1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	P	D	K	R	T	A	L	D	D	A	V	A	Q	L	R	S	G	M	T	I	G	I	A	G	W	G	S	R	R	K	P	M	A	F	V	R	A	I	L	R	S	D	V	T	D	L	T	V	V	T	Y	G	G	P	D	L	G	L	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		C	S	A	G	K	V	K	R	V	Y	Y	G	F	V	S	L	D	S	P	P	F	Y	D	P	W	F	A	H	A	R	T	S	G	A	I	E	A	R	E	M	D	E	G	M	L	R	C	G	L	Q	A	A	A	Q	R	L	P	F	L	P
Secondary structure
SS confidence
Disorder																	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		I	R	A	G	L	G	S	S	V	P	Q	F	W	A	G	E	L	Q	T	V	T	S	P	Y	P	A	P	G	G	G	Y	E	T	L	I	A	M	P	A	L	R	L	D	A	A	F	A	H	L	N	L	G	D	S	H	G	N	A	A	Y
Secondary structure
SS confidence
Disorder												?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	G	I	D	P	Y	F	D	D	L	F	L	M	A	A	E	R	R	F	L	S	V	E	R	I	V	A	T	E	E	L	V	K	S	V	P	P	Q	A	L	L	V	N	R	M	M	V	D	A	I	V	E	A	P	G	G	A	H	F	T
Secondary structure
SS confidence
Disorder																															?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.
Sequence		T	A	A	P	D	Y	G	R	D	E	Q	F	Q	R	H	Y	A	E	A	A	S	T	Q	V	G	W	Q	Q	F	V	H	T	Y	L	S	G	T	E	A	D	Y	Q	A	A	V	H	N	F	G	A	S	R
Secondary structure
SS confidence
Disorder																						?	?																									?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 11%) Alpha helix ( 30%) Beta strand ( 25%)

Rank Aligned region

PDB 6co9 chain A Region: 2 - 292 Aligned: 291 Modelled: 291 Confidence: 100.0% Identity: 76% PDB header:hydrolase Chain: A: PDB Molecule:probable coa-transferase alpha subunit; PDBTitle: crystal structure of rhodococcus jostii rha1 ipdab cochea-coa complex Phyre2 PDB 1poi chain A Region: 3 - 292 Aligned: 286 Modelled: 290 Confidence: 100.0% Identity: 27% Fold: NagB/RpiA/CoA transferase-like Superfamily: NagB/RpiA/CoA transferase-like Family: CoA transferase alpha subunit-like Phyre2 PDB 5mzy chain A Region: 1 - 274 Aligned: 256 Modelled: 266 Confidence: 100.0% Identity: 29% PDB header:lyase Chain: A: PDB Molecule:glutaconate coa-transferase family, subunit a; PDBTitle: crystal structure of the decarboxylase aiba/aibb in complex with a2 possible transition state analog Phyre2 PDB 2ahu chain A domain 2 Region: 1 - 252 Aligned: 239 Modelled: 252 Confidence: 100.0% Identity: 21% Fold: NagB/RpiA/CoA transferase-like Superfamily: NagB/RpiA/CoA transferase-like Family: CoA transferase alpha subunit-like Phyre2 PDB 1ooy chain A domain 2 Region: 3 - 233 Aligned: 221 Modelled: 230 Confidence: 100.0% Identity: 23% Fold: NagB/RpiA/CoA transferase-like Superfamily: NagB/RpiA/CoA transferase-like Family: CoA transferase alpha subunit-like Phyre2 PDB 3rrl chain C Region: 3 - 238 Aligned: 212 Modelled: 236 Confidence: 100.0% Identity: 25% PDB header:transferase Chain: C: PDB Molecule:succinyl-coa:3-ketoacid-coenzyme a transferase subunit a; PDBTitle: complex structure of 3-oxoadipate coa-transferase subunit a and b from2 helicobacter pylori 26695 Phyre2 PDB 3cdk chain A Region: 4 - 235 Aligned: 211 Modelled: 232 Confidence: 100.0% Identity: 23% PDB header:transferase Chain: A: PDB Molecule:succinyl-coa:3-ketoacid-coenzyme a transferase PDBTitle: crystal structure of the co-expressed succinyl-coa2 transferase a and b complex from bacillus subtilis Phyre2 PDB 2ahv chain C Region: 1 - 247 Aligned: 237 Modelled: 247 Confidence: 100.0% Identity: 22% PDB header:transferase Chain: C: PDB Molecule:putative enzyme ydif; PDBTitle: crystal structure of acyl-coa transferase from e. coli o157:h7 (ydif)-2 thioester complex with coa- 1 Phyre2 PDB 1k6d chain A Region: 1 - 234 Aligned: 211 Modelled: 234 Confidence: 100.0% Identity: 25% Fold: NagB/RpiA/CoA transferase-like Superfamily: NagB/RpiA/CoA