1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	E	V	V	T	G	D	A	V	V	L	D	V	Q	I	A	Q	L	P	V	R	A	V	S	A	V	I	D	I	T	I	I	F	I	G	Y	I	L	G	L	M	L	W	A	T	A	L	T	Q	F	D	E	A	L	T	T	A	F	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																									?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		I	I	F	T	V	L	A	L	V	G	Y	P	L	V	W	E	T	A	T	R	G	R	S	V	G	K	I	V	M	G	L	R	V	V	S	D	D	G	G	P	E	R	F	R	Q	A	L	F	R	A	L	A	S	V	V	E	I	W	M	L
Secondary structure
SS confidence
Disorder																				?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	G	S	P	A	V	I	C	S	M	L	S	P	K	A	K	R	V	G	D	V	F	A	G	T	V	V	V	S	E	R	G	P	R	L	G	P	P	P	V	M	P	P	S	L	A	W	W	A	S	S	L	Q	L	S	G	L	T	A	G
Secondary structure
SS confidence
Disorder																																	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?			?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Q	A	E	V	A	R	Q	F	L	V	R	A	P	Q	L	D	P	A	L	R	E	Q	M	A	Y	R	I	A	G	D	V	V	A	R	I	A	P	P	P	P	P	G	V	P	P	Q	L	V	L	A	A	V	L	A	E	R	H	R	R	E
Secondary structure
SS confidence
Disorder															?	?																							?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	L	R	L	R	P	T	L	P	P	A	G	Q	A	P	W	A	Q	M	A	P	H	R	G	W	P	P	G	L	S	G	A	T	P	W	S	P	Q	Q	P	V	I	P	W	P	E	P	D	P	P	P	Q	A	A	P	W	P	Q	Q	A
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310
Sequence		P	D	G	P	G	F	S	P	P	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 33%) Alpha helix ( 51%) Beta strand ( 5%) TM helix ( 22%) (View membrane topology prediction)

Rank Aligned region

PDB 4nl6 chain C Region: 234 - 309 Aligned: 76 Modelled: 76 Confidence: 89.4% Identity: 14% PDB header:splicing Chain: C: PDB Molecule:survival motor neuron protein; PDBTitle: structure of the full-length form of the protein smn found in healthy2 patients Phyre2 PDB 6ezn chain H Region: 24 - 84 Aligned: 61 Modelled: 61 Confidence: 22.3% Identity: 20% PDB header:membrane protein Chain: H: PDB Molecule:dolichyl-diphosphooligosaccharide--protein PDBTitle: cryo-em structure of the yeast oligosaccharyltransferase (ost) complex Phyre2 PDB 2dkd chain A Region: 7 - 102 Aligned: 61 Modelled: 63 Confidence: 18.4% Identity: 25% PDB header:isomerase Chain: A: PDB Molecule:phosphoacetylglucosamine mutase; PDBTitle: crystal structure of n-acetylglucosamine-phosphate mutase,2 a member of the alpha-d-phosphohexomutase superfamily, in3 the product complex Phyre2 PDB 6hu9 chain N Region: 15 - 97 Aligned: 83 Modelled: 83 Confidence: 14.4% Identity: 16% PDB header:oxidoreductase/electron transport Chain: N: PDB Molecule:cytochrome b; PDBTitle: iii2-iv2 mitochondrial respiratory supercomplex from s. cerevisiae Phyre2 PDB 2zet chain D Region: 172 - 205 Aligned: 34 Modelled: 34 Confidence: 14.1% Identity: 29% PDB header:signaling protein Chain: D: PDB Molecule:melanophilin; PDBTitle: crystal structure of the small gtpase rab27b complexed with2 the slp homology domain of slac2-a/melanophilin Phyre2 PDB 6hwh chain L Region: 8 - 94 Aligned: 87 Modelled: 87 Confidence: 13.9% Identity: 15% PDB header:electron transport Chain: L: PDB Molecule:cytochrome c oxidase subunit 2; PDBTitle: structure of a functional obligate respiratory supercomplex from2 mycobacterium smegmatis Phyre2 PDB 6miz chain C Region: 27 - 140 Aligned: 96 Modelled: 101 Confidence: 13.7% Identity: 13% PDB header:membrane protein Chain: C: PDB Molecule:transient receptor potential cation channel subfamily m PDBTitle: human trpm2 ion channel in an adpr-bound state Phyre2 PDB 4bju chain B Region: 2 - 102 Aligned: 66 Modelled: 68 Confidence: 13.1% Identity: 26% PDB