1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	D	V	I	R	W	A	R	R	L	A	V	V	A	G	T	A	A	A	V	T	T	P	G	L	L	S	A	H	V	P	M	V	S	A	E	P	C	P	D	V	E	V	V	F	A	R	G	T	G	E	P	P	G	I	G	S	V	G	G
Secondary structure
SS confidence
Disorder		?	?																								?	?	?	?	?	?	?	?	?	?	?																		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80
Sequence		L	F	V	D	A	L	R	F	P	G	W	R	Q	V	T	R	G	L	R	R
Secondary structure
SS confidence
Disorder																			?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 22%) Alpha helix ( 68%) Beta strand ( 9%) TM helix ( 20%) (View membrane topology prediction)

Rank Aligned region

PDB 4psd chain A Region: 1 - 69 Aligned: 69 Modelled: 69 Confidence: 99.2% Identity: 26% PDB header:hydrolase Chain: A: PDB Molecule:carbohydrate esterase family 5; PDBTitle: structure of trichoderma reesei cutinase native form. Phyre2 PDB 4oyl chain C Region: 32 - 69 Aligned: 38 Modelled: 38 Confidence: 98.9% Identity: 39% PDB header:hydrolase Chain: C: PDB Molecule:cutinase; PDBTitle: humicola insolens cutinase in complex with mono-ethylphosphate Phyre2 PDB 2czq chain B Region: 33 - 69 Aligned: 37 Modelled: 37 Confidence: 98.9% Identity: 24% PDB header:hydrolase Chain: B: PDB Molecule:cutinase-like protein; PDBTitle: a novel cutinase-like protein from cryptococcus sp. Phyre2 PDB 1cex chain A Region: 32 - 69 Aligned: 38 Modelled: 38 Confidence: 98.8% Identity: 26% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Cutinase-like Phyre2 PDB 5x88 chain A Region: 36 - 69 Aligned: 34 Modelled: 34 Confidence: 98.8% Identity: 41% PDB header:hydrolase Chain: A: PDB Molecule:cutinase; PDBTitle: a crystal structure of cutinases from malbranchea cinnamomea Phyre2 PDB 3gbs chain A Region: 33 - 69 Aligned: 37 Modelled: 37 Confidence: 98.5% Identity: 30% PDB header:hydrolase Chain: A: PDB Molecule:cutinase 1; PDBTitle: crystal structure of aspergillus oryzae cutinase Phyre2 PDB 3dd5 chain F Region: 32 - 69 Aligned: 38 Modelled: 38 Confidence: 98.4% Identity: 39% PDB header:hydrolase Chain: F: PDB Molecule:cutinase; PDBTitle: glomerella cingulata e600-cutinase complex Phyre2 PDB 1qoz chain A Region: 38 - 69 Aligned: 31 Modelled: 32 Confidence: 98.2% Identity: 32% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Cutinase-like Phyre2 PDB 1g66 chain A Region: 37 - 69 Aligned: 32 Modelled: 33 Confidence: 98.1% Identity: 34% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Cutinase-like Phyre2 PDB 3aja chain A Region: 36 - 69 Aligned: 34 Modelled: 34 Confidence: 97.8% Identity: 29% PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of msmeg_6394 Phyre2 PDB 3hc7 chain A Region: 43 - 61 Aligned: 19 Modelled: 19 Confidence: 87.7% Identity: 26% PDB header:cell adhesion Chain: A: PDB Molecule:gene 12 protein; PDBTitle: crystal structure of lysin b from mycobacteriophage d29 Phyre2 PDB 2pv7 chain A domain 2 Region: 54 - 71 Aligned: 18 Modelled: 18 Confidence: 18.7% Identity: 56% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain Phyre2 PDB 1jms chain A domain 4 Region: 34 - 70 Aligned: 37 Modelled: 37 Confidence: 18.2% Identity: 11% Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: DNA polymerase beta-like Phyre2 PDB 3ing chain A Region: 54 - 69 Aligned: 16 Modelled: 16 Confidence: 16.1% Identity: 25% PDB header:oxidoreductase Chain: A: PDB Molecule:homoserine dehydrogenase; PDBTitle: crystal structure of homoserine dehydrogenase (np_394635.1) from2 thermoplasma acidophilum at 1.95 a resolution Phyre2 PDB 3b20 chain R Region: 54 - 71 Aligned: 18 Modelled: 18 Confidence: 15.6% Identity: 22% PDB header:oxidoreductase Chain: R: PDB Molecule:glyceraldehyde 3-phosphate dehydrogenase (nadp+); PDBTitle: crystal structure of glyceraldehyde-3-phosphate dehydrogenase2 complexed with nadfrom synechococcus elongatus" Phyre2 PDB 1hdg chain O Region: 54 - 71 Aligned: 18 Modelled: 18 Confidence: 15.2% Identity: 22% PDB header:oxidoreductase (aldehy(d)-nad(a)) Chain: O: PDB Molecule:holo-d-glyceraldehyde-3-phosphate dehydrogenase; PDBTitle: the crystal structure of holo-glyceraldehyde-3-phosphate dehydrogenase2 from the hyperthermophilic bacterium thermotoga maritima at 2.53 angstroms resolution Phyre2 PDB 5d5p chain C Region: 39 - 58 Aligned: 20 Modelled: 20 Confidence: 15.1% Identity: 35% PDB header:transferase Chain: C: PDB Molecule:hcgb; PDBTitle: hcgb from methanococcus maripaludis Phyre2 PDB 2d2i chain O Region: 54 - 71 Aligned: 18 Modelled: 18 Confidence: 14.5% Identity: 22% PDB header:oxidoreductase Chain: O: PDB Molecule:glyceraldehyde 3-phosphate dehydrogenase; PDBTitle: crystal structure of nadp-dependent glyceraldehyde-3-2 phosphate dehydrogenase from synechococcus sp. complexed3 with nadp+ Phyre2 PDB 5e38 chain D Region: 39 - 60 Aligned: 22 Modelled: 22 Confidence: 13.6% Identity: 36% PDB header:transferase Chain: D: PDB Molecule:uracil phosphoribosyltransferase; PDBTitle: structural basis of mapping the spontaneous mutations with 5-2 flourouracil in uracil phosphoribosyltransferase from mycobacterium3 tuberculosis Phyre2 PDB 3doc chain D Region: 54 - 71 Aligned: 18 Modelled: 18 Confidence: 12.9% Identity: 28% PDB header:oxidoreductase Chain: D: PDB Molecule:glyceraldehyde 3-phosphate dehydrogenase; PDBTitle: crystal structure of trka glyceraldehyde-3-phosphate dehydrogenase2 from brucella melitensis Phyre2 1 c4psdA_ 2 c4oylC_ 3 c2czqB_ 4 d1cexa_ 5 c5x88A_ 6 c3gbsA_ 7 c3dd5F_ 8 d1qoza_ 9 d1g66a_ 10 c3ajaA_ 11 c3hc7A_ 12 d2pv7a2 13 d1jmsa4 14 c3ingA_ 15 c3b20R_ 16 c1hdgO_ 17 c5d5pC_ 18 c2d2iO_ 19 c5e38D_ 20 c3docD_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91