1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	G	K	Q	L	A	A	L	A	A	L	V	G	A	C	M	L	A	A	G	C	T	N	V	V	D	G	T	A	V	A	A	D	K	S	G	P	L	H	Q	D	P	I	P	V	S	A	L	E	G	L	L	L	D	L	S	Q	I	N	A
Secondary structure
SS confidence
Disorder		?	?																			?	?					?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?				?			?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	L	G	A	T	S	M	K	V	W	F	N	A	K	A	M	W	D	W	S	K	S	V	A	D	K	N	C	L	A	I	D	G	P	A	Q	E	K	V	Y	A	G	T	G	W	T	A	M	R	G	Q	R	L	D	D	S	I	D	D	S
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?										?	?		?		?	?	?	?														?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		K	K	R	D	H	Y	A	I	Q	A	V	V	G	F	P	T	A	H	D	A	E	E	F	Y	S	S	S	V	Q	S	W	S	S	C	S	N	R	R	F	V	E	V	T	P	G	Q	D	D	A	A	W	T	V	A	D	V	V	N	D	N
Secondary structure
SS confidence
Disorder		?	?	?																														?	?																							?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.
Sequence		G	M	L	S	S	S	Q	V	Q	E	G	G	D	G	W	T	C	Q	R	A	L	T	A	R	N	N	V	T	I	D	I	V	T	C	A	Y	S	Q	P	D	L	V	A	I	G	I	A	N	Q	I	A	A	K	V	A	K	Q
Secondary structure
SS confidence
Disorder										?	?	?	?	?	?	?								?	?										?	?	?	?	?	?	?	?	?										?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 38%) Alpha helix ( 32%) Beta strand ( 25%)

Rank Aligned region

PDB 4esq chain A Region: 41 - 237 Aligned: 192 Modelled: 197 Confidence: 100.0% Identity: 34% PDB header:transferase Chain: A: PDB Molecule:serine/threonine protein kinase; PDBTitle: crystal structure of the extracellular domain of pknh from2 mycobacterium tuberculosis Phyre2 PDB 2b3g chain B Region: 41 - 59 Aligned: 19 Modelled: 19 Confidence: 42.4% Identity: 32% PDB header:replication Chain: B: PDB Molecule:cellular tumor antigen p53; PDBTitle: p53n (fragment 33-60) bound to rpa70n Phyre2 PDB 2fiu chain A domain 1 Region: 130 - 146 Aligned: 17 Modelled: 17 Confidence: 40.2% Identity: 35% Fold: Ferredoxin-like Superfamily: Dimeric alpha+beta barrel Family: Atu0297-like Phyre2 PDB 3lo3 chain E Region: 130 - 146 Aligned: 17 Modelled: 17 Confidence: 40.2% Identity: 35% PDB header:structure genomics, unknown function Chain: E: PDB Molecule:uncharacterized conserved protein; PDBTitle: the crystal structure of a conserved functionally unknown protein from2 colwellia psychrerythraea 34h. Phyre2 PDB 1jjc chain B domain 1 Region: 50 - 97 Aligned: 48 Modelled: 48 Confidence: 32.1% Identity: 17% Fold: Putative DNA-binding domain Superfamily: Putative DNA-binding domain Family: Domains B1 and B5 of PheRS-beta, PheT Phyre2 PDB 2l14 chain B Region: 41 - 59 Aligned: 19 Modelled: 19 Confidence: 30.1% Identity: 32% PDB header:protein binding Chain: B: PDB Molecule:cellular tumor antigen p53; PDBTitle: structure of cbp nuclear coactivator binding domain in complex with2 p53 tad Phyre2 PDB 5uz5 chain C Region: 129 - 152 Aligned: 24 Modelled: 24 Confidence: 27.6% Identity: 25% PDB header:nuclear protein/rna Chain: C: PDB Molecule:u1 small nuclear ribonucleoprotein a,tap tag; PDBTitle: s. cerevisiae u1 snrnp Phyre2 PDB 3i08 chain D Region: 134 - 150 Aligned: 17 Modelled: 17 Confidence: 23.6% Identity: 24% PDB header:signaling protein Chain: D: PDB Molecule:neurogenic locus notch homolog protein 1; PDBTitle: crystal structure of the s1-cleaved notch1 negative2 regulatory region (nrr) Phyre2 PDB 2ly4 chain B Region: 35 - 58 Aligned: 24 Modelled: 24 Confidence: 21.9% Identity: 25% PDB header:nuclear