1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	D	V	D	A	F	L	L	T	N	R	G	T	W	D	R	L	D	H	L	I	K	K	R	H	S	L	S	G	A	E	I	D	E	L	V	E	L	Y	Q	R	V	S	T	H	L	S	M	L	R	S	A	S	S	D	Q	L	M	T	G
Secondary structure
SS confidence
Disorder		?	?																				?	?	?	?	?	?	?																								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	L	S	S	L	V	A	R	A	R	S	A	V	T	G	A	H	A	P	L	T	R	T	F	I	R	F	W	T	V	S	F	P	V	V	A	Y	R	T	W	R	W	W	L	A	T	A	V	A	F	F	A	V	V	V	L	I	G	F	W
Secondary structure
SS confidence
Disorder															?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	A	G	S	H	E	V	Q	S	A	I	G	T	P	T	E	I	D	E	L	V	S	H	D	V	Q	S	Y	Y	S	E	H	P	A	A	S	F	A	L	Q	V	W	V	N	N	S	W	V	A	T	T	C	I	A	M	S	V	V	L	G
Secondary structure
SS confidence
Disorder												?													?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	P	I	P	L	V	L	F	D	N	A	A	N	V	G	L	I	A	G	L	M	F	Q	A	G	K	G	D	F	L	L	G	L	L	L	P	H	G	L	L	E	L	T	A	V	F	L	A	A	A	I	G	M	R	L	G	W	S	V	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		S	A	G	N	R	P	R	G	Q	V	L	A	E	Q	G	R	G	V	V	S	V	A	V	G	L	V	G	V	F	L	V	A	G	L	I	E	A	V	V	T	P	S	P	L	P	T	F	V	R	I	A	V	G	I	I	A	E	A	V	F
Secondary structure
SS confidence
Disorder							?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330
Sequence		L	S	Y	I	G	Y	F	G	R	R	A	A	Q	A	G	E	T	G	D	M	E	D	A	P	D	V	V	P	T	G
Secondary structure
SS confidence
Disorder														?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 13%) Alpha helix ( 83%) Beta strand ( 0%) TM helix ( 39%) (View membrane topology prediction)

Rank Aligned region

PDB 6hwh chain X Region: 256 - 329 Aligned: 74 Modelled: 74 Confidence: 92.2% Identity: 14% PDB header:electron transport Chain: X: PDB Molecule:cytochrome c oxidase polypeptide 4; PDBTitle: structure of a functional obligate respiratory supercomplex from2 mycobacterium smegmatis Phyre2 PDB 2lo0 chain B Region: 11 - 42 Aligned: 31 Modelled: 32 Confidence: 58.6% Identity: 19% PDB header:protein binding Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: solution structure of the get5 carboxyl domain from a. fumigatus Phyre2 PDB 2mom chain B Region: 280 - 315 Aligned: 34 Modelled: 36 Confidence: 58.2% Identity: 26% PDB header:membrane protein Chain: B: PDB Molecule:lysosome-associated membrane glycoprotein 2; PDBTitle: structural insights of tm domain of lamp-2a in dpc micelles Phyre2 PDB 2mom chain C Region: 280 - 315 Aligned: 34 Modelled: 36 Confidence: 58.2% Identity: 26% PDB header:membrane protein Chain: C: PDB Molecule:lysosome-associated membrane glycoprotein 2; PDBTitle: structural insights of tm domain of lamp-2a in dpc micelles Phyre2 PDB 1g7o chain A domain 1 Region: 2 - 69 Aligned: 63 Modelled: 63 Confidence: 56.8% Identity: 17% Fold: GST C-terminal domain-like Superfamily: GST C-terminal domain-like Family: Glutathione S-transferase (GST), C-terminal domain Phyre2 PDB 5lc5 chain C Region: 281 - 305 Aligned: 25 Modelled: 25 Confidence: 55.5% Identity: 12% PDB header:oxidoreductase Chain: C: PDB Molecule:nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, PDBTitle: structure of mammalian respiratory complex i, class2 Phyre2 PDB 3jcu chain I Region: 257 - 285 Aligned: 29 Modelled: 29 Confidence: 49.6% Identity: 24% PDB header:membrane protein Chain: I: PDB Molecule:protein photosystem ii reaction center protein i; PDBTitle: cryo-em structure of spinach psii-lhcii supercomplex at 3.2 angstrom2 resolution Phyre2 PDB 5ldw