure of e. coli mce protein mlad, core mce domain Phyre2 PDB 5uvn chain B Region: 37 - 156 Aligned: 108 Modelled: 120 Confidence: 99.2% Identity: 19% PDB header:transport protein Chain: B: PDB Molecule:paraquat-inducible protein b; PDBTitle: structure of e. coli mce protein pqib, periplasmic domain Phyre2 PDB 5uvn chain F Region: 37 - 156 Aligned: 108 Modelled: 120 Confidence: 99.2% Identity: 19% PDB header:transport protein Chain: F: PDB Molecule:paraquat-inducible protein b; PDBTitle: structure of e. coli mce protein pqib, periplasmic domain Phyre2 PDB 5uvn chain C Region: 37 - 156 Aligned: 108 Modelled: 120 Confidence: 99.2% Identity: 19% PDB header:transport protein Chain: C: PDB Molecule:paraquat-inducible protein b; PDBTitle: structure of e. coli mce protein pqib, periplasmic domain Phyre2 PDB 5uvn chain A Region: 37 - 156 Aligned: 108 Modelled: 120 Confidence: 99.2% Identity: 19% PDB header:transport protein Chain: A: PDB Molecule:paraquat-inducible protein b; PDBTitle: structure of e. coli mce protein pqib, periplasmic domain Phyre2 PDB 5uvn chain E Region: 37 - 156 Aligned: 108 Modelled: 120 Confidence: 99.2% Identity: 19% PDB header:transport protein Chain: E: PDB Molecule:paraquat-inducible protein b; PDBTitle: structure of e. coli mce protein pqib, periplasmic domain Phyre2 PDB 5uvn chain D Region: 37 - 156 Aligned: 108 Modelled: 120 Confidence: 99.2% Identity: 19% PDB header:transport protein Chain: D: PDB Molecule:paraquat-inducible protein b; PDBTitle: structure of e. coli mce protein pqib, periplasmic domain Phyre2 PDB 1qu7 chain A Region: 140 - 290 Aligned: 151 Modelled: 151 Confidence: 90.5% Identity: 7% PDB header:signaling protein Chain: A: PDB Molecule:methyl-accepting chemotaxis protein i; PDBTitle: four helical-bundle structure of the cytoplasmic domain of a serine2 chemotaxis receptor Phyre2 PDB 3g67 chain A Region: 141 - 304 Aligned: 162 Modelled: 164 Confidence: 88.3% Identity: 11% PDB header:signaling protein Chain: A: PDB Molecule:methyl-accepting chemotaxis protein; PDBTitle: crystal structure of a soluble chemoreceptor from thermotoga2 maritima Phyre2 PDB 6b7n chain C Region: 153 - 282 Aligned: 126 Modelled: 130 Confidence: 81.5% Identity: 11% PDB header:viral protein Chain: C: PDB Molecule:spike protein; PDBTitle: cryo-electron microscopy structure of porcine delta coronavirus spike2 protein in the pre-fusion state Phyre2 PDB 3lnr chain A Region: 145 - 261 Aligned: 111 Modelled: 117 Confidence: 81.1% Identity: 14% PDB header:signaling protein Chain: A: PDB Molecule:aerotaxis transducer aer2; PDBTitle: crystal structure of poly-hamp domains from the p. aeruginosa soluble2 receptor aer2 Phyre2 PDB 2j5u chain B Region: 63 - 107 Aligned: 43 Modelled: 45 Confidence: 68.8% Identity: 14% PDB header:cell shape regulation Chain: B: PDB Molecule:mrec protein; PDBTitle: mrec lysteria monocytogenes Phyre2 PDB 2ch7 chain A Region: 176 - 304 Aligned: 129 Modelled: 129 Confidence: 66.2% Identity: 9% PDB header:chemotaxis Chain: A: PDB Molecule:methyl-accepting chemotaxis protein; PDBTitle: crystal structure of the cytoplasmic domain of a bacterial2 chemoreceptor from thermotoga maritima Phyre2 PDB 5lp5 chain F Region: 63 - 88 Aligned: 26 Modelled: 26 Confidence: 63.0% Identity: 23% PDB header:hydrolase/antibiotic Chain: F: PDB Molecule:rod shape-determining protein (mrec); PDBTitle: complex between penicillin-binding protein (pbp2) and mrec from2 helicobacter pylori Phyre2 PDB 3cwg chain A Region: 141 - 273 Aligned: 133 Modelled: 133 Confidence: 58.8% Identity: 14% PDB header:transcription Chain: A: PDB Molecule:signal transducer and activator of transcription PDBTitle: unphosphorylated mouse stat3 core fragment Phyre2 PDB 2qf4 chain A Region: 53 - 132 Aligned: 74 Modelled: 80 Confidence: 57.8% Identity: 16% PDB header:structural protein Chain: A: PDB Molecule:cell shape determining protein mrec; PDBTitle: high resolution structure of the major periplasmic domain from the2 cell shape-determining filament mrec (orthorhombic form) Phyre2 PDB 5xbj chain A Region: 161 - 273 Aligned: 113 Modelled: 113 Confidence: 57.2% Identity: 14% PDB header:biosynthetic protein Chain: A: PDB Molecule:flagellar hook-associated protein flgk; PDBTitle: the structure of the flagellar hook junction protein hap1 (flgk) from2 campylobacter jejuni Phyre2 PDB 1st6 chain A domain 4 Region: 198 - 275 Aligned: 78 Modelled: 78 Confidence: 53.4% Identity: 12% Fold: Four-helical up-and-down bundle Superfamily: alpha-catenin/vinculin-like Family: alpha-catenin/vinculin Phyre2 PDB 6nb3 chain B Region: 140 - 236 Aligned: 91 Modelled: 97 Confidence: 50.5% Identity: 12% PDB header:virus Chain: B: PDB Molecule:spike glycoprotein; PDBTitle: mers-cov complex with human neutralizing lca60 antibody fab fragment2 (state 1) Phyre2 1 c6ic4C_ 2 c5uw8C_ 3 c5uvnB_ 4 c5uvnF_ 5 c5uvnC_ 6 c5uvnA_ 7 c5uvnE_ 8 c5uvnD_ 9 c1qu7A_ 10 c3g67A_ 11 c6b7nC_ 12 c3lnrA_ 13 c2j5uB_ 14 c2ch7A_ 15 c5lp5F_ 16 c3cwgA_ 17 c2qf4A_ 18 c5xbjA_ 19 d1st6a4 20 c6nb3B_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99