protein/antitumour protein Chain: B: PDB Molecule:cellular tumor antigen p53; PDBTitle: hmgb1-facilitated p53 dna binding occurs via hmg-box/p532 transactivation domain interaction and is regulated by the acidic3 tail Phyre2 PDB 3dca chain C Region: 130 - 146 Aligned: 17 Modelled: 13 Confidence: 19.2% Identity: 12% PDB header:structural genomics, unknown function Chain: C: PDB Molecule:rpa0582; PDBTitle: crystal structure of the rpa0582- protein of unknown2 function from rhodopseudomonas palustris- a structural3 genomics target Phyre2 PDB 2mzd chain B Region: 43 - 59 Aligned: 17 Modelled: 17 Confidence: 11.1% Identity: 29% PDB header:protein binding Chain: B: PDB Molecule:cellular tumor antigen p53; PDBTitle: characterization of the p300 taz2-p53 tad2 complex and comparison with2 the p300 taz2-p53 tad1 complex Phyre2 PDB 6ehi chain I Region: 129 - 154 Aligned: 26 Modelled: 26 Confidence: 9.7% Identity: 12% PDB header:dna binding protein Chain: I: PDB Molecule:nuclease nuct; PDBTitle: nuct from helicobacter pylori Phyre2 PDB 2jp3 chain A Region: 2 - 20 Aligned: 19 Modelled: 19 Confidence: 9.2% Identity: 21% PDB header:transcription Chain: A: PDB Molecule:fxyd domain-containing ion transport regulator 4; PDBTitle: solution structure of the human fxyd4 (chif) protein in sds2 micelles Phyre2 PDB 2n8f chain A Region: 150 - 157 Aligned: 8 Modelled: 8 Confidence: 9.1% Identity: 38% PDB header:toxin Chain: A: PDB Molecule:spider toxin pi-hexatoxin-hi1a; PDBTitle: chemical shift assignments and structure calculation of spider toxin2 pi-hexatoxin-hi1a Phyre2 PDB 2ahm chain G Region: 152 - 200 Aligned: 44 Modelled: 49 Confidence: 8.0% Identity: 25% PDB header:viral protein, replication Chain: G: PDB Molecule:replicase polyprotein 1ab, heavy chain; PDBTitle: crystal structure of sars-cov super complex of non-structural2 proteins: the hexadecamer Phyre2 PDB 2jo1 chain A Region: 2 - 20 Aligned: 19 Modelled: 19 Confidence: 7.5% Identity: 16% PDB header:hydrolase regulator Chain: A: PDB Molecule:phospholemman; PDBTitle: structure of the na,k-atpase regulatory protein fxyd1 in2 micelles Phyre2 PDB 2mkv chain A Region: 2 - 20 Aligned: 19 Modelled: 19 Confidence: 7.1% Identity: 37% PDB header:transport protein Chain: A: PDB Molecule:sodium/potassium-transporting atpase subunit gamma; PDBTitle: structure of the na,k-atpase regulatory protein fxyd2b in micelles Phyre2 PDB 2dmw chain A Region: 189 - 237 Aligned: 45 Modelled: 49 Confidence: 7.0% Identity: 24% PDB header:membrane protein Chain: A: PDB Molecule:synaptobrevin-like 1 variant; PDBTitle: solution structure of the longin domain of synaptobrevin-2 like protein 1 Phyre2 PDB 2zxe chain G Region: 2 - 20 Aligned: 19 Modelled: 19 Confidence: 6.5% Identity: 37% PDB header:hydrolase/transport protein Chain: G: PDB Molecule:phospholemman-like protein; PDBTitle: crystal structure of the sodium - potassium pump in the e2.2k+.pi2 state Phyre2 PDB 1xkm chain D Region: 139 - 154 Aligned: 16 Modelled: 16 Confidence: 6.0% Identity: 13% PDB header:antibiotic Chain: D: PDB Molecule:distinctin chain b; PDBTitle: nmr structure of antimicrobial peptide distinctin in water Phyre2 1 c4esqA_ 2 c2b3gB_ 3 d2fiua1 4 c3lo3E_ 5 d1jjcb1 6 c2l14B_ 7 c5uz5C_ 8 c3i08D_ 9 c2ly4B_ 10 c3dcaC_ 11 c2mzdB_ 12 c6ehiI_ 13 c2jp3A_ 14 c2n8fA_ 15 c2ahmG_ 16 c2jo1A_ 17 c2mkvA_ 18 c2dmwA_ 19 c2zxeG_ 20 c1xkmD_ 21 22 23 24