1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	R	L	I	P	G	C	T	L	V	G	L	M	L	T	L	L	P	A	P	T	S	A	A	G	S	N	T	A	T	T	L	F	P	V	D	E	V	T	Q	L	E	T	H	T	F	L	D	C	H	P	N	G	S	C	D	F	V	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?												?	?	?	?	?	?	?	?	?	?	?							?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	A	N	L	R	T	P	D	G	P	T	G	F	P	P	G	L	W	A	R	Q	T	T	E	I	R	S	T	N	R	L	A	Y	L	D	A	H	A	T	S	Q	F	E	R	V	M	K	A	G	G	S	D	V	I	T	T	V	Y	F	G
Secondary structure
SS confidence
Disorder					?	?	?	?	?																	?	?																						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.
Sequence		E	G	P	P	D	K	Y	Q	T	T	G	V	I	D	S	T	N	W	S	T	G	Q	P	M	T	D	V	N	V	I	V	C	T	H	M	Q	V	V	Y	P	G	V	N	L	T	S	P	S	T	C	A	Q	A	N	F	S
Secondary structure
SS confidence
Disorder										?	?			?	?	?		?	?	?	?	?	?	?																											?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 27%) Alpha helix ( 9%) Beta strand ( 49%)

Rank Aligned region

PDB 1h3g chain A domain 1 Region: 132 - 166 Aligned: 35 Modelled: 33 Confidence: 37.9% Identity: 26% Fold: Immunoglobulin-like beta-sandwich Superfamily: E set domains Family: E-set domains of sugar-utilizing enzymes Phyre2 PDB 5a7y chain A Region: 70 - 126 Aligned: 50 Modelled: 57 Confidence: 37.9% Identity: 12% PDB header:transferase Chain: A: PDB Molecule:trna (adenine(9)-n1)-methyltransferase; PDBTitle: crystal structure of sulfolobus acidocaldarius trm10 in2 complex with s-adenosylhomocysteine Phyre2 PDB 1gtf chain A Region: 147 - 175 Aligned: 26 Modelled: 29 Confidence: 28.3% Identity: 23% Fold: Double-stranded beta-helix Superfamily: TRAP-like Family: Trp RNA-binding attenuation protein (TRAP) Phyre2 PDB 5oev chain B Region: 110 - 152 Aligned: 38 Modelled: 43 Confidence: 19.6% Identity: 11% PDB header:transferase Chain: B: PDB Molecule:glutathione synthetase-like effector 22 (gpa-gss22-apo); PDBTitle: the structure of a glutathione synthetase like-effector (gss22) from2 globodera pallida in apoform. Phyre2 PDB 2hu9 chain B Region: 116 - 152 Aligned: 31 Modelled: 37 Confidence: 19.0% Identity: 23% PDB header:metal transport Chain: B: PDB Molecule:mercuric transport protein periplasmic component; PDBTitle: x-ray structure of the archaeoglobus fulgidus copz n-2 terminal domain Phyre2 PDB 1mzw chain B Region: 117 - 126 Aligned: 10 Modelled: 10 Confidence: 18.6% Identity: 50% PDB header:isomerase Chain: B: PDB Molecule:u4/u6 snrnp 60kda protein; PDBTitle: crystal structure of a u4/u6 snrnp complex between human2 spliceosomal cyclophilin h and a u4/u6-60k peptide Phyre2 PDB 1olt chain A Region: 102 - 124 Aligned: 23 Modelled: 23 Confidence: 17.3% Identity: 13% Fold: TIM beta/alpha-barrel Superfamily: Radical SAM enzymes Family: Oxygen-independent coproporphyrinogen III oxidase HemN Phyre2 PDB 2bzw chain B Region: 74 - 81 Aligned: 8 Modelled: 8 Confidence: 15.6% Identity: 75% PDB header:transcription Chain: B: PDB Molecule:bcl2-antagonist of cell death; PDBTitle: the crystal structure of bcl-xl in complex with full-length bad Phyre2 PDB 5oev chain D Region: 113 - 152 Aligned: 35 Modelled: 40 Confidence: 14.9% Identity: 14% PDB header:transferase Chain: D: PDB Molecule:glutathione synthetase-like effector 22 (gpa-gss22-apo); PDBTitle: the structure of a glutathione synthetase like-effector (gss22) from2 globodera pallida in apoform. Phyre2 PDB 6a0c chain B Region: 61 - 75 Aligned: 15 Modelled: 15 Confidence: 14.3% Identity: 47% PDB header:structural protein Chain: B: PDB Molecule:collagen type iii peptide; PDBTitle: structure of a triple-helix region of human collagen type iii Phyre2 PDB 4mit chain E Region: 65 - 76 Aligned: 12 Modelled: 12 Confidence: 13.9% Identity: 50% PDB header:signaling protein Chain: E: PDB Molecule:serine/threonine protein kinase pak, putative; PDBTitle: crystal structure of e. histolytica racc bound to the ehpak4 pbd Phyre2 PDB 4mit chain G Region: 65 - 76 Aligned: 12 Modelled: 12 Confidence: 13.8% Identity: 50% PDB header:signaling protein Chain: G: PDB Molecule:serine/threonine protein kinase pak, putative; PDBTitle: crystal structure of e. histolytica racc bound to the ehpak4 pbd Phyre2 PDB 6a0c chain A Region: 61 - 75 Aligned: 15 Modelled: 15 Confidence: 13.5% Identity: 47% PDB header:structural protein Chain: A: PDB Molecule:collagen type iii peptide; PDBTitle: structure of a triple-helix region of human collagen type iii Phyre2 PDB 6a0c chain C Region: 61 - 75 Aligned: 15 Modelled: 15 Confidence: 13.5% Identity: 47% PDB header:structural protein Chain: C: PDB Molecule:collagen type iii peptide; PDBTitle: structure of a triple-helix region of human collagen type iii Phyre2 PDB 5anc chain C Region: 58 - 76 Aligned: 19 Modelled: 19 Confidence: 13.1% Identity: 37% PDB header:translation Chain: C: PDB Molecule:60s acidic ribosomal protein p0; PDBTitle: mechanism of eif6 release from the nascent 60s ribosomal subunit Phyre2 PDB 2jwy chain A Region: 57 - 97 Aligned: 41 Modelled: 41 Confidence: 13.1% Identity: 10% PDB header:lipoprotein Chain: A: PDB Molecule:uncharacterized lipoprotein yaji; PDBTitle: solution nmr structure of uncharacterized lipoprotein yaji from2 escherichia coli. northeast structural genomics target er540 Phyre2 PDB 1gyv chain A Region: 70 - 78 Aligned: 9 Modelled: 9 Confidence: 12.7% Identity: 44% Fold: Immunoglobulin-like beta-sandwich Superfamily: Clathrin adaptor appendage domain Family: gamma-adaptin C-terminal appendage domain-like Phyre2 PDB 2mca chain A Region: 80 - 141 Aligned: 62 Modelled: 62 Confidence: 12.1% Identity: 24% PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: nmr structure of the protein yp_002937094.1 from eubacterium rectale Phyre2 PDB 2wyo chain C Region: 110 - 152 Aligned: 38 Modelled: 43 Confidence: 12.0% Identity: 26% PDB header:ligase Chain: C: PDB Molecule:glutathione synthetase; PDBTitle: trypanosoma brucei glutathione synthetase Phyre2 PDB 3iz5 chain S Region: 58 - 76 Aligned: 19 Modelled: 19 Confidence: 11.9% Identity: 37% PDB header:ribosome Chain: S: PDB Molecule:60s ribosomal protein l18a (l18ae); PDBTitle: localization of the large subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome Phyre2 1 d1h3ga1 2 c5a7yA_ 3 d1gtfa_ 4 c5oevB_ 5 c2hu9B_ 6 c1mzwB_ 7 d1olta_ 8 c2bzwB_ 9 c5oevD_ 10 c6a0cB_ 11 c4mitE_ 12 c4mitG_ 13 c6a0cA_ 14 c6a0cC_ 15 c5ancC_ 16 c2jwyA_ 17 d1gyva_ 18 c2mcaA_ 19 c2wyoC_ 20 c3iz5s_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61