1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	P	A	P	R	M	P	R	V	A	L	V	A	V	L	L	I	T	V	Q	L	V	V	R	V	V	L	A	F	G	G	Y	F	Y	W	D	D	L	I	L	V	G	R	A	G	T	G	G	L	L	S	P	S	Y	L	F	D	D	H	D
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																							?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	H	V	M	P	G	A	F	L	V	A	G	A	I	I	R	V	A	P	L	V	W	T	G	P	A	I	S	L	V	V	L	Q	L	L	E	S	L	A	L	L	R	A	L	Y	V	I	S	S	W	R	P	V	L	L	I	P	L	T	F
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	L	F	T	P	L	A	V	P	G	F	A	W	W	A	A	A	L	N	S	L	P	M	L	A	A	L	A	W	V	C	A	D	A	I	L	L	V	R	T	G	N	H	R	Y	A	V	T	G	V	L	V	Y	L	G	G	L	L	F	F
Secondary structure
SS confidence
Disorder																			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		E	K	A	A	V	I	P	F	V	S	F	A	V	A	A	L	Q	C	H	V	R	G	D	R	S	A	L	A	T	V	W	R	A	G	V	R	L	W	T	P	S	L	A	L	T	V	G	W	V	A	L	Y	L	A	V	V	D	Q	R	R
Secondary structure
SS confidence
Disorder			?	?																			?	?	?	?	?	?	?	?	?		?	?		?																		?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		W	S	S	D	L	S	M	T	W	D	L	L	C	R	S	V	T	H	G	I	V	P	A	L	A	G	G	P	W	D	W	A	R	W	A	P	A	S	P	W	A	T	P	P	A	V	V	M	V	L	G	W	L	V	L	I	A	V	L	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?																																?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		L	S	L	V	R	K	R	R	I	G	P	V	W	L	T	A	A	G	Y	A	V	A	C	Q	V	P	I	F	L	M	R	S	S	P	F	T	A	L	E	L	A	Q	T	L	R	Y	F	P	D	L	V	V	V	L	A	L	L	A	A	V
Secondary structure
SS confidence
Disorder																															?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		A	L	Q	A	P	N	R	A	G	T	R	W	L	D	A	S	P	A	R	A	V	A	T	V	A	S	A	V	L	F	L	T	S	S	L	Y	S	T	A	T	F	L	A	S	W	R	D	N	P	T	E	G	Y	L	K	N	A	Q	A	S
Secondary structure
SS confidence
Disorder							?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		L	A	A	A	A	S	G	A	P	L	L	D	Q	E	V	D	P	L	V	L	Q	R	V	A	W	P	E	N	L	A	S	H	M	F	A	L	L	R	V	R	P	E	F	A	T	T	T	T	Q	L	R	M	F	T	S	T	G	R	L	V
Secondary structure
SS confidence
Disorder				?		?	?		?	?																							?	?		?	?	?	?	?	?	?	?	?	?	?	?	?	?							?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		D	A	K	V	T	W	V	R	T	I	I	A	G	P	V	P	Q	C	G	Y	F	V	Q	P	D	R	P	E	R	L	I	L	D	G	P	L	L	P	G	D	W	T	V	E	L	N	Y	L	A	N	S	D	G	S	M	A	L	A	L	S
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?	?	?		?	?													?																								?	?						?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.
Sequence		D	G	P	E	R	K	V	P	V	H	P	G	L	N	R	V	Y	A	R	L	P	G	A	G	D	A	I	T	V	R	A	N	T	T	A	L	S	L	C	I	G	A	A	P	V	G	F	L	A	P	A
Secondary structure
SS confidence
Disorder		?	?	?	?					?																							?		?											?		?		?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 19%) Alpha helix ( 57%) Beta strand ( 9%) TM helix ( 42%) (View membrane topology prediction)

Rank Aligned region

PDB 6p2r chain B Region: 7 - 408 Aligned: 385 Modelled: 402 Confidence: 99.7% Identity: 16% PDB header:transferase Chain: B: PDB Molecule:dolichyl-phosphate-mannose--protein mannosyltransferase 2; PDBTitle: structure of s. cerevisiae protein o-mannosyltransferase pmt1-pmt22 complex bound to the sugar donor Phyre2 PDB 5f15 chain A Region: 14 - 393 Aligned: 343 Modelled: 353 Confidence: 99.7% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:4-amino-4-deoxy-l-arabinose (l-ara4n) transferase; PDBTitle: crystal structure of arnt from cupriavidus metallidurans bound to2 undecaprenyl phosphate Phyre2 PDB 6p25 chain A Region: 2 - 408 Aligned: 397 Modelled: 407 Confidence: 99.6% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:dolichyl-phosphate-mannose--protein mannosyltransferase 1; PDBTitle: structure of s. cerevisiae protein o-mannosyltransferase pmt1-pmt22 complex bound to the sugar donor and a peptide acceptor Phyre2 PDB 3waj chain A Region: 12 - 471 Aligned: 447 Modelled: 460 Confidence: 99.3% Identity: 12% PDB header:transferase Chain: A: PDB Molecule:transmembrane oligosaccharyl transferase; PDBTitle: crystal structure of the archaeoglobus fulgidus2 oligosaccharyltransferase (o29867_arcfu) complex with zn and sulfate Phyre2 PDB 3rce chain A Region: 8 - 431 Aligned: 405 Modelled: 409 Confidence: 99.1% Identity: 10% PDB header:transferase/peptide Chain: A: PDB Molecule:oligosaccharide transferase to n-glycosylate proteins; PDBTitle: bacterial