header:isomerase Chain: B: PDB Molecule:n-acetylglucosamine-phosphate mutase; PDBTitle: genetic and structural validation of aspergillus fumigatus2 n-acetylphosphoglucosamine mutase as an antifungal target Phyre2 PDB 2yev chain B Region: 14 - 97 Aligned: 84 Modelled: 84 Confidence: 12.7% Identity: 13% PDB header:electron transport Chain: B: PDB Molecule:cytochrome c oxidase subunit 2; PDBTitle: structure of caa3-type cytochrome oxidase Phyre2 PDB 2kpy chain A Region: 258 - 310 Aligned: 53 Modelled: 53 Confidence: 12.4% Identity: 23% PDB header:allergen Chain: A: PDB Molecule:major pollen allergen art v 1; PDBTitle: solution structure of the major allergen of artemisia vulgaris (art v2 1) Phyre2 PDB 2m76 chain A Region: 5 - 14 Aligned: 10 Modelled: 10 Confidence: 12.0% Identity: 20% PDB header:signaling protein Chain: A: PDB Molecule:carnitine o-palmitoyltransferase 1, brain isoform; PDBTitle: structure of the regulatory domain of human brain carnitine2 palmitoyltransferase 1 Phyre2 PDB 1td4 chain A Region: 79 - 100 Aligned: 21 Modelled: 22 Confidence: 10.2% Identity: 24% Fold: beta-clip Superfamily: Head decoration protein D (gpD, major capsid protein D) Family: Head decoration protein D (gpD, major capsid protein D) Phyre2 PDB 2f1l chain A domain 1 Region: 88 - 102 Aligned: 15 Modelled: 15 Confidence: 9.8% Identity: 20% Fold: PRC-barrel domain Superfamily: PRC-barrel domain Family: RimM C-terminal domain-like Phyre2 PDB 6fkh chain E Region: 1 - 13 Aligned: 13 Modelled: 13 Confidence: 9.7% Identity: 23% PDB header:membrane protein Chain: E: PDB Molecule:atp synthase subunit alpha, chloroplastic; PDBTitle: chloroplast f1fo conformation 2 Phyre2 PDB 2voy chain B Region: 7 - 45 Aligned: 39 Modelled: 39 Confidence: 9.6% Identity: 8% PDB header:hydrolase Chain: B: PDB Molecule:sarcoplasmic/endoplasmic reticulum calcium atpase 1; PDBTitle: cryoem model of copa, the copper transporting atpase from2 archaeoglobus fulgidus Phyre2 PDB 4o7k chain A Region: 181 - 238 Aligned: 58 Modelled: 58 Confidence: 8.3% Identity: 12% PDB header:antitumor protein Chain: A: PDB Molecule:protein osa; PDBTitle: crystal structure of oncogenic suppression activity protein - a2 plasmid fertility inhibition factor Phyre2 PDB 4xtn chain J Region: 28 - 146 Aligned: 94 Modelled: 99 Confidence: 8.0% Identity: 6% PDB header:membrane protein Chain: J: PDB Molecule:sodium pumping rhodopsin; PDBTitle: crystal structure of the light-driven sodium pump kr2 in the2 pentameric red form, ph 4.9 Phyre2 PDB 1c5e chain A Region: 79 - 100 Aligned: 21 Modelled: 22 Confidence: 7.8% Identity: 24% Fold: beta-clip Superfamily: Head decoration protein D (gpD, major capsid protein D) Family: Head decoration protein D (gpD, major capsid protein D) Phyre2 PDB 5wsn chain C Region: 77 - 139 Aligned: 63 Modelled: 63 Confidence: 7.8% Identity: 17% PDB header:virus Chain: C: PDB Molecule:e protein; PDBTitle: structure of japanese encephalitis virus Phyre2 PDB 2d3f chain F Region: 273 - 298 Aligned: 26 Modelled: 26 Confidence: 7.7% Identity: 35% PDB header:structural protein Chain: F: PDB Molecule:collagen model peptides (pro-pro-gly)4-pro-hyp- PDBTitle: crystal structures of collagen model peptides (pro-pro-gly)2 4-pro-hyp-gly-(pro-pro-gly)4 Phyre2 1 c4nl6C_ 2 c6eznH_ 3 c2dkdA_ 4 c6hu9n_ 5 c2zetD_ 6 c6hwhL_ 7 c6mizC_ 8 c4bjuB_ 9 c2yevB_ 10 c2kpyA_ 11 c2m76A_ 12 d1td4a_ 13 d2f1la1 14 c6fkhe_ 15 c2voyB_ 16 c4o7kA_ 17 c4xtnJ_ 18 d1c5ea_ 19 c5wsnC_ 20 c2d3fF_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53