1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	A	P	L	R	F	G	V	F	I	T	P	F	H	P	T	G	Q	S	P	T	V	A	L	Q	Y	D	M	E	R	V	V	A	L	D	R	L	G	Y	D	E	A	W	F	G	E	H	H	S	G	G	Y	E	L	I	A	C	P	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?										?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	F	I	A	A	A	A	E	R	T	T	H	I	R	L	G	T	G	V	V	S	L	P	Y	H	H	P	L	M	V	A	D	R	W	V	L	L	D	H	L	T	R	G	R	V	M	F	G	T	G	P	G	A	L	P	S	D	A	Y	M
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		M	G	I	D	P	V	E	Q	R	R	M	M	Q	E	S	L	E	A	I	L	A	L	F	R	A	A	P	D	E	R	I	D	R	H	S	D	W	F	T	L	R	E	A	Q	L	H	I	R	P	Y	T	W	P	Y	P	E	I	A	T	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	M	I	S	P	S	G	P	R	L	A	G	A	L	G	T	S	L	L	S	L	S	M	S	V	P	G	G	Y	A	A	L	E	T	A	W	G	V	V	R	E	Q	A	A	K	A	G	R	G	E	P	D	R	A	D	W	R	V	L	S
Secondary structure
SS confidence
Disorder																																															?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		I	M	H	L	S	D	S	R	D	Q	A	I	D	D	C	T	Y	G	L	P	D	F	S	R	Y	F	G	A	A	G	F	V	P	L	A	N	T	V	E	G	T	Q	S	S	R	E	F	V	E	Q	Y	A	A	K	G	N	C	C	I	G
Secondary structure
SS confidence
Disorder																														?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		T	P	D	D	A	I	A	H	I	E	D	L	L	H	R	S	G	G	F	G	T	L	L	L	L	G	H	D	W	A	P	P	P	A	T	F	H	S	Y	E	L	F	A	R	A	V	I	P	Y	F	K	G	Q	L	A	A	P	R	A	S
Secondary structure
SS confidence
Disorder																																																								?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.
Sequence		H	E	W	A	R	G	K	R	D	Q	L	I	G	R	A	G	E	A	V	V	K	A	I	T	E	H	V	A	E	Q	G	E	A	G	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																					?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 11%) Alpha helix ( 46%) Beta strand ( 15%) TM helix ( 4%) (View membrane topology prediction)

Rank Aligned region

PDB 1luc chain A Region: 5 - 353 Aligned: 325 Modelled: 334 Confidence: 100.0% Identity: 22% Fold: TIM beta/alpha-barrel Superfamily: Bacterial luciferase-like Family: Bacterial luciferase (alkanal monooxygenase) Phyre2 PDB 2wgk chain A Region: 4 - 351 Aligned: 339 Modelled: 348 Confidence: 100.0% Identity: 25% PDB header:oxidoreductase Chain: A: PDB Molecule:3,6-diketocamphane 1,6 monooxygenase; PDBTitle: type ii baeyer-villiger monooxygenase oxygenating2 constituent of 3,6-diketocamphane 1,6 monooxygenase from3 pseudomonas putida Phyre2 PDB 2i7g chain A Region: 5 - 355 Aligned: 337 Modelled: 350 Confidence: 100.0% Identity: 21% PDB header:oxidoreductase Chain: A: PDB Molecule:monooxygenase; PDBTitle: crystal structure of monooxygenase from agrobacterium tumefaciens Phyre2 PDB 1luc chain B Region: 5 - 347 Aligned: 320 Modelled: 328 Confidence: 100.0% Identity: 17% Fold: TIM beta/alpha-barrel Superfamily: Bacterial luciferase-like Family: Bacterial luciferase (alkanal monooxygenase) Phyre2 PDB 6fri chain D Region: 5 - 346 Aligned: 319 Modelled: 327 Confidence: 100.0% Identity: 17% PDB header:oxidoreductase Chain: D: PDB Molecule:alkanal monooxygenase beta chain; PDBTitle: structure of luxb from photobacterium leiognathi Phyre2 PDB 5tlc chain A Region: 5 - 367 Aligned: 348 Modelled: 360 Confidence: 100.0% Identity: 21% PDB header:oxidoreductase Chain: A: PDB Molecule:dibenzothiophene desulfurization enzyme a; PDBTitle: crystal structure of bdsa from bacillus subtilis wu-s2b Phyre2 PDB 1tvl chain A Region: 5 - 367 Aligned: 341 Modelled: 361 Confidence: 100.0% Identity: 18% Fold: TIM beta/alpha-barrel Superfamily: Bacterial luciferase-like Family: Ssud-like monoxygenases Phyre2 PDB 1tvl chain A