oligosaccharyltransferase pglb Phyre2 PDB 6ezn chain F Region: 9 - 433 Aligned: 401 Modelled: 410 Confidence: 98.8% Identity: 13% PDB header:membrane protein Chain: F: PDB Molecule:dolichyl-diphosphooligosaccharide--protein PDBTitle: cryo-em structure of the yeast oligosaccharyltransferase (ost) complex Phyre2 PDB 1lur chain A Region: 518 - 565 Aligned: 47 Modelled: 48 Confidence: 56.4% Identity: 17% Fold: Supersandwich Superfamily: Galactose mutarotase-like Family: Aldose 1-epimerase (mutarotase) Phyre2 PDB 1wxm chain A domain 1 Region: 533 - 552 Aligned: 20 Modelled: 20 Confidence: 50.2% Identity: 25% Fold: beta-Grasp (ubiquitin-like) Superfamily: Ubiquitin-like Family: Ras-binding domain, RBD Phyre2 PDB 4rdb chain A Region: 439 - 561 Aligned: 96 Modelled: 106 Confidence: 45.8% Identity: 27% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:immunoreactive 32 kda antigen pg49; PDBTitle: crystal structure of an immunoreactive 32 kda antigen pg49 (pg_0181)2 from porphyromonas gingivalis w83 at 1.45 a resolution (psi community3 target, nakayama) Phyre2 PDB 5n1t chain M Region: 456 - 533 Aligned: 77 Modelled: 78 Confidence: 45.2% Identity: 21% PDB header:oxidoreductase Chain: M: PDB Molecule:copc; PDBTitle: crystal structure of complex between flavocytochrome c and copper2 chaperone copc from t. paradoxus Phyre2 PDB 4adj chain B Region: 451 - 590 Aligned: 132 Modelled: 140 Confidence: 43.6% Identity: 18% PDB header:viral protein Chain: B: PDB Molecule:e1 envelope glycoprotein; PDBTitle: crystal structure of the rubella virus glycoprotein e1 in its2 post-fusion form crystallized in presence of 1mm of calcium acetate Phyre2 PDB 6cd2 chain C Region: 501 - 559 Aligned: 59 Modelled: 59 Confidence: 37.9% Identity: 14% PDB header:membrane protein/chaperone Chain: C: PDB Molecule:outer membrane usher protein papc; PDBTitle: crystal structure of the papc usher bound to the chaperone-adhesin2 papd-papg Phyre2 PDB 6nfq chain C Region: 465 - 533 Aligned: 68 Modelled: 69 Confidence: 31.5% Identity: 13% PDB header:metal binding protein Chain: C: PDB Molecule:copc; PDBTitle: copc from pseudomonas fluorescens Phyre2 PDB 3ohn chain A Region: 524 - 585 Aligned: 62 Modelled: 62 Confidence: 30.2% Identity: 15% PDB header:membrane protein Chain: A: PDB Molecule:outer membrane usher protein fimd; PDBTitle: crystal structure of the fimd translocation domain Phyre2 PDB 2f2h chain A domain 1 Region: 537 - 583 Aligned: 47 Modelled: 47 Confidence: 29.2% Identity: 28% Fold: Putative glucosidase YicI, C-terminal domain Superfamily: Putative glucosidase YicI, C-terminal domain Family: Putative glucosidase YicI, C-terminal domain Phyre2 PDB 4dip chain D Region: 477 - 554 Aligned: 76 Modelled: 78 Confidence: 24.5% Identity: 18% PDB header:isomerase Chain: D: PDB Molecule:peptidyl-prolyl cis-trans isomerase fkbp14; PDBTitle: crystal structure of human peptidyl-prolyl cis-trans isomerase fkbp14 Phyre2 PDB 2w1w chain B Region: 519 - 585 Aligned: 67 Modelled: 67 Confidence: 22.1% Identity: 13% PDB header:hydrolase Chain: B: PDB Molecule:lipolytic enzyme, g-d-s-l; PDBTitle: native structure of a family 35 carbohydrate binding module2 from clostridium thermocellum Phyre2 PDB 5yxi chain A Region: 531 - 552 Aligned: 22 Modelled: 22 Confidence: 21.3% Identity: 23% PDB header:de novo protein Chain: A: PDB Molecule:drafx6; PDBTitle: designed protein drafx6 Phyre2 PDB 3k8r chain A Region: 527 - 578 Aligned: 52 Modelled: 52 Confidence: 19.7% Identity: 17% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of protein of unknown function (yp_427503.1) from2 rhodospirillum rubrum atcc 11170 at 2.75 a resolution Phyre2 PDB 4jja chain A Region: 409 - 491 Aligned: 83 Modelled: 83 Confidence: 19.1% Identity: 12% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein; PDBTitle: crystal structure of a duf1343 family protein (bf0379) from2 bacteroides fragilis nctc 9343 at 1.30 a resolution Phyre2 1 c6p2rB_ 2 c5f15A_ 3 c6p25A_ 4 c3wajA_ 5 c3rceA_ 6 c6eznF_ 7 d1lura_ 8 d1wxma1 9 c4rdbA_ 10 c5n1tM_ 11 c4adjB_ 12 c6cd2C_ 13 c6nfqC_ 14 c3ohnA_ 15 d2f2ha1 16 c4dipD_ 17 c2w1wB_ 18 c5yxiA_ 19 c3k8rA_ 20 c4jjaA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99