1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	G	W	I	G	D	P	I	W	L	E	E	V	L	R	P	A	L	G	E	R	L	R	V	L	D	G	W	R	E	R	G	H	G	D	F	R	D	I	R	G	V	M	W	H	H	T	G	N	S	R	E	T	A	K	S	I	A	R	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																								?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	P	D	L	P	G	P	L	A	N	L	H	I	A	H	S	G	V	V	T	I	V	A	V	G	V	C	W	H	A	G	R	G	S	Y	P	W	L	P	T	D	N	A	N	W	H	M	I	G	V	E	C	A	W	P	T	I	R	R	D
Secondary structure
SS confidence
Disorder																																																											?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	S	Y	D	A	G	E	R	W	P	D	A	Q	I	V	S	M	R	D	V	A	A	A	L	T	L	K	L	G	Y	G	P	E	R	N	I	G	H	K	E	Y	A	G	A	A	Q	G	K	W	D	P	G	N	L	S	M	D	W	F	R
Secondary structure
SS confidence
Disorder			?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	E	V	A	K	D	T	R	G	E	F	D	H	P	L	T	P	P	P	A	V	I	A	R	P	P	I	L	P	K	P	R	N	P	R	D	D	R	I	L	L	E	E	V	W	D	Q	L	R	G	I	E	G	R	G	W	P	V	L	G
Secondary structure
SS confidence
Disorder								?	?	?	?	?	?	?	?	?	?	?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?													?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.
Sequence		D	K	T	I	V	D	Y	L	A	E	L	G	N	K	V	D	A	L	A	A	K	L	D	A	R	E	G	L	D	R	P	S	D	T	R
Secondary structure
SS confidence
Disorder																						?				?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 25%) Alpha helix ( 34%) Beta strand ( 12%)

Rank Aligned region

PDB 2bh7 chain A Region: 39 - 265 Aligned: 217 Modelled: 227 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:n-acetylmuramoyl-l-alanine amidase; PDBTitle: crystal structure of a semet derivative of amid at 2.22 angstroms Phyre2 PDB 4bxd chain B Region: 38 - 265 Aligned: 216 Modelled: 220 Confidence: 100.0% Identity: 19% PDB header:hydrolase/peptide Chain: B: PDB Molecule:ampdh3; PDBTitle: crystal structure of ampdh3 from pseudomonas aeruginosa in2 complex with tetrasaccharide pentapeptide Phyre2 PDB 4bol chain A Region: 39 - 261 Aligned: 214 Modelled: 219 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:ampdh2; PDBTitle: crystal structure of ampdh2 from pseudomonas aeruginosa in2 complex with pentapeptide Phyre2 PDB 1j3g chain A Region: 22 - 185 Aligned: 151 Modelled: 164 Confidence: 100.0% Identity: 26% Fold: N-acetylmuramoyl-L-alanine amidase-like Superfamily: N-acetylmuramoyl-L-alanine amidase-like Family: N-acetylmuramoyl-L-alanine amidase-like Phyre2 PDB 2bgx chain A domain 2 Region: 22 - 186 Aligned: 161 Modelled: 163 Confidence: 100.0% Identity: 17% Fold: N-acetylmuramoyl-L-alanine amidase-like Superfamily: N-acetylmuramoyl-L-alanine amidase-like Family: N-acetylmuramoyl-L-alanine amidase-like Phyre2 PDB 3hma chain A Region: 26 - 184 Aligned: 137 Modelled: 153 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:n-acetylmuramoyl-l-alanine amidase xlya; PDBTitle: amidase from bacillus subtilis Phyre2 PDB 1yb0 chain A domain 1 Region: 39 - 185 Aligned: 129 Modelled: 147 Confidence: 99.9% Identity: 16% Fold: N-acetylmuramoyl-L-alanine amidase-like Superfamily: N-acetylmuramoyl-L-alanine amidase-like Family: N-acetylmuramoyl-L-alanine amidase-like Phyre2 PDB 4ivv chain A Region: 30 - 184 Aligned: 137 Modelled: 147 Confidence: 99.9% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:autolysin; PDBTitle: catalytic amidase domain of the