1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	G	P	T	L	S	R	F	F	T	A	L	R	A	R	R	I	V	G	V	R	G	S	D	G	R	V	H	V	P	P	V	E	Y	D	P	V	T	Y	E	P	L	S	E	M	V	P	V	S	S	V	G	T	V	A	S	W	T	W	Q
Secondary structure
SS confidence
Disorder		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	E	P	L	A	G	Q	P	L	D	R	P	F	A	W	A	L	I	K	L	D	G	A	D	T	L	L	M	H	A	V	D	V	G	T	A	G	P	S	A	I	H	T	G	A	R	V	H	A	H	W	A	D	Q	P	V	G	A	I	T
Secondary structure
SS confidence
Disorder					?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		D	I	A	C	F	A	L	G	E	T	A	E	P	V	A	A	H	K	T	E	D	A	R	D	P	V	T	M	I	V	T	P	I	Q	L	E	I	Q	H	T	A	S	H	E	E	S	A	Y	L	R	A	I	A	Q	G	K	L	V	G	A
Secondary structure
SS confidence
Disorder										?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		R	T	G	K	T	G	K	V	Y	F	P	P	H	G	A	D	P	A	T	G	K	P	T	S	E	F	V	E	L	P	D	K	G	T	V	T	T	F	A	I	V	N	I	P	F	L	G	Q	R	I	K	P	P	Y	V	A	A	Y	V	L
Secondary structure
SS confidence
Disorder																																															?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	D	G	A	D	I	P	F	L	H	L	V	S	D	V	D	A	H	Q	V	R	M	G	M	R	V	E	A	V	W	K	P	R	E	R	W	G	L	G	I	D	N	I	E	Y	F	R	P	T	G	E	P	D	A	N	Y	D	T	Y	K
Secondary structure
SS confidence
Disorder																																																										?			?
Disorder confidence
		.	.	.
Sequence		H	H	L
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 10%) Alpha helix ( 11%) Beta strand ( 39%)

Rank Aligned region

PDB 6ok1 chain B Region: 160 - 290 Aligned: 125 Modelled: 131 Confidence: 100.0% Identity: 22% PDB header:transport protein Chain: B: PDB Molecule:chsh2(duf35); PDBTitle: ltp2-chsh2(duf35) aldolase Phyre2 PDB 6et9 chain H Region: 165 - 289 Aligned: 123 Modelled: 125 Confidence: 100.0% Identity: 28% PDB header:transferase Chain: H: PDB Molecule:pfam duf35; PDBTitle: structure of the acetoacetyl-coa-thiolase/hmg-coa-synthase complex2 from methanothermococcus thermolithotrophicus at 2.75 a Phyre2 PDB 2gnr chain A domain 1 Region: 157 - 276 Aligned: 116 Modelled: 116 Confidence: 100.0% Identity: 16% Fold: OB-fold Superfamily: Nucleic acid-binding proteins Family: SSO2064-like Phyre2 PDB 5mg5 chain W Region: 156 - 291 Aligned: 134 Modelled: 136 Confidence: 100.0% Identity: 17% PDB header:transferase Chain: W: PDB Molecule:2,4-diacetylphloroglucinol biosynthesis protein; PDBTitle: a multi-component acyltransferase phlabc from pseudomonas protegens2 soaked with the monoacetylphloroglucinol (mapg) Phyre2 PDB 2lcq chain A Region: 181 - 202 Aligned: 22 Modelled: 22 Confidence: 93.4% Identity: 27% PDB header:metal binding protein Chain: A: PDB Molecule:putative toxin vapc6; PDBTitle: solution structure of the endonuclease nob1 from p.horikoshii Phyre2 PDB 2kdx chain A Region: 180 - 208 Aligned: 29 Modelled: 29 Confidence: 92.9% Identity: 10% PDB header:metal-binding protein Chain: A: PDB Molecule:hydrogenase/urease nickel incorporation protein PDBTitle: solution structure of hypa protein Phyre2 PDB 3a44 chain D Region: 181 - 205 Aligned: 25 Modelled: 25 Confidence: 92.8% Identity: 20% PDB header:metal binding protein Chain: D: PDB Molecule:hydrogenase nickel incorporation protein hypa; PDBTitle: crystal structure of hypa in the dimeric form Phyre2 