transferase-like Family: CoA transferase alpha subunit-like Phyre2 PDB 4kgb chain B Region: 4 - 245 Aligned: 232 Modelled: 242 Confidence: 100.0% Identity: 20% PDB header:transferase Chain: B: PDB Molecule:succinyl-coa:3-ketoacid-coenzyme a transferase; PDBTitle: structure of succinyl-coa: 3-ketoacid coa transferase from drosophila2 melanogaster Phyre2 PDB 1ooy chain A Region: 3 - 234 Aligned: 222 Modelled: 231 Confidence: 100.0% Identity: 23% PDB header:transferase Chain: A: PDB Molecule:succinyl-coa:3-ketoacid-coenzyme a transferase, PDBTitle: succinyl-coa:3-ketoacid coa transferase from pig heart Phyre2 PDB 2hj0 chain A Region: 2 - 258 Aligned: 196 Modelled: 203 Confidence: 100.0% Identity: 18% PDB header:lyase Chain: A: PDB Molecule:putative citrate lyase, alfa subunit; PDBTitle: crystal structure of the putative alfa subunit of citrate lyase in2 complex with citrate from streptococcus mutans, northeast structural3 genomics target smr12 . Phyre2 PDB 3qlk chain B Region: 2 - 235 Aligned: 179 Modelled: 192 Confidence: 100.0% Identity: 22% PDB header:transferase Chain: B: PDB Molecule:coenzyme a transferase; PDBTitle: crystal structure of ripa from yersinia pestis Phyre2 PDB 1xr4 chain B Region: 2 - 259 Aligned: 198 Modelled: 205 Confidence: 99.9% Identity: 23% PDB header:hydrolase/transferase Chain: B: PDB Molecule:putative citrate lyase alpha chain/citrate-acp transferase; PDBTitle: x-ray crystal structure of putative citrate lyase alpha chain/citrate-2 acp transferase [salmonella typhimurium] Phyre2 PDB 4eu4 chain A Region: 1 - 246 Aligned: 188 Modelled: 201 Confidence: 99.9% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:succinyl-coa:acetate coenzyme a transferase; PDBTitle: succinyl-coa: acetate coa-transferase (aarch6) in complex with coa2 (hexagonal lattice) Phyre2 PDB 3gk7 chain A Region: 2 - 261 Aligned: 195 Modelled: 212 Confidence: 99.9% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:4-hydroxybutyrate coa-transferase; PDBTitle: crystal structure of 4-hydroxybutyrate coa-transferase from2 clostridium aminobutyricum Phyre2 PDB 5vit chain P Region: 3 - 234 Aligned: 175 Modelled: 185 Confidence: 99.9% Identity: 18% PDB header:transferase Chain: P: PDB Molecule:mdca; PDBTitle: crystal structure of a pseudomonas malonate decarboxylase hetero-2 tetramer in complex with malonate Phyre2 PDB 2g39 chain A Region: 1 - 254 Aligned: 193 Modelled: 205 Confidence: 99.9% Identity: 16% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:acetyl-coa hydrolase; PDBTitle: crystal structure of coenzyme a transferase from pseudomonas2 aeruginosa Phyre2 PDB 2oas chain A Region: 6 - 260 Aligned: 190 Modelled: 203 Confidence: 99.9% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:4-hydroxybutyrate coenzyme a transferase; PDBTitle: crystal structure of 4-hydroxybutyrate coenzyme a transferase (atoa)2 in complex with coa from shewanella oneidensis, northeast structural3 genomics target sor119. Phyre2 PDB 2nvv chain F Region: 3 - 249 Aligned: 189 Modelled: 202 Confidence: 99.9% Identity: 14% PDB header:hydrolase Chain: F: PDB Molecule:acetyl-coa hydrolase/transferase family protein; PDBTitle: crystal structure of the putative acetyl-coa hydrolase/transferase2 pg1013 from porphyromonas gingivalis, northeast structural genomics3 target pgr16. Phyre2 1 c6co9A_ 2 d1poia_ 3 c5mzyA_ 4 d2ahua2 5 d1ooya2 6 c3rrlC_ 7 c3cdkA_ 8 c2ahvC_ 9 d1k6da_ 10 c4kgbB_ 11 c1ooyA_ 12 c2hj0A_ 13 c3qlkB_ 14 c1xr4B_ 15 c4eu4A_ 16 c3gk7A_ 17 c5vitP_ 18 c2g39A_ 19 c2oasA_ 20 c2nvvF_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99