Region: 5 - 367 Aligned: 341 Modelled: 361 Confidence: 100.0% Identity: 18% PDB header:oxidoreductase Chain: A: PDB Molecule:protein ytnj; PDBTitle: structure of ytnj from bacillus subtilis Phyre2 PDB 3rao chain B Region: 5 - 357 Aligned: 334 Modelled: 353 Confidence: 100.0% Identity: 16% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative luciferase-like monooxygenase; PDBTitle: crystal structure of the luciferase-like monooxygenase from bacillus2 cereus atcc 10987. Phyre2 PDB 3sdo chain B Region: 2 - 367 Aligned: 348 Modelled: 358 Confidence: 100.0% Identity: 20% PDB header:oxidoreductase Chain: B: PDB Molecule:nitrilotriacetate monooxygenase; PDBTitle: structure of a nitrilotriacetate monooxygenase from burkholderia2 pseudomallei Phyre2 PDB 1ezw chain A Region: 3 - 351 Aligned: 322 Modelled: 349 Confidence: 100.0% Identity: 22% Fold: TIM beta/alpha-barrel Superfamily: Bacterial luciferase-like Family: F420 dependent oxidoreductases Phyre2 PDB 3b9n chain B Region: 1 - 367 Aligned: 352 Modelled: 367 Confidence: 100.0% Identity: 21% PDB header:oxidoreductase Chain: B: PDB Molecule:alkane monoxygenase; PDBTitle: crystal structure of long-chain alkane monooxygenase (lada) Phyre2 PDB 5w4z chain A Region: 4 - 367 Aligned: 349 Modelled: 364 Confidence: 100.0% Identity: 20% PDB header:flavoprotein Chain: A: PDB Molecule:riboflavin lyase; PDBTitle: crystal structure of riboflavin lyase (rcae) with modified fmn and2 substrate riboflavin Phyre2 PDB 5dqp chain A Region: 5 - 367 Aligned: 348 Modelled: 363 Confidence: 100.0% Identity: 16% PDB header:oxidoreductase Chain: A: PDB Molecule:edta monooxygenase; PDBTitle: edta monooxygenase (emoa) from chelativorans sp. bnc1 Phyre2 PDB 1z69 chain D Region: 5 - 349 Aligned: 314 Modelled: 345 Confidence: 100.0% Identity: 19% PDB header:oxidoreductase Chain: D: PDB Molecule:coenzyme f420-dependent n(5),n(10)- PDBTitle: crystal structure of methylenetetrahydromethanopterin2 reductase (mer) in complex with coenzyme f420 Phyre2 PDB 1nqk chain A Region: 3 - 362 Aligned: 334 Modelled: 360 Confidence: 100.0% Identity: 18% Fold: TIM beta/alpha-barrel Superfamily: Bacterial luciferase-like Family: Ssud-like monoxygenases Phyre2 PDB 5wan chain A Region: 2 - 357 Aligned: 323 Modelled: 339 Confidence: 100.0% Identity: 18% PDB header:oxidoreductase Chain: A: PDB Molecule:pyrimidine monooxygenase ruta; PDBTitle: crystal structure of a flavoenzyme ruta in the pyrimidine catabolic2 pathway Phyre2 PDB 6ak1 chain B Region: 5 - 367 Aligned: 348 Modelled: 363 Confidence: 100.0% Identity: 22% PDB header:oxidoreductase Chain: B: PDB Molecule:dimethyl-sulfide monooxygenase; PDBTitle: crystal structure of dmoa from hyphomicrobium sulfonivorans Phyre2 PDB 1f07 chain A Region: 5 - 350 Aligned: 309 Modelled: 346 Confidence: 100.0% Identity: 21% Fold: TIM beta/alpha-barrel Superfamily: Bacterial luciferase-like Family: F420 dependent oxidoreductases Phyre2 PDB 3c8n chain B Region: 5 - 352 Aligned: 323 Modelled: 348 Confidence: 100.0% Identity: 22% PDB header:oxidoreductase Chain: B: PDB Molecule:probable f420-dependent glucose-6-phosphate dehydrogenase PDBTitle: crystal structure of apo-fgd1 from mycobacterium tuberculosis Phyre2 1 d1luca_ 2 c2wgkA_ 3 c2i7gA_ 4 d1lucb_ 5 c6friD_ 6 c5tlcA_ 7 d1tvla_ 8 c1tvlA_ 9 c3raoB_ 10 c3sdoB_ 11 d1ezwa_ 12 c3b9nB_ 13 c5w4zA_ 14 c5dqpA_ 15 c1z69D_ 16 d1nqka_ 17 c5wanA_ 18 c6ak1B_ 19 d1f07a_ 20 c3c8nB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104