1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	T	G	A	S	E	L	T	L	G	N	T	V	D	W	E	F	A	A	S	V	G	E	R	L	A	R	P	A	P	P	S	T	E	Y	T	R	R	Q	V	I	D	E	L	T	V	A	A	E	K	A	E	P	P	V	R	D	V	T	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?														?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	I	A	D	G	V	V	P	P	A	R	V	V	D	R	P	A	W	I	R	S	A	A	E	S	M	R	A	M	T	H	G	S	A	K	P	R	G	F	L	T	G	R	I	T	G	A	Q	T	G	A	V	L	A	F	V	A	S	G	I
Secondary structure
SS confidence
Disorder			?		?	?	?		?																							?	?				?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	G	Q	Y	D	P	F	G	A	A	G	E	G	C	L	L	L	V	Y	P	N	V	I	A	V	E	R	Q	L	R	V	E	P	S	D	F	R	L	W	V	C	L	H	E	V	T	H	R	V	Q	F	T	A	N	P	W	L	S	G	Y
Secondary structure
SS confidence
Disorder										?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		M	S	Q	A	L	N	L	L	T	F	E	P	V	D	D	I	G	R	V	V	S	R	L	A	D	F	I	R	S	R	G	H	G	T	D	D	S	E	V	N	P	S	G	I	L	G	L	V	R	A	V	Q	S	E	P	Q	R	K	A	L
Secondary structure
SS confidence
Disorder											?	?	?	?	?	?												?	?	?	?	?	?	?	?	?	?			?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		D	Q	L	L	V	L	G	T	L	L	E	G	H	A	E	H	V	M	D	A	V	G	P	M	V	V	P	S	V	A	T	I	R	R	R	F	D	D	R	R	H	H	K	Q	P	P	L	Q	R	L	V	R	A	L	L	G	F	D	A	K
Secondary structure
SS confidence
Disorder																													?													?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence		L	S	Q	Y	T	R	G	K	A	F	V	D	H	V	V	D	R	A	G	M	K	L	F	N	T	I	W	S	G	P	E	T	L	P	L	P	A	E	I	E	N	P	Q	R	W	I	D	R	V	L
Secondary structure
SS confidence
Disorder																																																	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 21%) Alpha helix ( 69%) Beta strand ( 2%)

Rank Aligned region

PDB 3cmn chain A Region: 12 - 349 Aligned: 294 Modelled: 297 Confidence: 100.0% Identity: 33% PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of a putative hydrolase with a novel fold2 from chloroflexus aurantiacus Phyre2 PDB 3cmn chain A domain 1 Region: 12 - 349 Aligned: 294 Modelled: 296 Confidence: 100.0% Identity: 33% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Caur0242-like Phyre2 PDB 4jiu chain A Region: 153 - 175 Aligned: 23 Modelled: 23 Confidence: 49.3% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:proabylysin; PDBTitle: crystal structure of the metallopeptidase zymogen of pyrococcus abyssi2 abylysin Phyre2 PDB 1nkz chain B Region: 154 - 177 Aligned: 24 Modelled: 24 Confidence: 46.1% Identity: 38% Fold: Light-harvesting complex subunits Superfamily: Light-harvesting complex subunits Family: Light-harvesting complex subunits Phyre2 PDB 4clv chain B Region: 102 - 243 Aligned: 125 Modelled: 142 Confidence: 41.8% Identity: 11% PDB header:metal binding protein Chain: B: PDB Molecule:nickel-cobalt-cadmium resistance protein nccx; PDBTitle: crystal structure of dodecylphosphocholine-solubilized nccx2 from cupriavidus metallidurans 31a Phyre2 PDB 4jix chain B Region: 153 - 167 Aligned: 15 Modelled: 15 Confidence: 41.7% Identity: 27% PDB header:hydrolase Chain: B: PDB Molecule:projannalysin; PDBTitle: crystal structure of the metallopeptidase zymogen of2 methanocaldococcus jannaschii jannalysin Phyre2 PDB 3u1d chain A Region: 312 - 340 Aligned: 29 Modelled: 29 Confidence: 33.1% Identity: 14% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the structure of a protein with a gntr superfamily winged-helix-turn-2 helix domain from halomicrobium mukohataei. Phyre2 PDB 3cqx chain D Region: 179 - 251 Aligned: 72 Modelled: 73 Confidence: 