1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	T	S	P	E	Q	L	A	C	H	L	A	R	A	R	A	R	T	L	R	L	V	D	F	D	D	A	E	L	C	C	Q	Y	D	P	L	M	S	P	L	V	W	D	L	A	H	I	G	Q	Q	E	E	L	W	L	L	R	G	G	D
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	G	Q	P	G	L	L	P	P	A	V	E	G	L	Y	D	A	F	E	H	S	R	A	S	R	V	E	L	P	L	L	S	P	A	R	A	R	S	Y	C	A	T	V	R	S	A	A	L	D	A	L	A	A	L	P	E	D	G	D	S
Secondary structure
SS confidence
Disorder				?	?																		?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		F	V	F	A	M	V	I	S	H	E	N	Q	H	D	E	T	M	L	Q	A	L	N	L	R	T	G	S	P	L	L	A	A	T	S	A	L	P	A	G	R	P	R	M	A	G	T	S	V	L	V	A	G	G	P	F	V	L	G	V	D
Secondary structure
SS confidence
Disorder																								?	?	?	?	?	?	?	?	?	?	?	?	?	?		?	?	?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	A	D	E	P	C	S	L	D	N	E	R	P	A	H	V	V	D	V	P	A	F	R	I	G	R	V	P	V	T	N	G	E	W	Q	D	F	I	D	D	G	G	Y	T	Q	S	R	W	W	S	E	R	G	W	Q	H	R	Q	R	A
Secondary structure
SS confidence
Disorder			?	?	?	?	?	?	?	?	?																																							?	?									?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		G	L	T	A	P	Q	F	W	R	S	G	G	R	T	R	T	R	F	G	H	V	E	D	I	P	A	D	E	P	V	Q	H	V	S	Y	F	E	A	E	A	Y	A	A	W	A	G	A	R	L	P	T	E	V	E	W	E	K	A	C	A
Secondary structure
SS confidence
Disorder													?	?	?						?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		W	D	P	A	T	G	S	R	R	R	Y	P	W	G	T	E	E	P	T	D	T	Y	A	N	L	G	G	Q	T	L	R	P	A	P	V	G	A	Y	P	A	G	A	S	A	C	G	A	E	Q	M	L	G	D	V	W	E	W	T	T	S
Secondary structure
SS confidence
Disorder				?	?	?	?	?																																?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		P	L	R	P	W	P	G	F	V	P	M	V	Y	E	R	Y	S	Q	P	F	F	G	G	D	Y	R	V	L	R	G	G	S	W	A	V	E	P	A	I	L	R	P	S	F	R	N	W	D	H	P	Y	R	R	Q	I	F	A	G	V	R
Secondary structure
SS confidence
Disorder											?	?	?							?																															?	?	?
Disorder confidence
		.	.	.	.	.
Sequence		L	A	W	D	I
Secondary structure
SS confidence
Disorder					?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 14%) Alpha helix ( 31%) Beta strand ( 9%)

Rank Aligned region

PDB 4x8b chain A Region: 3 - 425 Aligned: 422 Modelled: 423 Confidence: 100.0% Identity: 81% PDB header:oxidoreductase Chain: A: PDB Molecule:sulfoxide synthase egtb; PDBTitle: ergothioneine-biosynthetic sulfoxide synthase egtb, apo form Phyre2 PDB 6qkj chain A Region: 1 - 425 Aligned: 392 Modelled: 392 Confidence: 100.0% Identity: 33% PDB header:oxidoreductase Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: egtb from chloracidobacterium thermophilum, a type ii sulfoxide2 synthase in complex with n,n,n-trimethyl-histidine Phyre2 PDB 5hha chain B Region: 161 - 425 Aligned: 237 Modelled: 246 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: B: PDB Molecule:pvdo; PDBTitle: structure of pvdo from pseudomonas aeruginosa Phyre2 PDB 1z70 chain X domain 1 Region: 163 - 425 Aligned: 253 Modelled: 263 Confidence: 100.0% Identity: 28% Fold: C-type lectin-like Superfamily: C-type lectin-like Family: Sulfatase-modifying factor-like Phyre2 PDB 2q17 chain C Region: 161 - 425 Aligned: 257 Modelled: 265 Confidence: 100.0% Identity: 31% PDB header:unknown function Chain: C: PDB Molecule:formylglycine generating enzyme; PDBTitle: formylglycine generating enzyme from streptomyces coelicolor Phyre2 PDB 1y1f chain X Region: 163 - 425 Aligned: 252 Modelled: 263 Confidence: 100.0% Identity: 28% PDB header:oxidoreductase Chain: X: PDB Molecule:c-alpha-formyglycine-generating enzyme; PDBTitle: human formylglycine generating enzyme with cysteine sulfenic acid Phyre2 PDB 5nyy chain A Region: 165 - 424 Aligned: 254 Modelled: 260 Confidence: 100.0% Identity: 29% PDB header:transferase Chain: A: PDB