PDB 6g5i chain Y Region: 173 - 210 Aligned: 38 Modelled: 38 Confidence: 91.8% Identity: 13% PDB header:ribosome Chain: Y: PDB Molecule:40s ribosomal protein s24; PDBTitle: cryo-em structure of a late human pre-40s ribosomal subunit - state r Phyre2 PDB 2fiy chain A domain 1 Region: 172 - 203 Aligned: 32 Modelled: 32 Confidence: 91.4% Identity: 9% Fold: FdhE-like Superfamily: FdhE-like Family: FdhE-like Phyre2 PDB 1dvb chain A Region: 166 - 210 Aligned: 45 Modelled: 45 Confidence: 91.3% Identity: 27% PDB header:electron transport Chain: A: PDB Molecule:rubrerythrin; PDBTitle: rubrerythrin Phyre2 PDB 4u3e chain A Region: 179 - 207 Aligned: 26 Modelled: 29 Confidence: 89.9% Identity: 15% PDB header:oxidoreductase Chain: A: PDB Molecule:ribonucleoside triphosphate reductase; PDBTitle: anaerobic ribonucleotide reductase Phyre2 PDB 5ijl chain A Region: 180 - 203 Aligned: 22 Modelled: 24 Confidence: 89.1% Identity: 32% PDB header:transferase Chain: A: PDB Molecule:dna polymerase ii large subunit; PDBTitle: d-family dna polymerase - dp2 subunit (catalytic subunit) Phyre2 PDB 1lko chain A domain 2 Region: 181 - 210 Aligned: 29 Modelled: 30 Confidence: 87.7% Identity: 31% Fold: Rubredoxin-like Superfamily: Rubredoxin-like Family: Rubredoxin Phyre2 PDB 2con chain A domain 1 Region: 176 - 210 Aligned: 35 Modelled: 35 Confidence: 87.3% Identity: 14% Fold: Rubredoxin-like Superfamily: NOB1 zinc finger-like Family: NOB1 zinc finger-like Phyre2 PDB 2hr5 chain B Region: 166 - 209 Aligned: 43 Modelled: 44 Confidence: 86.8% Identity: 16% PDB header:metal binding protein Chain: B: PDB Molecule:rubrerythrin; PDBTitle: pf1283- rubrerythrin from pyrococcus furiosus iron bound form Phyre2 PDB 2ey4 chain E domain 1 Region: 179 - 203 Aligned: 23 Modelled: 25 Confidence: 86.7% Identity: 22% Fold: Rubredoxin-like Superfamily: Nop10-like SnoRNP Family: Nucleolar RNA-binding protein Nop10-like Phyre2 PDB 1hk8 chain A Region: 179 - 211 Aligned: 33 Modelled: 33 Confidence: 86.1% Identity: 6% Fold: PFL-like glycyl radical enzymes Superfamily: PFL-like glycyl radical enzymes Family: Class III anaerobic ribonucleotide reductase NRDD subunit Phyre2 PDB 1hk8 chain A Region: 179 - 211 Aligned: 33 Modelled: 33 Confidence: 86.1% Identity: 6% PDB header:oxidoreductase Chain: A: PDB Molecule:anaerobic ribonucleotide-triphosphate reductase; PDBTitle: structural basis for allosteric substrate specificity regulation in2 class iii ribonucleotide reductases: nrdd in complex with dgtp Phyre2 PDB 2apo chain B domain 1 Region: 179 - 203 Aligned: 23 Modelled: 24 Confidence: 85.8% Identity: 22% Fold: Rubredoxin-like Superfamily: Nop10-like SnoRNP Family: Nucleolar RNA-binding protein Nop10-like Phyre2 PDB 6rxn chain A Region: 181 - 209 Aligned: 29 Modelled: 29 Confidence: 85.5% Identity: 21% Fold: Rubredoxin-like Superfamily: Rubredoxin-like Family: Rubredoxin Phyre2 1 c6ok1B_ 2 c6et9H_ 3 d2gnra1 4 c5mg5W_ 5 c2lcqA_ 6 c2kdxA_ 7 c3a44D_ 8 c6g5iy_ 9 d2fiya1 10 c1dvbA_ 11 c4u3eA_ 12 c5ijlA_ 13 d1lkoa2 14 d2cona1 15 c2hr5B_ 16 d2ey4e1 17 d1hk8a_ 18 c1hk8A_ 19 d2apob1 20 d6rxna_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176