26.5% Identity: 15% PDB header:chaperone Chain: D: PDB Molecule:bag family molecular chaperone regulator 2; PDBTitle: chaperone complex Phyre2 PDB 5xbv chain A Region: 153 - 190 Aligned: 38 Modelled: 38 Confidence: 26.2% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:wss1p; PDBTitle: crystal structure of wss1 mutant from saccharomyces cerevisiae Phyre2 PDB 4b24 chain A Region: 279 - 341 Aligned: 51 Modelled: 63 Confidence: 23.2% Identity: 16% PDB header:hydrolase/dna Chain: A: PDB Molecule:probable dna-3-methyladenine glycosylase 2; PDBTitle: unprecedented sculpting of dna at abasic sites by dna glycoslase2 homolog mag2 Phyre2 PDB 5lde chain B Region: 142 - 161 Aligned: 20 Modelled: 20 Confidence: 21.2% Identity: 20% PDB header:viral protein Chain: B: PDB Molecule:immunoglobulin g-binding protein g,viral flice protein; PDBTitle: crystal structure of a vflip-ikkgamma stapled peptide dimer Phyre2 PDB 1a2z chain A Region: 154 - 205 Aligned: 52 Modelled: 52 Confidence: 21.0% Identity: 12% Fold: Phosphorylase/hydrolase-like Superfamily: Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) Family: Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) Phyre2 PDB 2cwl chain A domain 1 Region: 154 - 174 Aligned: 21 Modelled: 21 Confidence: 20.6% Identity: 5% Fold: Ferritin-like Superfamily: Ferritin-like Family: Manganese catalase (T-catalase) Phyre2 PDB 1iof chain A Region: 154 - 208 Aligned: 55 Modelled: 55 Confidence: 20.4% Identity: 11% Fold: Phosphorylase/hydrolase-like Superfamily: Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) Family: Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) Phyre2 PDB 5z5m chain B Region: 170 - 243 Aligned: 66 Modelled: 74 Confidence: 19.1% Identity: 9% PDB header:lyase Chain: B: PDB Molecule:predicted protein; PDBTitle: crystal structure of (s)-allantoin synthase Phyre2 PDB 3zdo chain C Region: 234 - 258 Aligned: 25 Modelled: 25 Confidence: 18.5% Identity: 40% PDB header:viral protein Chain: C: PDB Molecule:phosphoprotein; PDBTitle: tetramerization domain of measles virus phosphoprotein Phyre2 PDB 1e3o chain C domain 2 Region: 107 - 124 Aligned: 18 Modelled: 18 Confidence: 18.1% Identity: 11% Fold: lambda repressor-like DNA-binding domains Superfamily: lambda repressor-like DNA-binding domains Family: POU-specific domain Phyre2 PDB 6et5 chain U Region: 156 - 179 Aligned: 24 Modelled: 24 Confidence: 14.8% Identity: 25% PDB header:photosynthesis Chain: U: PDB Molecule:light-harvesting protein b-1015 gamma chain; PDBTitle: reaction centre light harvesting complex 1 from blc. virids Phyre2 PDB 5mtw chain D Region: 164 - 188 Aligned: 25 Modelled: 25 Confidence: 14.8% Identity: 16% PDB header:chaperone Chain: D: PDB Molecule:secb-like chaperone rv1957; PDBTitle: mycobacterium tuberculosis rv1957 secb-like chaperone in complex with2 a chad peptide from rv1956 higa1 antitoxin Phyre2 PDB 1mqr chain A Region: 123 - 176 Aligned: 43 Modelled: 43 Confidence: 14.8% Identity: 26% PDB header:hydrolase Chain: A: PDB Molecule:alpha-d-glucuronidase; PDBTitle: the crystal structure of alpha-d-glucuronidase (e386q) from bacillus2 stearothermophilus t-6 Phyre2 1 c3cmnA_ 2 d3cmna1 3 c4jiuA_ 4 d1nkzb_ 5 c4clvB_ 6 c4jixB_ 7 c3u1dA_ 8 c3cqxD_ 9 c5xbvA_ 10 c4b24A_ 11 c5ldeB_ 12 d1a2za_ 13 d2cwla1 14 d1iofa_ 15 c5z5mB_ 16 c3zdoC_ 17 d1e3oc2 18 c6et5u_ 19 c5mtwD_ 20 c1mqrA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70