Molecule:non-specific serine/threonine protein kinase; PDBTitle: formylglycine generating enzyme from t. curvata in complex with cd(ii) Phyre2 PDB 1y4j chain A domain 1 Region: 165 - 424 Aligned: 237 Modelled: 244 Confidence: 100.0% Identity: 32% Fold: C-type lectin-like Superfamily: C-type lectin-like Family: Sulfatase-modifying factor-like Phyre2 PDB 2y3c chain A Region: 161 - 423 Aligned: 243 Modelled: 261 Confidence: 100.0% Identity: 23% PDB header:unknown function Chain: A: PDB Molecule:treponema denticola variable protein 1; PDBTitle: treponema denticola variable protein 1 Phyre2 PDB 5aoh chain A Region: 163 - 425 Aligned: 220 Modelled: 227 Confidence: 100.0% Identity: 24% PDB header:unknown function Chain: A: PDB Molecule:carf; PDBTitle: crystal structure of carf Phyre2 PDB 1yu0 chain A domain 2 Region: 190 - 424 Aligned: 200 Modelled: 211 Confidence: 100.0% Identity: 16% Fold: C-type lectin-like Superfamily: C-type lectin-like Family: Mtd variable domain Phyre2 PDB 1yu3 chain A domain 2 Region: 190 - 424 Aligned: 200 Modelled: 211 Confidence: 100.0% Identity: 18% Fold: C-type lectin-like Superfamily: C-type lectin-like Family: Mtd variable domain Phyre2 PDB 2iou chain C Region: 264 - 424 Aligned: 150 Modelled: 161 Confidence: 100.0% Identity: 18% PDB header:viral protein/membrane protein Chain: C: PDB Molecule:major tropism determinant p1; PDBTitle: major tropism determinant p1 (mtd-p1) variant complexed with2 bordetella brochiseptica virulence factor pertactin extracellular3 domain (prn-e). Phyre2 PDB 5vf4 chain A Region: 167 - 422 Aligned: 206 Modelled: 218 Confidence: 100.0% Identity: 23% PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: thermus aquaticus variable protein (taqvp) from diversity-generating2 retroelements (dgr) Phyre2 PDB 5wk0 chain A Region: 7 - 144 Aligned: 133 Modelled: 135 Confidence: 99.6% Identity: 11% PDB header:unknown function Chain: A: PDB Molecule:damage-inducible protein dinb; PDBTitle: crystal structure of the bacillithiol transferase bsta from2 staphylococcus aureus. Phyre2 PDB 6iz2 chain A Region: 1 - 150 Aligned: 127 Modelled: 127 Confidence: 99.2% Identity: 17% PDB header:unknown function Chain: A: PDB Molecule:dinb/yfit family protein; PDBTitle: crystal structure of dinb/yfit protein dr0053 from d. radiodurans r1 Phyre2 PDB 2ou6 chain A domain 1 Region: 5 - 145 Aligned: 139 Modelled: 141 Confidence: 99.2% Identity: 18% Fold: DinB/YfiT-like putative metalloenzymes Superfamily: DinB/YfiT-like putative metalloenzymes Family: DinB-like Phyre2 PDB 3cex chain B Region: 5 - 144 Aligned: 139 Modelled: 140 Confidence: 99.1% Identity: 15% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of the conserved protein of locus ef_3021 from2 enterococcus faecalis Phyre2 PDB 3di5 chain A Region: 2 - 149 Aligned: 130 Modelled: 130 Confidence: 98.8% Identity: 18% PDB header:metal binding protein Chain: A: PDB Molecule:dinb-like protein; PDBTitle: crystal structure of a dinb-like protein (bce_4655) from bacillus2 cereus atcc 10987 at 2.01 a resolution Phyre2 PDB 3dka chain A Region: 5 - 150 Aligned: 123 Modelled: 123 Confidence: 98.7% Identity: 13% PDB header:unknown function Chain: A: PDB Molecule:dinb-like protein; PDBTitle: crystal structure of a dinb-like protein (yjoa, bsu12410) from2 bacillus subtilis at 2.30 a resolution Phyre2 1 c4x8bA_ 2 c6qkjA_ 3 c5hhaB_ 4 d1z70x1 5 c2q17C_ 6 c1y1fX_ 7 c5nyyA_ 8 d1y4ja1 9 c2y3cA_ 10 c5aohA_ 11 d1yu0a2 12 d1yu3a2 13 c2iouC_ 14 c5vf4A_ 15 c5wk0A_ 16 c6iz2A_ 17 d2ou6a1 18 c3cexB_ 19 c3di5A_ 20 c3dkaA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106