1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		L	P	G	R	V	F	A	S	P	A	D	F	N	T	Q	L	Q	A	W	L	V	R	A	N	H	R	Q	H	R	V	L	G	C	R	P	A	D	R	I	E	A	D	T	A	A	M	L	T	L	P	P	V	G	P	S	I	G	W	R	T
Secondary structure
SS confidence
Disorder		?	?	?	?																										?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	T	R	L	P	R	D	H	Y	V	R	L	D	G	N	D	Y	S	V	H	P	V	A	I	G	R	R	I	E	I	T	A	D	L	S	R	V	R	V	W	C	G	G	T	L	V	A	D	H	D	R	I	W	A	K	H	Q	T	I	S
Secondary structure
SS confidence
Disorder																																																								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.
Sequence		D	P	E	H	V	V	A	A	K	L	L	R	R	K	R	F	D	I	V	G	P	P	H	H	V	E	V	E	Q	R	L	L	T	T	Y	D	T	V	L	G	L	D	G	P	V	A
Secondary structure
SS confidence
Disorder										?	?	?	?	?	?	?	?	?	?	?																						?		?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 14%) Alpha helix ( 33%) Beta strand ( 28%)

Rank Aligned region

PDB 4fcy chain A Region: 8 - 108 Aligned: 101 Modelled: 101 Confidence: 98.8% Identity: 18% PDB header:dna binding protein/dna Chain: A: PDB Molecule:transposase; PDBTitle: crystal structure of the bacteriophage mu transpososome Phyre2 PDB 1bco chain A Region: 9 - 108 Aligned: 100 Modelled: 99 Confidence: 98.1% Identity: 11% PDB header:transposase Chain: A: PDB Molecule:bacteriophage mu transposase; PDBTitle: bacteriophage mu transposase core domain Phyre2 PDB 1bco chain A domain 1 Region: 62 - 108 Aligned: 47 Modelled: 47 Confidence: 96.4% Identity: 17% Fold: mu transposase, C-terminal domain Superfamily: mu transposase, C-terminal domain Family: mu transposase, C-terminal domain Phyre2 PDB 1c6v chain A Region: 12 - 39 Aligned: 28 Modelled: 28 Confidence: 74.4% Identity: 25% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: Retroviral integrase, catalytic domain Phyre2 PDB 1bco chain A domain 2 Region: 2 - 33 Aligned: 32 Modelled: 32 Confidence: 68.9% Identity: 19% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: mu transposase, core domain Phyre2 PDB 4uhp chain A Region: 1 - 18 Aligned: 18 Modelled: 18 Confidence: 56.9% Identity: 39% PDB header:hydrolase Chain: A: PDB Molecule:large component of pyocin ap41; PDBTitle: crystal structure of the pyocin ap41 dnase-immunity complex Phyre2 PDB 4qko chain H Region: 1 - 22 Aligned: 22 Modelled: 22 Confidence: 56.7% Identity: 27% PDB header:antimicrobial protein Chain: H: PDB Molecule:pyocin-s2; PDBTitle: the crystal structure of the pyocin s2 nuclease domain, immunity2 protein complex at 1.8 angstroms Phyre2 PDB 2jb0 chain B domain 1 Region: 1 - 22 Aligned: 22 Modelled: 22 Confidence: 56.3% Identity: 23% Fold: His-Me finger endonucleases Superfamily: His-Me finger endonucleases Family: HNH-motif Phyre2 PDB 7cei chain B Region: 1 - 18 Aligned: 18 Modelled: 18 Confidence: 55.0% Identity: 28% PDB header:immune system Chain: B: PDB Molecule:protein (colicin e7 immunity protein); PDBTitle: the endonuclease domain of colicin e7 in complex with its inhibitor2 im7 protein Phyre2 PDB 3i3l chain A Region: 7 - 31 Aligned: 25 Modelled: 25 Confidence: 47.0% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:alkylhalidase cmls; PDBTitle: crystal structure of cmls, a flavin-dependent halogenase Phyre2 PDB 3u1q chain B Region: 50 - 120 Aligned: 70 Modelled: 71 Confidence: 45.8% Identity: 21% PDB header:peptidoglycan binding protein Chain: B: PDB Molecule:mycobacteria tuberculosis ld-transpeptidase type 2; PDBTitle: crystal structure of m. tuberculosis ld-transpeptidase type 2 with 2-2 mercaptoethanol Phyre2 PDB 2gyk chain B domain 1 Region: 1 - 22 Aligned: 22 Modelled: 22 Confidence: 40.4% Identity: 23% Fold: His-Me finger endonucleases Superfamily: His-Me finger endonucleases Family: HNH-motif Phyre2 PDB 4jmx chain A Region: 84 - 120 Aligned: 37 Modelled: 37 Confidence: 30.4% Identity: 16% PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:probable l,d-transpeptidase ldta; PDBTitle: structure of ld transpeptidase ldtmt1 in complex with imipenem Phyre2 PDB 3dlr chain A Region: 12 - 39 Aligned: 28 Modelled: 28 Confidence: 27.6% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:integrase; PDBTitle: crystal structure of the catalytic core domain from pfv integrase Phyre2 PDB 6ed2 chain A Region: 74 - 115 Aligned: 42 Modelled: 42 Confidence: 27.3% Identity: 24% PDB header:hydrolase Chain: A: PDB Molecule:glycosyl hydrolase family 2, tim barrel domain protein; PDBTitle: faecalibacterium prausnitzii beta-glucuronidase Phyre2 PDB 5ew5 chain C Region: 1 - 18 Aligned: 18 Modelled: 18 Confidence: 25.6% Identity: 28% PDB header:hydrolase Chain: C: PDB Molecule:colicin-e9; PDBTitle: crystal structure of colicin e9 in complex with its immunity protein2 im9 Phyre2 PDB 3fn9 chain B Region: 74 - 110 Aligned: 37 Modelled: 37 Confidence: 25.1% Identity: 16% PDB header:hydrolase Chain: B: PDB Molecule:putative beta-galactosidase; PDBTitle: crystal structure of putative beta-galactosidase from bacteroides2 fragilis Phyre2 PDB 6eca chain A Region: 74 - 118 Aligned: 45 Modelled: 45 Confidence: 24.9% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:beta-glucuronidase; PDBTitle: lactobacillus rhamnosus beta-glucuronidase Phyre2 PDB 6d1p chain B Region: 74 - 110 Aligned: 37 Modelled: 37 Confidence: 24.1% Identity: 14% PDB header:hydrolase Chain: B: PDB Molecule:glycosyl hydrolases family 2, sugar binding domain protein; PDBTitle: apo structure of bacteroides uniformis beta-glucuronidase 3 Phyre2 PDB 6mvg chain B Region: 74 - 110 Aligned: 37 Modelled: 37 Confidence: 23.7% Identity: 14% PDB header:hydrolase Chain: B: PDB Molecule:beta-glucuronidase; PDBTitle: crystal structure of fmn-binding beta-glucuronidase from ruminococcus2 gnavus Phyre2 1 c4fcyA_ 2 c1bcoA_ 3 d1bcoa1 4 d1c6va_ 5 d1bcoa2 6 c4uhpA_ 7 c4qkoH_ 8 d2jb0b1 9 c7ceiB_ 10 c3i3lA_ 11 c3u1qB_ 12 d2gykb1 13 c4jmxA_ 14 c3dlrA_ 15 c6ed2A_ 16 c5ew5C_ 17 c3fn9B_ 18 c6ecaA_ 19 c6d1pB_ 20 c6mvgB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89