major autolysin lyta from2 streptococcus pneumaniae Phyre2 PDB 4ols chain A Region: 39 - 188 Aligned: 134 Modelled: 146 Confidence: 99.9% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:endolysin; PDBTitle: the amidase-2 domain of lysgh15 Phyre2 PDB 1sk4 chain A Region: 21 - 186 Aligned: 142 Modelled: 166 Confidence: 99.9% Identity: 18% Fold: N-acetylmuramoyl-L-alanine amidase-like Superfamily: N-acetylmuramoyl-L-alanine amidase-like Family: N-acetylmuramoyl-L-alanine amidase-like Phyre2 PDB 1yck chain A domain 1 Region: 21 - 186 Aligned: 141 Modelled: 157 Confidence: 99.9% Identity: 19% Fold: N-acetylmuramoyl-L-alanine amidase-like Superfamily: N-acetylmuramoyl-L-alanine amidase-like Family: N-acetylmuramoyl-L-alanine amidase-like Phyre2 PDB 2xz4 chain A Region: 21 - 192 Aligned: 146 Modelled: 172 Confidence: 99.9% Identity: 13% PDB header:immune system Chain: A: PDB Molecule:peptidoglycan-recognition protein lf; PDBTitle: crystal structure of the lfz ectodomain of the2 peptidoglycan recognition protein lf Phyre2 PDB 2rkq chain A Region: 20 - 192 Aligned: 147 Modelled: 171 Confidence: 99.9% Identity: 12% PDB header:immune system Chain: A: PDB Molecule:peptidoglycan-recognition protein-sd; PDBTitle: crystal structure of drosophila peptidoglycan recognition2 protein sd (pgrp-sd) Phyre2 PDB 1oht chain A Region: 20 - 186 Aligned: 141 Modelled: 157 Confidence: 99.9% Identity: 18% Fold: N-acetylmuramoyl-L-alanine amidase-like Superfamily: N-acetylmuramoyl-L-alanine amidase-like Family: N-acetylmuramoyl-L-alanine amidase-like Phyre2 PDB 1oht chain A Region: 20 - 186 Aligned: 141 Modelled: 157 Confidence: 99.9% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:cg14704 protein; PDBTitle: peptidoglycan recognition protein-lb Phyre2 PDB 2cb3 chain A domain 1 Region: 21 - 186 Aligned: 140 Modelled: 164 Confidence: 99.9% Identity: 14% Fold: N-acetylmuramoyl-L-alanine amidase-like Superfamily: N-acetylmuramoyl-L-alanine amidase-like Family: N-acetylmuramoyl-L-alanine amidase-like Phyre2 PDB 2f2l chain X domain 1 Region: 22 - 192 Aligned: 147 Modelled: 160 Confidence: 99.9% Identity: 14% Fold: N-acetylmuramoyl-L-alanine amidase-like Superfamily: N-acetylmuramoyl-L-alanine amidase-like Family: N-acetylmuramoyl-L-alanine amidase-like Phyre2 PDB 1lba chain A Region: 38 - 179 Aligned: 122 Modelled: 141 Confidence: 99.9% Identity: 24% Fold: N-acetylmuramoyl-L-alanine amidase-like Superfamily: N-acetylmuramoyl-L-alanine amidase-like Family: N-acetylmuramoyl-L-alanine amidase-like Phyre2 PDB 3lat chain B Region: 25 - 185 Aligned: 140 Modelled: 150 Confidence: 99.9% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:bifunctional autolysin; PDBTitle: crystal structure of staphylococcus peptidoglycan hydrolase2 amie Phyre2 PDB 5xz3 chain D Region: 21 - 192 Aligned: 146 Modelled: 171 Confidence: 99.8% Identity: 14% PDB header:immune system Chain: D: PDB Molecule:peptidoglycan-recognition protein; PDBTitle: the x-ray structure of apis mellifera pgrp-sa Phyre2 1 c2bh7A_ 2 c4bxdB_ 3 c4bolA_ 4 d1j3ga_ 5 d2bgxa2 6 c3hmaA_ 7 d1yb0a1 8 c4ivvA_ 9 c4olsA_ 10 d1sk4a_ 11 d1ycka1 12 c2xz4A_ 13 c2rkqA_ 14 d1ohta_ 15 c1ohtA_ 16 d2cb3a1 17 d2f2lx1 18 d1lbaa_ 19 c3latB_ 20 c5xz3D_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99