chain C Region: 281 - 305 Aligned: 25 Modelled: 25 Confidence: 47.6% Identity: 12% PDB header:oxidoreductase Chain: C: PDB Molecule:nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, PDBTitle: structure of mammalian respiratory complex i, class1 Phyre2 PDB 5yo8 chain B Region: 2 - 73 Aligned: 69 Modelled: 72 Confidence: 45.4% Identity: 17% PDB header:lyase Chain: B: PDB Molecule:tetraprenyl-beta-curcumene synthase; PDBTitle: crystal structure of beta-c25/c30/c35-prene synthase Phyre2 PDB 1all chain A Region: 22 - 114 Aligned: 87 Modelled: 93 Confidence: 41.6% Identity: 10% Fold: Globin-like Superfamily: Globin-like Family: Phycocyanin-like phycobilisome proteins Phyre2 PDB 3a0h chain I Region: 257 - 285 Aligned: 29 Modelled: 29 Confidence: 39.5% Identity: 21% PDB header:electron transport Chain: I: PDB Molecule:photosystem ii reaction center protein i; PDBTitle: crystal structure of i-substituted photosystem ii complex Phyre2 PDB 4po5 chain E Region: 22 - 114 Aligned: 87 Modelled: 93 Confidence: 38.0% Identity: 8% PDB header:photosynthesis Chain: E: PDB Molecule:allophycocyanin subunit alpha-b; PDBTitle: crystal structure of allophycocyanin b from synechocystis pcc 6803 Phyre2 PDB 2vml chain A Region: 22 - 114 Aligned: 87 Modelled: 93 Confidence: 37.8% Identity: 18% PDB header:photosynthesis Chain: A: PDB Molecule:phycocyanin alpha chain; PDBTitle: the monoclinic structure of phycocyanin from gloeobacter violaceus Phyre2 PDB 2axt chain I domain 1 Region: 258 - 285 Aligned: 28 Modelled: 28 Confidence: 35.8% Identity: 21% Fold: Single transmembrane helix Superfamily: Photosystem II reaction center protein I, PsbI Family: PsbI-like Phyre2 PDB 1ha7 chain B Region: 22 - 114 Aligned: 86 Modelled: 93 Confidence: 34.4% Identity: 16% Fold: Globin-like Superfamily: Globin-like Family: Phycocyanin-like phycobilisome proteins Phyre2 PDB 2c7j chain B Region: 22 - 114 Aligned: 87 Modelled: 93 Confidence: 33.1% Identity: 20% PDB header:electron transport Chain: B: PDB Molecule:phycoerythrocyanin beta chain; PDBTitle: phycoerythrocyanin from mastigocladus laminosus, 295 k, 3.0 a Phyre2 PDB 1cpc chain B Region: 22 - 114 Aligned: 87 Modelled: 93 Confidence: 32.9% Identity: 20% Fold: Globin-like Superfamily: Globin-like Family: Phycocyanin-like phycobilisome proteins Phyre2 PDB 1cpc chain A Region: 22 - 114 Aligned: 87 Modelled: 93 Confidence: 29.7% Identity: 21% Fold: Globin-like Superfamily: Globin-like Family: Phycocyanin-like phycobilisome proteins Phyre2 PDB 6ajj chain A Region: 166 - 302 Aligned: 134 Modelled: 137 Confidence: 29.5% Identity: 16% PDB header:membrane protein, hydrolase Chain: A: PDB Molecule:drug exporters of the rnd superfamily-like protein, PDBTitle: crystal structure of mycolic acid transporter mmpl3 from mycobacterium2 smegmatis complexed with ica38 Phyre2 PDB 2jo8 chain B Region: 17 - 41 Aligned: 25 Modelled: 25 Confidence: 28.6% Identity: 32% PDB header:transferase Chain: B: PDB Molecule:serine/threonine-protein kinase 4; PDBTitle: solution structure of c-terminal domain of human mammalian2 sterile 20-like kinase 1 (mst1) Phyre2 1 c6hwhX_ 2 c2lo0B_ 3 c2momB_ 4 c2momC_ 5 d1g7oa1 6 c5lc5c_ 7 c3jcuI_ 8 c5ldwc_ 9 c5yo8B_ 10 d1alla_ 11 c3a0hi_ 12 c4po5E_ 13 c2vmlA_ 14 d2axti1 15 d1ha7b_ 16 c2c7jB_ 17 d1cpcb_ 18 d1cpca_ 19 c6ajjA_ 20 c2jo8B_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99